Fig. 1 (above). Endometrial hyperplasia, simple. Hyperplastic glands of unequal size, some of which are cystically dilated Fig. 2 (below).
|
|
- Dwight Reeves
- 5 years ago
- Views:
Transcription
1 81 Fig. 1 (above). Endometrial hyperplasia, simple. Hyperplastic glands of unequal size, some of which are cystically dilated Fig. 2 (below). Endometrial hyperplasia, simple. Proliferative type epithelium lining cystically dilated glands. Compare proliferative stroma with that of an endometrial polyp (Fig. 8)
2 82 Fig. 3 (above). Endometrial hyperplasia, complex. Markedly crowded glands Fig.4 (below). Endometrial hyperplasia, complex. Crowded, architecturally abnormal glands without cytologic atypia
3 83 Fig. 5 (above). Atypical endometrial hyperplasia. Glandular epithelium showing nuclear atypia and loss of polarity Fig. 6 (below). Atypical endometrial hyperplasia. Atypical gland with large, irregular nuclei showing loss of polarity and containing prominent nucleoli and abundant cytoplasm, which was eosinophilic
4 84 Fig. 7 (above). Endometrial polyp. Dilated glands and dense stroma Fig. 8 (below). Endometrial polyp. Higher magnification of portion of Fig. 7, showing thick-walled blood vessels, one of which contains a thrombus, a dilated gland, and dense stroma
5 85 Fig.9 (above). Endometrioid adenocarcinoma, corpus. Crowded endometrioid glands that are back-to-back or separated by fibrotic stroma Fig.tO (below). Endometrioid adenocarcinoma, corpus. Back-to-back glands lined by cells with atypical nuclei
6 86 Fig.n. Endometrioid adenoarcinoma, corpus. Solid growth with minor gland formation Fig. U. Endometrioid adenocarcinoma, corpus. Villoglandular pattern
7 87 Fig.13. Endometrioid adenocarcinoma, secretory variant, corpus. Neoplastic glands resembling those of early secretory endometrium Fig.14. Endometrioid adenocarcinoma, ciliated cell variant, corpus. Well differentiated neoplastic glands lined by ciliated cells
8 88 Fig. IS (above). Adenocarcinoma with squamous differentiation (adenoacanthoma), corpus. Intraglandular morule Fig.I6 (below). Adenocarcinoma with squamous differentiation (adenosquamous carcinoma), corpus. Neoplastic glands blending with malignant squamous epithelium, which borders reactive stroma
9 89 Fig.17 (above). Adenocarcinoma with squamous differentiation (adenosquamous carcinoma), corpus. Poorly differentiated adenocarcinoma blending with malignant squamous component Fig. IS (below). Serous adenocarcinoma, corpus. Papillae with fibrous cores lined by poorly differentiated complex epithelium with exfoliation of cells into lumens
10 90 Fig.19. Mucinous adenocarcinoma, corpus. Glands and villi lined by neoplastic cells containing abundant mucin Fig. 20. Endometrial stromal nodule. Pushing border between tumour and compressed endometrium (above)
11 91 Fig. 21 (above). Endometrial stromal nodule. Tumour cells resembling normal proliferative endometrial stromal cells whirling around small arteries Fig. 22 (below). Endometrial stromal sarcoma, low grade. Extension of tumour into myometrium and distended thin-walled vessels
12 92...~.... ''' ' "... #... - f' --.,,..., ~... \ ~... r ""\I :..-=-. _...,r;.... ':.." ti ",!,.~.....,;..... ",....,.._ ~ - - ~..._- # - - ".... ',,:--.. ".... "', 7'.::... -,'.e.: :.,,..".., J... ~ -... :......, "....., ',... _ #-t'.,;..... ~ _... ~....., Fig. 23 (above). Endometrial stromal sarcoma, low grade. Cells resembling endometrial stromal cells surrounding numerous small arteries that resemble normal spiral arteries Fig. 24 (below). Endometrial stromal sarcoma, high grade. Pleomorphic, mitotically active tumour cells
13 93 Fig.25 (above). Leiomyoma, corpus. Intersecting fascicles of spindle cells lacking atypia Fig.26 (below). Leiomyoma, corpus. Hyaline bands separating groups of smooth muscle cells
14 94 Fig. 27 (above). Cellular leiomyoma, corpus. Tumour significantly more cellular than normal myometrium, but without nuclear atypia or mitotic activity Fig.28 (below). Epithelioid leiomyoma, corpus. Round tumour cells with abundant clear cytoplasm; no mitotic activity
15 95 Fig. 29. Epithelioid leiomyoma, corpus. Plexiform arrangement of epithelioid smooth muscle cells with dense cytoplasm Fig. 30. Bizarre leiomyoma, corpus. Numerous symplastic giant cells; no mitotic activity
16 96 Fig. 31 (above). Lipoieiomyoma, corpus. Intimate admixture of smooth muscle cells and lipocytes Fig. 32 (below). Leiomyosarcoma, corpus. Hypercellular tumour with nuclear pleomorphism, hyperchromatism, and mitotic figures
17 97 Fig.33 (above). Leiomyosarcoma, corpus. Prominent nuclear pleomorphism and atypical mitotic figure Fig.34 (below). Intravenous leiomyomatosis, corpus. Cytologically benign, focally hyalinized leiomyomatous tissue within myometrial veins
18 98 Fig. 35. Diffuse leiomyomatosis, corpus. Multiple, closely packed leiomyomas occupying most of myometrium Fig. 36. Mixed endometrial stromal and smooth muscle tumou/; corpus. Irregularly oval nodule of smooth muscle (above) present within otherwise typical endometrial stromal tumour
19 99 Fig. 37 (above). Adenomatoid tumour, corpus. Dilated tubules and small cysts extensively infiltrating the myometrium Fig. 38 (below). Adenomatoid tumour, corpus. Single layer of flattened tumour cells lining tubules and cysts in myometrium
20 100 Fig.39 (above). Atypical polypoid adenomyoma, corpus. Endometrial glands separated by fascicles of cellular smooth muscle Fig.40 (below). Atypical polypoid adenomyoma, corpus. Large foci of morular squamous metaplasia
21 101 Fig.41 (above). Adenosarcoma, homologous, corpus. Club-shaped polyps lived by benign appearing endometrioid epithelium, with hypercellular stromal component Fig.42 (below). Adenosarcoma, heterologous, corpus. Glands with focal squamous metaplasia surrounded by dense cuffs of neoplastic stromal cells, and islands of immature cartilage within less cellular stromal component
22 102 Fig. 43 (above). Carcinosarcoma, homologous, corpus. Carcinoma cells with a complex pattern lining polypoid masses of malignant-appearing stroma Fig. 44 (below). Carcinosarcoma, heterologous, corpus. Malignant-appearing glands and stroma containing strap-shaped rhabdomyoblasts
23 103 Fig.45 (above). Carcinosarcoma, heterologous, corpus. Large focus of malignantappearing osteoid and central focus of malignant squamous cells Fig. 46 (below). Sex cord-like tumour, corpus. Closely packed bands of well differentiated cells with an epithelial pattern, some of which have lipid-rich cytoplasm
24 104 Fig.47. Sex cord-like tumour, corpus. Irregular nests of cells separated by cellular fibrous tissue, resembling a granulosa cell tumour Fig.48. Glioma, corpus. Irregular islands of glial tissue invasive of myometrium
25 105 Fig.49 (above). Metastatic lobular carcinoma of breast origin, corpus. Diffuse replacement of endometrial stroma with two residual benign endometrial glands Fig. 50 (below). Squamous metaplasia, endometrium. Confluent squamous morules, which have replaced endometrial glands
26 106 Fig. 51. Mucinous metaplasia, endometrium. Surface epithelium mostly replaced by mucin-filled cells Fig.52. Hobnail cell metaplasia, endometrium. Uniform cells with bulbous, apical, bland appearing nuclei lining adjacent endometrial glands
27 107 Fig. 53. Clear cell change, endometrium. Closely packed hypersecretory glands containing regularly arranged papillae lined by large clear cells (from a pregnant patient) Fig. 54. Eosinophilic cell metaplasia, endometrium. Glands lined by single layer of cells with abundant cytoplasm, which was eosinophilic
28 108 Fig.55. Surface syncytial change, endometrium. Surface lined by an irregularly thick layer of cells with bland nuclei forming microcysts Fig.56. Papillary change, endometrium. Several dilated glands with papillae that are focally confluent and lined by cells with abundant cytoplasm
29 109 Fig.57. Arias-Stella change, endometrium. Closely packed glands with regularly arranged papillae lined by hobnail type cells Fig. 58. Arias-Stella change, endometrium. Lining cells with bulbous, apical nuclei, many of which have a smudgy appearance
30 110 Fig. 59. Foam cell change, endometrium. Vacuolated endometrial stromal cells filled with small lipid droplets Fig.60. Adenomyosis, corpus. Island of endometrial tissue in myometrium connected to endometrium
31 111 Fig. 61. Chronic endometritis. Stroma replaced by round cell infiltrate, which contained plasma cells, and glands that are hyperplastic and architecturally abnormal Fig.62. Lymphoma-like lesion, corpus. Polymorphous lymphoid infiltrate occupying stroma and eroding into an endometrial gland
