Modeling the muscular response to motor neuron spike-trains. Laura Miller and Katie Newhall SAMSI Transition Workshop May 4, 2016
|
|
- Lee Green
- 5 years ago
- Views:
Transcription
1 Modeling the muscular response to motor neuron spike-trains Laura Miller and Katie Newhall SAMSI Transition Workshop May 4, 2016
2 Outline 1. Motivation for an integrative neural and mechanical view of animal locomotion and behavior. 2. Preview of the specific examples we considered. 3. Background on the biology and mathematical modeling of muscle. 4. How motor neuron spike trains result in muscle force generation: Biology and modeling. 5. Improvements to an integrative mathematical model.
3 Beyond Brains Call for integrated view of neural and biomechanical basis of behavior - Michael Dickinson, 2010 Allen Institute for Brain Science Symposium.
4 Applications Prosthetics and robots Goals: To understand how people adapt to robotic exoskeletons and bionic prostheses with the intent of improving technologies for rehabilitation Restore lost function for disabled patients by designing prosthetic devices that can translate neural brain activity
5 Applications
6 Applications and Data Available Gait analysis and pathological gaits
7 An Integrated View of Neuromechanics Example: Fish Swimming
8 Integrated Model from Tytell, Williams, et al. Credit: Eric D. Tytell, Tufts University
9 From Neuron Signals to Locomotion How does a jellyfish translate a neural signal into a swimming mode? How do phenomena such as muscle force-length relations and muscle stiffness affect swimming performance? How does a jellyfish adjust its behavior to maneuver or turn?
10 From Neuron Signals to Locomotion Model of insect walking Goal: Replace applied external force function in peg leg model with a model of the muscle. Future: Can we then integrate motor neuron activity to control walking? Philip Holmes, Robert J. Full, Dan Koditschek, and John Guckenheimer, SIAM Review, 2006
11 Muscle Activation Motor neuron signal - spike train. Action potentials along muscle cell. Release of Calcium ions from the SR. Calcium binding to troponin - regulates crossbridge formation. Myosin heads complete crossbridge cycle, myosin slides past actin. Muscle shortens and force is generated.
12 Spike Train to Force Dynamics In tetanic (full) contraction, spike trains are fast enough that the muscle does not relax between contractions. At lower frequencies, the muscle will relax between successive stimuli, and the tension produced will vary in time.
13 Sliding Filament Model: Muscle Contraction Thick filaments (myosin) slide across thin filaments (actin). Myosin heads burn ATP while forming crossbridges that pull on the actin. The instantaneous force of contraction depends on the instantaneous velocity. The force of contraction also depends on the current length of the muscle.
14 Hill Model: Force-Velocity Relationship The Hill muscle model describes the force-velocity relationship is for tetanic (fully activated) contraction. This is a steady state model in which the constants, a and b, are experimentally derived. Vmax = maximum velocity under no load P0 = Maximum load with no contraction Constants can be related to crossbridge dynamics.
15 Length-Tension Relationship At intermediate lengths, all of the myosin heads are within reach of the thin filaments. When stretched, few myosin heads overlap with the thin filaments. When fully contracted, interference reduces force.
16 Force-Velocity-Length Model Assume that the force produced for a given length, LF, and velocity may, VF, be found by multiplying the normalized Hill and Force-Velocity models. First rearrange terms and normalize: Force-Length Model Force-Velocity Model
17 2-Element Hill Muscle Model CE - contractile element SE - series element (nonlinear spring) lc - length contractile element vc - velocity contractile element Force generated by muscle is a function of activation strength, current length, lc, and current contractile velocity, vc. Contractile element is attached to a spring representing the tendon and connective tissues (resists long extensions).
