2007 : Became Poultry Corporate Marketing Director. Ceva Sante Animale, France
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1 Dr. Sylvain Comte Poultry Corporate Marketing Director Ceva Sante Animale, France Graduated as a Veterinary in 1993 from National Veterinary School of Nantes France Master of science in Physiology and Agronomy from Rennes University France 1998 : Joined Ceva at R & D department, International technical manager, Head of Pharmaceutical Project 2003 : Regional Technical & Marketing Director Africa, Middle East and Indian Subcontinent 2007 : Became Poultry Corporate Marketing Director Topic : The Evolution of Poultry Vaccination
2 The Evolution of Poultry Vaccination i Dr Sl Sylvain COMTE, Poultry Corporate Marketing Director Head of Poultry Franchise Ceva Santé Animale France
3 Content All data : Ceva internal data Poultry Vaccination Practices Broiler Hatchery vaccination in 2011 New technologies Review of New technology vaccines 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in 2011 New field of possibilities
4 Content Poultry Vaccination Practices Broiler Hatchery Vaccination in 2011 New technologies Review of New technology vaccines 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in i 2011 New field of possibilities
5 2011 Hatchery Vaccination Practices ((In ovo & Day old y injection) j ) North America (Billion Broilers) Western EU (Billion Broilers) Central & Eastern Europe (Billion Broilers) 10 0 Hatchery At least 1 vacc. Field only Hatchery At least 1 vacc. Field only Hatchery At least 1 vacc. Africa & Middle East (Billion Broilers) Field only Asia (Billion Broilers) Latin America (Billion Broilers) 8 7 Hatchery At least 1 vacc. Field only ,5 Hatchery At least 1 vacc. 0 Hatchery At least 1 vacc. Field only Field only No hatchery vaccination Country Practicing Hatchery vaccination
6 2011 Hatchery Injection Practices 66 % of Global Broiler Production ( 100% Layers & Breeders) Global Poultry (Billi B (Billion Broilers) il ) 40 33,5 35 Global Poultry (Billion Broilers) Hatchery At least 1 vacc. vacc Field only % Hatchery At least 1 vacc. Field only 66%
7 Content Poultry Vaccination Practices Broiler Hatchery vaccination in 2011 New technologies Review of New technology Vaccines and Equipment Status 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in 2011 New field of possibilities
8 3 new vaccine generations since 2002 Live attenuated vaccines Immune Inactivated FP Vector Complex HVT Vector oily emulsion Vaccines Vaccines Vaccines vaccines Immune complex : The antigen is bound to specific antibodies that protect it from the host recognition system and action of MDA. The antigen is released exactly at the right time on an individual bird per bird basis. Today s application for IBD control in broilers : In ovo or Day old, 1 injection for life long immunisation
9 3 new vaccine generations since 2002 Live attenuated vaccines Immune Inactivated FP Vector Complex HVT Vector oily emulsion Vaccines Vaccines Vaccines vaccines FP and HVT Vector Vaccines : FP or HVT conventional virus, genetically engineered, expressing an other disease key protective antigens. Vector viruses are selected for : low MDA susceptibility, very good safety for In ovo or day one administration and life long immunity rfp LT rfp MG rfp AIV rfp NDV rhvt NDV rhvt LT rhvt IBD rhvt AIV 7 diseases are covered today
10 Hatchery & Farm Vaccination equipment 2011 In ovo injection Day old injection Spray injection Tools Status 2011 Automatic & Semi Automatic equipment Single Injector Double Injector Semi automatic Robot El t i I j t Existing Existing Existing Existing 2014 Electronic Injector 2014 Hatch Cabinet In Line Sprayer Existing Existing Spray in cages 4 & 6 Cage Sprayers Existing IM Injection AutomaticPulletIM Existing Wing Web injection Fowl Pox Injector Existing 10
