CURRICULUM VITAE HEGE H. DIVON PERSONAL DATA CURRENT POSITION

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CURRICULUM VITAE HEGE H. DIVON PERSONAL DATA Date of birth: 6 th of July 1974 Citizenship: Norwegian Two children Mobile: +47 47333817, email: hege.divon@vetinst.

1 CURRICULUM VITAE HEGE H. DIVON PERSONAL DATA Date of birth: 6 th of July 1974 Citizenship: Norwegian Two children Mobile: , hege.divon@vetinst.no CURRENT POSITION I am since October 2012 employed in a permanent position as senior scientist at the Norwegian Veterinary Institute, currently in the newly established Toxinology Research group. My area of expertise is molecular mycology with focus on mycotoxin-producing fungi and Fusarium head blight research, for the sake of ensuring food and feed safety and animal health. I am since 2014 leading the Strategic Institute Program, FUNtox, receiving annually 3,5 mill. kroner for research on Fungi and mycotoxins in a One Health perspective. The group is dynamic and interdisciplinary, involving scientists within various fields of research at the NVI (e.g. mycology, chemistry, toxicology, immunology, pathology). FUNDED NETWORKS AND RESEARCH PROJECTS 2018: Project leader of OBTAIN; A pilot investigation of oat beta-glucans and other fibers as mycotoxin alleviators for feed. Funded by Lantmännen, Sweden : Member of ResAzoleNet, a Network to increase awareness of Azole Resistance development in Aspergillus. Funded by the NRC : Leader of the Strategic Institute Program Fungi and Mycotoxins in a one health perspective (FUNtox-SIS), internal funding NVI : Project leader of the research project Mycotoxins in cereal based food products of wheat and oats - Effect of processing on free and masked mycotoxins and human risk assessment (MycoProcess) funded by the Norwegian Research Council and The Norwegian Agricultural Agency, FFL/ JA program (NFR #233770). 6 partners : Post doctor in the project Mycotoxin contamination in oats, - characterization of the infection process by the major T-2 and HT-2 toxin producer Fusarium langsethiae funded by the Norwegian Research Council and The Norwegian Agricultural Agency, FFL/ JA program : Research associate of the NFR funded project Functional studies of key regulatory genes involved in cell fate specification of aleurone cells with application to cereal breeding, UMB. 2005: Research associate of the NFR funded project Acaricide resistance in two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae), Bioforsk. 2004: Participant in EU Research Training Network, grant no. RTN : Project leader of personal FRIPRO stipend from the Norwegian Research Council during Ph.D.

2 TEACHING, SUPERVISION, LEADERSHIP : Main contact for Prof. Carlos Oliveira, visiting scientist in FUNtox 2017: Ass. supervisor for ERASMUS student Stephen Depoorter, Belgium 2016: Supervisor for exchange student Thais Sultani, Brazil : Supervisor for M.Sc. students Martha Tveit and Lise Bøe, Bioforsk 2007: Lecturer in Developmental Biology (BIO320), UMB : Ass. supervisor for Marten van den Linden, Master student, UMB 2003: Supervisor for Ofer Hochberg, summer-student, WIS 2002: Mentor for Taylan Ozdere, summer-student, WIS 1998: Assistant teacher in lab course, basic genetics, UMB EDUCATION, COURSES AND PREVIOUS WORK EXPERIENCE Transcriptomics data analysis course. NVI, Oslo, DNA methylation data analysis workshop. ECSEQ Bioinformatics, Berlin, Research leadership programme 2014, University of Oslo : Researcher/post doc, Norwegian Institute for Agricultural and Environmental Research, Bioforsk : Researcher, Norwegian University of Life Sciences, Department of Plant and Environmental Sciences : Temporary Post Doc, Norwegian Institute for Agricultural and Environmental Research, Bioforsk. Ph.D. in molecular biology, Weizmann Institute of Science, Plant Science Department, Israel July The Ph.D. study was funded by grants from the Norwegian Research Council and an RTN EU research program. M.Sc. in bioteknology, Norwegian Agricultural University, Norway, August PUBLICATIONS Hannah Reynolds, Jason C. Slot, Hege H. Divon, Erik Lysøe, Robert H. Proctor, and Daren W. Brown Differential retention of gene functions in a secondary metabolite cluster. Molecular Biology and Evolution; doi: /molbev/msx145. L. Ivanova, S. Sahlstrøm, I. Rud, S. Uhlig, C. K. Fæste, G. S. Eriksen, and H. H. Divon Effect of primary processing on the distribution of free and modified Fusarium mycotoxins in naturally contaminated oats. World Mycotoxin Journal 10 (1) - Pages: 73 88; doi.org/ /wmj Erik Lysøe, Rasmus J.N. Frandsen, Hege H. Divon, Valeria Terzi, Luigi Orrù, Antonella Lamontanara, Anna-Karin Kolseth, Kristian F. Nielsen, Ulf Thrane Draft genome sequence and chemical profiling of Fusarium langsethiae, an emerging producer of type A trichothecenes. International Journal of Food Microbiology 221: E. Lysøe, L.J. Harris, S. Walkowiak, R. Subramaniam, H. H. Divon, E.S. Riiser, C.Llorens, T. Gabaldon, H. C. Kistler, W. Jonkers, A-K. Kolseth, K. F. Nielsen, U. Thrane, R. J.N. Frandsen (2014) The genome of the generalist plant pathogen Fusarium avenaceum is