18 Calcium Dynamics Model uses law of mass action to model the rates that calcium ions are bound and released from the actin filaments and the sarcoplasmic reticulum. Sarcoplasmic Reticulum (SR) Actin Filament
19 Williams Model [c] Free Calcium [cs] Calcium bound to SR [s] Free binding sites in SR [cf] Calcium bound to Filament [f] Free binding sites on Filament Williams, T.L. J Exp Bio 213, (2010)
20 Williams Model Reduction Total Calcium Ions Total SR binding sites Total filament binding sites 5 Unknowns, 3 Constraints, Reduce to 2 variables: Stimulus ON Stimulus OFF
21 Our Modification to Williams Model (1) (2) (3) Caf unbinding only proportional to number bound calcium Ca uptake to SR always present Release rate of calcium from SR function of time to model spike activation
22 Bifurcation Diagram Modification changes fixed points, choose new C, S parameters (1) Want (0,0) stable when no stimulus (2) Want Caf close to 1 when stimulus on At fixed C=10 Want S>C, Caf decreases with increasing S For C=S Choose S=C=200
23 Connect to Hill Model force Control strength of activation force-length force-velocity
24 Spike-Activation Models Modify k1(sr release rate) to model spike-activated release of Calcium from SR square-wave square-pulse a - height nu - frequency a - height tau - time on nu - frequency spike-pulse b - jump nu - Spike-time frequency tau_d - decay time constant
25 Spike-activated Model Simulation 5Hz spike-pulse 50Hz spike-pulse
26 Maximum Force vs. Frequency Biologically, expect force to increase with frequency Frequency
27 Summary - Important to develop integrated models for the neuromuscular junction We adapted a model to study spike-activation Found biologically realistic force vs. frequency relationship for some models Future Directions: - Match to experimental data (invertebrates) - Spike-time input into model, match force as function of time - Couple to stick-leg model of locomotion
28 Acknowledgements The authors would like to thank the organizers of the SAMSI Program on Computational Neuroscience. A special thank you also goes to Thomas Witelski for his help planning our workshop as well as the entire program.
29 Length-Tension Model FI - maximum isometric tension at a given length FIO - maximum isometric force produced at the optimum length of the muscle fibers LF - length of the muscle fibers LFO - length at which the muscle fibers exert their maximum tension SK is a constant specific for each muscle where SK > 0.28.
Session 3-Part 2: Skeletal Muscle
Session 3-Part 2: Skeletal Muscle Course: Introduction to Exercise Science-Level 2 (Exercise Physiology) Presentation Created by Ken Baldwin, M.ED, ACSM-H/FI Copyright EFS Inc. All Rights Reserved. Skeletal
More informationChapter 9 Muscle. Types of muscle Skeletal muscle Cardiac muscle Smooth muscle. Striated muscle
Chapter 9 Muscle Types of muscle Skeletal muscle Cardiac muscle Smooth muscle Striated muscle Chapter 9 Muscle (cont.) The sliding filament mechanism, in which myosin filaments bind to and move actin
More informationSkeletal Muscle. Connective tissue: Binding, support and insulation. Blood vessels
Chapter 12 Muscle Physiology Outline o Skeletal Muscle Structure o The mechanism of Force Generation in Muscle o The mechanics of Skeletal Muscle Contraction o Skeletal Muscle Metabolism o Control of Skeletal
More informationSkeletal Muscle Qiang XIA (
Skeletal Muscle Qiang XIA ( 夏强 ), PhD Department of Physiology Rm C518, Block C, Research Building, School of Medicine Tel: 88208252 Email: xiaqiang@zju.edu.cn Course website: http://10.71.121.151/physiology
More informationMUSCLE TISSUE (MUSCLE PHYSIOLOGY) PART I: MUSCLE STRUCTURE
PART I: MUSCLE STRUCTURE Muscle Tissue A primary tissue type, divided into: skeletal muscle cardiac muscle smooth muscle Functions of Skeletal Muscles Produce skeletal movement Maintain body position Support
More informationCh 12: Muscles sarcolemma, t-tubules, sarcoplasmic reticulum, myofibrils, myofilaments, sarcomere...
Ch 12: Muscles Review micro-anatomy of muscle tissue Terminology examples: sarcolemma, t-tubules, sarcoplasmic reticulum, myofibrils, myofilaments, sarcomere... SLOs Differentiate levels of muscle structure:
More informationOrganismic Biology Bio 207. Lecture 6. Muscle and movement; sliding filaments; E-C coupling; length-tension relationships; biomechanics. Prof.
Organismic Biology Bio 207 Lecture 6 Muscle and movement; sliding filaments; E-C coupling; length-tension relationships; biomechanics Prof. Simchon Today s Agenda Skeletal muscle Neuro Muscular Junction
More informationChapter 8: Skeletal Muscle: Structure and Function
Chapter 8: Skeletal Muscle: Structure and Function Objectives Draw & label the microstructure of skeletal muscle Outline the steps leading to muscle shortening Define the concentric and isometric Discuss:
More informationTable of Contents # Date Title Page # /27/14 Ch 7: Skeletal System 01/29/14 Ch 8: Muscular System
Table of Contents # Date Title Page # 1. 1 2. 3. 4. 5. 01/27/14 Ch 7: Skeletal System 01/29/14 Ch 8: Muscular System 12 i 1 01/30/14 Ch 8: Muscular System 12 Objective: Students will be able to describe
More informationThe organization of skeletal muscles. Excitation contraction coupling. Whole Skeletal Muscles contractions. Muscle Energetics
Muscle and Movement The organization of skeletal muscles Excitation contraction coupling Whole Skeletal Muscles contractions Muscle Energetics The molecular bases of movement Muscular cells use molecular
More informationBiomechanics of Skeletal Muscle
Biomechanics of Skeletal Muscle Contents I. Composition & structure of skeletal muscle II. Mechanics of Muscle Contraction III. Force production in muscle IV. Muscle remodeling V. Summary 2 Muscle types:
More informationMuscle Tissue- 3 Types
AN INTRODUCTION TO MUSCLE TISSUE Muscle Tissue- 3 Types Skeletal muscle (focus on these) Cardiac muscle Smooth muscle FUNCTIONS OF SKELETAL MUSCLES Produce movement of the skeleton Maintain posture and
More informationMuscle Cells & Muscle Fiber Contractions. Packet #8
Muscle Cells & Muscle Fiber Contractions Packet #8 Skeletal muscle is attached to bones and is responsible for movement. Introduction Introduction II Skeletal muscle is composed of bundles of muscle fibers
More informationCHAPTER 6 2/9/2016. Learning Objectives List the four traits that all muscle types have in common.