32 112 Fig.63 (above). Inflammatory pseudotumour. corpus. Myometrial mass composed predominantly of spindle cells, plasma cells and lymphocytes Fig. 64 (below). Sixteen-day conceptus containing of chorionic vi/b, cytotrophoblast, syncytiotrophoblast and intermediate trophoblast (lower left)
33 113 Fig. 65 (above). Complete hydatidiform mole. Hydropic swelling with cistern formation and slight hyperplasia of trophoblast Fig. 66 (below). Complete hydatid(form mole. Trophoblastic hyperplasia
34 114 Fig. 67 (above). Complete hydatidiform mole. Trophoblastic atypia Fig.68 (below). Partial hydatidiform mole. Two populations of villi, one normal in size and the other showing hydropic swelling, some with a scalloped outline
35 115 Fig.69 (above). Partial hydatidiform mole. Two populations of villi, one normal and the other hydropic; minimal trophoblastic hyperplasia Fig. 70 (below). Partial hydatidiform mole. Trophoblastic inclusion
36 116 Fig. 71 (above). Abortus. Hydropic chorionic villi, one of which contains a cistern Fig.72 (below). Abortus. Hydropic change and polar orientation of trophoblast, which lacks atypia
37 117 Fig. 73 (above). Invasive hydatidiform mole. Molar villus exhibiting trophoblastic hyperplasia and detached nodule of hyperplastic trophoblast (left) within vascular space in myometrium Fig.74 (below). Choriocarcinoma, corpus. Predominant population of cytotrophoblast and intermediate trophoblast; syncytiotrophoblast lining vascular spaces
38 118 Fig.75 (above). Choriocarcinoma, corpus. Dimorphic pattern of cytotrophoblast and syncytiotrophoblast, with latter lining vascular spaces Fig. 76 (below). Choriocarcinoma, corpus. Cytotrophoblast and syncytiotrophoblast (right) and intermediate trophoblast (left)
39 119 Fig. 77 (above). Choriocarcinoma, corpus. Immunoreactive chorionic gonadotropin localized mainly in syncytiotrophoblast and, to a lesser extent, in intermediate trophoblastic cells (left) Fig. 78 (below). Placental site trophoblastic tumour. Predominant composition of intermediate trophoblast with single syncytiotrophoblastic cell and fibrinoid in vessel wall (lower right)
40 120 Fig. 79 (above). Placental site trophoblastic tumour. Infiltration of myometrium with separation of smooth muscle bundles Fig. SO (below). Placental site trophoblastic tumour (clinically malignant). Clarity of cytoplasm of some intermediate trophoblastic cells
41 121 Fig.81. Placental site trophoblastic tumour (clinically malignant). Nuclear atypia and mitotic figure (arrolv) Fig.82. Placental site trophoblastic tumour. Immunoreactive placental lactogen in intermediate trophoblastic cells
42 122 Fig. 83 (above). Exaggerated placental site. Intermediate trophoblastic cells without formation of confluent mass Fig.84 (below). Exaggerated placental site. Smudgy, degenerative appearance of nuclei despite marked pleomorphism
43 123 Fig. 85 (above). Placental site nodule. Well circumscribed margin and marked hyalinization of two nodules Fig. 86 (below). Placental site nodule. Intermediate trophoblastic cells without significant nuclear atypia
44 124 Fig.87. Squamous papilloma, cervix. Papilla lined by thick layer of cellular squamous epithelium lacking nuclear atypia Fig.88. Squamous metaplasia, cervix. Immature squamous epithelium undermining columnar, mucinous epithelium
45 125 Fig.89. Transitional metaplasia, cervix. Cervical surface epithelium replaced by transitional epithelial cells containing grooved, "coffee bean" nuclei Fig. 90. Squamous atypia, cervix. Thin layer of atypical surface epithelium overlying chronically inflamed cervical stroma
46 126 Fig.91. Mild dysplasia (CINI). Human papilloma-viral changes in upper portion of epithelium characterized by cytoplasmic clarity and abnormal nuclei Fig. 92. Mild dysplasia (ClNI). Koilocytotic atypia in superficial epithelial layer, characterized by cytoplasmic swelling and clarity, enlarged, hyperchromatic nuclei, and occasional binucleated cells
47 127 Fig. 93. Moderate dysplasia (CIN2). Cytoplasmic maturation and moderate nuclear atypia with numerous mitotic figures confined to lower half of epithelium Fig.94. Severe dysplasia (CIN3). Cytoplasmic maturation in upper portion of epithelium and nuclear abnormalities including atypical mitotic figures throughout epithelium
48 128 Fig. 95. Carcinoma in situ (CIN3). Nuclear abnormalities involving full thickness of the epithelium without cytoplasmic maturation Fig.96. Squamous cell carcinoma, microinvasive, cervix. Multiple buds of differentiating squamous cells extending into superficial cervical stroma
49 129 Fig.97. Squamous cell carcinoma, microinvasive, cervix. Single bud of differentiating squamous cells invading cervical stroma from gland involved by carcinoma in situ Fig. 98. Squamous cell carcinoma, microinvasive, cervix. Measurable tumour mass 3 mm in depth and 5 mm in lateral dimension
50 130 Fig.99. Squamous cell carcinoma, keratinizing, cervix. Irregular, invasive nests of malignant squamous cells, several of which contain central pearls Fig.100. Squamous cell carcinoma, nonkeratinizing, cervix. Irregular aggregate of squamous cells with abundant cytoplasm and without pearl formation
51 131 Fig. 101 (above). Squamous cell carcinoma, non-keratznizmg, cervix. Squamous cells with small, hyperchromatic nuclei and scanty cytoplasm growing in discrete nests separated by stroma Fig.I02 (below). Squamous cell carcinoma, non-keratinizing, cervix. Small squamous cells with differentiation and degeneration in center of nest
52 132 Fig.l03. Lymphoepithelioma-like carcmoma, cervix. Undifferentiated large neoplastic cells and extensive sprinkling of lymphocytes throughout tumour Fig Endocervical polyp. Polypoid mass composed of endocervical-type glands and fibrous stroma
53 133 Fig.lOS. Mullerian papilloma, cervix. Multiple small polypoid projections composed largely of chronically inflamed fibrous stroma and lined by simple epithelium, arising at squamocolumnar junction Fig Glandular dysplasia, cervix. Nuclear atypia, focal loss of nuclear polarity and loss of intracytoplasmic mucin
54 134 Fig Adenocarcinoma in situ, cervix. Glands lined by highly atypical columnar epithelium merging with squamous carcinoma in situ; atypical mitotic figures Fig.l0S. Adenocarcinoma in situ, cervix. Normal endocervical gland (left) and glands partly or completely replaced by highly atypical columnar epithelium (right)
55 135 Fig.l09. Mucinous adenocarcinoma, endocervical type, cervix. Glands lined by highly atypical endocervical type cells filled with mucin Fig.l10. Mucinous adenocarcinoma, endocervical type (adenoma malignum), cervix. Irregularly branching, large glands and small glands lined by mucin-rich cells infiltrating cervical wall
56 136 Fig.lli. Mucinous adenocarcinoma, endocervical type (adenoma malignum), cervix. Small, highly differentiated glands of endocervical type infiltrating muscle of cervical wall Fig. Ill. Mucinous adenocarcinoma, endocervical type, cervix. Villoglandular pattern
57 137 Fig Mucinous adenocarcinoma, endocervical type, cervix. Villoglandular pattern; moderately differentiated, stratified tumour cells devoid of mucin in this area Fig Mucinous adenocarcinoma, intestinal type, cervix. Neoplastic glandular epithelium containing numerous goblet cells
58 138 Fig.1lS. Endometrioid adenocarcinoma, cervix. Villoglandular pattern Fig.1l6. Mesonephric adenocarcinoma, cervix. Closely packed, small, round tubules filled with colloid-like material and arranged back-to-back, resembling normal mesonephric tubules
59 139 Fig Mesonephric adenocarcinoma, cervix. Mesonephric duct-like structures lined by stratified nonmucin-containing epithelium (left); hyperplastic mesonephric tubules (center and right) Fig.11S. Adenosquamous carcinoma, cervix. Squamous cell carcinoma (left) merging with adenocarcinoma (right)
60 140 Fig. 119 (above). Glassy cell carcinoma, cervix. Undifferentiated neoplastic cells with abundant ground-glass cytoplasm, central nuclei with prominent nucleoli and prominent cell membranes; atypical mitotic figures Fig.UO (below). Adenoid cystic carcinoma, cervix. Large, rounded nests with a cribriform pattern separated by fibrous stroma
61 141 Fig.12I. Adenoid cystic carcinoma, cervix. Anastomosing, thin bands of neoplastic epithelial cells separated by cylinders of hyalinized stroma Fig.I22. Adenoid basal carcinoma, cervix. Small nests of cells resembling basal cells, containing a few glandular spaces and undergoing squamous differentiation (upper center)
