Category GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT GOTERM_BP_FAT

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32 Term GO: ~regulation of transcription, DNA-dependent GO: ~regulation of RNA metabolic process GO: ~regulation of cell proliferation GO: ~regulation of transcription from RNA polymerase II promoter GO: ~positive regulation of macromolecule metabolic process GO: ~positive regulation of biosynthetic process GO: ~positive regulation of cellular biosynthetic process GO: ~skeletal system development GO: ~positive regulation of transcription from RNA polymerase II promoter GO: ~positive regulation of macromolecule biosynthetic process GO: ~positive regulation of nitrogen compound metabolic process GO: ~positive regulation of transcription, DNA-dependent GO: ~positive regulation of RNA metabolic process GO: ~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid GO: ~positive regulation of gene expression GO: ~pattern specification process GO: ~regulation of transcription GO: ~positive regulation of transcription GO: ~regionalization GO: ~embryonic morphogenesis GO: ~chordate embryonic development GO: ~embryonic development ending in birth or egg hatching GO: ~anterior/posterior pattern formation GO: ~positive regulation of cell proliferation GO: ~positive regulation of developmental process GO: ~response to organic substance GO: ~neuron differentiation GO: ~positive regulation of cell differentiation GO: ~response to steroid hormone stimulus GO: ~tube development GO: ~gland development GO: ~skeletal system morphogenesis GO: ~cell fate commitment GO: ~response to endogenous stimulus GO: ~response to hormone stimulus GO: ~embryonic organ development GO: ~regulation of cell death GO: ~regulation of programmed cell death GO: ~regulation of apoptosis GO: ~regulation of cell development GO: ~regulation of nervous system development GO: ~negative regulation of cell proliferation GO: ~embryonic organ morphogenesis GO: ~negative regulation of cell differentiation GO: ~embryonic skeletal system development GO: ~cell motion GO: ~appendage development GO: ~limb development GO: ~regulation of neurogenesis

33 GO: ~cell migration GO: ~limb morphogenesis GO: ~appendage morphogenesis GO: ~negative regulation of programmed cell death GO: ~negative regulation of cell death GO: ~sensory organ development GO: ~negative regulation of apoptosis GO: ~response to estrogen stimulus GO: ~transcription GO: ~cell motility GO: ~localization of cell GO: ~regulation of gene-specific transcription GO: ~response to extracellular stimulus GO: ~hemopoietic or lymphoid organ development GO: ~vasculature development GO: ~embryonic skeletal system morphogenesis GO: ~neuron development GO: ~blood vessel development GO: ~embryonic appendage morphogenesis GO: ~embryonic limb morphogenesis GO: ~positive regulation of multicellular organismal process GO: ~immune system development GO: ~forebrain development GO: ~response to nutrient levels GO: ~negative regulation of macromolecule metabolic process GO: ~regulation of neuron differentiation GO: ~negative regulation of cellular biosynthetic process GO: ~cell fate specification GO: ~negative regulation of biosynthetic process GO: ~negative regulation of nitrogen compound metabolic process GO: ~negative regulation of transcription from RNA polymerase II promoter GO: ~response to wounding GO: ~negative regulation of gene expression GO: ~tissue morphogenesis GO: ~negative regulation of macromolecule biosynthetic process GO: ~regulation of growth GO: ~negative regulation of nucleobase, nucleoside, nucleotide and nucleic ac GO: ~negative regulation of transcription GO: ~cartilage development GO: ~endocrine system development GO: ~enzyme linked receptor protein signaling pathway GO: ~negative regulation of transcription, DNA-dependent GO: ~positive regulation of cell death GO: ~negative regulation of RNA metabolic process GO: ~hemopoiesis GO: ~response to nutrient GO: ~positive regulation of apoptosis GO: ~positive regulation of programmed cell death GO: ~regulation of system process GO: ~regulation of neuron apoptosis

34 GO: ~epithelium development GO: ~cell-cell signaling GO: ~neuron fate commitment GO: ~respiratory system development GO: ~muscle organ development GO: ~blood vessel morphogenesis GO: ~tube morphogenesis GO: ~homeostatic process GO: ~positive regulation of cell communication GO: ~bone development GO: ~lung development GO: ~regulation of epithelial cell proliferation GO: ~muscle tissue development GO: ~neuron projection development GO: ~regulation of locomotion GO: ~transmembrane receptor protein tyrosine kinase signaling pathway GO: ~urogenital system development GO: ~respiratory tube development GO: ~positive regulation of signal transduction GO: ~regulation of phosphorylation GO: ~reproductive developmental process GO: ~cell proliferation GO: ~regulation of cell motion GO: ~heart development GO: ~response to drug GO: ~behavior GO: ~regulation of phosphorus metabolic process GO: ~regulation of phosphate metabolic process GO: ~striated muscle tissue development GO: ~response to abiotic stimulus GO: ~regulation of cell migration GO: ~positive regulation of phosphorylation GO: ~positive regulation of locomotion GO: ~positive regulation of cell motion GO: ~anti-apoptosis GO: ~positive regulation of phosphorus metabolic process GO: ~positive regulation of phosphate metabolic process GO: ~cell projection organization GO: ~regulation of specific transcription from RNA polymerase II promoter GO: ~ear development GO: ~positive regulation of gene-specific transcription GO: ~regulation of response to external stimulus GO: ~wound healing GO: ~response to oxygen levels GO: ~response to vitamin GO: ~positive regulation of cell migration GO: ~positive regulation of protein amino acid phosphorylation GO: ~regulation of protein amino acid phosphorylation GO: ~ossification GO: ~proximal/distal pattern formation