3 enriched with genes involved in redox, signaling and secondary metabolism. PLOS ONE 9: e Hege H. Divon, Jafar Razzaghian, Heidi Udnes-Aamot, and Sonja S. Klemsdal (2012) Fusarium langsethiae (Torp and Nirenberg), investigation of alternative infection routes in oats. European Journal of Plant Pathology, 132: Lene T. Olsen, Hege H. Divon, Ronald Al, Kjetil Fosnes, Stein Erik Lid, Hilde-Gunn Opsahl- Sorteberg (2008) The defective seed 5 (des5) mutant - effects on barley seed development and HvDek1, HvCr4 and HvSal1 gene regulation. Journal of Experimental Botany. 59: Hege H. Divon and Robert Fluhr (2007) Nutrition acquisition strategies during fungal infection of plants. (MiniReview) FEMS Microbiology Letters 266: Hege H. Divon, Carmit Ziv, Olga Davydov, Oded Yarden, Robert Fluhr (2006) The global nitrogen regulator, FNR1, regulates fungal nutrition-genes and fitness during Fusarium pathogenesis. Molecular Plant Pathology 7: Hege H. Divon (2005) Nutritional adaptation of Fusarium oxysporum during plant invasion. Ph.D. thesis. Weizmann Institute of Science, Israel. Hege H. Divon, Beatrice Rothan-Denoyes, Olga Davydov, Antonio Di Pietro, Robert Fluhr (2005) Nitrogen responsive genes are differentially regulated in planta during Fusarium oxysporum f. sp. lycopersici infection. Molecular Plant Pathology 6: Opsahl-Sorteberg HG, Hege H. Divon, Peter Stein Nielsen, Roger Kalla, Michael Hammond-Kosack, Ko Shimamoto and Ajay Kohli (2004) Identification of a 49 bp fragment of the HvLTP2 promoter directing aleurone cell specific expression. Gene 341: Hege H. Divon og Sonja Klemsdal (2012) Løser mykotoksingåten HT-2 og T-2 (2012). Norsk Landbruk Nr. 5: 93. Hege H. Divon (2013) Sopp spiser seg sterk på havrens hannorgan. Norsk Landbruk. Aksel Bernhoft, Ellen Christensen, Hege Divon, Thor A. Waaler, Trude Vrålstad, Gunnar S. Eriksen (2015) The surveillance programme for mould and mycotoxins in feed materials and complete feed in Norway 2014.Surveillance program for terrestrial and aquatic animals in Norway. Annual report Oslo: Norwegian Veterinary Institute. PRESENTATIONS AT CONFERENCES AND MEETINGS Nutrient preferences in F. langsethiae revealing competitive skills. H.H. Divon, I. Lojack and S.S. Klemsdal. Poster. European Fusarium Seminar 14, Tulln, Austria Mykotoksiner i grensesnittet mellom mattrygghet og matsikkerhet. H.H. Divon. Presentation. NIBIO-conference The depudecin cluster a genetic curiosity in Fusarium langsethiae. H.H. Divon, E. Lysøe, T. Sultani, L. Ivanova, R.H. Proctor, D.W. Brown. Poster. Nordic-Baltic Fusarium Smeinar, Riga, Lithuania, 2017.