62 142 Fig.123. Adenoid basal carcinoma, cervix. Gland formation (upper center) Fig Carcinoid tumour, cervix. Nests and bands composed of uniform cells with round, hyperchromatic nuclei
63 143 Fig. US. Small cell carcinoma, cervix. Diffuse infiltration of uniform small cells occupying cervical stroma and surrounding an endocervical gland Fig.126. Small cell carcinoma, cervix. Uniform, small, oval, and elongated nuclei containing stippled chromatin and lacking nucleoli; scanty cytoplasm
64 144 Fig.l27. Endocervical stromal sarcoma. Malignant spindle cell tumour without specific features surrounding endocervical gland Fig.l2S. Adenofibroma, cervix. Polypoid growth composed of well differentiated fibrous tissue lined by bland epithelium
65 145 Fig Blue naevus, cervix. Elongated cells containing melanin pigment in cervical stroma Fig.l30. Endocervical glandular hyperplasia. Closely packed, hyperplastic endocervical glands forming a layer sharply demarcated from underlying stroma
66 146 Fig.131. Tunnel cluster, cervix. Rounded aggregate of closely packed, dilated endocervical glands Fig.132. Tunnel cluster, cervix. Sharply circumscribed aggregate of closely packed endocervical glands, some of which are small and hyperplastic and others of which are cystically dilated
67 147 Fig Microglandular hyperplasia, cervix. Polypoid nodule composed of small glands and solid proliferation of loosely arranged epithelial cells Fig Microglandular hyperplasia, cervix. Nodule composed of mostly small glands containing mucin and acute inflammatory cells
68 148 Fig.135. Arias-Stella change, cervix. Numerous endocervical glands with uniformly spaced fine papillae; patient was pregnant Fig.136. Arias-Stella change, cervix. Glands with regularly spaced papillae lined by hobnail type cells; higher magnification of Fig. 135
69 149 Fig Mesonephric remnants, cervix. Mesonephric duct with pseudopolypoid stromal projections into lumen and mesonephric tubules lined by cuboidal epithelium with colloid-like material in lumen Fig Mesonephric hyperplasia, cervix. Lobular arrangement of closely packed mesonephric tubules in cervical wall
70 150 Fig Mesonephric hyperplasia, cervix. Closely packed mesonephric tubules, some of which are cystic ally dilated, filled with colloid-like material Fig Mesonephric hyperplasia, cervix. Papillary hyperplasia of mesonephric duct
71 151 Fig Ciliated cell metaplasia, cervix. Gland lined by pseudostratified, ciliated epithelium Fig.142. Endometriosis, cervix. Endometrial type glands and stroma attached to endocervical mucosa; large focus of smooth muscle metaplasia of endometriotic stroma
72 152 Fig Ectopic decidua, cervix. Polypoid mass composed largely of stromal cells resembling decidual cells of the endometrium Fig Adenosls, vagina. Glands surrounded by inflammatory cells lying in the superficial lamina propria
73 153 Fig.145. Adenosis, vagina. Glands lined by mucinous epithelium Fig.l46. Adenosis, vagina. Tuboendometrial gland lined by ciliated epithelium
74 154 Fig.147. Adenosis, vagina. Glands and surface epithelium completely replaced by metaplastic squamous epithelium Fig Clear cell adenocarcinoma, vagina. Diffuse, clear cell pattern resembling that of renal cell carcinoma
75 155 Fig Clear cell adenocarcinoma, vagina. Tubular pattern with tubular structures lined by hobnail cells Fig. ISO. Clear cell adenocarcinoma, vagina. Cystic pattern
76 156 Fig.1S1. Rhabdomyoma, vagina. Large, mature striated muscle cells in fibrous stroma Fig.1S2. Sarcoma botryoides (embryonal rhabdomyosarcoma), vagina. Multiple polypoid projections composed of cellular tumour covered by squamous epithelium
77 157 Fig.lS3. Sarcoma botryoides (embryonal rhabdomyosarcoma), vagina. Superficial (cambium) layer of cellular tumour and subjacent layer of oedematous tumour Fig.lS4. Sarcoma botryoides (embryonal rhabdomyosarcoma), vagina. Rhabdomyoblasts
78 158 Fig. ISS. Mixed tumour, vagina. Epithelial component separated by stroma from overlying squamous epithelium Fig Mixed tumour, vagina. Nest of squamous cells adjacent to predominant small cells of stromal type
79 159 Fig.IS7. Malignant lymphoma, vagina. Solid mass of lymphoid cells situated mainly deep in vaginal wall Fig. ISS. Stromal polyp (pseudosarcoma botryoides), vagina. Stroma containing numerous large cells and dilated, thin-walled vessels
80 160 Fig.159. Stromal polyp (pseudosarcoma botryoides), vagina. Star-shaped cells, some of which are multinucleated, with pointed processes; absence of mitotic activity Fig Postoperative spindle cell nodule, vagina. Intersecting fascicles of closely packed spindle cells resembling sarcoma
81 161 Fig.161. Postoperative spindle cell nodule, vagina. Spindle cells with large nuclei; numerous mitotic figures Fig Prolapse of fallopian tube, vagina. Plicae expanded and fused with chronic inflammation and fibrosis of stroma
82 162 Fig.163. Vestibular squamous papilloma. Squamous epithelium without atypia lining delicate fibrovascular stalk Fig.164. Fibroepithelial polyp, vulva. Polypoid lesion with prominent fibrovascular core covered by hyperkeratotic squamous epithelium that lacks atypia
83 163 Fig Condyloma acuminatum, vulva. Multipolypoid lesion lined by thick squamous epithelium Fig Condyloma acuminatum, vulva. Focal, superficial, human papilloma-virus changes
84 164 Fig.167. Moderate dysplasia (VIN2). Disorderly arrangement of atypical cells in lower half of epithelium and maturation in upper half Fig Severe dysplasia (VIN3). Corps ronds with pyknotic nuclei surrounded by haloes; atypical nuclei in upper third of epithelium
85 165 Fig.169. Carcinoma in situ (VIN3). Crowded small cells without maturation occupying full thickness of epithelium Fig Carcinoma in situ (simplex type) (VIN3). Nuclear abnormalities with abortive pearl formation in papillary downgrowth of squamous epithelium
86 166 Fig.I71. Squamous cell carcinoma, vulva. Nests of malignant squamous cells, some of which are rounded and basaloid and others of which show squamous cell maturation Fig.I72. Squamous cell carcinoma, nonkeratinizing, vulva. Anastomosing trabeculae
87 167 Fig Squamous cell carcinoma, basaloid, vulva. Carcinoma cells resembling those of squamous carcinoma in situ of cervix Fig Verrucous carcinoma, vulva. Abundant keratin formation and bulbous downgrowths of well differentiated squamous epithelium
88 168 Fig.17S. Verrucous carcinoma, vulva. High degree of differentiation of tumour cells Fig Warty (condylomatous) carcinoma, vulva. Verrucous surface and underlying invasive carcinoma
89 169 Fig Warty (condylomatous) carcinoma, vulva. Noninvasive component with koilocytosis-iike changes ~Depthof invasion Fig.178. Method of measurement ofthickness and depth of invasion of squamous cell carcinoma of vulva
90 170.,. Fig.179. Squamous cell carcinoma, vulva. Tumour 5 mm in maximal vertical thickness Fig.ISO. Basal cell carcinoma, vulva. Anastomosing bands of malignant basal cells arising from base of squamous epithelium
91 171 Fig.ISI. Papillary hidradenoma, vulva. Cystic papillary tumour sharply demarcated from adjacent stroma Fig. IS2. Papillary hidradenoma, vulva. Slit-like and rounded glands with papillae; apocrine metaplasia of tumour cells (left)
92 172 Fig Papillary hidradenoma, vulva. Layer of myoepithelial cells subjacent to secretory cells Fig Paget disease, vulva. Large, rounded, pale Paget cells distributed within thickened squamous epithelium
93 173 Fig.18S. Paget disease, vulva. Paget cells with foamy cytoplasm, some of which have a signet ring appearance Fig.186. Paget disease, vulva. Associated invasive carcinoma
94 174 Fig.1S7. Bartholin gland adenocarcinoma. Papillary pattern Fig.1SS. Granular cell tumour, vulva. Replacement of dermis by tumour cells with overlying pseudo epitheliomatous hyperplasia
95 175 Fig Granular cell tumour, vulva. Coarse granules filling cytoplasm of tumour cells Fig.190. Aggressive angiomyxoma, vulva. Tumour composed of hypocellular, loose, myxoid tissue containing numerous blood vessels and invading fat (right)
96 176 Fig Aggressive angiomyxoma, vulva. Myxoid tissue containing blood vessels with slightly thickened walls Fig Dysplastic melanocytic naevus, vulva. Atypical naevus cells in papillary and reticular dermis
