Small Intestine, Large Intestine and anal cannel
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1 Small Intestine, Large Intestine and anal cannel Small intestine Large intestine Small intestine
2 General Structure of the Digestive Tract rat Epithelium with goblet cells and absorptive cells Lamina propria central lacteal Muscularis mucosa Submucosa Muscularis externa (tunica muscularis) Serosa
3 Slide #37 (Ed b). Small intestine, donkey. Mesothelium of serosa tunica muscularis neuronal cell bodies of the submucosal ( Meissner s) plexus the myenteric ( Auerbach s) plexus located between the inner circular and outer longitudinal smooth muscle layers of the tunica muscularis submucosal (Brunner s) glands intestinal crypts (glands of Lieberkuhn) muscularis mucosa lamina propria central lacteal muscularis mucosa
4 Slide #37 (Ed b). Small intestine, donkey. Intestinal absorptive cells Simple columnar epithelium Paneth cells Goblet cell Paneth cell brush or striated border = High density of non-branching microvilli of uniform length. Microfilaments are the cytoskeleton component in microvilli
5 Paneth cells Slide #37 (Ed b). Small intestine, donkey Absorptive cells Enteroendocrine Cells (EC cells) Mitotic figures
6 Enteroendocrine cells in fundic stomach, rabbit (toluidine blue) To see the distribution of EC cells among glands 244 Chief cells Enteroendocrine cells Parietal cell
7 146 Duodenum, monkey Crypts of Lieberkühn Enteroendocrine cell Goblet and absorptive cells, Muscularis mucosa Lamina propria. Submucosa Submucosal Brunner's glands.
8 152 Duodenum Brunner s glands Absorptive cells Goblet cells Paneth cell Intestinal villus Enteroendocrine cell
9 Slide #37 (Ed b). Small intestine, donkey. Enteroendocrine cells
10 DEMO SLIDE BOX 57 - Small intestine (ileum), dog. oblet cell Intestinal crypts (glands Or Crypts of Lieberkuhn Peyer s patches lamina propria of the villi central lacteals Smooth Muscle in Intestinal villus
11 DEMO SLIDE BOX 57 - Small intestine (ileum), dog. Enteroendocrine cell Intestinal crypts (glands Or Crypts of Lieberkuhn
12 DEMO SLIDE BOX 225 (C- H- 73). Small intestine (jejunum), dog. Absorptive cells epithelial Modifications = Brush border and goblet cells central lacteal Strips of Muscularis mucosa lamina subglandularis muscularis mucosa submucosa
13 DEMOSLIDE BOX 225 (C- H- 73). Small intestine (jejunum), dog. lamina subglandularis stratum compactum stratum granulosum muscularis mucosa submucosa lamina subglandularis Enteroendocrine cells Paneth cells Absorptive cells
14 Mesothelium of serosa DEMOSLIDE BOX 225 (C- H- 73). Small intestine (jejunum), dog. Crypts of Lieberkuhn lamina subglandularis muscularis mucosa Submucosal ( Meissner s ) submucosa tunica muscularis Smooth muscle cells serosa. myenteric ( Auerbach s ) plexuses
15 Slide #192 (Pf 5-84d). Small intestine (jejunum), pig.. submucosa Absorptive cells lamina propria tunica muscularis muscularis mucosa
16 Slide #192 (Pf 5-84d). Small intestine (jejunum), pig. Intestinal absorptive cells Simple columnar epithelium central lacteal Brush border of absorptive cells Smooth muscle cells of the muscularis mucosa lamina propria Goblet cell Paneth cells Enteroendocrine cells
17 Slide #89 (83 DF1) Small intestine, puppy (dog). Epithelium Lamina propria Muscularis mucosa Submucosa tunica muscularis Serosa
18 Slide #89 (83 DF1) Small intestine, puppy (dog). Lymph nodules Intestinal crypts (glands Or Crypts of Lieberkuhn Small intestinal villi central lacteal
19 Slide #89 (83 DF1) Small intestine, puppy (dog). Dividing cells Epithelium Lamina propria myenteric ( Auerbach s ) plexuses Muscularis mucosa (developing) Submucosa with lymphoid cell infiltration tunica muscularis Serosa Serosa mesothelium
20 Compare luminal surfaces of the small and large intestines small intestines Villi large intestines NO Villi
21 DEMO SLIDE BOX 167 (C003- H- 29) - Large intestine (cecum), dog. villi are absent Epithelium Lamina propria Smooth muscle Muscularis mucosa Submucosa tunica muscularis Serosa Lymph nodules Peyer s patches Intestinal crypts (glands Or Crypts of Lieberkuhn
22 DEMO SLIDE BOX 167 (C003- H- 29) - Large intestine (cecum), dog. Epithelium Lamina propria villi are absent Intestinal crypts (glands Or Crypts of Lieberkuhn Muscularis mucosa absorptive cells and goblet cells Enteroendocrine cells
23 DEMO SLIDE BOX 61. Large intestine (colon), cat. Epithelium Lamina propria Muscularis mucosa (developing) Submucosa with lymphoid cell infiltration tunica muscularis Serosa