4 Soppgift i fôret kan påvirke forløpet av PRV-infeksjon hos laks. Moldal, Torfinn; Alarcon, Marta; Hauge, Helena; Divon, Hege; Thoen, Even; Wiik-Nielsen, Jannicke; Ivanova, Lada; Gjevre, Anne Gerd; Dahle, Maria Krudtaa; Grove, Søren. Presentation. FRISK FISK A platform for integrated studies of fungi and mycotoxins in a One Health perspective. Hege H. Divon, S. Uhlig, C.K. Fæste, H. Wisløff. Poster, International Mycology Conference, Bangkok August Synopsis of microscopic and molecular studies in F. langsethiae pathogenicity. Hege H. Divon, Erik Lysøe and Sonja S. Klemsdal. Abstract and Presentation, EFS12th Bordeaux May Retention of genes in a secondary metabolite gene cluster that has degenerated in multiple lineages of the Ascomycota. Daren W. Brown1, Hege H. Divon2, Erik Lysøe3 and Robert H. Proctor. Poster. Asilomar conference Bioaktive naturstoffer i korn, mer enn bare kjente mykotoksiner? Erik Lysøe, Hege Divon, Sonja Klemsdal. Abstract, Bioforsk conference, February Histological studies of Fusarium langsethiae on oats.hege H. Divon, Lise Bøe, Martha Tveit and Sonja S. Klemsdal. Accepted seminar at the NBFS 2012, Uppsala, Sweden, October Fusarium langsethiae parasite or endophyte? Investigation of alternative routes for plant colonization. (Seminar) Hege H. Divon. 11th European Fusarium Seminar, Warsaw, Poland. September Fusarium langsethiae in oats investigation of alternative infection routes. (Seminar) Hege H. Divon. Nordforsk Fusarium Workshop, Uppsala, Sweden. April Nutritional adaptation of Fusarium oxysporum during plant invasion. (Seminar) Hege H. Divon. Dept. of Plant Science, Weizmann Institute of Science, Rehovot, Israel. July Nutritional adaptation of Fusarium oxysporum during plant invasion. (Seminar) Hege H. Divon. Israeli Molecular Mycology Meeting, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel. June Gene expression during stress and in planta conditions in Fusarium oxysporum f.sp. lycopersici. (Seminar) Hege H. Divon. Norwegian Institute for Agricultural and Environmental Research, Bioforsk, Ås, Norway. Dec Stress and innate immune responses in plants. (Poster) Cher Ashtamker, Olga Davydov, Ofra Hadrian, Hege H. Divon, Hadas Ner-Gaon and Yehudit Zohar. Open Day, Weizmann Institute of Science, Rehovot, Israel. May Gene expression during stress and in planta conditions in Fusarium oxysporum f.sp. lycopersici. (Seminar) Hege H. Divon. RTN EU research grant (No. RTN ) meeting, Wageningen, Holland. Oct

5 Nutrient stress and expression of fungal genes in relation to pathogenesis. (Seminar) Hege H. Divon. Israeli Molecular Mycology Meeting, Tel Aviv University, Tel-Aviv, Israel. June Comparison of transcriptomes of Fusarium oxysporum f.sp. lycopersici, race 2, during stress and infection. (Poster) Beatrice Rothan, Hege H. Lund, Olga Davydov. Open Day, Weizmann Institute of Science, Rehovot, Israel. January Innate Immunity Pathogen Recognition in Plants. (Abstract) Robert Fluhr, Ofra Budai- Hadrian, Olga Davydov, Hege Lund, Qilin Pan, Odelia Pisanty, Moshe Sagi, Sigal Savaldi- Goldstein, Marianne B. Sela-Buurlage, Ada Viterbo-Fainzilber, Hongming Zhang and Ron Vunsh. Israel Society for Plant Sciences, Beit Dagan, Israel. February 2000.

Mycotoxin Prevention in Cereal Crops by Enhanced Host Plant Resistance an update October2008

Mycotoxin Prevention in Cereal Crops by Enhanced Host Plant Resistance an update October2008 UMB; Åsmund Bjørnstad, Helge Skinnes, et al BIOFORSK: Sonja Klemsdal, Erik Lysøe et al. UMN: Jim Anderson, Howard