Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

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1 Laboratory locations: 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Biochemistry Pathology First Hub Laboratory, Bentalls, Basildon. Essex SS14 3BY Contact: Kim Aston Tel: +44 (0) kim.aston@ipp-uk.com below s covered by the organisation and their relevant activities details Activity code Pathology First Hub Laboratory, Bentalls, Basildon. Essex SS14 3BY Local Contact: Simon Chapman Clinical Biochemistry and Immunology Pathology Department Basildon Hospital Level C, Basildon University Hospital Nethermayne Basildon SS16 5NL Local contact: Paul Mackenzie Clinical Biochemistry and Immunology Pathology Department Southend Hospital 2 nd Floor Prittlewell Wing. Southend University Hospital Prittlewell Chase Westcliff on sea SS0 0RY Local contact: Paul MacKenzie Clincial Biochemistry and Immunology Assessment Manager: EB 1 of 18

2 DETAIL OF ACCREDITATION clinical diagnosis Beckman Coulter AU5800 or AU680 analysers with random access colorimetry or turbidimetry Therapeutic drug monitoring and drugs of abuse screening PF-BIO-LP-6 PF-BIO-LP-3 Serum/Plasma Amikacin Carbamazepine Gentamicin Paracetamol Salicylate Theophylline Vancomycin Digoxin Phenytoin Lithium Assessment Manager: EB Page 2 of 18

3 Beckman Coulter AU5800 analysers with random access colorimetry or turbidimetry Whole blood Cyclosporin PF-BIO-LP-6 PF-BIO-LP-3 Beckman Coulter AU5800 or AU680 analysers with random access colorimetry or turbidimetry Biochemical marker analysis: Alpha 1 Anti-trypsin Haptoglobin Transferrin PF-BIO-LP-6 Beckman Coulter AU5800 or AU680 analysers with random access colorimetry or turbidimetry Biochemical marker analysis: Bicarbonate PF-BIO-LP-3 PF-BIO-LP-6 Iron Assessment Manager: EB Page 3 of 18

4 Beckman Coulter AU5800 or AU680 analysers with random access colorimetry or turbidimetry Biochemical marker analysis: Conjugated Bilirubin Ammonia Bile Acids Ethanol PF-BIO-LP-3 Beckman Coulter AU5800 or AU680 analysers with ion selective electrode Electrolyte analysis: Serum/Plasma/Urine Sodium Potassium Chloride PF-BIO-LP-3 PF-BIO-LP-6 Assessment Manager: EB Page 4 of 18

5 Beckman Coulter AU5800 analysers with random access colorimetry or turbidimetry Routine biochemistry tests Serum/Plasma Albumin ALP ALT Amylase AST Total Bilirubin Calcium Cholesterol CK Creatinine(Enzymatic) GGT Glucose HDL cholesterol LDH Magnesium Phosphate Total Protein Triglycerides Urate Urea PF-BIO-LP-3 PF-BIO-LP-6 Beckman Coulter DxI 800 routine biochemistry testing: Serum/Plasma Vitamin D PF-BIO-LP-2 Assessment Manager: EB Page 5 of 18

6 Beckman AU5800 or AU680 analysers with random access colorimetry, turbidimetry Routine Biochemistry Testing: Urine Creatinine Potassium Total protein Sodium Urate Urea Phosphate Albumin Calcium Chloride PF-BIO-LP-3 PF-BIO-LP-6 Beckman AU5800 or AU680 analysers with random access colorimetry, turbidimetry Routine Biochemistry Testing: Urine Catecholamines PF BIO LP 49 Assessment Manager: EB Page 6 of 18

7 Beckman AU5800 or AU680 analysers with random access colorimetry, turbidimetry Routine Biochemistry Testing: Cerebral Spinal Fluid Glucose Total Protein Lactate PF-BIO-LP-3 Beckman AU5800 or AU680 analysers with random access colorimetry, turbidimetry Biochemistry Immunological testing: PF-BIO-LP-3 PF-BIO-LP-6 CRP Assessment Manager: EB Page 7 of 18

8 Beckman AU5800 or AU680 analysers with random access colorimetry, turbidimetry Biochemistry Immunological testing: C3 C4 IgA IgG IgM Rheumatoid factor II Immunoglobulin E PF-BIO-LP-6 Beckman Coulter DxI 800/Access 2 for Electrochemiluminescence immunoassay: B12 Cortisol Ferritin Folate FSH FT3 LH Oestradiol Prolactin Macroprolactin PSA PTH SHGB Testosterone Thyroid peroxidase antibodies (TPO) PF-BIO-LP-2 Assessment Manager: EB Page 8 of 18

9 Beckman Coulter DxI 800/Access 2 for Electrochemiluminescence immunoassay: Cortisol FT4 bhcg Progesterone TSH PF-BIO-LP-1 Roche Cobas E411 random access colorimetry or turbidimetry or chemiluminescence technology for tumour markers: AFP Ca-125 Ca-199 Ca-153 CEA PF-BIO-LF-9 Roche Cobas E411 random access colorimetry or turbidimetry or chemiluminescence technology for cardiac markers: NT-Pro-BNP PF-BIO-LF-9 Roche Cobas E411 random access colorimetry or turbidimetry or chemiluminescence technology for cardiac markers: Troponin T PF-BIO-LF-9 Assessment Manager: EB Page 9 of 18

