Trial: OMEGA-3s May Help Sustain Muscle

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1 JUNE 2015 Trial: OMEGA-3s May Help Sustain Muscle Findings from a clinical trial reported online on May 20, 2015 in the American Journal of Clinical Nutrition reveal improvements in muscle mass and function in adults supplemented with omega-3 polyunsaturated fatty acids (PUFA) in comparison with a placebo group. The trial results were published online in the online newsletter Life Extension Update, published by Life Extension, an organization that researches health and aging. Gordon I. Smith and colleagues note in their introduction to the article that while numerous studies show omega-3 PUFAs benefit people with serious illness, robust assessment of their effects on muscle mass and function in the older adult population has not been made. Researchers at Missouri s Washington University School of Medicine randomized 60 men and women between the ages of 60 and 85 years to receive supplements containing a total of 1.86 grams eicosapentaenoic acid (EPA) and 1.5 grams docosahexaenoic acid (DHA), or a placebo daily for six months. In addition to blood omega-3 levels and other factors, thigh muscle volume, handgrip strength, one-repetition maximum upper and lower body strength, and average isokinetic muscle power were evaluated at the beginning of the study, at three months (with the exception of thigh muscle volume) and at the end of the treatment period. After six months, red blood cell omega-3 levels had increased by 135 percent among those who received the fatty acids while remaining unchanged in the placebo group. Thigh muscle volume, handgrip strength and one-repetition maximum muscle strength were significantly increased in omega-3 fatty acid supplemented participants in comparison with the control group at six months. Average isokinetic muscle power also showed a tendency toward improvement after six months in the omega-3 group. OMEGA 3 Results from our study show that fish oil-derived omega-3 PUFA therapy has clinically important muscle anabolic and physical performance-enhancing effects in older adults, the authors conclude. As people age, they sometimes develop sarcopenia (from the Greek meaning poverty of flesh ), which generally refers to age-related loss of muscle mass and function. Approximately 50 percent of people over age 80 experience sarcopenia, according to the article. Consumption of sufficient amounts of omega-3 fatty acids is helpful in preventing and treating this catabolic wasting, according to the Life Extension article. Omega-3 fatty acids are found in high concentrations in certain fatty fish/fish oil and flaxseed/flax oil.

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