Certification in Congenital Heart Disease Echocardiography. Syllabus

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1 Certification in Congenital Heart Disease Echocardiography Syllabus European Association of CardioVascular Imaging (EACVI)) Association for European Paediatric Cardiology (AEPC) Working Group on Grown-up Congenital Heart Disease of ESC (WG 22) Introduction: This syllabus is a guide for candidates wishing to pursue certification in congenital heart echocardiography. The candidate is expected to know and be skilled in basic principles of cardiac ultrasound. Additionally, they should know and understand the range of congenital heart defects in children and adults, and acquired heart defects in childhood. Although not all candidates will have the opportunity to train or work in cardiac surgical centres, they should be competent in the echocardiographic evaluation of unoperated congenital heart disease, the assessment of patients for surgical or catheter treatment, and post-procedural review. Intraoperative and cardiac catheter guidance for interventions is more advanced and the candidate is not expected to have experience of this, although an understanding of this is encouraged. 1

2 Part I. General Concepts... 4 The clinical role of echocardiography and Doppler in paediatric and congenital heart disease... 4 Service provision... 4 Relationship with patients... 4 Conscious sedation in children... 4 Reporting and documentation of paediatric and congenital studies... 4 Safety of ultrasound... 4 Part II. Imaging physics & instrumentation in paediatric and congenital echocardiography.. 5 Concepts and terminology of cardiac ultrasound... 5 Propagation of ultrasound through tissues... 5 Ultrasound Transducers... 5 Imaging physics... 5 Echo Instrumentation... 5 Optimising Images... 6 Part III. Doppler physics & fluid dynamics in paediatric and congenital... 6 echocardiography... 6 Basic Fluid Dynamics... 6 Basic Principles of Doppler... 6 Spectral Doppler... 6 Colour Flow Instrumentation... 7 Measurements and calculations... 7 Tissue Doppler Imaging (TDI) and Deformation... 7 Part IV. Cardiac anatomy and physiology for paediatric and adult congenital echocardiography anatomy of the thorax... 8 General thoracic anatomy... 8 General concepts of cardiac morphology and echo identification... 8 Terminology of congenital heart disease... 9 The cardiac cycle... 9 Fetal and neonatal physiology... 9 The physiology of congenital heart disease... 9 Part V. The different congenital heart defects and treatment for the paediatric and congenital echocardiographer A) Septation defects Ventricular septal defect (VSD) Atrial septal defect (ASD) Atrioventricular septal defect (AVSD) B. Shunt lesions not caused by septation defects Arterial duct Partial anomalous pulmonary venous drainage (PAPVD) Basic anatomy and echocardiographic features of other acyanotic shunts C. Cyanotic congenital heart defects Ventriculoarterial discordance (transposition of the great arteries)

3 Tetralogy of Fallot (TOF)/pulmonary atresia with ventricular septal defect (PA/VSD) Pulmonary atresia with intact septum (PA/IVS) Total anomalous pulmonary venous drainage (TAPVD) D. Other complex lesions Common arterial trunk (CAT) Lesions with single ventricle physiology Atrioventricular and ventriculoarterial discordance (AV/VA discordance) Double outlet right ventricle (DORV) E. Congenital valve disease The mitral valve The aortic valve The pulmonary valve The tricuspid valve (including Ebstein s Malformation) Prosthetic Valves F. Left outflow obstruction Subvalvular/supravalvar aortic stenosis Coarctation of the aorta Interrupted aortic arch G. Right outflow obstruction Subvalvular/supravalvar stenosis/peripheral branch stenosis H. Congenital coronary anomalies Anomalous origin of the left coronary artery Coronary fistulae I. Miscellaneous lesions Cortriatriatum dexter and sinister Intracardiac Masses Diseases of the aorta Pericardial Disease Part VI. Acquired heart disease in paediatrics and congenital heart disease Kawasaki disease Infective Endocarditis Rheumatic fever Intravascular thrombosis Part VII. Cardiac functional evaluation in paediatric and adult congenital heart disease A. Ventricular Function Calculations Diastolic function B. Pulmonary hypertension Pulmonary Hypertension C. Conditions associated with ventricular dysfunction Dilated Cardiomyopathy Hypertrophic Cardiomyopathy Restrictive Cardiomyopathy

