28 June Munich, Germany

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Darleen Baldwin
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1 PRELIMINARY PROGRAMME 7th Advanced course in embryology 28 June Munich, Germany

2 Aim The 2014 live educational course will be dedicated exclusively to the most important aspects of ART laboratory procedures, providing a comprehensive view of advanced techniques. One of the topics is embryo culture media. The fundamental role of the laboratory and therefore the culture media has been to support preimplantation embryo development and to maintain the inherent viability of the gametes/embryos before replacement to the mother. Over the last years there have been major advancements in this area, with culture media having developed from simple salt solutions into highly complex defined media, specifically designed to reduce stress to the embryo and maintain high pregnancy rates. Preimplantation Genetic Screening (PGS) seeks to improve the efficiency of ART by ensuring that the embryos chosen for transfer are chromosomally adequate (diploid). The principle behind it is that, since numerical chromosomal abnormalities in the embryo are the causes of most pregnancy losses, and it is established that a large proportion of the human embryos are aneuploid, the selective replacement of diploid embryos should increase the chances of a successful IVF treatment. Future prospectives are based on SET (single embryo transfer) that needs to be adopted as standard procedure, in order to reduce risks to mother and fetus associated with multiple implantations. Methods for selecting topquality embryos must continue to improve and must be communicated through embryologist education. Criteria and scoring for assessing embryo quality need to be firmly established and followed internationally. The aim is to give participants both the latest knowledge and the opportunity to share their experiences with renowned scientists and embryologists. Learning objectives After attending this live educational course learners will be able to: Understand the role of culture media Learn how to optimize embryo culture Improve and acquire knowledge in preimplantation genetic testing techniques Gain knowledge on novel assessments on top-quality embryos to transfer Target audience Expert biologists and embryologists working in assisted reproductive medicine seeking the latest information about advanced techniques and scientific innovation. 1

3 Accreditation An application will be made to the EACCME for CME accreditation of the 7 th Advanced course in embryology" to be held on 28 June 2014 in Munich, Germany. Serono Symposia International Foundation (SSIF) adheres to the principles of the Good CME Practice Group (gcmep). Register to Serono Symposia International Foundation website: follow us on SSIF_RM 2

5 Scientific organisers Robert Fischer Fertility Center Hamburg Hamburg, Germany Zsolt Peter Nagy Scientific Director at Reproductive Biology Associates (RBA) Scientific Director of MEB-NA Atlanta, GA, USA Secretary and Chair-Elect, ALPHA, Scientists in Reproductive Medicine Serono Symposia International Foundation developed this programme in collaboration with: ALPHA, Scientists in Reproductive Medicine. We value your opinion! We are continually trying to develop and improve our educational initiative to provide you with cutting-edge learning activities. During this course you will be asked to answer a real-time survey and after this educational event you will be receiving an online survey to help us to better tailor our future educational initiatives. We thank you for participating! Scientific secretariat Serono Symposia International Foundation Salita di San Nicola da Tolentino, 1/b Rome, Italy Programme Manager: Simona Gaudiosi T +39-(0) F +39-(0) info@seronosymposia.org Medical Advisor: Irene Zerbetto Serono Symposia International Foundation is a Swiss Foundation with headquarters in 14, Rue du Rhône, 1204 Geneva, Switzerland Organising secretariat Meridiano Congress International Via Sapri, Rome, Italy Congress Coordinator: David H. Slangen T +39 (0) F +39 (0) d.slangen@meridiano.it 4

6 Faculty members

7 Claus Yding Andersen Laboratory of Reproductive Biology Juliane Marie Centre for Women, Children and Reproduction University Hospital of Copenhagen Faculty of Health Science University of Copenhagen Copenhagen, Denmark Natalia Basile Laboratorio FIV IVI Madrid Madrid, Spain Michele Boiani Max Planck Institute for Molecular Biomedicine Münster, Germany Robert Fischer Fertility Center Hamburg Hamburg, Germany Aaron J.W. Hsueh Division of Reproductive and Stem Cell Biology Department of Obstetrics and Gynecology Stanford University School of Medicine Stanford, USA Sebastiaan Mastenbroek Center for Reproductive Medicine Academic Medical Center University of Amsterdam Amsterdam, The Netherlands Zsolt Peter Nagy Scientific Director at Reproductive Biology Associates (RBA) Scientific Director of MEB-NA Atlanta, GA, USA Secretary and Chair-Elect, ALPHA, Scientists in Reproductive Medicine 6

8 Arne Sunde Department of Laboratory Medicine Children s and Women s Health Norwegian University of Science and Technology Trondheim, Norway Evelyn E. Telfer Reproductive Biology The University of Edinburgh Institute of Cell Biology and Centre for Integrative Physiology Edinburgh, UK Dagan Wells Institute of Reproductive Sciences Oxford, UK 7

