Ho Huynh Quang Tri Heart Institute

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1 EXCEMED Blended Education Cardiometabolic disorders in clinical practice: a comprehensive update Live intervention in PRELIMINARY PROGRAMME

2 Cardiometabolic disorders in clinical practice: a comprehensive update Overview Cardiometabolic disorders are the major cause of morbidity and mortality worldwide, and are intrinsically linked with diabetes, a devastating disease affecting more than 400 million people. Diabetes is the leading cause of cardiovascular disease, end-stage renal disease, blindness and nontraumatic lower-limb amputation, as well as negatively affecting pregnancy outcomes and the nervous system. However, diabetes and its complications can be avoided. A huge number of people suffer from initial alterations in glucose metabolism, known as "pre-diabetes". These people are at higher risk of developing overt diabetes in the coming years, but evidence shows the progression towards diabetes can be halted. Prompt intervention, with significant changes in lifestyle and/or implementation of appropriate pharmacotherapy, are effective strategies to prevent diabetes in at-risk people. To facilitate this, healthcare professionals should be updated with the most recent and compelling evidence about diabetes prevention. For those with overt diabetes, relentless effort should be expended to avoid the debilitating complications of the disease and to increase life expectancy. Knowledge and understanding of the complex pharmacological mechanisms and their clinical implementation will facilitate successful management of diabetes. Like diabetes, thyroid disorders are among the most prevalent endocrine diseases that also impact cardiovascular homeostasis. Unfortunately, a great number of patients with thyroid diseases are undiagnosed, contributing to increased morbidity and reduced quality of life. Therefore, there is a need for clear recommendations allowing for effective and prompt recognition of the most frequent thyroid disorders in order to adequately treat patients and avoid adverse clinical outcomes. Finally, hypertension is still the primary cause of death in the world and medicine is far from establishing adequate control of this cardiovascular risk factor. Recently, new aggressive targets for antihypertensive treatment were proposed, but it is not clear if scientific evidence justifies this therapeutic strategy. Additional discussion surrounds the issue of applying the results of controlled clinical trials to daily life. The role of combination treatment in hypertension and recent novelties in the availability of fixed dose formulations will also be discussed. An EXCEMED Learning Journey EXCEMED is involved in a comprehensive educational blended journey to increase knowledge in cardiometabolic diseases. This programme will address the most recent advancements of research in the areas of cardiometabolic medicine and will discuss the best approaches for clinical management of the complex cardiometabolic patient in daily practice. A multistep approach will be used, encompassing web-based and live activities. All activities in-person and online will involve the full interactivity of learners. Learning objectives By attending this programme, you will be able to: Implement the most cost-effective strategies for diabetes prevention Correctly diagnose thyroid disorders in the general population Identify specific blood pressure targets for each patient with hypertension Target audience This programme is designed for general practitioners, cardiologists, endocrinologists and internists managing diabetes and cardiometabolic diseases in the Asia-Pacific region. Chairs Nguyen Thy Khue University of Medicine and Pharmacy Ho Huynh Quang Tri Heart Institute 2 3

3 CME Provider EXCEMED is a non profit foundation dedicated, since the last four decades, to the development of highquality medical education programmes all over the world. EXCEMED adheres to the guidelines and standards of the European Accreditation Council for Continuing Medical Education (EACCME ) which states that continuing medical education must be balanced, independent, objective and scientifically rigorous. EXCEMED - Excellence in Medical Education Senior Programme Manager: Alessia Addessi T F alessia.addessi@excemed.org Medical Advisors: Ernesto Maddaloni and Stefano Taddei EXCEMED adheres to the principles of the Good CME Practice group (gcmep). Register now and receive the EXCEMED invitation to start your Learning Journey! INTERVIEW The first exclusive tutorial is an interview with Prof P. Pozzilli (Italy) which highlights the importance of diabetes prevention. This online educational tool is facilitated by the video-scribing technique and it enables to: understand the importance of an effective diabetes screening learn how to identify subjects at increased risk of diabetes LIBRARY The second exclusive tutorial helps illuminate the content of the live intervention, giving you the head start you need to be fully engaged during the in-person learning. You will also able to share your research and publications with the rest of the community using the library platform, and submit questions directly to faculty ahead of the live intervention. You can look forward to your question being addressed by faculty during theliv Q&A sessions. Features of the interactive library: Literature corner: summarises the key points and related publications for each of the lectures being presented during the live intervention in Ho Chi Minh City. Publications exchange: contains a section for learners to share their research and publications related to your Learning Journey. Question time: a chance for leaners to submit a question for the faculty to answer during the live intervention. 4 5

4 The live component of the Learning Journey is a combination of frontal lectures followed by interactive Q&A sessions, case-study-based debates, interactive clinical cases and working groups. You will be notified by when the video lectures, slide kits and a scientific highlights publication from the live intervention are available online. LEARNING OBJECTIVES By attending this live educational conference you will be able to: Acquire knowledge about the obesity and pre-diabetes emergency Personalize diabetes treatment Manage most prevalent thyroid disorders Tailor the appropriate treatment in hypertensive patients Venue This conference will take place at the: Intercontinental Saigon hotel Hai Bà Trưng, Bến Nghé, Quận 1 Continuing medical education The Cardiometabolic disorders in clinical practice: a comprehensive update, Ho Chi Minh City, Vietnam, 08/09/ /09/2018 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME ) with 9 (nine) European CME credits (ECMEC s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits TM. Information on the process to convert EACCME credit to AMA credit can be found at Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME for ECMEC s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada. Language The official language of the live intervention will be English. 6 7