4 PART I. GENERAL CONCEPTS The clinical role of echocardiography and Doppler in paediatric and congenital heart disease Indications for echocardiography Information that echocardiography can and cannot provide Ruling out pathology (sensitivity, specificity & Baye s theorem) Likelihood of findings influencing patient management Role of multimodality imaging: o Cardiac catheterisation o Multislice CT scan o Magnetic resonance imaging o Nuclear Cardiology Service provision Advantages and disadvantages of physiologist-led versus physician-led service Specific requirements for paediatric and congenital echocardiography laboratories Provision and indication for specialised techniques, e.g. Transoesphageal echocardiography Availability and access Controlling workload Training & motivation of staff Audit, Quality Control, Clinical Governance Relationship with patients Explaining the procedure in terms relevant to the patient/parents Respect for patients dignity and cultural backgrounds Relationships with patient, parents and colleagues Handling requests for information about the study findings Conscious sedation in children Explaining the procedure in terms relevant to the patient/parents Specific environment for performing studies in children/adults with CHD Indications for conscious sedation Precautions, dosage, follow-up Reporting and documentation of paediatric and congenital studies Standard methods and terminology used for describing congenital heart disease (segmental sequential analysis) Distinction between technical and clinical reports Responsibility for reporting Medico-legal considerations (Data Protection Act) Safety of ultrasound Potential hazardous biological effects o Heating, resonance and cavitation effects Measurement of beam intensity (Spatial Peak Temporal Average, [SPTA]) Practical precautions: power levels, use of colour and continuous wave Doppler 4

5 PART II. IMAGING PHYSICS & INSTRUMENTATION IN PAEDIATRIC AND CONGENITAL ECHOCARDIOGRAPHY Concepts and terminology of cardiac ultrasound Concept of compression waves Definitions: frequency, wavelength, propagation velocity Units of measurement: Hz and MHz, Decibel Comparison of Ultrasound with audible sound Propagation of ultrasound through tissues Speed of sound in different body tissues Frequency range used for diagnostic imaging in children and adults with CHD Distinction between specular reflection and backscatter Principles of attenuation and scattering Ultrasound Transducers Piezo-electric effect General concepts of transducer construction Characteristics of the ultrasound beam: o Near (Fresnel) & Far (Fraunhofer) zones, side lobes Beam steering methods: mechanical & electronic Focusing methods, including multiple transmit focusing Imaging physics Factors affecting choice of imaging frequency: o Typical practical values for adults & children Measurement and optimisation of resolution: axial, azimuthal and elevation Broad-band imaging Harmonic imaging B mode and M Mode methods Scanning speed limitations, relationships between pulse repetition frequency, frame rate, lines per frame, field of view, depth to be imaged. Concept of Parallel Processing and its influence on frame rate and image quality Effect on evaluation of rapid motion, temporal resolution Grey scale and dynamic range Lateral resolution and grating artefacts Reverberation artefacts Limiting factors for detecting small targets Echo Instrumentation Function of machine controls: o Transmit power; overall gain; time gain compensation; reject, logarithmic compression Signal processing, dynamic range, pre-processing, post processing Optimisation of imaging parameters including: o Transducer frequency, scan angle, gamma correction, spatial and temporal smoothing 5