35 GO: ~cell morphogenesis involved in differentiation GO: ~morphogenesis of an epithelium GO: ~response to corticosteroid stimulus GO: ~response to molecule of bacterial origin GO: ~growth GO: ~response to hypoxia GO: ~cellular component morphogenesis GO: ~regulation of cell cycle GO: ~regeneration GO: ~positive regulation of cellular component organization GO: ~response to lipopolysaccharide GO: ~response to glucocorticoid stimulus GO: ~positive regulation of protein metabolic process GO: ~positive regulation of cellular protein metabolic process GO: ~neuron projection morphogenesis GO: ~mesenchyme development GO: ~regulation of cell adhesion GO: ~morphogenesis of a branching structure GO: ~axonogenesis GO: ~aging GO: ~developmental maturation GO: ~positive regulation of molecular function GO: ~response to organic cyclic substance GO: ~odontogenesis GO: ~leukocyte differentiation GO: ~regulation of protein modification process GO: ~chemical homeostasis GO: ~cell morphogenesis involved in neuron differentiation GO: ~regulation of ossification GO: ~response to peptide hormone stimulus GO: ~mammary gland development GO: ~cell morphogenesis GO: ~positive regulation of catalytic activity GO: ~regulation of cellular protein metabolic process GO: ~reproductive structure development GO: ~branching morphogenesis of a tube GO: ~mesenchymal cell development GO: ~negative regulation of neuron apoptosis GO: ~mesenchymal cell differentiation GO: ~regulation of cell growth GO: ~muscle cell differentiation GO: ~dorsal/ventral pattern formation GO: ~hindbrain development GO: ~kidney development GO: ~inner ear development GO: ~response to inorganic substance GO: ~angiogenesis GO: ~cell part morphogenesis GO: ~regulation of cell size GO: ~cell projection morphogenesis

36 GO: ~regulation of kinase activity GO: ~regulation of transferase activity GO: ~regulation of protein kinase activity GO: ~learning or memory GO: ~regulation of lipid metabolic process GO: ~myeloid cell differentiation GO: ~protein amino acid phosphorylation GO: ~regulation of peptidyl-tyrosine phosphorylation GO: ~spinal cord development GO: ~positive regulation of cell development GO: ~developmental growth GO: ~response to estradiol stimulus GO: ~regulation of myeloid cell differentiation GO: ~cell activation GO: ~locomotory behavior GO: ~striated muscle cell differentiation GO: ~response to cytokine stimulus GO: ~regulation of cell projection organization GO: ~positive regulation of growth GO: ~positive regulation of protein modification process GO: ~death GO: ~response to mechanical stimulus GO: ~neuron migration GO: ~female pregnancy GO: ~autonomic nervous system development GO: ~gut development GO: ~response to bacterium GO: ~cell differentiation in spinal cord GO: ~negative regulation of epithelial cell proliferation GO: ~diencephalon development GO: ~metanephros development GO: ~intracellular signaling cascade GO: ~neural tube development GO: ~development of primary sexual characteristics GO: ~placenta development GO: ~induction of apoptosis GO: ~induction of programmed cell death GO: ~sex differentiation GO: ~regulation of cell activation GO: ~regulation of smooth muscle cell proliferation GO: ~odontogenesis of dentine-containing tooth GO: ~cell death GO: ~regulation of cellular component size GO: ~response to ethanol GO: ~positive regulation of response to external stimulus GO: ~myeloid leukocyte differentiation GO: ~protein import into nucleus, translocation GO: ~cardiac cell differentiation GO: ~regulation of protein kinase cascade GO: ~regulation of homeostatic process

37 GO: ~ureteric bud development GO: ~ear morphogenesis GO: ~skeletal muscle tissue development GO: ~skeletal muscle organ development GO: ~hair follicle development GO: ~molting cycle process GO: ~hair cycle process GO: ~ectoderm development GO: ~ovulation cycle GO: ~molting cycle GO: ~hair cycle GO: ~regulation of cell morphogenesis involved in differentiation GO: ~negative regulation of multicellular organismal process GO: ~regulation of neurological system process GO: ~cell-cell signaling involved in cell fate specification GO: ~developmental induction GO: ~regulation of neuron projection development GO: ~cytokine-mediated signaling pathway GO: ~liver development GO: ~nerve development GO: ~negative regulation of cell cycle GO: ~positive regulation of transport GO: ~epidermis development GO: ~protein kinase cascade GO: ~regulation of DNA metabolic process GO: ~positive regulation of DNA metabolic process GO: ~programmed cell death GO: ~gliogenesis GO: ~regulation of survival gene product expression GO: ~neural tube patterning GO: ~in utero embryonic development GO: ~intracellular receptor-mediated signaling pathway GO: ~regulation of mitotic cell cycle GO: ~positive regulation of cell cycle GO: ~regulation of myeloid leukocyte differentiation GO: ~response to metal ion GO: ~phosphorylation GO: ~cell surface receptor linked signal transduction GO: ~positive regulation of protein kinase cascade GO: ~osteoblast differentiation GO: ~response to vitamin A GO: ~pituitary gland development GO: ~regulation of cell morphogenesis GO: ~pancreas development GO: ~eye development GO: ~positive regulation of response to stimulus GO: ~homeostasis of number of cells GO: ~negative regulation of response to stimulus GO: ~regulation of transmission of nerve impulse GO: ~negative regulation of transport

