Curriculum Vitae. Stages of University education From To Position Institution, city, country Degrees/Remarks

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1 Curriculum Vitae Personal Information Family name : Ibrahim First name : Sherif Date of Birth : Nationality : Egyptian Gender : Male Marital status : Married, one son Position Title : Dr.rer.nat Present address : Cancer Biology Laboratory, Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt, Phone: , Fax: sheriefabdelaziz@yahoo.com, sherif3eg@hotmail.com Language Proficiency Arabic Fluent spoken and written (Mother tongue) English Fluent spoken and written German Fair spoken and written Academic degrees Year Degree University Country Subject of examination Grade 2011 Ph.D Münster Germany Biology Magna cum laude 2006 M. Sc. Cairo Egypt Comparative Physiology NA 2001 B. Sc. Cairo Egypt Zoology, Chemistry Very good with honor Stages of University education From To Position Institution, city, country Degrees/Remarks DAAD promotion Scholarship Münster University Hospital, Dr.rer.nat Demonstrator Zoology Dep., Fac. of Science, Cairo Uni., Egypt M.Sc Student Zoology and Chemistry Dep., Fac. of Science, Cairo Uni., Egypt B.Sc Professional background From To Position Institution City, Country 11. Present Lecturer Zoology Dep., Fac. of Science Cairo Uni., Giza, Egypt Postdoc Münster University Hospital DAAD promotion Scholarship Münster University Hospital Assistant Lecturer Zoology Dep., Fac. of Science Cairo Uni., Giza, Egypt Demonstrator Zoology Dep., Fac. of Science, Cairo Uni., Giza, Egypt Visitor researcher Egyptian Reference Diagnostic Center (ERDC) Egyptian Organization for Biological Products and Vaccines (VACSERA). Worked in Hepatitis C Project funded by Welcome Trust, UK Giza, Egypt - 1 -

2 Periods in Germany From To Position Financed by Scientific mentor German course visitor DAAD Goethe Institute, Göttingen PhD student DAAD Postdoc Münster University Hospital Priv.Doz.Dr. Martin Götte, Münster University Hospital, Priv.Doz.Dr. Martin Götte, Münster University Hospital, Periods abroad From To Position Financed by Scientific mentor Visitor Trainee (2 weeks) DFG, CNPq Dr. Mauro Pavao, PhD, Glycobiology program coordinator Laboratory of Connective Tissue, Institute of Medical Biochemistry, Caixa Postal 68041, Rio de Janeiro, Brazil Thesis Titles M.Sc Thesis: Ibrahim SA ( ): Role of p53 protein in apoptosis of hepatic cell carcinoma. Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt. Ph.D Thesis: Ibrahim SA ( ): Functional analysis of Syndecan-1, a novel target of mir-10b, in breast cancer progression. Department of Gynecology and Obstetrics, Münster University Hospital, Westfälische-Wihelms-Münster Uni.,

3 Training/Workshops Year Institution, City, Country 2013 People of the EU 7th R&D Framework Programme Information Day, 3 June, Cairo Uni., Giza, Egypt 2013 Developing a personality of leadership module, on 30 May DAAD Cairo, Egypt 2013 Biostatics course, May, Faculty of Science, Cairo Uni, Egypt E-learning course, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt Conference organization course, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt Competing for research funds, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt Research ethics course, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt University code of ethics, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt Use of technology in teaching course, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt The credit hour systems course, Nov Faculty and Leadership Development Center, Cairo Uni., Giza, Egypt International publishing of scientific research course, Nov Faculty and Leadership Development Center, Cairo Uni, Giza, Egypt rd NRW Stem Cell School Dec Muenster, NRW, Germany 2011 ZEISS on your Campus, July 26-27, Muenster Uni., Muenster, Germany 2011 Project management for young scientists on 28 June, Graduate School Life Science, Muenster Uni., Muenster, Germany 2011 Academic presentation skills course, June 15-16, Graduate School Life Science, Muenster Uni., Muenster, Germany 2010 Laboratory of Connective Tissue, Institute of Medical Biochemistry, Caixa Postal 68041, Rio de Janeiro, Brasil for 2 weeks 2010 Quantitative real time PCR seminar, 18 May Bio-Rad, Muenster, Germany 2008 Living Cells workshop by Zeiss, April Physiological chemistry dep., Muenster Uni., Muenster, Germany 2006 Molecular Immunology Workshop, Theory, Practice and Applications, July Medical Technology Center, Medical Research Institute, Alexandria University, Egypt 2004 Grant writing workshop, Jan National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt 2004 Atomic absorption, Chromatographic separation, water and biological analysis workshop, April Micro- Analytical center, Faculty of Science, Cairo University, Egypt Molecular Biology Department, National Research Center, Dokki, Giza, Egypt for 6 months Conferences Participation in 17 international conferences (list is available upon request). Teaching Service at Cairo University From 2001 Weekly teaching sessions: - Practical systematic Zoology courses for predental, prepharmacy, preveterinary and first year science students. - Practical Biochemistry courses for 3 rd year and B.Sc. Zoology students (course # Zo351). - Practical Hematology courses for 3 rd year and B.Sc. Zoology students (course # Zo352). - Practical Muscle Physiology courses for B.Sc. Zoology students (course # Zo451). - Practical Immunology courses for 2 nd year biology/chemistry students (course # Zo212)

