The World s fastest OCT. As simple as pressing. the start button

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1 The World s fastest OCT As simple as pressing the start button

2 lution continues Optopol engineering team, designers of the first commercially available Spectral Domain OCT in the world, are proud to present the World s fastest OCT. Our supreme experience in Spectral Domain OCT allows us to provide the market with the state of the art instrument, offering advanced technologies and remarkable simplicity of operation. The new REVO NX software meets all demands of a daily routine in a modern ophthalmic practice. The new angiography module expands the precision of your diagnosis with minimum patient fatigue. Need for speed The world s fastest available scanning speed allows for more achievable and more detailed exams with reduction of the scanning time. It brings benefits for both clinicians and patients by reducing errors often caused by involuntary eye movements. OCT made simple as never before Position the patient and press the START button to acquire examinations of both eyes. The Revo NX, using vocal messages, guides the patient through the process, increasing comfort and reducing patient chair time. Short scanning time ensures less fatigue for the patient. Creating customized scanning protocols of different diagnostic scenarios speed s up the workflow. A perfect fit for every practice. With a small system footprint and access for both operator and patient only necessary from one side, space saving is further enhanced. In addition, connection by a single cable allows the installation of REVO NX into the smallest of examination room spaces. Revo s variety of examination and analysis tools enables it to effortlessly function as a screening or advanced diagnostic device. High quality of OCT image The noise reduction technology provides the finest details proven to be important for early disease detection.

3 offers the newest standards available in OCT technology ANGIOGRAPHY SOCT* This non-invasive dye free technique allows the visualization of the microvasculature of the retina. Both blood flow and structural visualization will give additional information in the diagnosis of many retinal diseases. Angiography scan allows assessment of the structural vasculature of the macula, periphery or the optic disc. Extremely short scanning time 1.6 second in standard resolution or in high resolution within ~3 seconds. Superficial plexus Deep Plexus Optic Nerve Head Peripheral area Now Angiography OCT can become a routine diagnosis in your practice. RETINA A single 3D macula scan performs both Retina and Glaucoma analysis.the software automatically recognizes 8 retinal layers which assists with a precise diagnosis and the mapping of any changes in the patient s condition. A variety of result analysis and presentation methods allows for the best selection suitable to increase efficiency of work. Single Comparison Both Progression WIDEFIELD SCAN 12x12 mm Widefield Central scan is perfect for fast and precise screening of the patient s retina. Dense scanning in high resolution tomograms guarantee the discovery of most of the early changes. Peripheral scanning reveals diseases in the far periphery. * SOCT Angio is an optional software module to purchase. Combined view of two examinations of peripheral scan 12 mm + 12 mm. Done in external software.

4 GLAUCOMA Comprehensive glaucoma analysis tools for quantification of the Nerve Fiber Layer, Ganglion layer and Optic Head with DDLS allows for precise diagnosis and the monitoring of glaucoma over time. Asymmetry Analysis of Ganglion layers between hemispheres and between eyes allows easier identification and detection of glaucoma in early stages and in non-typical patients. ONH Both GCL+IPL Both ONH Progression GCL+IPL Progression ANTERIOR For a standard anterior examination, no additional lens is required. This allows the examiner to quickly complete the scanning procedure. Presentation of results for both eyes allows quick and precise evaluation of the condition of the anterior segment. Cornea Both Angle Both Additional adapter provided with the device increases range of clinical application in Anterior chamber observation. FOLLOW UP Revo s standard high density scanning capability and blood vessel structure recognition enable a precise alignment of past and current scans The Operator can analyze changes is morphology, quantified progression maps and evaluate the progression trends. Progression Morphology Progression Quantification DICOM, EMR, NETWORK INTEGRATION A proficient networking solution increases productivity and enhances the patient experience. It allows you to view and manage multiple examinations from review stations in your practice. Effortlessly helping to facilitate patient education by allowing you to interactively show examination results to patients. Every practice will have different requirements which we can provide by tailoring a bespoke service. DICOM connectivity allows the connection of the REVO into large hospital medical systems. Receive the Worklist (MWL) and send report (C-storage) or whole exam into view stations. CMDL interface allows for the integration of the REVO in to practice management systems. There is no additional charge for the networking and DICOM functionality.