38 GO: ~induction of an organ GO: ~leukocyte activation GO: ~regulation of DNA replication GO: ~negative regulation of neurogenesis GO: ~positive regulation of lipid metabolic process GO: ~peptidyl-tyrosine phosphorylation GO: ~positive regulation of smooth muscle cell proliferation GO: ~spleen development GO: ~positive regulation of cell division GO: ~telencephalon development GO: ~regulation of cytokine production GO: ~ion homeostasis GO: ~negative regulation of cell development GO: ~peptidyl-tyrosine modification GO: ~regulation of cellular ketone metabolic process GO: ~positive regulation of specific transcription from RNA polymerase II prom GO: ~apoptosis GO: ~epithelial tube morphogenesis GO: ~neural crest cell differentiation GO: ~cell fate determination GO: ~positive regulation of myeloid cell differentiation GO: ~neural crest cell development GO: ~bone morphogenesis GO: ~cellular chemical homeostasis GO: ~regulation of fatty acid metabolic process GO: ~negative regulation of cell size GO: ~response to radiation GO: ~positive regulation of cell activation GO: ~regulation of synaptic transmission GO: ~gonad development GO: ~reproductive process in a multicellular organism GO: ~multicellular organism reproduction GO: ~female sex differentiation GO: ~development of primary female sexual characteristics GO: ~positive regulation of cell adhesion GO: ~regulation of muscle development GO: ~regulation of hormone levels GO: ~prostate gland development GO: ~inflammatory response GO: ~cellular ion homeostasis GO: ~positive regulation of DNA replication GO: ~response to vitamin D GO: ~regulation of leukocyte activation GO: ~rhythmic process GO: ~ovulation cycle process GO: ~glial cell differentiation GO: ~positive regulation of immune system process GO: ~positive regulation of organelle organization GO: ~regulation of epithelial cell differentiation GO: ~male sex differentiation

39 GO: ~heart morphogenesis GO: ~protein amino acid autophosphorylation GO: ~pallium development GO: ~blood circulation GO: ~circulatory system process GO: ~regulation of membrane potential GO: ~inner ear morphogenesis GO: ~positive regulation of kinase activity GO: ~regulation of secretion GO: ~regulation of cell division GO: ~positive regulation of peptidyl-tyrosine phosphorylation GO: ~negative regulation of growth GO: ~phosphorus metabolic process GO: ~phosphate metabolic process GO: ~regulation of cellular localization GO: ~regulation of axonogenesis GO: ~cardiac muscle tissue development GO: ~regulation of mesenchymal cell proliferation GO: ~positive regulation of myeloid leukocyte differentiation GO: ~regulation of oxidoreductase activity GO: ~cellular homeostasis GO: ~regulation of monooxygenase activity GO: ~positive regulation of protein kinase activity GO: ~positive regulation of neurogenesis GO: ~exocrine system development GO: ~regulation of striated muscle tissue development GO: ~positive regulation of B cell activation GO: ~response to retinoic acid GO: ~negative regulation of neuron differentiation GO: ~positive regulation of transferase activity GO: ~negative regulation of cell growth GO: ~negative regulation of cellular component organization GO: ~positive regulation of oxidoreductase activity GO: ~hindlimb morphogenesis GO: ~regulation of B cell activation GO: ~MAPKKK cascade GO: ~regulation of chondrocyte differentiation GO: ~Notch signaling pathway GO: ~response to progesterone stimulus GO: ~regulation of glial cell differentiation GO: ~regulation of cell-matrix adhesion GO: ~axon guidance GO: ~metencephalon development GO: ~fat cell differentiation GO: ~female gonad development GO: ~adult locomotory behavior GO: ~digestive tract morphogenesis GO: ~regulation of gliogenesis GO: ~digestive system development GO: ~regulation of JAK-STAT cascade

40 GO: ~neuron fate specification GO: ~cell maturation GO: ~negative regulation of signal transduction GO: ~development of primary male sexual characteristics GO: ~epithelial cell differentiation GO: ~di-, tri-valent inorganic cation homeostasis GO: ~regulation of cell-substrate adhesion GO: ~regulation of heart contraction GO: ~tissue remodeling GO: ~forelimb morphogenesis GO: ~regulation of developmental growth GO: ~endochondral bone morphogenesis GO: ~gland morphogenesis GO: ~interphase of mitotic cell cycle GO: ~lymphocyte differentiation GO: ~positive regulation of cell size GO: ~segmentation GO: ~defense response GO: ~cardiac muscle cell differentiation GO: ~forebrain regionalization GO: ~extracellular matrix organization GO: ~negative regulation of cell communication GO: ~gastrulation GO: ~positive regulation of mesenchymal cell proliferation GO: ~endocrine pancreas development GO: ~interphase GO: ~positive regulation of leukocyte activation GO: ~positive regulation of neuron differentiation GO: ~positive regulation of ossification GO: ~protein localization in nucleus GO: ~limbic system development GO: ~tissue regeneration GO: ~peptide secretion GO: ~positive regulation of epithelial cell proliferation GO: ~regulation of cellular catabolic process GO: ~regulation of multicellular organism growth GO: ~regulation of lymphocyte activation GO: ~extracellular structure organization GO: ~positive regulation of survival gene product expression GO: ~thyroid gland development GO: ~embryonic heart tube development GO: ~regulation of foam cell differentiation GO: ~endoderm development GO: ~post-embryonic development GO: ~positive regulation of cell growth GO: ~positive regulation of lymphocyte activation GO: ~multicellular organismal homeostasis GO: ~protein import into nucleus GO: ~regulation of osteoblast differentiation GO: ~transcription, DNA-dependent