97 177 Fig.193. Malignant melanoma, vulva. Pigmented and nonpigmented spindle cells diffusely replacing upper dermis Fig Malignant melanoma, vulva. Large rounded cells with central nuclei and prominent nucleoli and with pigmented, abundant cytoplasm at junction of epidermis and dermis
98 178 Fig.195. Malignant melanoma, vulva. Spindle-shaped nuclei creating a resemblance to spindle cell sarcoma Fig.196. Langerhans cell histiocytosis, vulva. Diffuse proliferation of histiocytes with a few eosinophils (arrows)
99 179 Fig.197. Bartholin duct cyst. Cyst lined by mucinous and metaplastic squamous epithelium Fig.198. Epidermal cyst. Cyst filled with keratin and lined by thin layer of squamous epithelium
100 180 Fig Lichen sclerosus, vulva. Loss of rete ridges, homogeneous, parvicellular subepithelial layer and deep layer containing numerous round cells Fig Squamous cell hyperplasia, vulva. Acanthosis and hyperkeratosis without atypia and without features of specific forms of dermatosis or dermatitis
101 Subject Index Adenofibroma.... Adenoma, minor vestibular glands Adenoma, villous.... Adenomatoid tumour.... Adenomyoma.... atypical polypoid.... Adenomyosis.... Adenosarcoma.... heterologous.... homologous.... Adenosis.... atypical.... with dysplasia-carcinoma in situ Angiokeratoma.... Angiomyxoma, aggressive.... Arias-Stella change.... Atypia after radiation therapy.... glandular.... squamous.... Atypical polypoid adenomyoma.. Bartholin gland carcinoma.... adenocarcinoma.... adenoid cystic.... adenosquamous.... squamous cell.... transitional cell.... Bethesda system.... Blighted ovum.... Bone, retention of fetal.... Bowen disease.... Bowenoid papulosis.... Pages 23, ,61 23,49 23, ,24,49,60 24,49 24,49 56, ,51, ,14,43,57 40,55 23, ,56 34, Candida infection Carcinofibroma Carcinoid tumour... 47,58 Carcinoma adenoacanthoma ,16 Figures ,38 39,40 39, , ,191 57,58,135,136 5, , ,
102 182 Subject Index Carcinoma, adenocarcinoma.... argyrophil cell.... Bartholin gland.... ciliated cell.... clear cell.... ectopic cloacal.... endometrioid.... in situ.... mesonephric.... minimal deviation.... mixed.... mucinous.... endocervical type.... intestinal type.... papillary.... Bartholin gland.... clear cell.... endocervical.... endometrioid.... mucmous.... secretory.... serous.... Skene gland.... sweat gland.... villogiandular.... with squamous differentiation.... adenoid basal.... adenoid cystic.... adenoma malignum.... adenosquamous.... basal cell.... meta typical.... basosquamous.... breast, ectopic.... glassy cell.... grade, endometrial.... metastatic.... mucoepidermoid.... signet-ring cell.... small cell.... squamous cell acantholytic.... Bartholin gland.... Pages Figures 14-18,27,28,42,44-46,9-19, , 51,52,58,62,63, ,186, ,16,27,28,42,45 52,58, ,45, ,46,52, ,44,45,58,70 44,58 45,58 15,16,44,45, , , ,44, ,47,58,68 46,58, ,46,58, , ,16 26,45,50,56,61,75, , ,47,58 17,18,39-43,47,53, 56,65-68, , , , ,111 19, ,18,19,112,113, 115, , ,112, ,19,112,113, , , ,111 16,17, , ,107,
103 Subject Index 183 basaloid.... condylomatous.... in situ.... keratinizing.... lymphoepithelioma-like... microinvasive.... non-keratinizing.... papillary.... verrucous.... warty.... transitional cell.... undifferentiated.... giant cell.... large cell.... small cell.... spindle cell.... verrucous.... with choriocarcinoma.... Carcinosarcoma.... heterologous.... homologous.... Cartilage, metaplasia.... retention of fetal.... Cell argentaffin.... argyrophil.... foam.... Paneth.... Cervical intraepithelial neoplasia (CrN).... Change (see also metaplasia) Arias-Stella.... clear cell.... foam cell.... myxoid in leiomyoma.... in leiomyosarcoma.... papillary.... surface syncytial.... Chorioadenoma destruens.... Choriocarcinoma.... germ cell origin.... gestational.... with carcinoma.... CrN (cervical intraepithelial neoplasia).... Condyloma acuminatum.... giant (Buschke and Lowenstein).... Pages 67 42,56,67 39,40,43,47,56,65,66 42,56,66, ,42,47,53 42,47, ,18,42,56,67 42,56, ,47, ,47, ,18,42,56, ,49,60 24,49 24, ,44,45 18, ,44,47 28,51, ,29 19, , , ,44,47 39,55,64,65 67 Figures ,177 95,107,169, ,102,171, , , , , , , ,107 57,58,135, , ,166
104 184 Subject Index Condyloma, flat.... Crohn's disease.... Cyst Bartholin duct.... canal of Nuck cervical.... ciliated.... dermoid.... epidermal.... epithelial, myometrial.... Gartner duct.... mesonephric.... mesothelial.... mucinous.... mullerian.... myometrial, epithelial.... nabothian.... paraurethral.... wolffian duct.... Decidua, ectopic.... Deportation, villous.... Dermatitis, eczematous.... Dermatofibroma.... Dermatofibrosarcoma protuberans Dermoid cyst.... Desmoid tumour.... Dysplasia glandular.... squamous Endodermal sinus tumour.... Endolymphatic stromal myosis.. Endometrial stroma (see stroma) Endometriosis.... stromal.... Endometritis, chronic.... xanthogranulomatous.... Eosinophilic granuloma.... Erythroplasia of Queyrat Fallopian tube, prolapse Fasciitis, nodular.... Fibrolipoma.... Fibroma.... Fibromatosis (desmoid tumour) Fibrosis, subepidermal nodular. Germ cell tumours.... Glia, retention offetal.... Pages ,78 50,61 63, , ,78 51, , , ,40,47,56,65,66 25,50,60,75 18,19 53,63, , ,50,60,61,75 25,29,54 Figures ,167,168 22,
105 Subject Index 185 Pages Glioma... 25,29 Glomus tumour Granular cell tumour Granulation tissue, vaginal vault. 62 Figures , 189 Haemangioma.... acquired.... capillary.... cavernous.... sclerosing.... Hidradenoma clear cell.... papillary.... Histiocytoma benign fibrous.... malignant fibrous.... Histiocytosis, Langerhans cell (histiocytosis X).... HPV (human papilloma virus).. Hydatidiform mole complete.... mvaslve.... partial.... Hydropicabortus.... Hyperplasia endocervical glandular.... endometrial.... adenomatous.... atypical.... complex.... simple.... mesonephric.... microglandular.... pseudoepitheliomatous.... squamous cell , ,40,42,55,56, ,35 34, ,14 13,14 13,14 13,14 13,14 45,46,52 51, , ,6 3,4 1, , Infection, candida.... Inflammatory pseudo tumor Intravenous leiomyomatosis... Kaposi sarcoma.... Keratoacanthoma.... Koilocytosis.... Leiomyoblastoma.... Leiomyoma.... bizarre.... cellular.... clear cell.... epithelioid , ,41, ,20,21,47,59, , , ,29
106 186 SUbject Index Leiomyoma,lipoleiomyoma.. metastasizing.... pleomorphic.... plexiform.... symplastic.... uncertain malignant potential. Leiomyomatosis diffuse.... intravenous.... Leiomyosarcoma.... epithelioid.... myxoid.... Leukemia.... Lichen planus.... sclerosus.... simplex chronicus.... Lipogranuloma, sclerosing.... Lipoleiomyoma.... Lipoma.... Lymphangioma.... Lymphoepithelioma-like carcinoma Lymphoma, malignant.... Lymphoma-like lesions.... Pages ,21,47,59, ,50,61, ,71 22, ,30,50,61,75 30,54,63 Figures , Malakoplakia.... Malignant fibrous histiocytoma.... mesodermal mixed tumour... Melanoma, malignant.... Merkel cell tumour.... Mesonephric adenocarcinoma.... cyst.... hyperplasia.... remnants.... Metaplasia (see also change) adipocyte.... cartilaginous.... ciliated cell.... eosinophilic cell.... epidermal.... fatty (adipocyte).... hobnail cell.... intestinal.... morular.... mucinous.... endocervical-type.... intestinal-type ,49,60 50,61, ,46,52,58 63,78 45,46, , , , , , ,
107 oncocytic osseous.... smooth muscle.... squamous.... stromal.... transitional.... tubal.... Microglandular hyperplasia Mixed tumour (see tumour) Naevus blue lipomatosus superficialis.... melanocytic.... acquired.... congenital.... dysplastic.... Neurilemoma (schwannoma)... Neurofibroma.... Neuroma, traumatic (amputation) Paget disease.... Papilloma mullerian.... squamous.... Placental site exaggerated.... nodule and plaque.... trophoblastic tumour.... Plexiform leiomyoma.... Polyp endocervical.... endometrial.... fibroepithelial.... stromal.... Postoperative spindle cell nodule. Prolapse, fallopian tube.... Psammoma bodies.... Pseudo epitheliomatous hyperplasia.... Pseudo sarcoma botryoides (stromal polyp).... Pseudotumor, inflammatory.... Psoriasis.... Pyogenic granuloma.... Radiation therapy atypia.... Remnants, mesonephric.... Pages ,28,29 26,39,40,57,78 28,29 40, ,63 50,60, ,60,74, ,57 39,55, ,53 36, ,62 31, 54, , ,62 30, Subject Index 187 Figures ,50,88,147, , ,163 83,84 85, , , , ,