5 Clinical images CNV BRVO GA Choroidal observation Central 12 mm scan Angle to Angle scan

6 t e c h n i c a l S p e c i f i c at i o n Technology Spectral Domain OCT Light Source SLED, Wavelength 830 nm Bandwidth 50 nm half bandwidth Scanning speed measurements per second Axial resolution 5 μm in tissue 2,6 μm digital Transverse Resolution 12 μm, typical 18 μm Overall scan depth 2.4 mm Min. pupil size 3 mm Focus adjustment range -25 D to +25 D Scan range Posterior 5-12 mm, Angio 3-9 mm, Anterior 3-16 mm Scan types 3D, Angio*, Radial (HD), B-scan (HD), Raster (HD), Cross (HD) Fundus image Live Fundus Reconstruction Alignment method Fully automatic, Automatic Retina analysis Retina thickness, Inner retinal thickness, Outer retinal thickness RNFL+GCL+IPL thickness, GCL+IPL thickness, RNFL thickness, RPE deformation, IS/OS thickness Angiography OCT* Superficial plexus, Deep Plexus, Outer Retina, Choriocapilaries, Depth Coded, Custom, Enface, Thickness map Glaucoma analysis RNFL, ONH morphology, DDLS, OU and Hemisphere asymmetry, Ganglion analysis as RNFL+GCL+IP and GCL+IPL Anterior Pachymetry, LASIK flap, Angle Assessment, AIOP, AOD 500/750, TISA 500/750 Anterior Wide Scan Angle to Angle view (Adapter required) Connectivity DICOM Storage SCU, DICOM MWL SCU, CMDL, Networking Dimensions (WxDxH) 382 x mm Weight 23 kg Fixation target OLED display (The target shape and position can be changed), External fixation arm Power supply V, 50/60 Hz Power consumption VA OPTOPOL Technology Sp. z o. o. ul. Żabia 42, Zawiercie, Poland Tel/Fax: info@optopol.com.pl ver. REVO NX

7 Biometry OCT in SOCT software 8.0 version

8 Biometry OCT Biometry OCT Innovative method of using the posterior OCT device to measure ocular structure along eye axis. OCT-B based on measurements of the mutual position of individual eye elements. The Eye elements are measured individually. System captures separate exams and measures distances between structures of eye elements.

9 Biometry OCT OCT Biometry provides: AL Axial Length SD +/ mm ACD Anterior chamber depth SD +/ mm LT Lens thickness SD +/ mm CCTCornea thickness SD +/- 6 um Axial Length ACD LT CCT

10 Biometry OCT 2 Biometry programs: AL AL.,CCT, ACD, LT parameter ACD CCT, ACD parameter Acquisition method: Full Auto Auto Number of repeats 5, 10, 15 Acquisition time 5 AL. full measurements ~ 4 sec

11 Analysis Single view Biometry OCT Both eyes view Result review window Single view and Both View Results table Result verification Excluding deviated results AVG and SD for measurements series

12 Biometry OCT Analysis Verification and correction Full screen view Precise review of each measurement Manual correction of boundaries Echogram or precise manual alignment

13 Biometry OCT Biometrical measurement sample cases Healthy Cataract Dense cataract still manual measurement is possible

14 Biometry OCT Clinical use Axial distances measurement UBM verification AL in monitoring Hi myopic eyes ACD management of glaucoma Benefits Extends the use of Standard OCT OCT Biometry provides exact measured boundaries of ocular structures Manual correction of boundaries which is not available in Gold standard Verification and precise correction for non typical cases Precise IOL detection for pseudo phakic eyes Limits Slightly lower penetration of dense cataract patient than newest SS optical biometers with 1050 nm wavelength

15 Biometry OCT Male, 37 y/old Healthy Healthy subject with visible peak in the vitrous behind the crystalline lens Berger space and vitrous

16 Biometry OCT Male, 24 y/old Healthy Patient with contact lens on the cornea Only REVO is able provide correct measurement. All other devices cannot detect the lens.

17 Biometry OCT Female, 67 y. Cataract

18 Biometry OCT Female, 40 y/old Cataract over posterior lens capsule

19 B-OCT Verification Female, 68 y. Patient with Macular hole after PPV treatment IOL 700 LT measurement error

20 B-OCT Verification IOL 700 REVO NX AL [mm] 27,16 27,16 ACD [mm] 4,13 4,16 LT [mm] 3,83 3,80 CCT [mm] 0,674 0,666 Patient: Male, 40 y. Contact lens on the cornea, myopic patient. In REVO NX it is possible to modified detected boundary position In IOL it is not possible to modify detected boundaries.

21 B-OCT Verification IOL 700 REVO NX AL [mm] 23,27 23,27 ACD [mm] 3,58 3,57 LT [mm] 4,22 4,22 CCT [mm] 0,583 0,587 Female, 50 y. Healthy

22 B-OCT Verification IOL 700 REVO NX AL [mm] 23,50 23,50 ACD [mm] 3,67 3,66 LT [mm] 4,86 4,93 CCT [mm] 0,519 0,515 Patient: Male, 72 y. Cataract

23 B-OCT Verification IOL 700 REVO NX AL [mm] 21,94 22,03 ACD [mm] 2,81 2,98 LT [mm] 3,99 3,92 CCT [mm] 0,559 0,599 Female, 31 y. Healthy

24 B-OCT Verification? IOL 700 REVO NX AL [mm] 28,94 29,17 ACD [mm] 3,49 3,54 LT [mm] 4,15 4,00 CCT [mm] 0,567 0,586 Patient: Female, 55 y. Cataract The biggest difference in comaparison study IOL does not show detected boundaries Long eye ball AL~29mm

25

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