41 GO: ~organ regeneration GO: ~positive regulation of JAK-STAT cascade GO: ~regulation of binding GO: ~regulation of synaptic plasticity GO: ~cartilage condensation GO: ~embryonic forelimb morphogenesis GO: ~T cell activation GO: ~induction of apoptosis by intracellular signals GO: ~regulation of cyclin-dependent protein kinase activity GO: ~regulation of inflammatory response GO: ~nuclear import GO: ~lymphocyte activation GO: ~regulation of fibroblast proliferation GO: ~dorsal spinal cord development GO: ~RNA biosynthetic process GO: ~regulation of cellular component biogenesis GO: ~negative regulation of phosphorylation GO: ~hormone secretion GO: ~regulation of organelle organization GO: ~positive regulation of cytokine production GO: ~positive regulation of cellular catabolic process GO: ~leukocyte homeostasis GO: ~positive regulation of carbohydrate metabolic process GO: ~positive regulation of cellular carbohydrate metabolic process GO: ~positive regulation of protein transport GO: ~calcium ion homeostasis GO: ~regulation of behavior GO: ~cation homeostasis GO: ~regulation of peptidyl-serine phosphorylation GO: ~cellular response to hormone stimulus GO: ~eye morphogenesis GO: ~feeding behavior GO: ~positive regulation of fatty acid metabolic process GO: ~steroid hormone receptor signaling pathway GO: ~morphogenesis of embryonic epithelium GO: ~positive regulation of chemotaxis GO: ~regulation of cellular carbohydrate metabolic process GO: ~camera-type eye development GO: ~negative regulation of gene-specific transcription GO: ~negative regulation of phosphorus metabolic process GO: ~negative regulation of phosphate metabolic process GO: ~regulation of carbohydrate metabolic process GO: ~peptide hormone secretion GO: ~positive regulation of catabolic process GO: ~hormone transport GO: ~carbohydrate homeostasis GO: ~glucose homeostasis GO: ~regulation of organ growth GO: ~positive regulation of inflammatory response GO: ~ureteric bud morphogenesis

42 GO: ~branching involved in ureteric bud morphogenesis GO: ~positive regulation of neuron apoptosis GO: ~regulation of epidermis development GO: ~oligodendrocyte differentiation GO: ~activation of pro-apoptotic gene products GO: ~thymus development GO: ~regulation of chemokine production GO: ~negative regulation of transferase activity GO: ~learning GO: ~regulation of leukocyte proliferation GO: ~regulation of mononuclear cell proliferation GO: ~response to light stimulus GO: ~regulation of protein localization GO: ~regulation of endocytosis GO: ~generation of a signal involved in cell-cell signaling GO: ~regulation of tyrosine phosphorylation of STAT protein GO: ~regulation of chemotaxis GO: ~apoptotic mitochondrial changes GO: ~induction of apoptosis by extracellular signals GO: ~adult behavior GO: ~regulation of coagulation GO: ~transcription from RNA polymerase II promoter GO: ~response to corticosterone stimulus GO: ~regulation of chemokine biosynthetic process GO: ~ventricular cardiac muscle cell differentiation GO: ~positive regulation of peptidyl-serine phosphorylation GO: ~negative regulation of protein kinase activity GO: ~response to insulin stimulus GO: ~response to organic nitrogen GO: ~regulation of angiogenesis GO: ~regulation of cell cycle process GO: ~brown fat cell differentiation GO: ~cellular response to extracellular stimulus GO: ~metal ion homeostasis GO: ~negative regulation of cell adhesion GO: ~T cell differentiation GO: ~regulation of transcription factor activity GO: ~gut morphogenesis GO: ~negative regulation of kinase activity GO: ~peptide transport GO: ~epidermis morphogenesis GO: ~positive regulation of osteoblast differentiation GO: ~positive regulation of multicellular organism growth GO: ~somitogenesis GO: ~regulation of glucose transport GO: ~positive regulation of behavior GO: ~regulation of cardiac muscle cell proliferation GO: ~regulation of cardiac muscle tissue development GO: ~cranial nerve morphogenesis GO: ~regulation of cardiac muscle growth