5 FACULTY George Kahaly Department of Medicine Gutenberg University Medical Center Mainz, Germany Nguyen Thy Khue University of Medicine and Pharmacy Ernesto Maddaloni University Campus Bio-Medico (UCBM) Rome, Italy Giuseppe Mancia University of Milano-Bicocca Milan, Italy Mafauzy Mohamed University Sains Malaysia Health Campus Kelantan, Malaysia Nemencio A. Nicodemus Jr Department of Medicine University of the Philippines-College of Medicine Manila, Philippines Dang Van Phuoc Vietnam National University School of Medicine Paolo Pozzilli University Campus Bio-Medico (UCBM) Rome, Italy Ho Huynh Quang Tri Heart Institute Kun-Ho Yoon Department of Endocrinology & Metabolism Seoul St. Mary's Hospital Seoul, Korea PROGRAMME Saturday, 8 September Welcome and introduction N.T. Khue and H.H.Q. Tri (Vietnam) Session I L1: The diabetes pandemic E. Maddaloni (Italy) L2: Metabolic and clinical changes of pre-diabetes P. Pozzilli (Italy) L3: How to recognize people with pre-diabetes K.H. Yoon (Korea) Discussion Coffee break Session II L4: Obesity a contemporary issue creating future problems N.T. Khue (Vietnam) L5: Keywords for pre-diabetes management P. Pozzilli (Italy) L6: Is treatment of pre-diabetes cost-effective? M. Mohamed (Malaysia) Discussion Lunch Why you should worry about pre-diabetes, and how to recognize it Treating pre-diabetes Legend: L : Lecture : Case presentation : Discussion : Working groups 8 9

6 Sunday, 9 September 2018 Session III Diabetes treatment debate different patients, different solutions Session V Management of hypertension Case study 1: Newly diagnosed type 2 diabetes Case presentation Start with lifestyle intervention only K.H. Yoon (Korea) Immediately start with drug therapy P. Pozzilli (Italy) Discussion Case study 2: Frail elderly? patient with type 2 diabetes Case presentation Intensify monotherapy M. Mohamed (Malaysia) Add-on therapy E. Maddaloni (Italy) Discussion Coffee break Session IV Thyroid disorders: diagnosis is key Case study 3: Subclinical hypothyroidism G. Kahaly (Germany) Case study 4: Hypothyroidism during pregnancy G. Kahaly (Germany) L7: Blood pressure targets in hypertensive patients: European guidelines G. Mancia (Italy) L8: Are blood pressure targets proposed after the SPRINT study realistic in clinical practice? D.V. Phuoc (Vietnam) L9: New possibilities for fixed-dose combination treatment in hypertension H.H.Q. Tri (Vietnam) Discussion Coffee break Session VI Working groups on hypertension management This session includes two different parallel workshops, each lasting 1 hour. Participants will be divided into groups and will attend both workshops in rotation. By the end of the session each participant will have attended both workshops. WG1: Complex patient with hypertension: when a beta-blocker is needed H.H.Q. Tri (Vietnam) WG2: Complex patient with hypertension: when combination therapy is needed D.V. Phuoc (Vietnam) Back to plenary and take-home messages from the working groups End of the live educational conference Case study 5: Thyroid cancer N.A. Nicodemus (Philippines) End of the first day 10 11

7 TUTORIAL Registration Continue your Learning Journey after the live intervention! Online tutorials following the live intervention will help you delve deeper into content and put the key messages of this Learning Journey into clinical practice. CONCEPT MAP This in-depth tutorial will help you summarize the key points of the Learning Journey and turn scientific concepts into a visual format. Concept mapping will be facilitated through the video scribing and will offer you a representative summary of the entire learning path. VIDEO-LECTURE The final online tutorial is a video contribution by Prof. S. Taddei (Italy) on blood pressure targets after SPRINT study. The following topics will be addressed in this talk: Limitations of blood pressure targets in hypertension defined by Guidelines Evidence in favour of lower blood pressure values Strong and weak aspects of SPRINT The registration fee for the whole blended programme is EURO 225,00 and includes: Access to the online tutorials Scientific sessions Coffee breaks and lunch Educational materials Certificate of attendance Dinners are not included For registration, accommodation and any logistic inquiry, please contact: Meridiano Congress International Event Manager: David H. Slangen T F david.slangen@meridiano.it Visit Follow us on 12 13

14 All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted.

8 14 All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of EXCEMED. This independent programme is made possible thanks to educational grants received from: Merck KGaA Darmstadt Germany and San Raffaele Hospital Milan.

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Target audience. Jorge Correale Department of Neurology Raúl Carrea Institute for Neurological Research (FLENI) Buenos Aires, Argentina

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