27-28 May Naples, Italy

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1 INTERNATIONAL CONFERENCE PRELIMINARY PROGRAMME First world conference on luteinizing hormone in assisted reproductive technology May

2 Overview The role of luteinizing hormone (LH) during folliculogenesis has heightened curiosity for at least three decades. In particular, the scientific community is still divided over recognizing the relevance of LH containing drugs during controlled ovarian stimulation (COS). Availability of recombinant drugs has offered, for the first time, the opportunity to explore the role of the follicle stimulating hormone (FSH) and luteinizing hormone (LH) separately. Despite this opportunity, the role of recombinant LH is still a matter of debate. What recently emerged is that LH is actively able to improve the outcome of IVF in specific subgroup of patients, including advanced age women (>35 years old) and the so-called hypo-responders. The latter group is represented by subjects that, despite being young, having normal ovarian reserve, and being classified as nomonadotrophic, show slow and sub-optimal response to conventional FSH doses. It was estimated that the profile of ovarian response is evident in 10-12% of women undergoing COS. More interestingly, the increase in ongoing pregnancy rates in these two subgroups of women does not seem to be correlated with the number of oocytes, suggesting that improvement in oocyte quality and/or extragonadal effects of LH could be implicated. Although a growing body of evidence is defining the role of LH during COS, clear guidelines and practical recommendations on this aspect are lacking. This conference will show evidence from basic science to clinical practice regarding the use of recombinant LH and will illustrate its possible benefits as well as its physiopathological mechanism. Guided by an expert, participants will grasp the rationale for using recombinant LH in assisted reproductive technology as well as understand the role of LH in human reproduction. Learning objectives By attending this live educational conference, participants will be able to: Understand the physiology of LH and its role in ovulation induction Grasp the state of the art regarding the use of recombinant LH use Individualise groups of patients that required LH during stimulation protocols Identify specific ovarian reserve markers and genotype polymorphism useful for tailoring treatments and choosing the best approach Target audience This programme is intended for clinicians, embryologists, biologists and scientists working in ART. 1

3 Honorary President Giuseppe De Placido University of Naples " Federico II" Naples Chairs Carlo Alviggi University of Naples " Federico II" Naples Sandro C. Esteves ANDROFERT - Andrology & Human Reproduction Clinic São Paulo, Brazil Local scientific committee Coordinator Ida Strina University of Naples " Federico II" Naples Luisa Avino University of Naples " Federico II" Naples Alessandro Conforti University of Naples " Federico II" Naples Pasquale De Rosa University of Naples " Federico II" Naples Silvia Picarelli University of Naples " Federico II" Naples Roberta Vallone University of Naples " Federico II" Naples 2

4 CME Provider EXCEMED is a non profit foundation dedicated, since the last four decades, to the development of high-quality medical education programme all over the world. EXCEMED adheres to the guidelines and standards of the European Accreditation Council for Continuing Medical Education (EACCME ) which states that continuing medical education must be balanced, independent, objective, and scientifically rigorous. Continuing medical education An application has been made to the EACCME for CME accreditation of the EXCEMED conference First world conference on luteinizing hormone in assisted reproductive technology to be held on May 2016 in. The CME conference First world conference on luteinizing hormone in assisted reproductive technology to be held on May 2016 in will be submitted for CME accreditation from the Italian Ministry of Health. EXCEMED adheres to the principles of the Good CME Practice group (gcmep). 3

5

6 Faculty

7 Carlo Alviggi University of Naples " Federico II" Naples Claus Yding Andersen University Hospital of Copenhagen Copenhagen, Denmark Manish Banker Nova IVI Fertility Pulse Women's Hospital Gujarat, India Ernesto Bosch Instituto Valenciano de Infertilidad Valencia, Spain Klaus Bühler Centre for Gynaecological Endocrinology and Reproductive Medicine Stuttgart, Germany Nicola Colacurci Outpatient Fertility Clinic Second University of Naples Sandro C. Esteves ANDROFERT - Andrology & Human Reproduction Clinic São Paulo, Brazil Renato Fanchin Hospital A. Béclère and University Paris-Sud Clamart, France Annapia Ferraretti SISMeR, Società Italiana Studi di Medicina della Riproduzione Bologna, Italy Robert Fischer Fertility Centre Hamburg Hamburg, Germany Ilpo Huhtaniemi Institute of Reproductive and Developmental Biology Hammersmith Campus, Imperial College London London, UK 6