6 Optimising Images Use of gel Positioning of the subject Standard views: o Parasternal, apical (4, 5 and 2-chamber), subcostal, suprasternal, right parasternal, long and short axis Use of non-standard views Adapting for subjects with difficult windows PART III. DOPPLER PHYSICS & FLUID DYNAMICS IN PAEDIATRIC AND CONGENITAL ECHOCARDIOGRAPHY Basic Fluid Dynamics Fluid flow: significance of peak and mean velocities Determination of volumetric flow Continuity equation Laminar & turbulent flow: Reynolds equation (qualitative) Transition from Laminar to turbulent flow: inlet jet Bernoulli equation Basic Principles of Doppler Interaction of ultrasound waves with moving blood: the Doppler effect The Doppler equation: factors influencing magnitude of Doppler shift Spectral analysis: fast Fourier transform (qualitative) The spectral Doppler display: determination of mean, modal and peak velocities Limitation of CW Doppler caused by lack of depth discrimination The effect of beam angle errors on Doppler velocities Aliasing: o How it is caused and how it manifests in practice: the Nyquist limit o Influence on aliasing of: transducer frequency; sample depth (range x velocity product); and beam angle High pulse repetition frequency (extended range) PW Doppler Relative advantages and disadvantages of CW, PW and HPRF modes Concept of colour flow imaging as multi-sampled PW Velocity estimation, by moving target indication and autocorrelation (qualitative) Limitations of mean velocity: use of velocity variance to show high velocities/turbulence Aliasing in colour Doppler Packet size, colour mode and sector size and their effect on frame rate and aliasing Spectral Doppler Duplex Doppler using imaging transducers The stand-alone Doppler probe (pencil probe) Features of the spectral display: positive & negative velocities; scale & baseline controls. Effect of high- and low-pass filter and intensity threshold ( reject ) settings Pulsed Doppler sample volume: influence of gate length and distance (beam width) Representation of signal strength by image intensity How aliasing manifests on the spectral display 6

7 Colour Flow Instrumentation The colour display: Blue-Away, Red-Towards (BART) convention Colour maps to show velocity scales Image domination and additive colour modes Basic principles of Tissue Doppler Imaging, including optimisation of filters for detecting tissue versus blood velocities Difference between velocity and power (signal amplitude) displays Measurements and calculations On-screen measurement of length, slope, area, volume and time interval, and their significance for 2-D images, M-mode and spectral Doppler displays Standard M-mode measurements and calculations o Shortening Fraction o TAPSE o Wall thickness Limitations of measurements and/or calculations Peak and Mean pressure gradient measurements by Doppler and their relationship to catheterisation data Tissue Doppler Imaging (TDI) and Deformation Understand principles of TDI Identify a, e s on PW-TDI Limitations of measurements and/or calculations Understand age.size related differences in TDI measurements Understand concept of Displacement imaging Strain and strain rate Definition Direction of deformation Speckle Tracking Echocardiography Principles Physical origin of speckles Tracking of speckle motion Clinical applications Haemodynamic assessment -Assessment of filling pressures Systolic (global and regional) function / Diastolic function Detection of subclinical myocardial dysfunction 7

8 PART IV. CARDIAC ANATOMY AND PHYSIOLOGY FOR PAEDIATRIC AND ADULT CONGENITAL ECHOCARDIOGRAPHY ANATOMY OF THE THORAX General thoracic anatomy Thorax contained by rib cage & diaphragm Lungs & pleura Heart & pericardium Mediastinum Blood vessels within the thorax General concepts of cardiac morphology and echo identification Atrial situs: o Definition, abdominal aorta and great vein relationship Systemic venous return: morphology Pulmonary venous return: morphology Atrial anatomy: o Difference between right and left atrium, atrial appendages Ventricular anatomy: o Morphology of right and left ventricle o Atrioventricular valve arrangement o Trabecular pattern o Ventricular shape o Right-handed vs. left handed ventricular configuration o Inlet and outlet valve relationships o Chordal attachments Atrioventricular valves: anatomy of mitral and tricuspid valve Semilunar valves: anatomy of pulmonary and aortic valve The inter-atrial septum: o Morphology o Primum and secundum septum o Foramen ovale o Sinus venosus The interventricular septum: o Morphology o Inlet septum o Outlet septum o Membranous septum o Trabecular Pulmonary artery anatomy Aortic anatomy Coronary artery anatomy: normal anatomy and variants The arterial duct: normal anatomy and normal variants The pericardium: anatomy Visualisation of normal cardiac anatomy and normal variants in standard echocardiography planes Normal valve function, normal Doppler parameters and normal variants 8