Learning Objectives List the four traits that all muscle types have in common. CHAPTER 6 The Muscular System Demonstrate and explain the use of antagonistic muscle pairs. Describe the attachment of muscle
More informationPSK4U THE NEUROMUSCULAR SYSTEM
PSK4U THE NEUROMUSCULAR SYSTEM REVIEW Review of muscle so we can see how the neuromuscular system works This is not on today's note Skeletal Muscle Cell: Cellular System A) Excitation System Electrical
More information10 - Muscular Contraction. Taft College Human Physiology
10 - Muscular Contraction Taft College Human Physiology Muscular Contraction Sliding filament theory (Hanson and Huxley, 1954) These 2 investigators proposed that skeletal muscle shortens during contraction
More informationNotebook Anatomy and Physiology CH 8 Muscle Structure.notebook January 08, 2015
Table of Contents # Date Title Page # 1. 08/27/14 Ch 1: Intro to Human A & P 1 2. 09/05/14 Ch 4: Cellular Metabolism 6 3. 09/09/14 Ch 5: Tissues 8 4. 09/29/14 Ch 12: Blood 25 5. 10/06/14 Ch 13: Cardiovascular
More informationChapter 9 - Muscle and Muscle Tissue
Chapter 9 - Muscle and Muscle Tissue I. Overview of muscle tissue A. Three muscle types in the body: B. Special characteristics 1. Excitability: able to receive and respond to a stimulus 2. Contractility:
More informationExcitation-Contraction Coupling & Reflexes, Proprioception and Movement. PSK 4U Unit 4, Day 4
Excitation-Contraction Coupling & Reflexes, Proprioception and Movement PSK 4U Unit 4, Day 4 Excitation-Contraction Coupling Muscles work by converting electrical and chemical energy into mechanical energy!
More informationMuscles and Animal Movement
Muscles and Animal Movement Evolution of Muscle and Movement Animals are the only multicellular organisms that actively move. Movement is due to muscle cells (motor proteins) Muscle proteins have homologues
More informationAnatomy & Physiology Muscular System Worksheet
Anatomy & Physiology Muscular System Worksheet 1. What are the three categories of muscle tissue? a) b) c) 2. The smallest functional unit of a muscle fiber is called a. 3. What are the four characteristics
More information1/4/2017. Introduction. Connective Tissue Coverings. 9.1: Structure of a Skeletal Muscle. Skeletal Muscle Fibers. Connective Tissue Coverings
Introduction Chapter 09 Lecture Outline See separate PowerPoint slides for all figures and tables preinserted into PowerPoint without notes. Copyright McGraw-Hill Education. Permission required for reproduction
More informationOutline. Bio 105: Muscular System. Muscular System. Types of Muscles. Smooth Muscle. Cardiac Muscle 4/6/2016
Outline Bio 105: Muscular System Lecture 11 Chapter 6 Characteristics of muscles 3 types of muscles Functions of muscles Structure of skeletal muscles Mechanics of muscle contraction Energy sources for
More informationCh 12 can be done in one lecture
Ch 12 can be done in one lecture Developed by John Gallagher, MS, DVM Chapter 12: Muscles Review muscle anatomy (esp. microanatomy of skeletal muscle) Terminology: sarcolemma t-tubules sarcoplasmic reticulum
More informationChapter 10! Chapter 10, Part 2 Muscle. Muscle Tissue - Part 2! Pages !
! Chapter 10, Part 2 Muscle Chapter 10! Muscle Tissue - Part 2! Pages 308-324! SECTION 10-5! Sarcomere shortening and muscle fiber stimulation produce tension! 2! Tension Production - Muscle FIBER! All-or-none
More information5. What component of the sarcomere is not attached to the Z line?