43 GO: ~regulation of cholesterol storage GO: ~pons development GO: ~cartilage development involved in endochondral bone morphogenesis GO: ~negative regulation of cholesterol storage GO: ~enteric nervous system development GO: ~rostrocaudal neural tube patterning GO: ~cellular di-, tri-valent inorganic cation homeostasis GO: ~response to oxidative stress GO: ~anatomical structure homeostasis GO: ~regulation of glucose metabolic process GO: ~positive regulation of protein complex assembly GO: ~positive regulation of leukocyte proliferation GO: ~G1/S transition of mitotic cell cycle GO: ~positive regulation of mononuclear cell proliferation GO: ~embryonic hindlimb morphogenesis GO: ~embryonic cranial skeleton morphogenesis GO: ~peptidyl-threonine phosphorylation GO: ~regulation of immunoglobulin production GO: ~positive regulation of angiogenesis GO: ~regulation of lipid catabolic process GO: ~leukocyte migration GO: ~cellular calcium ion homeostasis GO: ~regulation of MAPKKK cascade GO: ~regulation of nitric oxide biosynthetic process GO: ~insulin secretion GO: ~T cell differentiation in the thymus GO: ~positive regulation of cell projection organization GO: ~regulation of vesicle-mediated transport GO: ~regulation of catabolic process GO: ~negative regulation of foam cell differentiation GO: ~positive regulation of vasodilation GO: ~regulation of heart growth GO: ~positive regulation of microtubule polymerization GO: ~salivary gland development GO: ~hair follicle morphogenesis GO: ~cranial nerve development GO: ~positive regulation of glucose metabolic process GO: ~neuron apoptosis GO: ~regulation of lymphocyte proliferation GO: ~response to temperature stimulus GO: ~ameboidal cell migration GO: ~cellular cation homeostasis GO: ~regulation of MAP kinase activity GO: ~regulation of anti-apoptosis GO: ~response to mineralocorticoid stimulus GO: ~regulation of vasodilation GO: ~somatic stem cell division GO: ~rhombomere development GO: ~regulation of calcidiol 1-monooxygenase activity GO: ~spinal cord association neuron differentiation

44 GO: ~positive regulation of chemokine biosynthetic process GO: ~salivary gland morphogenesis GO: ~nuclear transport GO: ~regulation of peptidase activity GO: ~response to toxin GO: ~positive regulation of monooxygenase activity GO: ~middle ear morphogenesis GO: ~decidualization GO: ~positive regulation of microtubule polymerization or depolymerization GO: ~spinal cord motor neuron differentiation GO: ~regulation of microtubule polymerization GO: ~regulation of respiratory gaseous exchange GO: ~hair follicle maturation GO: ~retinoic acid receptor signaling pathway GO: ~JAK-STAT cascade GO: ~regulation of muscle cell differentiation GO: ~memory GO: ~mesoderm development GO: ~taxis GO: ~chemotaxis GO: ~regulation of immune effector process GO: ~response to reactive oxygen species GO: ~protein localization in organelle GO: ~positive regulation of nitric oxide biosynthetic process GO: ~peptidyl-threonine modification GO: ~regulation of carbohydrate biosynthetic process GO: ~release of cytochrome c from mitochondria GO: ~regulation of long-term neuronal synaptic plasticity GO: ~T cell homeostasis GO: ~positive regulation of MAP kinase activity GO: ~regulation of bone mineralization GO: ~negative regulation of molecular function GO: ~tissue homeostasis GO: ~cell cycle arrest GO: ~transmembrane receptor protein serine/threonine kinase signaling pathw GO: ~cellular metal ion homeostasis GO: ~male gonad development GO: ~regulation of production of molecular mediator of immune response GO: ~vasculogenesis GO: ~negative regulation of specific transcription from RNA polymerase II prom GO: ~dorsal/ventral neural tube patterning GO: ~organ growth GO: ~mating behavior GO: ~lung alveolus development GO: ~regulation of proteolysis GO: ~regulation of myeloid cell apoptosis GO: ~parasympathetic nervous system development GO: ~regulation of fatty acid beta-oxidation GO: ~positive regulation of fatty acid oxidation GO: ~growth hormone receptor signaling pathway

45 GO: ~regulation of odontogenesis GO: ~endoplasmic reticulum calcium ion homeostasis GO: ~macrophage differentiation GO: ~ensheathment of neurons GO: ~axon ensheathment GO: ~response to camp GO: ~regulation of DNA binding GO: ~regulation of establishment of protein localization GO: ~palate development GO: ~response to osmotic stress GO: ~negative regulation of protein amino acid phosphorylation GO: ~regulation of biomineral formation GO: ~regulation of caspase activity GO: ~membrane organization GO: ~regulation of epidermal growth factor receptor signaling pathway GO: ~neural crest cell migration GO: ~positive regulation of tyrosine phosphorylation of STAT protein GO: ~regulation of epidermal growth factor receptor activity GO: ~maternal placenta development GO: ~ventral spinal cord development GO: ~positive regulation of lymphocyte proliferation GO: ~regulation of glucose import GO: ~cerebral cortex development GO: ~cell aging GO: ~positive regulation of secretion GO: ~nucleocytoplasmic transport GO: ~muscle cell development GO: ~regulation of endopeptidase activity GO: ~response to acid GO: ~regulation of lipid biosynthetic process GO: ~response to glucose stimulus GO: ~cell junction organization GO: ~lung epithelium development GO: ~response to lipoprotein stimulus GO: ~regulation of cardioblast differentiation GO: ~positive regulation of cardioblast differentiation GO: ~JAK-STAT cascade involved in growth hormone signaling pathway GO: ~positive regulation of I-kappaB kinase/nf-kappab cascade GO: ~positive regulation of epidermis development GO: ~somatic stem cell maintenance GO: ~sprouting angiogenesis GO: ~anagen GO: ~response to growth hormone stimulus GO: ~stem cell division GO: ~midbrain development GO: ~myeloid leukocyte activation GO: ~positive regulation of protein polymerization GO: ~positive regulation of mitosis GO: ~positive regulation of nuclear division GO: ~stem cell maintenance