24 DEMO SLIDE BOX 61. Large intestine (colon), cat. Intestinal crypts (glands Or Crypts of Lieberkuhn Epithelium Lamina propria absorptive cells goblet cells Muscularis mucosa Submucosa
25 DEMO SLIDE BOX 171 (E3- H- 38). Large intestine (colon), horse. the taenia coli; a gross thickening of the longitudinal layer of tunica muscularis in the horse. taenia coli Lymph nodules Intestinal crypts (glands Or Crypts of Lieberkuhn
26
27 DEMO SLIDE BOX 168 (C003- H- 38) - Large intestine (colon), dog. Intestinal crypts (glands Or Crypts of Lieberkuhn Epithelium with goblet cells and absorptive cells Lamina propria Muscularis mucosa Submucosa Muscularis externa (tunica muscularis) Serosa
28 DEMO SLIDE BOX 168 (C003- H- 38) - Large intestine (colon), dog. Enteroendocrine cells Intestinal crypts (glands Or Crypts of Lieberkuhn
29 Slide #43 (K9-1). Anal region, dog. the recto- anal junction and regional skin. rectum skin goblet cells located in the crypts rectum regional skin nonkeratinized stratified squamous epithelium circumanal glands (perianal glands) which can become neoplastic
30 Slide #43 (K9-1). Anal region, dog. keratinized stratified squamous epithelium
31 Slide #43 (K9-1). Anal region, dog the circumanal glands (perianal glands) in this region CCT Walled off with CCT parasite external anal sphincter = bundles of skeletal muscle
32 DEMO SLIDE BOX 62- Rectum and anal canal, dog. simple columnar epithelium the circumanal (perianal) glands skin large invagination of the anal sac. rectum
33 Again the simple columnar epithelium is missing. Note the approximate recto- anal junction. At this junction, there is an abrupt change to nonkeratinized stratified squamous epithelium. Near the junction of nonkeratinized and keratinized stratified squamous epithelium, observe the large invagination of the anal sac. The inner circular layer of the tunica muscularis is somewhat thickened to form the internal anal sphincter. The skeletal muscle fibers are part of the external anal sphincter. The anal canal is continuous with the skin of the perineal region (note the change in epithelium to keratinized stratified squamous); see the circumanal (perianal) glands
34 DEMO SLIDE BOX 62- Rectum and anal canal, dog. the circumanal (perianal) glands keratinized stratified squamous skeletal muscle fibers are part of the external anal sphincter skin skin nonkeratinized stratified squamous epithelium rectum tunica muscularis (smooth muscle) is somewhat thickened to form the internal anal sphincter. large invagination of the anal sac. rectum
35 Large intestine or Colon, monkey
36 MUCOCUTANEOUS JUNCTIONS
37 Slide 66: Recto-anal junction External anal sphincter Internal anal sphincter Anus Rectum
38 Slide 66 : Recto-anal junction Keratinized stratified squamous epithelium Hair follicles Sebaceous glands Gland ducts Apocrine glands Anus
39 Digestive tract distinguishing features human summary Mucosa (epithelium, lamina propria, muscularis mucosa) Submucosa (with submucosal plexuses) Muscularis (Inner circular and outer longitudinal layers, with myenteric plexuses between them) Adventitia/ Serosa Esophagus (upper, middle, lower) Nonkeratinized stratified squamous epithelium; cardiac glands at lower end Small esophageal glands (mainly mucous) Both layers striated muscle in upper region; both layers smooth muscle in lower region; smooth and striated muscle fascicles mingled in middle region Adventitia, except at lower end with serosa Stomach (cardia, fundus, body, pylorus) Surface mucous cells, and gastric pits leading to gastric glands with parietal and chief cells, (in the fundus and body) or to mucous cardiac glands and pyloric glands No distinguishing features Three indistinct layers of smooth muscle (inner oblique, middle circular, and outer longitudinal) Serosa Small intestine (duodenum, jejunum, ileum) Plicae circulares; villi, with enterocytes and goblet cells, and crypts/glands with Paneth cells and stem cells; Peyer patches in ileum Duodenal (Brunner) glands (entirely mucous); possible extensions of Peyer patches in ileum No distinguishing features Mainly serosa Large intestine (cecum, colon, rectum) Intestinal glands with goblet cells and absorptive cells No distinguishing features Outer longitudinal layer separated into three bands, the teniae colo Mainly serosa, with adventitia at rectum Anal canal Stratified squamous epithelium; longitudinal anal columns Venous sinuses Inner circular layer thickened as internal sphincter Adventitia
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