16 Nuchal Fibroma and Gardner

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1 C O N T E N T S Dedication v Preface vii Acknowledgments ix SECTION 1 Fibrohistiocytic Tumors 1 1 Classification of Fibrohistiocytic Tumors 3 2 Dermatofibroma 5 3 Juvenile Xanthogranuloma Solitary Reticulohistiocytoma and Multicentric Reticulohistiocytosis 43 Acrochordons and Pendulous Fibromas 49 Cutaneous Solitary Fibrous Tumor 56 7 Sclerotic Fibroma (Storiform Collagenoma) Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) 68 Desmoplastic Fibroblastoma (Collagenous Fibroma) Pleomorphic Fibroma of the Skin Fibroma of Tendon Sheath Giant Cell Tumor of Tendon Sheath Cutaneous Myxoma Superficial Acral Fibromyxoma Cellular Digital Fibroma Nuchal Fibroma and Gardner Syndrome Associated Fibroma Cerebriform Collagenoma Associated with Proteus Syndrome 103 Elastofibroma 107 Nodular Fasciitis, Proliferative Fasciitis, and Ischemic Fasciitis 111 Fibromatosis 117 Juvenile Hyaline Fibromatosis 127 Fibrous Hamartoma of Infancy 131 Calcifying Aponeurotic Fibroma Dermatofibrosarcoma Protuberans Angiomatoid Fibrous Histiocytoma Plexiform Fibrohistiocytic Tumor Soft Tissue Giant Cell Tumor of Low Malignant Potential Inflammatory Myofibroblastic Tumor Inflammatory Myxohyaline Tumor of Distal Extremities Atypical Fibroxanthoma Malignant Fibrous Histiocytoma Fibrosarcoma Epithelioid Sarcoma 198 xi

2 xii 34 Synovial Sarcoma Alveolar Soft Part Sarcoma 215 SECTION 2 Myofibroblastic and Muscle Tumors Myofibroblasts, Muscle Cells, and Classification of Skin Proliferations with Myofibroblastic and Muscle Differentiation Infantile Myofibromatosis Infantile Digital Fibromatosis Cutaneous Myopericytoma (Adult Cutaneous Myofibroma) 232 Cutaneous PEComa 240 Dermatomyofibroma (Plaque-Like Dermal Fibromatosis) Genital Angiomyofibroblastoma Myofibroblastic Sarcoma 252 Smooth Muscle Hamartoma 254 Piloleiomyoma 259 Angioleiomyoma Cutaneous Angiolipoleiomyoma Leiomyomas of the External Genitalia Cutaneous Leiomyosarcoma Striated Muscle Hamartoma (Rhabdomyomatous Mesenchymal Hamartoma) Extracardiac Rhabdomyoma Cutaneous Rhabdomyosarcoma 293 SECTION 3 Vascular Tumors Histology of Cutaneous Vascularization and Classification of Cutaneous Vascular Anomalies 305 Phakomatosis Pigmentovascularis 316 Eccrine Angiomatous Hamartoma 321 Nevus Anemicus 327 Cutis Marmorata Telangiectatica Congenita 329 Salmon Patch and Port-Wine Stain or Nevus Flammeus 335 Cutaneous Venous, Glomus, and Arteriovenous Malformations 346 Cutaneous Lymphatic Malformations Vascular Spider (Nevus Araneus) Caliber-Persistent Artery Capillary Aneurysm and Venous Lake Telangiectases Angiokeratomas Verrucous Hemangioma Lymphangiectases Angiolymphoid Hyperplasia with Eosinophilia Pyogenic Granuloma Bacillary Angiomatosis Verruga Peruana 425

3 xiii 72 Cutaneous Epithelioid Angiomatous Nodule Reactive Angioendotheliomatosis Intralymphatic Histiocytosis Intravascular Papillary Endothelial Hyperplasia (Masson Pseudoangiosarcoma) Pseudo-Kaposi Sarcoma Serpiginous Angioma Infantile Hemangiomas Senile Hemangioma Acral Arteriovenous Hemangioma Hobnail Hemangioma (Targetoid Hemosiderotic Hemangioma) 489 Microvenular Hemangioma 495 Tufted Hemangioma Glomeruloid Hemangioma Acquired Elastotic Hemangioma Sinusoidal Hemangioma Spindle Cell Hemangioma 518 Benign Lymphangioendothelioma 525 Atypical Postradiation Vascular Lesions of the Skin 530 Glomus Tumors 537 Kaposi Sarcoma 545 Kaposiform Hemangioendothelioma Papillary Intralymphatic Angioendothelioma (PILA) (Dabska Tumor) Retiform Hemangioendothelioma 580 Epithelioid Hemangioendothelioma Pseudomyogenic Hemangioendothelioma Composite Hemangioendothelioma 595 Cutaneous Angiosarcoma of the Face and Scalp in Elderly Patients (Wilson Jones Angiosarcoma) Cutaneous Angiosarcoma with Associated Lymphedema Postirradiation Cutaneous Angiosarcoma Epithelioid Angiosarcoma Malignant Glomus Tumor (Glomangiosarcoma) 636 Multinucleate Cell Angiohistiocytoma Angiofibroma Aggressive Angiomyxoma 653 Kimura Disease Pseudolymphomatous Angiokeratoma in Children 660 SECTION 4 Neural Tumors Histology, Ultrastructure, and Immunohistochemistry of Peripheral Nerves: Classification of Skin Tumors of Neural Origin 665

4 xiv 109 Neural Hamartomas Hyperplasia of Pacini Corpuscles Glial Heterotopia (Nasal Glioma) Meningeal Heterotopia (Cutaneous Meningioma) Neuromas Neurofibroma and Neurofibromatosis 719 Schwannoma 739 Granular Cell Tumor 755 Nerve Sheath Myxoma and Neurothekeoma 763 Perineurioma 773 Cutaneous Ganglioneuroma 782 Malignant Peripheral Nerve Sheath Tumor Primary Primitive Neuroectodermal Cutaneous Tumor Malignant Granular Cell Tumor 802 SECTION 5 Adipose Tumors Histology of Normal Subcutis and Classification of Adipose Proliferations 811 Piezogenic Papules 815 Nevus Lipomatosus Cutaneous Superficialis Fibrolipomatous Hamartoma of the Nerve Lipomas and Lipomatosis Angiolipoma Chondroid Lipoma Spindle Cell Lipoma/Pleomorphic Lipoma Lipofibromatosis Hemosiderotic Fibrolipomatous Tumor Lipoblastoma and Lipoblastomatosis Hibernoma Atypical Lipomatous Tumor/ Well-Differentiated Liposarcoma Undifferentiated Liposarcoma 870 SECTION 6 Cartilage Tumors Histology of Normal Cartilage and Classification of Cartilaginous Lesions of the Skin 883 Accessory Tragus 885 Extraskeletal Chondroma Subungual Osteochondroma (Subungual Exostosis) 892 SECTION 7 Ossifying Tumors Normal Bone Histology and Classification of Ossifying Lesions Presenting in the Skin 899 Osteoma Cutis 902

5 xv 143 Fibro-Osseous Pseudotumor of the Digits Ossifying Plexiform Tumor Ossifying Fibromyxoid Tumor Extraskeletal Osteosarcoma 915 SECTION 8 Myoepithelial Tumors Myoepithelioma and Myoepithelial Carcinoma 921 SECTION 9 Melanocytic Tumors Cutaneous Clear Cell Sarcoma 929 SECTION 10 Tumors of Unknown Histogenesis Primary Cutaneous Ewing Sarcoma 939 Index 945