46 GO: ~embryonic digit morphogenesis GO: ~behavioral interaction between organisms GO: ~regulation of protein transport GO: ~response to UV GO: ~response to hexose stimulus GO: ~response to monosaccharide stimulus GO: ~negative regulation of protein kinase cascade GO: ~regulation of blood coagulation GO: ~regulation of neuronal synaptic plasticity GO: ~mesoderm formation GO: ~peripheral nervous system development GO: ~regulation of organic acid transport GO: ~protein import GO: ~stem cell development GO: ~positive regulation of fibroblast proliferation GO: ~positive regulation of defense response GO: ~response to ionizing radiation GO: ~response to carbohydrate stimulus GO: ~positive regulation of MAPKKK cascade GO: ~B cell differentiation GO: ~positive regulation of cytokine biosynthetic process GO: ~regulation of T cell activation GO: ~positive regulation of glial cell differentiation GO: ~epithelial cell proliferation GO: ~osteoblast development GO: ~negative regulation of organic acid transport GO: ~regulation of cytokine biosynthetic process GO: ~regulation of cellular response to stress GO: ~chondrocyte differentiation GO: ~regulation of erythrocyte differentiation GO: ~lipid storage GO: ~epithelial to mesenchymal transition GO: ~reproductive behavior GO: ~regulation of receptor activity GO: ~negative regulation of cytokine production GO: ~mesoderm morphogenesis GO: ~myelination GO: ~regulation of lymphocyte differentiation GO: ~lactation GO: ~lymphocyte homeostasis GO: ~negative regulation of cell projection organization GO: ~regulation of fatty acid oxidation GO: ~cell-cell adhesion GO: ~hormone metabolic process GO: ~cell chemotaxis GO: ~response to amine stimulus GO: ~multicellular organismal response to stress GO: ~regulation of T cell differentiation GO: ~development of secondary sexual characteristics GO: ~healing during inflammatory response

47 GO: ~midbrain-hindbrain boundary development GO: ~midgut development GO: ~forebrain neuron fate commitment GO: ~negative regulation of chondrocyte differentiation GO: ~regulation of odontogenesis of dentine-containing tooth GO: ~mitochondrion organization GO: ~positive regulation of gliogenesis GO: ~keratinocyte proliferation GO: ~regulation of mitochondrial membrane permeability GO: ~negative regulation of cell-substrate adhesion GO: ~vascular endothelial growth factor receptor signaling pathway GO: ~tongue development GO: ~membrane protein intracellular domain proteolysis GO: ~regulation of I-kappaB kinase/nf-kappab cascade GO: ~fibroblast growth factor receptor signaling pathway GO: ~mechanoreceptor differentiation GO: ~acute-phase response GO: ~formation of primary germ layer GO: ~regulation of hydrolase activity GO: ~protein oligomerization GO: ~regulation of hormone secretion GO: ~regulation of blood vessel size GO: ~regulation of tube size GO: ~immune response GO: ~positive regulation of protein secretion GO: ~regulation of leukocyte migration GO: ~membrane protein proteolysis GO: ~embryo implantation GO: ~regulation of lipid transport GO: ~positive regulation of intracellular transport GO: ~positive regulation of anti-apoptosis GO: ~regulation of generation of precursor metabolites and energy GO: ~activation of caspase activity GO: ~regulation of action potential in neuron GO: ~germ cell migration GO: ~neuron projection regeneration GO: ~negative regulation of lipid storage GO: ~positive regulation of phosphoinositide 3-kinase cascade GO: ~embryonic gut development GO: ~C21-steroid hormone metabolic process GO: ~embryonic eye morphogenesis GO: ~regulation of microtubule cytoskeleton organization GO: ~cellular response to insulin stimulus GO: ~regulation of microtubule polymerization or depolymerization GO: ~negative regulation of secretion GO: ~response to calcium ion GO: ~positive regulation of hydrolase activity GO: ~positive regulation of lipid biosynthetic process GO: ~regulation of lipid storage GO: ~negative regulation of immune system process

48 GO: ~determination of symmetry GO: ~determination of bilateral symmetry GO: ~activation of protein kinase activity GO: ~response to hydrogen peroxide GO: ~regulation of mitosis GO: ~regulation of nuclear division GO: ~regulation of ion transport GO: ~paraxial mesoderm formation GO: ~regulation of hair cycle GO: ~dopamine biosynthetic process GO: ~spinal cord motor neuron cell fate specification GO: ~regulation of hair follicle development GO: ~tyrosine phosphorylation of STAT protein GO: ~regulation of endothelial cell proliferation GO: ~regulation of striated muscle cell differentiation GO: ~stem cell differentiation GO: ~transmission of nerve impulse GO: ~leukocyte proliferation GO: ~mononuclear cell proliferation GO: ~regulation of membrane protein ectodomain proteolysis GO: ~regulation of phosphoinositide 3-kinase cascade GO: ~regulation of tyrosine phosphorylation of Stat5 protein GO: ~regulation of blood pressure GO: ~regulation of cell-cell adhesion GO: ~heart looping GO: ~regulation of osteoclast differentiation GO: ~hippocampus development GO: ~negative regulation of mitotic cell cycle GO: ~endothelial cell migration GO: ~membrane invagination GO: ~endocytosis GO: ~DNA damage response, signal transduction resulting in induction of apop GO: ~vascular process in circulatory system GO: ~regulation of protein secretion GO: ~negative regulation of catalytic activity GO: ~regulation of muscle contraction GO: ~positive regulation of translation GO: ~negative regulation of ion transport GO: ~blood vessel remodeling GO: ~genitalia development GO: ~cellular hormone metabolic process GO: ~positive regulation of peptidase activity GO: ~positive regulation of caspase activity GO: ~regulation of Wnt receptor signaling pathway GO: ~regulation of glucan biosynthetic process GO: ~regulation of polysaccharide biosynthetic process GO: ~regulation of glycogen biosynthetic process GO: ~response to salt stress GO: ~positive regulation of transcription factor activity GO: ~muscle fiber development