9 Terminology of congenital heart disease Atrial situs and situs abnormalities: o Situs inversus o Right and left isomerism Atrioventricular connections: o Concordant o Discordant o Double inlet o Absent connection o Straddling valves o Criss-cross connections Univentricular heart: description of different variants Ventriculoarterial connections: o Concordant, o Discordant o Single outlet o Double outlet Great artery relationships The cardiac cycle Temporal relationships of the ECG, chamber pressures and valve movements Typical values for intracardiac pressures Relationship of valve movements to heart sounds Fetal and neonatal physiology The fetal circulation: how it differs from the postnatal circulation Circulatory changes at birth: the neonatal circulation Adaptations in circulatory physiology during the first weeks of life The physiology of congenital heart disease Causes of chamber dilation and hypertrophy Ventricular pressure and volume overload Physiological effect of shunts at atrial, ventricular and great artery level Physiological effect of regurgitation through all four valves Physiological effect of stenosis on all four valves 9

10 PART V. THE DIFFERENT CONGENITAL HEART DEFECTS AND TREATMENT FOR THE PAEDIATRIC AND CONGENITAL ECHOCARDIOGRAPHER A) Septation defects Ventricular septal defect (VSD) Assessment of unoperated VSD: o Location and size o M-mode and 2D features o Assessment of shunt size and pulmonary pressure o Anterior or posterior malalignment Associated features: o Aortic valve cusp prolapse o Discrete subvalvular aortic stenosis o Double chambered right ventricle Echocardiographic assessment of surgical treatment for VSD: o Post-operative complications: e.g. residual defects, sub-aortic stenosis Echocardiographic assessment of percutaneous treatment for different types of VSD. Atrial septal defect (ASD) Assessment of unoperated ASD: o Secundum, primum and sinus venosus defects o Location and size o M-mode and 2D echo features o Assessment of shunt size o Common associated lesions Other causes of right ventricular volume overload Echocardiographic assessment of surgical treatment of different types of ASD Echocardiographic assessment of percutaneous treatment of ASD. Atrioventricular septal defect (AVSD) Assessment of unoperated AVSD: o Size of atrial and ventricular components o Atrioventricular valve function o Ventricular imbalance o Assessment of pulmonary pressure Echocardiographic assessment of post-operative AVSD: o Atrioventricular valve function o Sub-aortic stenosis o Residual defects B. Shunt lesions not caused by septation defects Arterial duct Assessment of patent arterial duct o Imaging planes for isolated duct o Assessment of shunt size o Ductal flow patterns and pulmonary artery pressure 10