Model 2: Anatomy of a Sarcomere 1. Label the thick filament and the thin filament in Model 2. 2. How many sarcomeres are shown in Model 2? 3. Using Model 2, based on the locations of thick and thin filaments,
More informationNerve Muscle Relationship and Neural Muscular Junction Quiz. Remember, you need to know the structure and the function!
Nerve Muscle Relationship and Neural Muscular Junction Quiz Remember, you need to know the structure and the function! What is this called? What is this? Schwann cell What is this called? Basal lamina
More informationMuscle Physiology. Introduction. Four Characteristics of Muscle tissue. Skeletal Muscle
Muscle Physiology Introduction Muscle = tissue capable of forceful shortening or contraction Converts chemical energy (ATP) into mechanical energy Important in: Respiration Urine collection & flow Gastrointestinal
More informationNerve Cell (aka neuron)
Nerve Cell (aka neuron) Neuromuscular Junction Nerve cell Muscle fiber (cell) The Nerve Stimulus and Action Potential The Nerve Stimulus and Action Potential Skeletal muscles must be stimulated by a motor
More informationBIOLOGY - CLUTCH CH.49 - MUSCLE SYSTEMS.
!! www.clutchprep.com BIOLOGY - CLUTCH Muscle system organ system that includes skeletal, cardiac, and smooth muscle Muscle tissue capable of contracting through the interaction of actin and myosin proteins
More information3 muscle function_scr.notebook April 20, 2015
the key to muscle function is an excitable membrane sarcolemma proteins on the sarcolemma allow muscle cells to communicate with other cells and the environment specific to muscle function is communication
More informationMuscle Dr. Ted Milner (KIN 416)
Muscle Dr. Ted Milner (KIN 416) Muscles are biological motors which actively generate force and produce movement through the process of contraction. The molecular mechanism responsible for muscle contraction
More informationChapter 10 Muscle Tissue Lecture Outline
Chapter 10 Muscle Tissue Lecture Outline Muscle tissue types 1. Skeletal muscle = voluntary striated 2. Cardiac muscle = involuntary striated 3. Smooth muscle = involuntary nonstriated Characteristics
More informationMUSCULAR TISSUE. Dr. Gary Mumaugh
MUSCULAR TISSUE Dr. Gary Mumaugh MUSCLE OVERVIEW The three types of muscle tissue are skeletal, cardiac, and smooth These types differ in structure, location, function, and means of activation FUNCTIONAL
More informationSKELETAL MUSCLE CHARACTERISTICS
THE MUSCULAR SYSTEM SKELETAL MUSCLE CHARACTERISTICS Most are attached by tendons to bones Cells are multinucleate Striated have visible banding Voluntary subject to conscious control Cells are surrounded
More informationMuscle Physiology. Bio 219 Dr. Adam Ross Napa Valley College
Muscle Physiology Bio 219 Dr. Adam Ross Napa Valley College Muscle tissue Muscle is an excitable tissue capable of force production Three types Skeletal- striated, voluntary Cardiac- non-striated, involuntary
More informationConcept 50.5: The physical interaction of protein filaments is required for muscle function
Concept 50.5: The physical interaction of protein filaments is required for muscle function Muscle activity is a response to input from the nervous system The action of a muscle is always to contract Vertebrate
More informationSkeletal Muscle and the Molecular Basis of Contraction. Lanny Shulman, O.D., Ph.D. University of Houston College of Optometry
Skeletal Muscle and the Molecular Basis of Contraction Lanny Shulman, O.D., Ph.D. University of Houston College of Optometry Like neurons, all muscle cells can be excited chemically, electrically, and
More informationThe Nervous and Muscular Systems and the role of ATP
The Nervous and Muscular Systems and the role of ATP Overview of the Nervous System General parts: The brain The spinal cord The nerves and sense organs General functions: controls and coordinates body
More informationThe Muscular System PART A
6 The Muscular System PART A PowerPoint Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB The Muscular System
More informationHASPI Medical Anatomy & Physiology 09b Lab Activity
HASPI Medical Anatomy & Physiology 09b Lab Activity Name(s): Period: Date: Muscle Cell Structure Muscle cells are specialized to contract. An individual muscle is actually a bundle of hundreds to thousands
More informationMuscular System- Part 1. Unit 5 Miss Wheeler
Muscular System- Part 1 Unit 5 Miss Wheeler Fun Facts! The tongue is the strongest muscle in your body The smallest muscles in the body are in the middle ear The largest muscle in the body is the gluteus
More informationThe All-or-None Principle Motor units also comply to a rule known as the all-ornone principle (or law).