4 Recognition and awards 2013 Cairo University International Publication Award Cairo University International Publication Award promotion scholarship from DAAD, Germany 2006 Honored by social club of Cairo University 2001 Honored by Cairo University as the top graduated students Conference Organization and Attendance 2004 University of Maryland Baltimore, Health Research Projects, Cairo, Egypt. Professional membership A member of the German Society for Cell Biology (DGZ). Publications 1. Ibrahim SA, Hassan H, Schneider C, Kelsch R, Reinbold R, Kiesel L, Greve B, Götte M. Syndecan-1 (CD138) modulates breast cancer stem cell properties via regulation of IL-6- mediated STAT3 signaling. Plos, under revision 2. Hassan H, Greve B, Pavao MS, Kiesel L, Ibrahim SA, Götte M. Syndecan-1 modulates beta-integrin- and IL-6-dependent functions in breast cancer cell adhesion, migration and resistance to irradiation. FEBS J May;280(10): Ibrahim SA, Yip GW, Stock C, Pan JW, Neubauer C, Poeter M, Pupjalis D, Koo CY, Kelsch R, Schüle R, Rescher U, Kiesel L, Götte M. Targeting of syndecan-1 by microrna mir-10b promotes breast cancer cell motility and invasiveness via a Rho- GTPase- and E-cadherin-dependent mechanism. Int J Cancer. Sep 15; 131(6):E Ezeddin Salem Gassar, Sherif A. Ibrahim, Götte Martin. Heparan sulfate proteoglycans in cancer progression and therapy. in " Glycans in Diseases and Therapeutics". Series, Biology of Extracellular Matrix, Editor: Pavão M. Springer Berlin Heidelberg publisher, 2011, pp Götte M, Mohr C, Koo CY, Stock C, Vaske AK, Viola M, Ibrahim SA, Peddibhotla S, Teng YH, Low JY, Ebnet K, Kiesel L, Yip GW. mir-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness. Oncogene Dec 16;29(50): Nikolova V, Koo CY, Ibrahim SA, Wang Z, Spillmann D, Dreier R, Kelsch R, Fischgräbe J, Smollich M, Rossi LH, Sibrowski W, Wülfing P, Kiesel L, Yip GW, Götte M. Differential roles for membrane-bound and soluble syndecan-1 (CD138) in breast cancer progression. Carcinogenesis Mar;30(3): Ibrahim SA, Abdelwahab SF, Mohamed MM, Osman AM, Fathy E, Al-Badry KS, Al-Kady N, Esmat GE, Al-Sherbiny MM. T cells are depleted in HCV-Induced hepatocellular carcinoma patients: possible role of apoptosis and p53. Egypt J Immunol. 2006;13(2): References/Referees 1. Priv.-Doz. Dr. Martin Götte, PhD, Department of Gynecology and Obstetrics, Münster University Hospital, Albert- Schweitzer Campus 1, D11, 48149, Phone: , goettema@ukmuenster.de. 2. Priv.-Doz. Dr. Burkhard Greve, PhD, Department of Radiotherapy Radiooncology, Münster University Hospital, Albert- Schweitzer, Campus 1, 48149, Phone: , greveb@uni-muenster.de. 3. Associate Prof. Dr. Mauro Pavao, PhD, Glycobiology program co-odrinator, Laboratory of Connective Tissue, Institute of Medical Biochemistry, Caixa Postal Rio de Janeiro, Brazil, Phone: , pmourao@hucff.ufrj.br

5 4. Associate Prof. Dr. Manula Viola, PhD, Department of Experimental and clinical Biomedical Sciences, Insubria University, Varese, Italy, Phone: , Prof. Dr. Maged M. Al-sherbiny, Department of Zoology, Faculty of science, Cairo University, Giza, Egypt, Phone: , 6. Prof. Dr. Mona Mostafa Mohamed, Breast Cancer Biology Laboratory, Zoology Department, Faculty of Science, Cairo University, Giza, Egypt, Phone; , 7. Associate Prof. Dr. Sayed F. Abdelwahab, Department of Microbiology and Immunology, Faculty of Medicine, El-Minia University, El-Minia, Egypt. Phone: ,