108 188 Subject Index Rhabdoid tumour, malignant... Rhabdomyoma.... Pages 73 59,72 Figures 151 Sarcoma (see also tumour) alveolar soft-part.... angiosarcoma.... botryoides.... chondrosarcoma.... dermatofibrosarcoma protuberans 73 endocervical stromal endometrial stromal.... high grade.... low grade.... endometrioid stromal.... Kaposi.... leiomyosarcoma.... liposarcoma.... malignant fibrous histiocytoma nerve sheath tumours, malignant osteosarcoma.... rhabdomyosarcoma.... secondary.... Schwannoma (neurilemoma)... Seborrheic keratosis.... Sex cord-like tumors.... SIL (squamous intraepithelial lesions).... Smooth muscle metaplasia.... tumour of uncertain malignant potential.... Spindle cell nodule, postoperative Squamous intraepitheliallesions (see SIL) Stroma endocervical stromal sarcoma.. 47 endometrial stromal nodule.... stromal sarcoma.... stromal tumour, mixed.... endometrioid stromal sarcoma endometriosis, stromal.... polyp, stromal.... Syringoma , ,48,59, ,19,53 18,19 18,19,53 48, ,21,47,59,73 22, ,48,59,73 48,59, ,56,65,66 18,28, ,54, ,19,48,53, ,53,59 48,53 53, ,23 32, , , , , ,159 Teratomas.... mature cystic (dermoid cyst).. Trichilemmoma.... Trichoepithelioma ,50,61 50,
109 Subject Index 189 Pages Trophoblastic lesions, unclassified 38 Tumour (see also carcinoma, sarcoma) adenomatoid... 22,61 carcinoid... 47,58 desmoid (fibromatosis) ectopic mammary tissue.... germ cell.... glial.... glomus.... granular cell.... malignant rhabdoid.... Merkel cell.... metastatic (see Tumour, secondary) mixed adenofibroma adenomyoma adenosarcoma carcinofibroma.... endometrial stromal and malignant mesodermal.... smooth muscle.... synovial sarcoma-like.... vaginal.... nerve sheath, malignant.... neuroectodermal.... plexiform leiomyoma.... secondary.... sex cord-like.... soft tissue.... heterologous.... homologous.... Wilms.... Yolk sac.... Tumouriet, plexiform.... Tunnel cluster ,50,60,61,75 25, ,49 23,49 23,24,49, ,49, ,45,48,50,56, 59-61,75, ,48,60, ,50, 60, Figures 37, , ,40 41, , , , ,132 VAIN (vaginal intraepithelial neoplasia).... Villous deportation.... VIN (vulvar intraepithelial neoplasia).... Wilms tumour.... Xanthogranuloma, benign.... Xanthoma, verruciform.... Yolk sac tumour , ,50,60,
Normal endometrium: A, proliferative. B, secretory.
Normal endometrium: A, proliferative. B, secretory. Nội mạc tử cung Nội mạc tử cung Cyclic changes in endometrium.. Approximate relationship of useful microscopic changes. Arias-Stella reaction in endometrial
More informationDr Sanjiv Manek Oxford. Oxford Pathology Course 2010 for FRCPath Illustration-Cellular Pathology. Oxford Radcliffe NHS Trust
Dr Sanjiv Manek Oxford Oxford Pathology Course 2010 for FRCPath Illustration-Cellular Pathology. Oxford Radcliffe NHS Trust Ovarian Endometrial Vulvo-vaginal Cervical Illustration-Cellular Pathology. Oxford
More informationVulva Inflammatory Disorders Lichen Planus Fixed Drug Eruption Erythema Multiforme Plasmacytosis Mucosae (Zoon) Lichen Sclerosus Allergic Contact
Vulva Inflammatory Disorders Lichen Planus Fixed Drug Eruption Erythema Multiforme Plasmacytosis Mucosae (Zoon) Lichen Sclerosus Allergic Contact Dermatitis Psoriasis Lichen Simplex Chronicus Foreign Body
More information6/5/2010. Outline of Talk. Endometrial Alterations That Mimic Cancer & Vice Versa: Metaplastic / reactive changes. Problems in Biopsies/Curettages
Outline of Talk Endometrial Alterations That Mimic Cancer & Vice Versa: Problems in Biopsies/Curettages Metaplastic / reactive changes Mucinous change Microglandular hyperplasia-like change Squamous metaplasia
More informationGross appearance of nodular hyperplasia in material obtained from suprapubic prostatectomy. Note the multinodular appearance and the admixture of
Tiền liệt tuyến Tiền liệt tuyến Gross appearance of nodular hyperplasia in material obtained from suprapubic prostatectomy. Note the multinodular appearance and the admixture of solid and microcystic areas.
More informationPathology Slides. [Pathology]
Pathology Slides MedicoNotes provides real laboratory pathological slides to aid you to differentiate between different pathological structures under microscope. www.mediconotes.com Histology slides example
More informationCINtec p16 INK4a Staining Atlas
CINtec p16 INK4a Staining Atlas Rating Rating Positive The rating positive will be assigned if the p16 INK4a -stained slide shows a continuous staining of cells of the basal and parabasal cell layers of
More informationMody. AIS vs. Invasive Adenocarcinoma of the Cervix
Common Problems in Gynecologic Pathology Michael T. Deavers, M.D. Houston Methodist Hospital, Houston, Texas Common Problems in Gynecologic Pathology Adenocarcinoma in-situ (AIS) of the Cervix vs. Invasive
More informationPathology of the female genital tract
Pathology of the female genital tract Common illnesses of the female genital tract Before menarche Developmental anomalies Tumors (ovarial teratoma) Amenorrhea Fertile years PCOS, ovarian cysts Endometriosis
More informationPrepared By Jocelyn Palao and Layla Faqih
Prepared By Jocelyn Palao and Layla Faqih The structure of the suspected atypical cell should always be compared to the structure of other similar, benign, cells which are present in the smears. The diagnosis
More informationBenign and malignant epithelial lesions: Seborrheic keratosis: A common benign pigmented epidermal tumor occur in middle-aged or older persons more
Benign and malignant epithelial lesions: Seborrheic keratosis: A common benign pigmented epidermal tumor occur in middle-aged or older persons more common on the trunk; but extremities, head and neck are
More informationVULVAR CARCINOMA. Page 1 of 5
VULVAR CARCINOMA EXAMPLE OF A VULVAR CARCINOMA USING PROPOSED TEMPLATE Case: Invasive squamous cell carcinoma arising in D-VIN Tumor in left labia major Left partial vaginectomy and sentinel lymph node
More informationEndometrial pathology. Dr Tom Dodd and Dr Georgina England
Endometrial pathology Dr Tom Dodd and Dr Georgina England Case 1 Female age 35 Case 1 Proliferative endometrium Case 2 Female age 38 Case 2 Secretory endometrium Dating endometrium Assessed on the
More informationDiagnostically Challenging Cases in Gynecologic Pathology
Diagnostically Challenging Cases in Gynecologic Pathology Eric C. Huang, M.D., Ph.D. Department of Pathology and Laboratory Medicine University of California, Davis Medical Center Case 1 Presentation 38
More informationS2199 S2200. * Speaker's diagnosis 78
98 21 2 14 13:30 * Speaker's diagnosis 78 S2199 Meningioma 48 Papillary meningioma * 30 Angiomatous meningioma 15 Ependymoma 12 Papillary ependymoma 6 Anaplastic ependymoma 2 Cellular ependymoma 1 Hemangioblastoma
More informationDiseases of the vulva
Diseases of the vulva 1. Bartholin Cyst - Infection of the Bartholin gland produces an acute inflammation within the gland (adenitis) and may result in an abscess. Bartholin duct cysts - Are relatively
More informationTinh hoàn
Tinh hoàn Tinh hoàn Tinh hoàn Tiền liệt tuyến Tiền liệt tuyến Mào tinh hoàn Mào tinh hoàn Túi tinh Túi tinh Túi tinh Túi tinh So-called cystadenoma of seminal vesicle. Gross appearance of granulomatous
More informationGynecologic Cytopathology: Glandular lesions
Gynecologic Cytopathology: Glandular lesions Lin Wai Fung (MSc, MPH, CMIAC) 17/4/2014 Glandular lesions of the uterus Endocervix Endometrium Normal endocervical cells Sheets, strips well-preserved architecture:
More informationCase year female. Routine Pap smear
Case 1 57 year female Routine Pap smear Diagnosis? 1. Atypical glandular cells of unknown significance (AGUS) 2. Endocervical AIS 3. Endocervical adenocarcinoma 4. Endometrial adenocarcinoma 5. Adenocarcinoma
More informationDisclosure. Case. Mixed Tumors of the Uterine Corpus and Cervix. I have nothing to disclose
Mixed Tumors of the Uterine Corpus and Cervix Marisa R. Nucci, M.D. Division of Women s and Perinatal Pathology Department of Pathology Brigham and Women s Hospital Boston, MA UCSF Current Issues in Anatomic
More informationGynaecological Malignancies
Gynaecological Malignancies Dr Rodney Itaki Lecturer Anatomical Pathology Discipline University of Papua New Guinea Division of Pathology School of Medicine & Health Sciences Overview Genital tract tumors
More informationEffective January 1, 2018 ICD O 3 codes, behaviors and terms are site specific
Effective January 1, 2018 codes, behaviors and terms are site specific /N 8551/3 Acinar adenocarcinoma (C34. _) Lung primaries diagnosed prior to 1/1/2018 use code 8550/3 For prostate (all years) see 8140/3
More informationEffective January 1, 2018 ICD O 3 codes, behaviors and terms are site specific
Effective January 1, 2018 codes, behaviors and terms are site specific Status /N 8010/3 Urachal carcinoma (C65.9, C66.9, C67. _, C68._) 8013/3 Combined large cell neuroendocrine carcinoma (C34. _, C37.9)
More informationGross appearance of peritoneal cysts. They have a thin, translucent wall and contain a clear fluid.