The All-or-None Principle Motor units also comply to a rule known as the all-ornone principle (or law). This principle stipulates that, when a motor unit is stimulated to contract, it will do so to its
More informationAbout This Chapter. Skeletal muscle Mechanics of body movement Smooth muscle Cardiac muscle Pearson Education, Inc.
About This Chapter Skeletal muscle Mechanics of body movement Smooth muscle Cardiac muscle Skeletal Muscle Usually attached to bones by tendons Origin: closest to the trunk or to more stationary bone Insertion:
More informationCh.10 Muscle Tissue. Copyright 2009, John Wiley & Sons, Inc.
Ch.10 Muscle Tissue Preview Chapter 10 In groups we will define the following terms 1. Skeletal muscle 2. Smooth muscle 3. Cardiac muscle 4. Sarcomere 5. Myofibril 6. Myofilament 7. Sarcoplasmic reticulum
More informationANSC (FSTC) 607 Physiology and Biochemistry of Muscle as a Food MUSCLE CONTRACTION
I. Basic model of muscle contraction A. Overall ANSC (FSTC) 607 Physiology and Biochemistry of Muscle as a Food MUSCLE CONTRACTION 1. Calcium is released from sarcoplasmic reticulum. 2. Myosin globular
More informationMicroanatomy of Muscles. Anatomy & Physiology Class
Microanatomy of Muscles Anatomy & Physiology Class Three Main Muscle Types Objectives: By the end of this presentation you will have the information to: 1. 2. 3. 4. 5. 6. Describe the 3 main types of muscles.
More informationChapter 10! Muscle Tissue - Part 2! Pages ! SECTION 10-5! Sarcomere shortening and muscle fiber stimulation produce tension!
! Chapter 10, Part 2 Muscle Chapter 10! Muscle Tissue - Part 2! Pages 308-324! SECTION 10-5! Sarcomere shortening and muscle fiber stimulation produce tension! 2! 1 Tension Production - MUSCLE FIBER! All-or-none
More informationCLASS SET Unit 4: The Muscular System STUDY GUIDE
NPHS Anatomy & Physiology Questions to answer: 1) List three functions of the muscular system. 1) movement 2) thermogenesis (generates heat) 3) posture & body/joint support CLASS SET Unit 4: The Muscular
More informationMusculoskeletal System. Terms. Origin (Proximal Attachment) Insertion (Distal Attachment)
Musculoskeletal System Terms Origin (Proximal Attachment) Insertion (Distal Attachment) Agonist- prime mover Antagonist- provides a braking force Synergist- assists indirectly in the movement Musculoskeletal
More informationMuscle Tissue. Muscle Tissue Outline. General Function of Muscle Tissue
Muscle Tissue Muscle Tissue Outline General Functions of Muscle Tissue Characteristics of Muscle Tissue Classification of Muscle Tissue Skeletal Muscle Structure and Function Muscle Energetics Muscle Mechanics
More information1. Locomotion. 2. Repositioning. 3. Internal movement
MUSCLE and MOVEMENT Chapters 20, 8, 21 1. Locomotion A. Movement B. 2. Repositioning A. 3. Internal movement A. 1 Muscle Cells 1. Contractile 2. Myocytes 3. Striated A. Skeletal B. Cardiac 4. Smooth 5.
More information1. Locomotion. 2. Repositioning. 3. Internal movement
MUSCLE and MOVEMENT Chapters 20, 8, 21 1. Locomotion A. Movement B. 2. Repositioning A. 3. Internal movement A. Muscle Cells 1. Contractile 2. Myocytes 3. Striated A. Skeletal B. Cardiac 4. Smooth 5. Striated
More informationChapter 50. You re on your own for: Sensory Reception Mechanoreceptors Gravity, Hearing and Equilibrium. Chemoreception taste and smell
1 Sensory and Motor Mechanisms 2 Chapter 50 You re on your own for: Sensory Reception Mechanoreceptors Gravity, Hearing and Equilibrium Chemoreception taste and smell Photoreceptors vision It s interesting.
More informationMuscle and Muscle Tissue
Muscle and Muscle Tissue Make up about half of total body mass Exerts force by converting chemical energy, ATP, to mechanical energy Muscle tissue is classified based on Shape Number and position of nuclei
More information(c) sarcolemma with acethylcholine (protein) receptors
(slide 1) Lecture Notes: Muscular System I. (slide 2) Introduction to Muscular System A) Tissues of the Muscular System: 1) Connective Tissues (a) dense fibrous (tendons and ligaments) 2) Nervous Tissue
More informationAnatomy and Physiology 1 Chapter 10 self quiz Pro, Dima Darwish,MD.
