MODULE 15: Principles of Drug Action and Rational Therapy (11.12 ECTS)
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1 MODULE 15: (11.12 ECTS) FK4141 Basic Pharmacotherapy Study Goals / Skills: Dr. I Ketut Adnyana Indonesian Language and English Lecture /2 h per week Study time in class: 32 h Study time at home: 64 h credits Registered to Undergraduate Programme in Pharmaceutical Science and Technology, Human Anatomy and Physiology 1 and 2, Pharmacology 1 and 2, Patophysiology Describe the basic concept of pharmacotherapy and pharmacotherapy of several degenerative diseases Skills: Examine therapy algorithm for treatment of diseases Design patient s spesific pharmacotherapy Introduction, bone and joint disorders: gout and hyperuricemia, osteoarthritis, rheumatoid arthritis, osteoporosis, treatment of cardiovascular disorders : arrhythmias, hypertension, hyperlipidemia, thromboembolism, dermatologic disorders :psoriasis and skin disorders, endocrinology disorders: diabetes mellitus and thyroid disorders, gastrointestinal disorders : constipation, diarrhea, GERD, nausea and vomiting peptic ulcer disease; hematologic disorders: anemia Written or oral exam Lecture Notes, Slides, Board, E Learning Literature: Wells, B.G., J.T. Dipiro, T.L. Scwang Hammer, C.W. Hamilton, Pharmacotherapy Handbook, McGraw Hill, New York, 2003 Dipiro, J.T, R.L. Talbert, G.C. Yee, G.R. Matzke, B.G. Wells, I.M. Posey, Pharmacotherapy Brune, L., Pharmacoherapie, Springer, Berlin, 2004
2 Subtitle: Semester: 6 FA3241 Pharmacology and Toxicology II Prof. Dr. Andreanus Andaja Soemardji Dr. Maria Immaculata Iwo Dr. I Ketut Adnyana Dr. Neng Fisheri Kurniati Afrillia Nuryanti Garmana, M.Si. Indonesian Compulsory Class, Semester 6 Lecture/ 2 hours per week Study times in class : 32 hours Study times at home : 64 hours Human Anatomy and Phisiology I & II, Pharmacology and Toxicology I, Immunology Describe the effect of drugs which target cardiovascular, circulatory, nervous, gastrointestinal, respiratory, excretory, and endocrine sytems Literature: Interaction between drugs and body; drug classes according to organ systems; drug action evaluation, pharmacology and toxicology nervous system's drugs, cardiovascular drugs, gastrointestinal drugs, respiratory drugs, excretatory drugs, endocrine drugs, hormone; drugs effecting autacoids and vitamins. Written exam, Assignment Lecture Notes, Slides, Board Hardman, J.G., et. al (eds.) : Goodman and Gilman s : The Pharmacologycal Basis of Therapentics, 10th ed., Mc Grawhill, new York, Mulller, E., Dinamika Obat, terjemahan, penerbit ITB, Bandung, Katzung, B.B., Basis and Clinical Pharmacology, Prentice Hall International Inc., 6th ed., London, 2004.
3 Lawrence, D.R., A.L. Bacharach, Evaluation of Drug Activities : Pharmacometrics, Academic Press, London, Smith, C.M., A.M. Reynard, Essential of Pharmacology, W.B. Saunders, Co., Philadelphia, Subtitle: FA4141 Pharmacology and Toxicology III Dr. Maria Imaculata Iwo Indonesian Lecture/ 2 hours per week Study times in class : 32 hours Study times at home : 64 hours Human Anatomy and Phisiology I & II Describe the effect of antineoplastic and antiinfective drugs History of chemotherapy, basic principles of prophylaxis and treatment of infectious and tumor diseases, mechanism of drug resistance, molecule target and mechanism of action of antibacterial, antifungi, antituberculosis, anthelmintic, antiprotozoa, antivirus, and antitumor, novel drug development and treatment of anti infective and antitumor. Written exam, Assignment Lecture Notes, Slides, Board
4 Literature: Brunton, L.L., J.S. Lazo, K.L. Parker, Goodman & Gilman s, The Pharmacological Basis of Therapeutics, 11 th ed., McGraw Hill, New York, 2006 Katzung, B.G., Basic & Clinical Pharmacology, 8 th ed. Lange Medical Book, Connecticut, Mycek, M.J., R.A., Harvey and Champe, Pharmacology, 2 nd ed., Lippincot, Raven, Philadelphia, FA4142 Practicum of Integrated Pharmacology Dr. Neng Fisheri Kurniati Indonesian and English Practicum/ 4 hours per week, Tutorial / 1 h per week Practicum in Laboratory : 48 hours Preparation : 48 hours Registered students to Undergraduate Programme in Pharmaceutical Science and Technology Describe the human anatomy and physiology, as well as the basic principles of in vivo and in vitro pharmacology activity testing Demonstrate in vivo and in vitro pharmacological activity testing Literature: Design pharmacological experiments Description of human anatomy and physiology, experimental animals handling, as well as in vivo and in vitro pharmacological activity testing. Pre test, Laboratory Report, Discusion, Final Test Laboratory Module, Board, Laboratory instruments Goodman, L.S., Gilman, A., The Pharmacological Basic of Therapeutica, 4th ed, The Macmillan Co., New York, Domer, F.R., Animal Experiment in Pharmacology Analysis, Thomas Springfield, III, USA, Nodine, J.H., Sieglar P.E., Animal and Clinical Pharmacology Technique in Drug Evaluation, Year Book Medical Publicer Inc., Chicago, Miya, T.S, Laboratory Guide in Pharmacology, 3rd ed., Burgers
5 Publishing Co., Mineapolis, Minni, USA, Turner, R.A., Screening Methods in Pharmacology, Academic Press, 1965, New York, hal Roitt, I., J.Brostoff, D. Male, Immunology, Glower Medical Publishing, New York, Mercial, R.A., and M.D. Rojas, Pathology of protozoal and helminthic disease (with clinical correlation), Willlian&Wilkins, Baltimore. Martini, F.H., et al., Fundamentals of Anatomy and Physiology, 4th ed., Prentice Hall, London, Wood,M.G., Laboratory Textbook of Anatomy and Physiology, Prentice Hall, New Jersey, Tortora,G.J. and N.P. Anagnostakos, Principles of Anatomy and Physiology, 4 th ed., Harper and Row Publ., New York, UFAW, The UFAW handbook on the care and management laboratory animal, 4th ed., Churchill livingston, Edinburgh, Great Britain, Nodine, J.H., Sieglar P.E., Animal and clinical pharmacology Technique in Drug evaluation, Year Book Medical Publisher Inc., Chicago,1964
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