Gross appearance of peritoneal cysts. They have a thin, translucent wall and contain a clear fluid. So-called multicystic benign mesothelioma. A, Gross appearance. So-called multicystic benign mesothelioma.
More informationICD-O Morphology code. R=Rare Tier Tumour ICD-O Topography code C30.0, C31
R=Rare Tier Tumour ICD-O Topography code ICD-O Morphology code EPITHELIAL TUMOURS OF NASAL CAVITY AND SINUSES R 2 Squamous cell carcinoma with variants of nasal cavity and sinuses C30.0, C3 C30.0, C3 8000,
More information2018 ICD-O-3 Updates in Table Format with Annotation for Reference
Status Histology Description (this may be preferred term or a synonym) Report Comments New term 8010 3 Urachal carcinoma (C65.9, C66.9, C67._, C68._) New term 8013 3 Combined large cell neuroendocrine
More informationDemystifying Endometrial Hyperplasia
Demystifying Endometrial Hyperplasia A review from Diagnostic Histopathology 19:7 Dr R Hadden ST5 Histopathology Derriford Hospital Plymouth Endometrium Target for sex-steroid hormones Glands Stroma Proliferate
More informationMay 2017 TSL workshops. EQA 012 Final analysis with Diagnoses
May 2017 TSL workshops EQA 012 Final analysis with Diagnoses CASE 1 28 yr old female with menorrhagia. Well diff endometrioid adenocarcinoma (back ground complex hyperplasia) 4 Non-atypical endometrial
More informationSalivary Glands 3/7/2017
Salivary Glands 3/7/2017 Goals and objectives Focus on the entities unique to H&N Common board type facts Information for your future practice Salivary Glands Salivary Glands Major gland. Paratid. Submandibular.
More informationAnnual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology
bs_bs_banner doi:10.1111/jog.12596 J. Obstet. Gynaecol. Res. Vol. 41, No. 2: 167 177, February 2015 Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology
More informationA neoplasm is defined as "an abnormal tissue proliferation, which exceeds that of adjacent normal tissue. This proliferation continues even after
NEOPLASIA Neoplasia is a very important topic in pathology because neoplasms are both common and serious diseases. A neoplasm literally means a new growth, and this term is used interchangeably with a
More informationWhen Immunostains Can Get You in Trouble: Gynecologic Pathology p16: Panacea or Pandora s Box?
When Immunostains Can Get You in Trouble: Gynecologic Pathology p16: Panacea or Pandora s Box? Teri A. Longacre, MD Stanford Medicine Stanford California pi6 in Gynecologic Pathology: Panacea or Pandora
More informationMalignant Peripheral Nerve Sheath Tumor
C H A P T E R 120 Malignant Peripheral Nerve Sheath Tumor Currently, malignant peripheral nerve sheath tumor (MPNST) is the most commonly used generic name for the neoplasms known in the past as neurosarcoma,
More informationHistopathology: Cervical HPV and neoplasia
Histopathology: Cervical HPV and neoplasia These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need to learn about
More informationPapillary Lesions of the breast
Papillary Lesions of the breast Emad Rakha Professor of Breast Pathology The University of Nottingham Papillary lesions of the breast are a heterogeneous group of disease, which are characterised by neoplastic
More informationEndometrial Metaplasia, Hyperplasia & Other Cancer Mimics: a Consultant s Experience
Endometrial Metaplasia, Hyperplasia & Other Cancer Mimics: a Consultant s Experience Pacific Northwest Society of Pathologists Vancouver, B.C. September 26, 2015 Teri A. Longacre, M.D. longacre@stanford.edu
More informationClinically Microscopically Pathogenesis: autoimmune not lifetime
Vulvar Diseases: Can be divided to non-neoplastic and neoplastic diseases. The neoplastic diseases are much less common. Of those, squamous cell carcinoma is the most common. most common in postmenopausal
More informationNote: The cause of testicular neoplasms remains unknown
- In the 15- to 34-year-old age group, they are the most common tumors of men. - Tumors of the testis are a heterogeneous group of neoplasms that include: I. Germ cell tumors : 95%; all are malignant.
More informationPathology of the skin. 2nd Department of Pathology, Semmelweis University
Pathology of the skin 2nd Department of Pathology, Semmelweis University Histology of the skin Epidermis: Stratum corneum Stratum granulosum Stratum spinosum Stratum basale Dermis: papillary and reticular
More informationLGM International, Inc.
Liqui-PREP TM Cytology Atlas Preface The following pictures are examples with descriptions of cytology slides processed with the Liqui-PREP TM System.. The descriptions are reviewed by Pathologists. It
More informationSalivary Gland Cytology
Salivary Gland Cytology Diagnostic challenges and potential pitfalls Tarik M. Elsheikh, MD Professor and Medical Director Anatomic Pathology Cleveland Clinic FNA Salivary Gland Lesions Indications Distinguish
More informationPage # 1. Endometrium. Cellular Components. Anatomical Regions. Management of SIL Thomas C. Wright, Jr. Most common diseases:
Endometrium Pathology of the Endometrium Thomas C. Wright Columbia University, New York, NY Most common diseases: Abnormal uterine bleeding Inflammatory conditions Benign neoplasms Endometrial cancer Anatomical
More informationDepartment of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland.