Anatomy and Physiology 1 Chapter 10 self quiz Pro, Dima Darwish,MD. 1) Which of the following is a recognized function of skeletal muscle? A) produce movement B) maintain posture C) maintain body temperature
More informationMuscle Function: Understanding the Unique Characteristics of Muscle. Three types of muscle. Muscle Structure. Cardiac muscle.
: Understanding the Unique Characteristics of Muscle Scott Riewald United States Olympic Committee Three types of muscle Cardiac muscle Involuntary Smooth muscle Involuntary Skeletal muscle Voluntary Involuntary
More informationLab #9: Muscle Physiology
Background Overview of Skeletal Muscle Contraction Sarcomere Thick Filaments Skeletal muscle fibers are very large, elongated cells (Fig 9.1). Roughly 80% of the content of each muscle fiber consists of
More informationIII. The Mechanism of Muscle Contraction (Pages 2-13) A. Excitation and Contraction - Crossbridge Cycling (Pages 2-8)
Content Display Unit 3 - Skeletal Muscle : Lesson 2 KINE xxxx Exercise Physiology 4 Unit 3 - Skeletal Muscle 3 Lesson 2 1 U3L2P1 - Introduction to Unit 3 - Lesson 2 Lesson 2 addresses the basic mechanism
More informationMuscles & Physiology
Collin County Community College BIOL 2401 Muscles & Physiology 1 Tension Development The force exerted by a contracting muscle cell or muscle group on an object is called muscle tension, and the opposing
More informationPage 1. Chapter 9: Muscle Tissue. Types of Muscle Tissue: Skeletal Muscle Cardiac Muscle Smooth Muscle. Characteristics of Muscle:
1 Chapter 9: Muscle Tissue Muscle little mouse Types of Muscle Tissue: Skeletal Muscle Cardiac Muscle Smooth Muscle Characteristics: Attaches to skeleton Voluntary control Striated / multi-nucleated Characteristics:
More informationHuman Anatomy & Physiology I with Dr. Hubley
Human Anatomy & Physiology I with Dr. Hubley Sample Final Exam Name: Instructions This exam consists of 50 questions. You may write on the exam itself, but be sure to answer all your questions on a Scantron
More informationThe Muscular System and Homeostasis
Chapter 10 Chapter 10 The Muscular System and Homeostasis The Muscular System and Homeostasis 10.1 Movement and Muscle Tissue 10.2 Muscles, Health, and Homeostasis 10.1 Movement and Muscle Tissue Muscles
More informationEQA DISCUSSION QUESTIONS: INFLUENCE OF MUSCLE FIBER TYPE ON MUSCLE CONTRACTION. Influence of Muscle Fiber Type on Muscle Contraction
0907T_c13_205-218.qxd 1/25/05 11:05 Page 209 EXERCISE 13 CONTRACTION OF SKELETAL MUSCLE 209 Aerobic cellular respiration produces ATP slowly, but can produce large amounts of ATP over time if there is
More informationAnimal Skeletons. Earthworm peristaltic movement. Hydrostatic Skeletons
Animal Skeletons The Musculo-Skeletal System Functions: Support Protection Movement all movement results from: muscle working against a skeleton 3 Types of skeletons hydrostatic exoskeleton endoskeleton
More informationChapter 10: Muscle Tissue
Chapter 10: Muscle Tissue Muscle is one of the 4 primary types of tissue. It is subdivided into skeletal, cardiac and smooth muscle. I. Skeletal Muscle Tissue and the Muscular System, p. 284 Objective
More informationBiology 2100 Human Physiology C. Iltis SLCC March 8, Midterm Examination #2
Biology 2100 Human Physiology Name: KEY C. Iltis SLCC March 8, 2000 Midterm Examination #2 Multiple Choice Questions (2 POINTS EACH) 1. When glucose levels are above 100 mg/dl, which of the following is
More informationChapter 8 Notes. Muscles
Chapter 8 Notes Muscles 8.1 Intro Three muscle types Skeletal Smooth cardiac 8.2 Structure of Skeletal Muscle Composition Skeletal muscle tissue Nervous tissue Blood Connective tissue Connective tissue