8 Peter Humaidan Fertility Clinic Skive Regional Hospital, and Faculty of Health Aarhus University Aarhus, Denmark Antonio La Marca University of Modena and Reggio Emilia and Clinica Eugin Modena, Italy Raoul Orvieto The Chaim Sheba Medical Center Tel Hashomer, Israel Nikolaos Polyzos Vrije Universiteit Brussel Center for Reproductive Medicine Universitair Ziekenhuis Brussel Brussels, Belgium Eleonora Porcu University of Bologna Bologna, Italy Manuela Simoni University of Modena and Reggio Emilia Modena, Italy Marc-André Sirard Centre de Recherche en Biologie de la Reproduction Laval University Québec, Canada Sesh K. Sunkara Aberdeen Fertility Centre Aberdeen Maternity Hospital Aberdeen, UK Fulvio Zullo Reggio Calabria University Catanzaro, Italy 7

9 Programme

10 Programme Friday, 27 May 2016 From Registration Welcome Lunch EXCEMED Opening R. Fischer (Germany) Local Welcome G. De Placido (Italy) Introduction C. Alviggi (Italy) - S.C. Esteves (Brazil) Session I Taking off from basic science Chairs: E. Porcu (Italy) - M.-A. Sirard (Canada) L1: Physiology of LH and differences with hcg M. Simoni (Italy) L2: Polymorphisms of LH and its receptor I. Huhtaniemi (UK) L3: Facts and myths on the Liasons dangerous between LH and Progesterone C.Y. Andersen (Denmark) Panel Discussion Coffee break Legend: L : Lecture; 9

11 Session II Flying through literature... Chairs: R. Fisher (Germany) - F. Zullo (Italy) L4: Is there a role for LH in elderly patients? E. Bosch (Spain) L5: LH in low prognosis patients C. Alviggi (Italy) L6: LH in antagonist cycles; is the story really written? R. Orvieto (Israel) Panel Discussion End of the first day 10

12 Saturday, 28 May 2016 Session III Landing in the real world Chairs: A. La Marca (Italy) - S.K. Sunkara (UK) L7: The European point of view K. Bühler (Germany) L8: The Indian point of view M. Banker (India) L9: The Latin America approach S. C. Esteves (Brazil) Panel discussion Coffee break Session IV What about next flights Chairs: A. Ferraretti (Italy) - N. Colacurci (Italy) L10: The flip side of LH R. Fanchin (France) L11: ESHRE Bologna criteria: where are we? N. Polyzos (Belgium) L12: Matching patient and protocols in low prognosis; is it possible? P. Humaidan (Denmark) Panel discussion Concluding remarks End of the conference Closing lunch 11

13 General information Venue This conference will take place at the: Royal Continental Hotel Via Partenope, 38/ Napoli Language The official language of this conference will be English. CME Provider EXCEMED - Excellence in Medical Education Senior Programme Manager: Chloé Xilinas T F chloe.xilinas@excemed.org Medical Advisor: Alessandro Conforti confale@hotmail.it 12

14 Registration fee The registration fee is 350,00 and includes: Scientific sessions Coffee breaks and luncheons Dinner on 27 May 2016 Educational materials Certificate of attendance Event Planet srl Project Coordinator: Morena Trematerra Paola Federico Tel: +39 (0) Fax: +39 (0) LH2016@eventplanet.it Visit 13

15 Keep in touch excemed---excellence-in-medical-education 14

16 Take a look at the new website ONCOLOGY NEUROLOGY CARDIOMETABOLIC REPRODUCTIVE MEDICINE SPECIALTY IMMUNOLOGY ENDOCRINOLOGY AND METABOLISM AREA LIVE EVENTS LEARNING RESOURCES ONLINE COURSES NEWS AN EXCLUSIVE FOCUS ON CME Our core mission is to help physicians achieve the best possible outcomes for patients. Our name, EXCEMED, symbolizes a drive for excellence and reflects a passion for delivering the absolute best in CME. With four decades of achievement behind us and access to the world s premiere medical experts, better outcomes for patients start here. About EXCEMED. Six specialty areas, including reproductive medicine Accessible and accredited e-learning packages A world-class repository of CME knowledge and learning materials Monthly updates about our events and resources in reproductive medicine Register with us online and access it all free Better outcomes for patients start here. With over 40 years in the field, EXCEMED has been delivering CME-accredited programmes longer than any other provider in Europe, and now offers CME worldwide. 15

17 All EXCEMED programmes are organised solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to an educational grant received from Merck KGaA, Darmstadt, Germany. 16

18 Improving the patient's life through medical education EXCEMED - Excellence in Medical Education Headquarters 14, Rue du Rhône Geneva, Switzerland Representative Office Salita di San Nicola da Tolentino 1/b Rome, Italy T F Copyright EXCEMED, All rights reserved.

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