UTERINE ADENOSARCOMA W Glenn McCluggage Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland. Definition of Adenosarcoma: A mixed tumor composed of benign neoplastic glandular
More informationIndex. Cytoplasm, nonepithelial malignant tumor features 70
Accurette device 23 Adenosarcoma, differential diagnosis 80, 81 Arias-Stella reaction 65 Atypical endocervical cells 8 Atypical endometrial cells 8 Atypical glandular cells (AGC) 8, 9 Atypical glandular
More informationMVST BOD & NST PART IB Thurs. 2 nd & Fri. 3 rd March 2017 Pathology Practical Class 23
MVST BOD & NST PART IB Thurs. 2 nd & Fri. 3 rd March 2017 Pathology Practical Class 23 Neoplasia I Neoplasia I: Benign and malignant neoplasms in glandular epithelium and mesenchyme 1.0. Aims 1. To understand
More informationCLINICAL SIGNIFICANCE OF BENIGN EPITHELIAL CHANGES
Papillomas. Papillomas are composed of multiple branching fibrovascular cores, each having a connective tissue axis lined by luminal and myoepithelial cells ( Fig. 23-11 ). Growth occurs within a dilated
More informationBasal cell carcinoma 5/28/2011
Goal of this Presentation A practical approach to the diagnosis of cutaneous carcinomas and their mimics Thaddeus Mully, MD University of California San Francisco To review common non-melanoma skin cancers
More informationDifferential Diagnosis of Oral Masses. Palatal Lesions
Differential Diagnosis of Oral Masses Palatal Lesions Palatal Masses Periapical Abscess Torus Palatinus Mucocele Lymphoid Hyperplasia Adenomatous Hyperplasia Benign Salivary Neoplasms Malignant Salivary
More informationDisorders of Cell Growth & Neoplasia. Histopathology Lab
Disorders of Cell Growth & Neoplasia Histopathology Lab Paul Hanna April 2010 Case #84 Clinical History: 5 yr-old, West Highland White terrier. skin mass from axillary region. has been present for the
More informationPATHOLOGY OF THE FEMALE GENITAL TRACT
MBBS 2 nd Yr. Lecture Dr. Annie Cheung September 30, 2002 9:30 am LT2,G/F, Academic and Administration Block Faculty of Medicine Building UROGENITAL SYSTEM PATHOLOGY OF THE FEMALE GENITAL TRACT Learning
More informationThey Do Look Alike : Mimics of Prostate Cancer in Biopsy Samples
They Do Look Alike : in Biopsy Samples Gladell P. Paner, MD Departments of Pathology and Surgery (Urology) University of Chicago, IL USA Gladell.paner@uchospitals.edu Benign in Needle Biopsy 1. Benign
More informationnumber Done by Corrected by Doctor Maha Shomaf
number 16 Done by Waseem Abo-Obeida Corrected by Zeina Assaf Doctor Maha Shomaf MALIGNANT NEOPLASMS The four fundamental features by which benign and malignant tumors can be distinguished are: 1- differentiation
More informationSUPPLEMENTARY FIG. S2. Teratoma. Portion of a teratoma composed of neural tissue. The large cells in the central part correspond to ganglion cells.
Supplementary Data SUPPLEMENTARY FIG. S1. Teratoma. The tumor is composed predominantly of keratinizing squamous epithelium (Sq), which forms cysts filled with keratin (arrows). The tumor also contains
More informationObjectives. Atypical Glandular Cells. Atypical Endocervical Cells. Reactive Endocervical Cells
2013 California Society of Pathologists 66 th Annual Meeting San Francisco, CA Atypical Glandular Cells to Early Invasive Adenocarcinoma: Cervical Cytology and Histology Christina S. Kong, MD Associate
More informationDiagnostic Cytology of Cancer Cases
Diagnostic Cytology of Cancer Cases Somporn Techangamsuwan Companion Animal Cancer Research Unit (CAC-RU) Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University 1 Tumor or Non-tumor
More informationEpithelial tumors. Dr. F.F. Khuzin, PhD Dr. M.O. Mavlikeev
Epithelial tumors Dr. F.F. Khuzin, PhD Dr. M.O. Mavlikeev Epithelial tumors Tumors from the epithelium are the most frequent among tumors. There are 2 group features of these tumors: The presence in most
More information2 Berkeley Street, Suite 403, Toronto, Ontario M5A 2W3 Visit us at: Tel: Fax:
E-Path A.I. Engine Knowledge Base Enhancements Version 1.0.0.29 April 1, 2018 The major enhancements in the E-Path Knowledge Base from versions 1.0.0.28 through 1.0.0.29 are as follows: 1. Addition/modification
More informationDiseases of the breast (1 of 2)
Diseases of the breast (1 of 2) Introduction A histology introduction Normal ducts and lobules of the breast are lined by two layers of cells a layer of luminal cells overlying a second layer of myoepithelial
More informationSESSION 1: GENERAL (BASIC) PATHOLOGY CONCEPTS Thursday, October 16, :30am - 11:30am FACULTY COPY
SESSION 1: GENERAL (BASIC) PATHOLOGY CONCEPTS Thursday, October 16, 2008 9:30am - 11:30am FACULTY COPY GOAL: Describe the basic morphologic (structural) changes which occur in various pathologic conditions.
More information2/9/2015. Bartholin Cyst. Vulva: Squamous epithelium skin. Vagina: Squamous epithelium mucosa. Cervix: Ectocervix: squamous Endocervix: glandular
Vulva: Squamous epithelium skin Bartholin Cyst Vagina: Squamous epithelium mucosa Cervix: Ectocervix: squamous Endocervix: glandular Slide courtesy of Dr. Lodge Rigal Slide courtesy of Dr. Lodge Rigal
More informationProliferative Epithelial lesions of the Breast. Sami Shousha, MD, FRCPath Charing Cross Hospital & Imperial College, London
Proliferative Epithelial lesions of the Breast Sami Shousha, MD, FRCPath Charing Cross Hospital & Imperial College, London Amman, November2013 Proliferative Epithelial Lesions of the Breast Usual type
More informationCytology and Surgical Pathology of Gynecologic Neoplasms
Cytology and Surgical Pathology of Gynecologic Neoplasms Current Clinical Pathology ANTONIO GIORDANO, MD, PHD SERIES EDITOR For further titles published in this series, go to http://www.springer.com/springer/series/7632
More informationHistopathology: skin pathology
Histopathology: skin pathology These presentations are to help you identify, and to test yourself on identifying, basic histopathological features. They do not contain the additional factual information
More informationAppendix I. A Summary of Common Pitfalls in Diagnostic Gynecologic and Obstetric Pathology
Appendix I. A Summary of Common Pitfalls in Diagnostic Gynecologic and Obstetric Pathology Section Chapter Mistaken for Comments Candidiasis A premalignant lesion (VIN) Chronically rubbed skin can produce
More informationBreast pathology. 2nd Department of Pathology Semmelweis University
Breast pathology 2nd Department of Pathology Semmelweis University Breast pathology - Summary - Benign lesions - Acute mastitis - Plasma cell mastitis / duct ectasia - Fat necrosis - Fibrocystic change/
More informationENODMETRIAL CARCINOMA: SPECIAL & NOT SO SPECIAL VARIANTS
ENODMETRIAL CARCINOMA: SPECIAL & NOT SO SPECIAL VARIANTS Pacific Northwest Society of Pathologists Vancouver, B.C. September 26, 2015 Teri A. Longacre, M.D. longacre@stanford.edu Stanford University, Stanford,
More informationNEOPLASIA-I CANCER. Nam Deuk Kim, Ph.D.