More informationMuscle Physiology. Dr. Ebneshahidi Ebneshahidi
Muscle Physiology Dr. Ebneshahidi Skeletal Muscle Figure 9.2 (a) Functions of the muscular system 1. Locomotion body movements are due to skeletal muscle contraction. 2. Vasoconstriction and vasodilatation
More informationA and P CH 8 Lecture Notes.notebook. February 10, Table of Contents # Date Title Page # /30/17 Ch 8: Muscular System
Table of Contents # Date Title Page # 1. 01/30/17 Ch 8: Muscular System 2. 1 3. 4. 5. 6. 7. i 1 Turnitin.com Class #: 13551662 Password: GoViks 2 01/30/17 Ch 8: Muscular System Objective: Students will
More informationAP Biology
Chapter 49. Animal Locomotion What are the advantages of locomotion? sessile motile Muscles & Motor Locomotion Muscle voluntary, striated involuntary, striated auto-rhythmic involuntary, non-striated 1
More informationChapter 49. Muscles & Motor Locomotion. AP Biology
Chapter 49. Muscles & Motor Locomotion Animal Locomotion What are the advantages of locomotion? sessile motile Muscle voluntary, striated involuntary, striated auto-rhythmic involuntary, non-striated
More informationName: Teacher: Olsen Hour:
Name: Teacher: Olsen Hour: Dem Bones Textbook p84-85, 88-99 61 In all exercises, quizzes and tests in this class, always answer in your own words. That is the only way that you can show that you understand
More informationChoroid Retina Fovea. Sclera. Suspensory ligament Cornea Iris. Optic nerve. Pupil. Aqueous humor Lens. Central artery and vein of the retina
Figure 50.1 Figure 50.17aa Sclera Suspensory ligament Cornea Iris Pupil Choroid Retina Fovea Optic nerve Aqueous humor Lens Vitreous humor Optic disk Central artery and vein of the retina Figure 50.26
More informationMuscles and Muscle Tissue
1 Muscles and Muscle Tissue Chapter 9 2 Overview of Muscle Tissues Compare and Contrast the three basic types of muscle tissue List four important functions of muscle tissue 3 Muscle Terminology Muscle
More informationMUSCULAR SYSTEM CHAPTER 09 BIO 211: ANATOMY & PHYSIOLOGY I
1 BIO 211: ANATOMY & PHYSIOLOGY I 1 CHAPTER 09 MUSCULAR SYSTEM Part 2 of 2 Dr. Dr. Lawrence G. G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill. Some illustrations are courtesy
More information1. Differences in function of the 3 muscle types: a) Skeletal Muscle b) Cardiac Muscle c) Smooth Muscle
Ch 9: Muscle Physiology Objectives: 1. Review 3 muscle types and how they are regulated. 2. Review muscle anatomy. 3. Sliding filament theory of how muscles contract and relax. 4. Energetics of muscle
More informationPage 1. Chapter 9: Muscle Tissue. Types of Muscle Tissue: Skeletal Muscle Cardiac Muscle Smooth Muscle. Gross Anatomy of Muscle:
1 Chapter 9: Muscle Tissue Types of Muscle Tissue: Skeletal Muscle Cardiac Muscle Smooth Muscle Characteristics: Attaches to skeleton Voluntary control Striated / multi-nucleated Characteristics: Composes
More informationSmooth Cardiac Skeletal Location Around tubes Heart tissue attached to skeleton Moves stuff thru Heart beat pumps Moves body parts
Biology 067 - Muscular system A. Type of muscles: Smooth Cardiac Skeletal Location Around tubes Heart tissue attached to skeleton Function Moves stuff thru Heart beat pumps Moves body parts tubes blood
More informationMuscle Tissue. PowerPoint Lecture Presentations prepared by Jason LaPres. Lone Star College North Harris Pearson Education, Inc.
10 Muscle Tissue PowerPoint Lecture Presentations prepared by Jason LaPres Lone Star College North Harris An Introduction to Muscle Tissue Muscle Tissue A primary tissue type, divided into: Skeletal muscle
More informationFig Copyright McGraw-Hill Education. Permission required for reproduction or display. Nucleus. Muscle fiber. Endomysium. Striations.