11 o Anatomical variations with different cardiac defects Other defects causing shunt at great artery level Echocardiographic assessment of surgical and percutaneous treatment for patent arterial duct Partial anomalous pulmonary venous drainage (PAPVD) Assessment of partial anomalous pulmonary venous drainage o Anatomy which veins drain where o Associated defects o Haemodynamic effect Echocardiographic assessment of surgical treatment for PAPVD Basic anatomy and echocardiographic features of other acyanotic shunts Aortopulmonary window Unroofed coronary sinus Origin of one pulmonary artery from aorta Sinus of Valsalva fistula C. Cyanotic congenital heart defects Ventriculoarterial discordance (transposition of the great arteries) Assessment of unrepaired ventriculoarterial discordance: o Anatomy o Coronary artery anatomy o Associated features: VSD, pulmonary stenosis, coarctation Echocardiographic assessment of surgical treatment for ventriculoarterial discordance o Atrial switch (Mustard, Senning) o Arterial switch o Rastelli procedure Tetralogy of Fallot (TOF)/pulmonary atresia with ventricular septal defect (PA/VSD) Assessment of unrepaired TOF/pulmonary atresia with VSD: o Anatomy o Assessment of VSD o Right ventricular outflow tract assessment o Coronary artery anatomy o Sources of pulmonary blood flow o Size of branch pulmonary arteries o Arch laterality Echocardiographic assessment of surgical treatment for TOF/pulmonary atresia with VSD: o Palliations: arterial shunt, right ventricular outflow tract stent, arterial ductal stent, pulmonary valve balloon o Valve sparingtransannular patch o Right ventricle to pulmonary artery conduit o Haemodynamic effect of residual stenosis or regurgitation Pulmonary atresia with intact septum (PA/IVS) Assessment of unrepaired PA/IVS o Anatomy 11

12 o Pulmonary valve morphology o Coronary artery anatomy/fistulae/sinusoids o Right ventricular morphology Echocardiographic assessment of percutaneous and surgical treatments for PA/IVS: o Arterial shunt, right ventricular outflow tract stent, arterial ductal stent, radiofrequency perforation and pulmonary valve balloon Total anomalous pulmonary venous drainage (TAPVD) Assessment of unrepaired TAPVD o Anatomy o Location: supracardiac, cardiac, infracardiac o Size of pulmonary veins o Associated features Echocardiographic assessment of surgical treatment for TAPVD: o Patency of confluence o Pulmonary vein stenosis o Right heart pressures D. Other complex lesions Common arterial trunk (CAT) Assessment of unrepaired CAT: o Anatomy o Morphology and function of truncal valve o Size and position of VSD o Committal of truncal valve to ventricle o Origin of pulmonary arteries o Coronary artery origins o Associated defects Echocardiographic assessment of surgical treatment for CAT: o Truncal valve stenosis/regurgitation o Pulmonary artery stenosis o Right ventricle to pulmonary artery conduit function Lesions with single ventricle physiology Different variants: double inlet ventricles, double outlet ventricles, hypoplastic/absent atrioventricular connections etc Anatomy: o Morphology of ventricle o Source of pulmonary blood flow o Source of systemic blood flow o Atrioventricular and ventriculoarterial valve function Echocardiographic evaluation after staged palliation for single ventricle physiology: o Pulmonary artery banding o Norwood procedure o Arterial shunt o Bidirectional Glenn/hemi-Fontan o Fontan/total cavopulmonary connection (TCPC) 12

13 Echocardiographic evaluation of the Fontan/(TCPC): o Types of Fontan/TCPC (atriopulmonary, lateral tunnel, extracardiac conduit) o Obstructions to the Fontan tunnel o Thromboses o Single ventricle function o Fenestration flow Atrioventricular and ventriculoarterial discordance (AV/VA discordance) Assessment of unrepaired AV/VA discordance: o Ventricular morphology o Associated defects Echocardiographic follow-up of the unoperated patient: o Function of the systemic right ventricle and tricuspid valve Echocardiographic follow-up of the operated patient: o Double switch (atrial and arterial switch) Double outlet right ventricle (DORV) Assessment of the unoperated patient with DORV: o Arrangement of the great vessels (and the relevant physiology) o Size and location of the VSD o Associated lesions Echocardiographic assessment of the surgical treatment of DORV: o Residual VSD o Left or right ventricular outflow tract obstruction E. Congenital valve disease The mitral valve Assessment of the congenitally abnormal mitral valve: o Anatomy and different variants of mitral valve anomalies o Nomenclature for mitral valve leaflets o Description of the valve o Description of subvalvar apparatus o Measurement of orifice area by planimetry o Assessment of severity of stenosis/regurgitation Doppler assessment of the mitral valve: o Mean and end-diastolic gradient o Area by pressure half-time : technique and limitations Mitral valve prolapse: definition and echocardiographic aspects Echocardiographic assessment of surgical mitral valve repair The aortic valve Assessment of the congenitally abnormal aortic valve: o Morphology of the aortic valve o Number of leaflets o Assessment of the left ventricle: size, hypertrophy, systolic and diastolic function o Associated left ventricular outflow tract abnormalities o Effect on the aortic root o Assessment of severity of stenosis/regurgitation 13