NEOPLASIA-I CANCER Nam Deuk Kim, Ph.D. 1 2 Tumor in the hieroglyphics of the Edwin Smith papyrus (1,600 B.C., Breasted s translation 1930) 3 War on Cancer (National Cancer Act, 1971) 4 Cancer Acts in Korea
More informationIn situ and Invasive Endocervical Carcinoma: Problems and Pitfalls in Diagnosis
In situ and Invasive Endocervical Carcinoma: Problems and Pitfalls in Diagnosis Rouba Ali-Fehmi,MD The Karmanos Cancer Institute, Wayne State University School of Medicine Global incidence of cervical
More informationAtypical Hyperplasia/EIN
EIN Atypical Hyperplasia/EIN Based on scientific and diagnostic advances, in 2014 the WHO moved that the precursor lesion for endometrioid carcinoma be atypical hyperplasia/ein, rather than what was previously
More informationPancreatitis: A Potential Pitfall in Endoscopic Ultrasound Guided Pancreatic FNA
Pancreatitis: A Potential Pitfall in Endoscopic Ultrasound Guided Pancreatic FNA Jack Yang, MD Department of Pathology, Medical University of South Carolina Objectives Understand the indication of EUS
More information1 NORMAL HISTOLOGY AND METAPLASIAS
1 NORMAL HISTOLOGY AND METAPLASIAS, MD Anatomy and Histology 1 Metaplasias 2 ANATOMY AND HISTOLOGY The female breast is composed of a branching duct system, which begins at the nipple with the major lactiferous
More informationSynonyms. Nephrogenic metaplasia Mesonephric adenoma
Nephrogenic Adenoma Synonyms Nephrogenic metaplasia Mesonephric adenoma Definition Benign epithelial lesion of urinary tract with tubular, glandular, papillary growth pattern Most frequently in the urinary
More informationEpithelium. Four primary tissue types:
Epithelium Four primary tissue types: Epithelial (covering) Connective (support) Nervous (control) Muscular (movement) Smooth muscle Cardiac muscle Skeletal muscle 1 Epithelial Tissue Features Epithelial
More informationProblems in the Differential Diagnosis of Endometrial Hyperplasia and Carcinoma
THE 1999 LONG COURSE ON PATHOLOGY OF THE UTERINE CORPUS AND CERVIX Problems in the Differential Diagnosis of Endometrial Hyperplasia and Carcinoma Steven G. Silverberg, M.D. Department of Pathology, University
More informationOther Sites. Table 2 Continued. MPH Rules 11/8/07. NAACCR Webinar Series 1
MPH s 11/8/07 Other s 1 Table 2 Continued Use this two-page table to select combination histology codes. Compare the terms in the diagnosis to the terms in Columns 1 and 2. If the terms match, code the
More informationPRACTICAL ROADMAP EPITHELIUM A. JOVANOVIĆ
PRACTICAL ROADMAP EPITHELIUM A. JOVANOVIĆ Epithelia Simple epithelia Stratified epithelia Simple squamous Simple cuboidal Simple columnar Pseudostratified Stratified squamous - non keratinized - keratinized
More informationNotice of Faculty Disclosure
Mesenchymal Tumors of the Vulva: Old, New, Something(s) Different Napa Valley Conference Pathology Education Partners Inc May 15, 2018 Teri A. Longacre, M.D. longacre@stanford.edu Stanford University,
More informationTrophoblastic tumors
Trophoblastic tumors Uterus tumor course Oslo, 21-22/1/16 Prof. Ben Davidson, MD PhD Department of Pathology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway Cases 45 38 39 4 Case 45
More information64 YO lady THBSO for prolapse At gross : A 3 cm endometrial polyp in the fundus
Case 6 64 YO lady THBSO for prolapse At gross : A 3 cm endometrial polyp in the fundus Numerous irregular, large glands with leaf-like pattern Large glands with broad-based papillary infolding into the
More information04/09/2018. Squamous Cell Neoplasia and Precursor Lesions. Agenda. Squamous Dysplasia. Squamo-proliferative lesions. Architectural features
Squamous Cell Neoplasia and Precursor Lesions Jennifer L. Hunt, MD, MEd Aubrey J. Hough Jr, MD, Endowed Professor of Pathology Chair of Pathology and Laboratory Medicine University of Arkansas for Medical
More informationCondyloma Acuminatum. Mimics of Bladder Cancer. Squamous Papilloma. Squamous epithelium in bladder
Mimics of Bladder Cancer Murali Varma Cardiff, UK wptmv@cf.ac.uk Squamous epithelium in bladder Non-keratinising vaginal type mucosa common in trigone region in women Normal variant Sarajevo Nov 2013 Squamous
More informationAtlas of Eyelid and Conjunctival Tumors
Atlas of Eyelid and Conjunctival Tumors Jerry A. Shields, M.D. Director, Ocular Oncology Service Wills Eye Hospital Professor of Ophthalmology Thomas Jefferson University Philadelphia, Pennsylvania Carol
More informationLesions Mimicking Adenoid Cystic Carcinoma. Diagnostic Problems in Salivary Gland Pathology An Update 5/29/2009
Diagnostic Problems in Salivary Gland Pathology An Update Lesions Mimicking Adenoid Cystic Carcinoma Stacey E. Mills, M.D. W.S. Royster Professor of Pathology Director of Surgical and Cytopathology University
More informationCYSTIC TUMORS OF THE KIDNEY JOHN N. EBLE, M.D. CYSTIC NEPHROMA
Page 1 CYSTIC TUMORS OF THE KIDNEY JOHN N. EBLE, M.D. Department of Pathology & Laboratory Medicine Phone (317) 274-4806 Medical Science A-128 FAX: (317) 278-2018 635 Barnhill Drive jeble @iupui.edu Indianapolis,
More informationDiagnostic difficulties with lesions of the oral mucosa
BDIAP London, November 2010 School of Clinical Dentistry University of Sheffield Diagnostic difficulties with lesions of the oral mucosa Paul M Speight Dept Oral & Maxillofacial Pathology University of
More informationThe incidence of cervical adenocarcinoma (ADC) has
Cervical Adenocarcinoma of Human Papillomavirus Positive and Human Papillomavirus Negative Tumors Edyta C. Pirog, MD, PhD Context. Cervical adenocarcinomas span a diverse group of tumors with several distinct
More information05/07/2018. Types of challenges. Challenging cases in uterine pathology. Case 1 ` 65 year old female Post menopausal bleeding Uterine Polyp
Types of challenges Challenging cases in uterine pathology Nafisa Wilkinson Gynaecological Pathologist UCLH London Lack of complete history often, NO clinical history at all! Cases from other centres often
More informationCASE 4 21/07/2017. Ectopic Prostatic Tissue in Cervix. Female 31. LLETZ for borderline nuclear abnormalities
Female 31 CASE 4 LLETZ for borderline nuclear abnormalities PSA Ectopic Prostatic Tissue in Cervix AJSP 2006;30;209-215 usually incidental microscopic finding usually in ectocervical stroma? developmental
More informationEndometrial Stromal Tumors
Endometrial Stromal Tumors WHO Categories: Endometrial Stromal Nodule (ESN) Endometrial Stromal Sarcoma, low grade (LGESS) Endometrial Stromal Sarcoma, high grade (HGESS) Undifferentiated Uterine Sarcoma
More informationOutline 11/2/2017. Pancreatic EUS-FNA general aspects. Cytomorphologic features of solid neoplasms/lesions of the pancreas
ENDOSCOPIC ULTRASOUND GUIDED-FINE NEEDLE ASPIRATION CYTOLOGY OF PANCREAS Khalid Amin M.D. Assistant Professor Department of Laboratory Medicine and Pathology University of Minnesota Outline Pancreatic
More informationPancreas. Atrophy, acinar cell. Pathogenesis: Diagnostic key features:
Pancreas Atrophy, acinar cell Pathogenesis: Decrease in number and/or size of acinar cells may be due to spontaneous or experimentally induced degenerative changes, apoptosis, or a sequel of chronic inflammation.
More informationKeratinocyte tumors. Actinic Keratosis. Squamous cell carcinoma in situ. Squamous Cell Carcinoma. (aka Bowen s disease)
Actinic Keratosis Keratinocyte tumors Prepared by Kurt Schaberg Precancerous, risk of malignancy ~8-20% per year (progresses to SCC); Due to chronic sun exposure Rough scaly plaque; typically due to sun
More informationBiliary tract tumors
Short Course 2010 Annual Fall Meeting of the Korean Society for Pathologists Biliary tract tumors Joon Hyuk Choi, M.D., Ph.D. Professor, Department of Pathology, Yeungnam Univ. College of Medicine, Daegu,
More informationNeoplasia 2018 Lecture 2. Dr Heyam Awad MD, FRCPath
Neoplasia 2018 Lecture 2 Dr Heyam Awad MD, FRCPath ILOS 1. List the differences between benign and malignant tumors. 2. Recognize the histological features of malignancy. 3. Define dysplasia and understand
More informationDesmoplastic Melanoma R/O BCC. Clinical Information. 74 y.o. man with lesion on left side of neck r/o BCC
R/O BCC Sabine Kohler, M.D. Professor of Pathology and Dermatology Dermatopathology Service Stanford University School of Medicine Clinical Information 74 y.o. man with lesion on left side of neck r/o
More informationMacro- and microacinar proliferations of the prostate
Macro- and microacinar proliferations of the prostate (with emphasis on cancer mimics) Rodolfo Montironi, MD (IT), FRCPath (UK), IFCAP (USA) Polytechnic University of Marche Region (Ancona) School of Medicine,
More informationMULLERIAN PAPILLOMA ENTITY RECOGNITION FAILURE 04/04/2016 OUT OF SIGHT, OUT OF MIND: LESSER KNOWN LESIONS OF THE VULVOVAGINAL TRACT
OUT OF SIGHT, OUT OF MIND: LESSER KNOWN LESIONS OF THE VULVOVAGINAL TRACT 23 rd ANNUAL SEMINAR IN PATHOLOGY 30 APRIL 2016 W. Dwayne Lawrence MD MSc (Path.) Chief of Pathology and Laboratory Medicine Women
More informationXIII. Tumours of the liver and biliary system
XIII. Tumours of the liver and biliary system V. PONOMARKOV 1 & L. J. MACKEY 2 In this histological classification of liver and gall bladder tumours the tumour types largely correspond to those found in
More informationDUSTURBANCES OF GROWTH. MLS Basic histological diagnosis MLS HIST 422 Semester 8- batch 7 L8 Uz: Musa
DUSTURBANCES OF GROWTH MLS Basic histological diagnosis MLS HIST 422 Semester 8- batch 7 L8 Uz: Musa Agnesia: means complete absence of an organ (Kidney). Aplasia: s defined in general as "defective development
More informationXX. Tumours of the nasal cavity *
XX. Tumours of the nasal cavity * H. STONZI 1 & B. HAUSER2 Tumours of the nasal cavity are rare in domestic animals, most cases occurring in the dog. Epithelial tumours are the most common type in carnivores
More information