9 Scientific programme

10 Scientific programme Saturday, 28 June Registration Serono Symposia International Foundation (SSIF) welcome R. Fischer (Germany) Session I Culture media Real-time survey L1: Implementation of a modern culture medium: one-step or sequential? A. Sunde (Norway) L2: Embryo kinetics in different culture environment - How to optimize embryo selection using different culture medium N. Basile (Spain) L3: The effect of culture conditions on the embryo and offspring: Do we have to worry? M. Boiani (Germany) Revisiting the real-time survey & question time Coffee break Legend: L : Lecture; D : Debate; D : Debate; 9

11 Session II Embryo selection L4: Novel technology to improve embryo selection Z.P. Nagy (USA) L5: Preimplantation genetic testing techniques: technical advances and expanding applications Speaker to be announced Question time Debate on: Will pregnancy rate improve with recent developments in PGS? Real-time survey D1: Support the motion D. Wells (UK) D2: Against the motion S. Mastenbroek (The Netherlands) Questions from the moderator Debaters concluding remarks D. Wells (UK) - S. Mastenbroek (The Netherlands) Revisiting the real-time survey Lunch 10

12 Session III Scientific breaktroughs Real-time survey L6: Egg precursor cells and mitochondrial transfer E.E. Telfer (UK) L7: New therapeutic intervention in primordial follicle recruitment A.J.W. Hsueh (USA) L8: Fertility restoration after ovarian tissue cryopreservation C.Y. Andersen (Denmark) Revisiting the real-time survey & question time Concluding remarks and take home messages 11

13 General information Venue This live educational course will take place at the: Sheraton Munich Arabellapark Hotel ArabellaStrasse 5, Munich 81925, Germany Phone: (49)(89) Fax: (49)(89) arabellaparkmuenchen@sheraton.com Language The official language of this live educational course will be English. Registration fees Registration fee is A 150,00. Registration fee for young physicians, up to 35 years old, is A 125,00. These fees include: Scientific sessions Coffee breaks and luncheons Educational materials Certificate of attendance For any registration and/or accommodation need please contact: David H. Slangen c/o Meridiano Congress International T: +39 (0) F +39 (0) d.slangen@meridiano.it All Serono Symposia International Foundation programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This programme is made possible thanks to educational grants received from: Arseus Medical, Besins Healthcare, Bristol-Myers Squibb, Celgene, Centre d Esclerosi Multiple de Catalunya (Vall d Hebron University Hospital), Centre Hépato-Biliaire (Hôpital Paul Brousse), Croissance Conseil, Cryo-Save, Datanalysis, Dos33, Esaote, Ferring, Fondazione Humanitas, Fundación IVI, GE Healthcare, GlaxoSmithKline Pharmaceuticals, IPSEN, Italfarmaco, International Society for Fertility Preservation, Johnson & Johnson Medical, K.I.T.E., Karl Storz, Lumenis, Merck Serono Group, PregLem, Richard Wolf Endoscopie, Sanofi-Aventis, Stallergenes, Stopler, Teva Pharma, Toshiba Medical Systems, Université Catholique de Louvain (UCL), University of Catania. 12

Take a look at the reproductive medicine section of SSIF website Infertility issues have been significant in developed countries for some time and are now becoming relevant across much of the world.

Infertility also has ethical, social and economic implications, which have generated heated debates among experts.

14 Take a look at the reproductive medicine section of SSIF website Infertility issues have been significant in developed countries for some time and are now becoming relevant across much of the world. Besides being a challenging medical problem, infertility can also have profound psychological effects. Infertility also has ethical, social and economic implications, which have generated heated debates among experts. Reproductive health, the branch of medicine concerned with infertility treatments is continually exploring new techniques to address the problem. Healthcare professionals working in this field need access to regular updates and training. Serono Symposia International Foundation (SSIF) realized the importance of developing medical education in this area at an early stage and pioneered the first symposium in reproductive medicine more than 30 years ago. From this beginning to the present day, SSIF has offered high-level educational events, ranging from training for young specialists to updating scientists on advanced areas of research. Our mission is to provide quality medical education such as we offer, available worldwide. Visit the reproductive medicine section: and register to access free e-learning activities and receive updates on new events and resources.

With thanks for the collaboration to www.agrbm.

org Serono Symposia International Foundation Headquarters 14, Rue du Rhône - 1204 Geneva, Switzerland

15 With thanks for the collaboration to Improving the patient's life through medical education Serono Symposia International Foundation Headquarters 14, Rue du Rhône Geneva, Switzerland Representative Office Salita di San Nicola da Tolentino 1/b Rome, Italy T +39.(0) F +39.(0) Copyright Serono Symposia International Foundation, All rights reserved.

International medical oncologists, surgeons and radiation oncologists experienced in the management of head and neck cancer patients.

International medical oncologists, surgeons and radiation oncologists experienced in the management of head and neck cancer patients. Aim of the educational preceptorship Treatment options for patients with unresectable head and neck cancer have been significantly expanded over the last few years. Combined modality treatment with concomitant