14 Doppler assessment of the aortic valve: o Peak and mean gradients o Apical, right parasternal and suprasternal positions o Continuity equation Echocardiographic assessment of surgical and percutaneous treatments for congenital aortic valve disease o Aortic valve balloon o Aortic valve repair o Aortic valve replacement o Ross procedure o Left ventricular remodelling The pulmonary valve Assessment of the congenitally abnormal pulmonary valve: o Morphology of the pulmonary valve o Number of leaflets o Assessment of the right ventricle: size, hypertrophy, systolic and diastolic function o Associated right ventricular outflow tract abnormalities o Assessment of severity of stenosis/regurgitation Echocardiographic assessment of surgical and percutaneous treatments for congenital pulmonary valve disease o Pulmonary valve balloon o Pulmonary valve repair o Pulmonary valve replacement o Right ventricular remodelling The tricuspid valve (including Ebstein s Malformation) Assessment of the congenitally abnormal tricuspid valve: o Morphology of the tricuspid valve o Position of tricuspid valve annulus o Number of leaflets o Assessment of the right ventricle and right atrium: size, function o Associated abnormalities o Assessment of stenosis/regurgitation Echocardiographic assessment of surgical and percutaneous treatments for congenital tricuspid valve disease o Tricuspid valve repair o Cone repair Prosthetic Valves 2D, M-Mode and Doppler features of the main types of replacement valves: o Ball & cage o Tilting Disc o Bi-leaflet o Stented Bioprostheses 14

15 Age-related deterioration of bioprostheses Understand role of TOE in examining normal and malfunctioning prosthetic valves Prosthetic valve stenosis o Assessment by 2D, M-mode and Doppler o Normal ranges o Use of Continuity Equation for aortic prostheses Prosthetic valve regurgitation o Trans-versus para-valvar regurgitation o Normal versus abnormal regurgitation Assessment by CW, PW and Colour Doppler Colour artefacts from mechanical prostheses F. Left outflow obstruction Subvalvular/supravalvar aortic stenosis Anatomy and variants Associated lesions Echocardiographic assessment of severity Evaluation of surgical treatment Coarctation of the aorta Type of narrowing Site of narrowing Morphology and anatomy of the whole arch Associated defects Echocardiographic assessment: o Different echocardiographic appearances o Spectral Doppler appearances o Peak velocity and diastolic pattern o Relationship to measured gradient o Relationship to severity of obstruction Effect of arterial duct on imaging and Doppler appearances Echocardiographic assessment of percutaneous and surgical treatment of coarctation of the aorta: o Recoarctation o Left ventricular remodelling Interrupted aortic arch Site of interruption Associated lesions Echocardiographic assessment of surgical treatment of interrupted aortic arch G. Right outflow obstruction Subvalvular/supravalvar stenosis/peripheral branch stenosis Anatomy and variants Associated lesions Echocardiographic assessment of severity Evaluation of surgical treatment 15