49 GO: ~cell-cell junction organization GO: ~regulation of synapse structure and activity GO: ~embryonic placenta development GO: ~cell growth GO: ~negative regulation of cell activation GO: ~regulation of leukocyte mediated immunity GO: ~positive regulation of protein import into nucleus, translocation GO: ~preganglionic parasympathetic nervous system development GO: ~cardiac muscle tissue growth GO: ~striated muscle cell proliferation GO: ~heart growth GO: ~regulation of fibroblast growth factor receptor signaling pathway GO: ~regulation of retinal cell programmed cell death GO: ~glial cell fate commitment GO: ~cardiac muscle cell proliferation GO: ~senescence GO: ~positive regulation of T cell activation GO: ~response to protein stimulus GO: ~regulation of interleukin-6 production GO: ~negative regulation of lipid transport GO: ~regulation of polysaccharide metabolic process GO: ~regulation of dendrite development GO: ~generation of neurons in the forebrain GO: ~membrane protein ectodomain proteolysis GO: ~negative regulation of endocytosis GO: ~central nervous system neuron axonogenesis GO: ~response to X-ray GO: ~neurological system process GO: ~negative regulation of axonogenesis GO: ~regulation of skeletal muscle fiber development GO: ~erythrocyte homeostasis GO: ~regulation of microtubule-based process GO: ~negative regulation of cell motion GO: ~leukocyte chemotaxis GO: ~negative regulation of catabolic process GO: ~biomineral formation GO: ~negative regulation of response to external stimulus GO: ~glial cell development GO: ~reproductive cellular process GO: ~positive regulation of developmental growth GO: ~lipid homeostasis GO: ~hypothalamus development GO: ~response to magnesium ion GO: ~positive regulation of cyclin-dependent protein kinase activity GO: ~regulation of muscle cell apoptosis GO: ~SMAD protein nuclear translocation GO: ~positive regulation of chondrocyte differentiation GO: ~negative regulation of epithelial cell differentiation GO: ~regulation of platelet activation GO: ~sleep

50 GO: ~paraxial mesoderm morphogenesis GO: ~neural nucleus development GO: ~cellular response to stress GO: ~striated muscle cell development GO: ~protein heterooligomerization GO: ~mating GO: ~negative regulation of DNA metabolic process GO: ~peptidyl-serine modification GO: ~biological adhesion GO: ~cell adhesion GO: ~regulation of smoothened signaling pathway GO: ~regulation of interleukin-12 production GO: ~negative regulation of MAPKKK cascade GO: ~regulation of tyrosine phosphorylation of Stat3 protein GO: ~regulation of multicellular organismal metabolic process GO: ~secretion GO: ~regulation of insulin secretion GO: ~central nervous system neuron differentiation GO: ~positive regulation of cell-substrate adhesion GO: ~negative regulation of lipid metabolic process GO: ~epidermal growth factor receptor signaling pathway GO: ~regulation of action potential GO: ~regulation of lymphocyte mediated immunity GO: ~response to alkaloid GO: ~regulation of stress-activated protein kinase signaling pathway GO: ~regulation of vascular endothelial growth factor production GO: ~regulation of oligodendrocyte differentiation GO: ~muscle cell proliferation GO: ~positive regulation of cell-matrix adhesion GO: ~embryonic hemopoiesis GO: ~insulin-like growth factor receptor signaling pathway GO: ~regulation of protein import into nucleus, translocation GO: ~response to fluid shear stress GO: ~activation of caspase activity by cytochrome c GO: ~response to lipid GO: ~neutrophil chemotaxis GO: ~regulation of synaptogenesis GO: ~positive regulation of bone mineralization GO: ~germ cell development GO: ~regulation of adaptive immune response based on somatic recombinatio GO: ~collagen fibril organization GO: ~regulation of skeletal muscle tissue development GO: ~peptidyl-serine phosphorylation GO: ~positive regulation of DNA binding GO: ~determination of left/right symmetry GO: ~response to starvation GO: ~lymphocyte proliferation GO: ~regulation of adaptive immune response GO: ~creatinine metabolic process GO: ~positive regulation of calcidiol 1-monooxygenase activity

