11: Pathways. Reminders:

Transcription

1 11: Pathways Reminders: 1. Due in lab NEXT week: a. Pre- Lab 05 b. Amylase lab report 2. Exam 4 Monday (see SPOC for details) Last names A F Ryan Lounge M Last names G - Z here (1 pt for right room)

2 iclicker Question 1: Consider the following reaction: A Xase B What are A and B? C A. Small molecules. B. ATP and ADP + Pi, respectively. C. Enzymes D. Substrates for Xase. E. Products of Xase. D

3 iclicker Question 2: Consider the following reaction: A Xase B What are C and D? C A. Small molecules. B. ATP and ADP + Pi, respectively. C. Enzymes D. Substrates for Xase. E. Products of Xase. D

4 iclicker Question 3: Consider the following reaction: A Xase B What is Xase? A. A small molecule. C D B. The enzyme that catalyzes the reaction A+Bè C+D. C. An enzyme D. The name of the reaction. E. None of the above.

5 iclicker Question 4: If a typical substrate molecule were the size of a person, how big would a typical enzyme molecule be? A. The size of a soccer ball. B. The size of a person. C. The size of a car. D. The size of a house. E. The size of the state of Massachusetts.

6 iclicker Question 5: Why is vitamin C a vitamin? A. It is necessary for healthy life. B. It is necessary for life and humans can t make it ourselves. C. It is necessary for all living things. D. It is necessary for all animals. E. None of the above.

7 iclicker Question 6: Consider the pathway for the synthesis of vitamin C. Which of these is true? A. The activation energy of the last step is lower than that of the second- to- last step. B. The activation energy of the last step is higher than that of the second- to- last step. C. The ΔG of the last step is lower than that of the second- to- last step. D. The ΔG of the last step is higher than that of the second- to- last step. E. You cannot tell from the information given.

8 iclicker Question 7: Consider the pathway for the synthesis of vitamin C. Which of these is likely to be true? A. Humans have all 4 enzymes in the pathway. B. No organism has all 4 enzymes in the pathway. C. Citrus fruits have all 4 enzymes in the pathway; humans lack one or more. D. All organisms have all 4 enzymes in the pathway. E. No organisms have any of the enzymes in the pathway.

9 iclicker Question 8: Which of the following molecules could substitute for vitamin C in humans? A. Glucose. B. Glucuronic acid. C. Gulonic acid D. Gulono lactone. E. None of the above.

10 iclicker Question 9: Consider the pathway of breakdown of phenylanine (phe). Some humans are unable to make the enzyme PAH; this results in a disease called phenylketonuria (PKU). Which molecule would accumulate people with PKU? A. All 20 amino acids. B. Phenylalanine. C. Tyrosine. D. Homogentisate. E. None of the above.

11 iclicker Question 10: Eating which of the following could reduce the symptoms of PKU in a PKU patient eating a normal diet? A. Phenylalanine. B. Tyrosine. C. 4- hydroxy- phenylpyruvate D. Homogentisate. E. None of the above.

12 iclicker Question 11: How much phe can a person with PKU eat each day and not get brain damage? A. 0 g because any amount of phe is too much. B. 0.1 g C. 0.5 g D. 1.5 g E. 2.0 g

13 iclicker Question 12: How much phe can a normal person (makes plenty of PAH) eat each day and not get brain damage? A. 0 g because any amount of phe is too much. B. 0.1 g C. 0.5 g D. 1.5 g E. Can t tell from the information given.