Fig. 11.1 Nucleus Muscle fiber Endomysium Striations Ed Reschke 1 Fig. 11.2 Muscle fiber Nucleus I band A band Z disc Mitochondria Openings into transverse tubules Sarcoplasmic reticulum Triad: Terminal
More informationStructural Support and Movement. Chapter 36
Structural Support and Movement Chapter 36 Impacts, Issues Pumping Up Muscles Increasing muscle size and strength with drugs such as andro has unwanted side effects and can damage other organ systems 36.1
More informationBCH 450 Biochemistry of Specialized Tissues. V. Muscle Tissues
BCH 450 Biochemistry of Specialized Tissues V. Muscle Tissues Nomenclature Sarcolemma = plasma membrane Sarcoplasmic reticulum = endoplasmic reticulum Muscle fiber = cell Myofibril = subcellular fibers
More informationThe Musculoskeletal System. Chapter 46
The Musculoskeletal System Chapter 46 Types of Skeletal Systems Changes in movement occur because muscles pull against a support structure Zoologists recognize three types: 1. Hydrostatic skeletons a fluid
More informationClass XI Chapter 20 Locomotion and Movement Biology
Question 1: Draw the diagram of a sarcomere of skeletal muscle showing different regions. The diagrammatic representation of a sarcomere is as follows: Question 2: Define sliding filament theory of muscle
More informationPrinciples of Anatomy and Physiology
Principles of Anatomy and Physiology 14 th Edition CHAPTER 10 Muscular Tissue Introduction The purpose of the chapter is to: 1. Learn about the structure and function of the 3 types of muscular tissue
More informationChapter 7 The Muscular System. Mosby items and derived items 2012 by Mosby, Inc., an affiliate of Elsevier Inc. 1
Chapter 7 The Muscular System Mosby items and derived items 2012 by Mosby, Inc., an affiliate of Elsevier Inc. 1 INTRODUCTION A. Muscular tissue enables the body and its parts to move 1. Three types of
More informationMuscle Cell Anatomy & Function (mainly striated muscle tissue)
Muscle Cell Anatomy & Function (mainly striated muscle tissue) General Structure of Muscle Cells (skeletal) several nuclei (skeletal muscle) skeletal muscles are formed when embryonic cells fuse together
More informationMuscular System. Honors Anatomy & Physiology. Susan Chabot Lemon Bay High School
Muscular System Honors Anatomy & Physiology Susan Chabot Lemon Bay High School Skeletal, Smooth, or Cardiac SKELETAL Striated Voluntary Multinucleated Bound to bones Moves skeleton SMOOTH Not striated
More informationMuscular Tissue. Functions of Muscular Tissue. Types of Muscular Tissue. Skeletal Muscular Tissue. Properties of Muscular Tissue
Muscular Tissue Functions of Muscular Tissue Muscle makes up a large percentage of the body s weight (40-50%) Their main functions are to: Create motion muscles work with nerves, bones, and joints to produce
More informationChapter 50: Sensory and Motor Mechanisms
Name Period As in Chapter 49, there are several topics in this chapter that we will emphasize only lightly. If your teacher stresses human anatomy and physiology, you may be expected to go into more depth.
More informationBiomechanics. MCE 493/593 & ECE 492/592 Prosthesis Design and Control September
Biomechanics MCE 493/593 & ECE 492/592 Prosthesis Design and Control September 9. 2014 Antonie J. (Ton) van den Bogert Mechanical Engineering Cleveland State University 1 Viewpoint Scientific background
More informationLecture 13, 09 Oct 2003 Chapter 10 Muscles. Vertebrate Physiology ECOL 437 University of Arizona Fall instr: Kevin Bonine t.a.
Lecture 13, 09 Oct 2003 Chapter 10 Muscles Vertebrate Physiology ECOL 437 University of Arizona Fall 2003 instr: Kevin Bonine t.a.: Bret Pasch Vertebrate Physiology 437 1. Muscles (Ch10) 2. Announcements
More informationChapter 10 -Muscle Tissue
Chapter 10 -Muscle Tissue Muscles: 1. Overview of Muscle Tissue A. Review 5 functions of muscle tissue. B. Review the 5 properties of muscle tissue. WHICH do they share with nervous tissue? (2, plus the
More informationSkeletal Muscle. Skeletal Muscle
Skeletal Muscle Skeletal Muscle Types of muscle Skeletal muscle-moves the skeleton by pulling on the tendons that are connected to the bones Cardiac muscle-pumps blood through the heart and blood vessels
More information-Detect heat or cold and help maintain body temperature
Sensory Receptors -Transduce stimulus energy and transmit signals to the central nervous system -Reception occurs when a receptor detectd a stimulus -Perception occurs in the brain as this information
More informationHuman Anatomy and Physiology - Problem Drill 09: The Muscular System
Human Anatomy and Physiology - Problem Drill 09: The Muscular System Question No. 1 of 10 The muscular system of the human body fulfills many different roles. Which of the following statements about the
More informationHole s Human Anatomy and Physiology Eleventh Edition. Mrs. Hummer. Chapter 9 Muscular System
Hole s Human Anatomy and Physiology Eleventh Edition Mrs. Hummer Chapter 9 Muscular System 1 Chapter 9 Muscular System Skeletal Muscle usually attached to bones under conscious control striated Three Types
More informationSkeletal Muscle Contraction and ATP Demand
Skeletal Muscle Contraction and ATP Demand Anatomy & Structure Contraction Cycling Calcium Regulation Types of Contractions Force, Power, and Contraction Velocity Epimysium - separates fascia and muscle
More information