16 H. Congenital coronary anomalies Anomalous origin of the left coronary artery Origin of coronary arteries Physiological effect Assessment of surgical treatment for anomalous origin of the coronary artery Coronary fistulae Origin of coronary arteries and drainage of fistulae Physiological effect Assessment of surgical treatment and percutaneous treatment for coronary fistulae I. Miscellaneous lesions Cortriatriatum dexter and sinister Anatomy and echocardiographic appearance Intracardiac Masses Typical locations for intracardiac tumours Echocardiographic features intracardiac tumours Differentiation of cardiac tumours Features suggestive of malignancy Understand role of TOE in assessment of intracardiac masses Diseases of the aorta Technique for examining the ascending and descending thoracic aorta Echocardiographic features of the normal aortic root, sinuses of Valsalva, ascending aorta and aortic arch 2-D, M-mode and Doppler features of: o Marfan s syndrome o Sinus of Valsalva aneurysm Pericardial Disease Anatomy of the normal pericardium: o Relationships of serous pericardium to heart and great vessels o Transverse and oblique sinuses of the pericardium Echocardiographic features of pericardial fluid o Location of fluid in relation to patient position and fluid volume o Differentiation from pleural effusion o Assessment of volume of pericardial fluid o Role of echocardiography in pericardiocentesis Features of tamponade o Collapse of RA and/or RV walls o Effect on IVC o Effect on A-V valve flow velocities Features of pericardial constriction o Effect on A-V valve flow velocities o Effect of respiration 16

17 o SVC/hepatic vein flow o Differentiation from restrictive cardiomyopathy PART VI. ACQUIRED HEART DISEASE IN PAEDIATRICS AND CONGENITAL HEART DISEASE Kawasaki disease Common echocardiographic features Echocardiographic follow-up Infective Endocarditis Typical echocardiographic appearance of vegetations in bacterial and fungal endocarditis Preferred locations for vegetations o Jet lesions o Congenitally abnormal structures o Hypertrophic cardiomyopathy Complications: abscess, fistula, perforation Understand role of TOE in suspected endocarditis Echocardiographic follow-up Rheumatic fever Common echocardiographic features Evaluation of severity Echocardiographic follow-up Intravascular thrombosis Diagnostic echocardiographic criteria Echocardiographic follow-up PART VII. CARDIAC FUNCTIONAL EVALUATION IN PAEDIATRIC AND ADULT CONGENITAL HEART DISEASE A. Ventricular Function Calculations Derivation of Stroke Volume, Ejection Fraction and LV Mass Methods of measuring LV volume, including biplane area, area-length and Simpson s rule methods Echocardiographic calculation of cardiac output Diastolic function Methods of measuring diastolic dysfunction: E/A ratio, deceleration time, pulmonary venous flow patterns Tissue Doppler derived E/e 17

18 B. Pulmonary hypertension Pulmonary Hypertension 2-D, M-mode and Doppler features of pulmonary hypertension Causes of pulmonary hypertension: o Idiopathic o Related to congenital heart disease o Chronic pulmonary emboli o Secondary to lung diseases o Upper airway obstruction o Medication related Measurement of pulmonary pressures from tricuspid and pulmonary regurgitant flow velocities Assessment of inferior vena cava contraction C. Conditions associated with ventricular dysfunction Dilated Cardiomyopathy 2D, M-mode and Doppler features of dilated cardiomyopathy Detection and assessment of associated lesions: functional valve regurgitation Thrombus in cardiac chambers Pericardial effusions Associated abnormalities, e.g. mitral regurgitation Role of echocardiography in assessment and follow-up Hypertrophic Cardiomyopathy 2D, M-mode and Doppler features of hypertrophic cardiomyopathy Differentiation from other causes of hypertrophy, e.g. athletic heart Techniques for measurement of left ventricular wall thickness, detection of intracavity flow acceleration Assessment of right ventricular involvement Associated abnormalities, e.g. mitral regurgitation Role of echocardiography in assessment and follow-up Restrictive Cardiomyopathy 2D, M-mode and Doppler features of restrictive cardiomyopathy Differentiation from pericardial constriction Techniques for measurement of diastolic dysfunction Associated abnormalities, e.g. mitral regurgitation Role of echocardiography in assessment and follow-up 18

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