51 GO: ~development of secondary female sexual characteristics GO: ~regulation of gastrulation GO: ~oligodendrocyte cell fate commitment GO: ~spinal cord oligodendrocyte cell differentiation GO: ~glial cell fate specification GO: ~oligodendrocyte cell fate specification GO: ~organ formation GO: ~inflammatory cell apoptosis GO: ~regulation of heterotypic cell-cell adhesion GO: ~negative regulation of phagocytosis GO: ~luteinization GO: ~spinal cord oligodendrocyte cell fate specification GO: ~regulation of cell-cell adhesion involved in gastrulation GO: ~response to UV-A GO: ~lacrimal gland development GO: ~rhombomere 4 development GO: ~cerebellum development GO: ~negative regulation of myeloid cell differentiation GO: ~regulation of chromosome organization GO: ~embryonic epithelial tube formation GO: ~blastocyst development GO: ~membrane depolarization GO: ~negative regulation of cell migration GO: ~positive regulation of cyclase activity GO: ~regulation of insulin receptor signaling pathway GO: ~platelet-derived growth factor receptor signaling pathway GO: ~positive regulation of interleukin-6 production GO: ~positive regulation of biomineral formation GO: ~sex determination GO: ~fear response GO: ~Ras protein signal transduction GO: ~regulation of nucleocytoplasmic transport GO: ~regulation of T-helper 2 type immune response GO: ~positive regulation of glycogen biosynthetic process GO: ~ectodermal gut morphogenesis GO: ~axon regeneration GO: ~lymphocyte apoptosis GO: ~positive regulation of epithelial cell differentiation GO: ~negative regulation of cell-matrix adhesion GO: ~ectodermal gut development GO: ~positive regulation of tyrosine phosphorylation of Stat5 protein GO: ~negative regulation of glucose transport GO: ~positive regulation of leukocyte chemotaxis GO: ~receptor metabolic process GO: ~BMP signaling pathway GO: ~cellular response to nutrient levels GO: ~tube lumen formation GO: ~protein complex biogenesis GO: ~protein complex assembly GO: ~regulation of protein complex assembly

52 GO: ~positive regulation of lyase activity GO: ~dopamine metabolic process GO: ~response to axon injury GO: ~negative regulation of cellular catabolic process GO: ~blastocyst formation GO: ~positive regulation of cytoskeleton organization GO: ~sensory perception of pain GO: ~mitochondrial membrane organization GO: ~central nervous system neuron development GO: ~positive regulation of T cell differentiation GO: ~negative regulation of cellular protein metabolic process GO: ~synaptic transmission GO: ~regulation of peptide secretion GO: ~B cell activation GO: ~negative regulation of locomotion GO: ~positive regulation of stress-activated protein kinase signaling pathway GO: ~regulation of synapse organization GO: ~response to cold GO: ~bone remodeling GO: ~negative regulation of homeostatic process GO: ~fat-soluble vitamin metabolic process GO: ~positive regulation of lipid transport GO: ~regulation of keratinocyte differentiation GO: ~regulation of pigmentation during development GO: ~positive regulation of tyrosine phosphorylation of Stat3 protein GO: ~regulation of leukocyte chemotaxis GO: ~hemopoietic progenitor cell differentiation GO: ~cerebral cortex neuron differentiation GO: ~catecholamine biosynthetic process GO: ~negative regulation of cyclin-dependent protein kinase activity GO: ~negative regulation of gliogenesis GO: ~lipopolysaccharide-mediated signaling pathway GO: ~regulation of mitochondrial membrane potential GO: ~regulation of collagen biosynthetic process GO: ~negative regulation of glial cell differentiation GO: ~regulation of macrophage differentiation GO: ~regulation of cyclic nucleotide biosynthetic process GO: ~regulation of nucleotide biosynthetic process GO: ~regulation of T cell proliferation GO: ~microtubule cytoskeleton organization GO: ~positive regulation of binding GO: ~positive regulation of synaptic transmission GO: ~positive regulation of glucose import GO: ~positive regulation of glucose transport GO: ~regulation of protein heterodimerization activity GO: ~positive regulation of hair follicle development GO: ~cranial nerve structural organization GO: ~telencephalon regionalization GO: ~negative regulation of calcium ion transport into cytosol GO: ~forebrain dorsal/ventral pattern formation

53 GO: ~regulation of cyclin-dependent protein kinase activity during G1/S GO: ~isoleucine metabolic process GO: ~menstrual cycle phase GO: ~transformed cell apoptosis GO: ~rhombomere 3 development GO: ~positive regulation of cyclin-dependent protein kinase activity during G1/ GO: ~facial nerve morphogenesis GO: ~allantoin metabolic process GO: ~regulation of plasma membrane long-chain fatty acid transport GO: ~smooth muscle adaptation GO: ~response to folic acid GO: ~low-density lipoprotein particle clearance GO: ~negative regulation of plasma membrane long-chain fatty acid transport GO: ~positive regulation of necrotic cell death GO: ~facial nerve structural organization GO: ~regulation of cyclic nucleotide metabolic process GO: ~muscle system process GO: ~negative regulation of protein metabolic process GO: ~positive regulation of lymphocyte differentiation GO: ~secretion by cell GO: ~DNA damage response, signal transduction GO: ~negative regulation of calcium ion transport GO: ~response to iron ion GO: ~positive regulation of mitotic cell cycle GO: ~regulation of collagen metabolic process GO: ~endochondral ossification GO: ~nitric oxide biosynthetic process GO: ~pathway-restricted SMAD protein phosphorylation GO: ~paraxial mesoderm development GO: ~response to gamma radiation GO: ~regulation of metal ion transport GO: ~regulation of JNK cascade GO: ~regulation of steroid metabolic process GO: ~androgen receptor signaling pathway GO: ~cell activation during immune response GO: ~leukocyte activation during immune response GO: ~regulation of nucleotide metabolic process GO: ~activation of MAPK activity GO: ~posttranscriptional regulation of gene expression GO: ~positive regulation of transmission of nerve impulse GO: ~insulin receptor signaling pathway GO: ~cytosolic calcium ion homeostasis GO: ~regulation of histone modification GO: ~positive regulation of multicellular organismal metabolic process GO: ~nitric oxide metabolic process GO: ~response to tumor necrosis factor GO: ~motor axon guidance GO: ~regulation of isotype switching GO: ~positive regulation of coagulation GO: ~positive regulation of lipid catabolic process