10 Sebia Capillarys 2 Flex Capillary electrophoresis BJP screen Serum Detection of serum proteins: Bence Jones Protein PF-BIO-LP-27 PF-BIO-LP-28 PF-BIO-LP-47 Sebia Hydrasys 2 Scan using serum and urine immunofixation electrophoresis. / Urine Paraprotein band(s) PF-BIO-LP-30 PF-BIO-LP-50 PF-BIO-LP-33 Sebia Hydrasys 2 Scan using serum and urine immunofixation electrophoresis. / Urine Identification of Bence Jones Proteins PF-BIO-LP-30 PF-BIO-LP-50 PF-BIO-LP-33 Assessment Manager: EB Page 10 of 18

11 Advanced Micro-Osmometer Model 3320 Measurement of depression of freezing point. Serum/Plasma/Urine Osmolality PF-BIO-LP-12 Quadratech4 FOB kits (faecal immunochemical test) Faeces Occult Blood CLINB-LP-70 Dynex DS2 for selective of calprotectin antigen by sandwich ELISA Faeces Calprotectin CLINB-LP-83 Spectrophotometric method using UVIKON xsr Spectrophotometry with Bio-c program. PF-BIO-LP-26 Cerebral Spinal Fluid Xanthochromia Spectrophotometric method using UVIKON xsr Spectrophotometry: Nicolette evolution 100 Cerebral Spinal Fluid Xanthochromia PF-BIO-LP-26 Assessment Manager: EB Page 11 of 18

12 SPA-Plus analyser using immunoturbidimetric Kappa and /or Lambda Free Light Chains PF-BIO-LF-179 CLINB-LP 107 Immunology examination clinical diagnosis Immulite 2000 :Electro chemiluminescence immunoassay PF-BSM-LP-8 Growth Hormone Sandwich immunoassay DHAS Competitive immunoassay Androstenedione Competitive immunoassay Erythropoetin Enhanced Sandwich immunoassay B2 Microglobulin Sandwich immunoassay Phadia 250 analysers with fluorescence enzyme immunoassay technology Almond Alternaria Apple Apricot Ara h2 peanut ARA H8 Specific IgE Aspergillus fumigatus Aspergillus fumigatus specific IgG Aspergillus niger PF-IMM-LP-7 I-LP-27 Assessment Manager: EB Page 12 of 18

13 Immunology examination Phadia 250 analysers with fluorescence enzyme immunoassay technology Avocado Banana Barley Basil Beef Black pepper Blackberry Blue Mussel Blueberry Brazil nut Broccoli Barley Basil Beef Black pepper Blackberry Blue Mussel Blueberry Brazil nut Broccoli Buckwheat Budgerigar feathers Budgerigar specific IgG Cabbage Cacao Candida albicans Cardamon Carrot Casein Cashew Cat dander CCP (IgG) Celery Cheddar cheese Cherry PF-IMM-LP-7 I-LP-27 Assessment Manager: EB Page 13 of 18

14 Immunology examination Phadia 250 analysers with fluorescence enzyme immunoassay technology Serum/Plasma Chick pea Chicken Chilli pepper Cladosporium herbarum Clam Clove Coconut Coffee Common ragweed Common wasp COR A8 specific IgE Coriander Cotton, crude fibres Cows milk Crab Cranberry Crayfish CTD Screen (ANA) Cucumber Curry (Santa Maria) Date Dog dander Duck feathers Egg white Egg yolk ENA Screen Fish (cod) Fish mix Food mix Fruit mix specific IgE Garlic Ginger Gluten Goat milk Goat epithelium PF-IMM-LP-7 I-LP-27 Assessment Manager: EB Page 14 of 18

15 Immunology examination Phadia 250 analysers with fluorescence enzyme immunoassay technology Serum/Plasma Grain mix Grape Grapefruit Grass mix Green bean Green pepper Guinea pig Haddock Hamster Lemon Lentil Lettuce Lime Lobster Lupine seed M2 Antibodies Macadamia nut Mackerel Maize/corn Mango Melon Micropolyspora faeni specific Mint Mosquito Rat mix Red Kidney bean Rice Rye Sage Salmon Scallop Sesame seed Sheep epithelium Shrimp Silver Birch PF-IMM-LP-7 I-LP-27 Assessment Manager: EB Page 15 of 18

16 Immunology examination Phadia 250 analysers with fluorescence enzyme immunoassay technology Soybean Squid Strawberry Sunflower seed Sweet Potato Tea Timothy grass Tomato Tree pollen mix UK Tryptase Tuna Walnut Wheat White bean Yeast PF-IMM-LP-7 I-LP-27 Assessment Manager: EB Page 16 of 18

17 Immunology examination Phadia 250 analysers with fluorescence enzyme immunoassay Anti-MPO Anti-PR3 Anti-TTG IgA Anti-cardiolipins (IgG and IgM) ENA CTD antibodies Ds DNA (EIA) Anti-TTG IgG Anti-GBM I-LP-27 I-LP-28 I-LP-33 I-LP-34 I-LP-35 I-LP-36 I-LP-37 I-LP-38 I-LP-1 I-LP-39 I-LP-40 Detection of autoantibodies: NovaLite monkey oesophagus slides using Indirect Immunofluorescence method Serum EMA IgG EMA IgA I-LP-23 I-LP-24 NovaLite ANCA slides using Indirect Immunofluorescence method I-LP-2 Serum ANCA abs Assessment Manager: EB Page 17 of 18

18 Immunology examination NovaLite Crithidia luciliae slides for intrinsic factor antibodies using Indirect Immunofluorescence method Serum Anti-dsDNA (crithida) I-LP-41 Biosystems HEp-2 slides using Indirect Immunofluorescence method Serum Anti-nuclear antibodies I-LP-1 Detection of autoantibodies using ImmuGlo mouse liver/kidney/stomach slides using Indirect Immunofluorescence method I-LP-14 Liver and pernicious anaemia END Assessment Manager: EB Page 18 of 18

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