11 Content Poultry Vaccination Practices Broiler Hatchery vaccination in 2011 New technologies Review of New technology vaccines 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in 2011 New field of possibilities
12 2011 IBD Immune Complex Usage 0% in % in 11.5 i 2011 off Total T l Broiler B il Population P l i Impossible d'afficher l'image. Votre ordinateur manque peut-être de mémoire pour ouv rir l'image ou l'image est endommagée. Redémarrez l'ordinateur, puis ouv rez à nouv eau le fichier. Si le x rouge est toujours affiché, v ous dev rez peut-être supprimer l'image av ant de la réinsérer. IBD Immune Complex vaccinated birds Billion birds 6,00 5,02 2,41 0, ,49 0, % 41% 1% 51% 3% 30% 8% 7% 9% 31 9% 29% 27% 2% 9% 2% 4% 9% 9% 12% 10% 9% 2% 17% 41% 30% 20% 19% 34% 16% 4% 8% 55% 38% 19% 6% 8% 33% 76%
13 2005 IBD Vaccination 2% Hatchery Vaccination against IBD % of Total Broiler Population Hatchery 98% Field New technology Vaccines : Immune Complex vaccines & Vector HVT IBD vaccines 2011 IBD Vaccination 25% Hatchery 75% Field 13
14 IBD Vaccination Practices per Geography 2010 Market Value for Hatchery or Field IBDV vaccines by Regions (M ) 45 Hatchery Vaccines 40 Farm Inter. 35 Farm Inter. Plus NORTH AMERICA ASIA A & ME LATIN AMERICA WESTERN EUROPE CENT EAST EUR & TURK
15 Content Poultry Vaccination Practices Broiler Hatchery vaccination in 2011 New technologies Review of New technology vaccines 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in 2011 New field of possibilities
16 14,0 12,0 10,0 8,0 6,0 4,0 2,0 0,0 ND & ILT Vaccination 2009 to 2011 Practices per Geography 2009 ND and ILT VaccinationPractices Billions Broilers 6,6 1,5 10,0 13,0 5,0 5,0 Conventional New Tech ILT New Tech NDV North Latin Africa & Asia Western EU Central & America America Middle East Eastern Europe 16,0 14,0 12,0 10,0 8,0 6,0 4,0 2,0 00 0,0 4, ND and ILT Vaccination Practices Billions Broilers 60 6,0 3,2 North America 9,4 Latin America 14,9 5,0 5,0 Africa & Middle East Conventional ND New Tech ILT New Tech NDV 4,0 Asia Western EU Central & Eastern Europe
17 New technology ND & ILT Vaccination 2009 to 2011 From 5 % in 2009 to 12 % in 2011 Global Poultry Population 2009 New Tech NDV New Tech ILT Conventional ND 3% 2% Global Poultry Population 2011 New Tech NDV New Tech ILT Conventional ND 8% 4% 95% 88%
18 Content Poultry Vaccination Practices Broiler Hatchery vaccination in 2011 New technologies Review of New technology vaccines 2011 Usage of New Technology vaccines against IBD in 2011 Usage of New Technology vaccines against ND an ILT in 2011 New field of possibilities: In Broilers In Layers and Breeders In management
19 Example : IBD and ND Vaccination in broilers Today we are able to combine in one shot at the hatchery in broilers: IBD protection ND protection MD protection with 1 IBD Immune Complex & 1 Vector HVT NDV Vaccines FP and LT protection can be added 3 to 5 major diseases in 1 hatchery administration
20 Vaccination Management Hatchery A team dedicated to vaccination : Control and organisation of the work Better control on Human factors Broiler houses in vaccination A large number of farmers and field conditions : IMPOSSIBLE control and organisation of the work
21 Age Vaccination Application method Day old Marek (HVT + Rispens) Injection ND killed Injection ND + IB live Spray Example of layer vaccination schedule Labor intensity Expect PVR/interference Day 10 ND + IB live Spray Day 21 Gumboro Drinking water Day 28 Gumboro Drinking water Week 6 MG live S. Gallinarum live ILT live ND Killed Eye drop Injection Eye drop Injection Week 8 ND + IB Live Spray Coryza Injection Week 10 AE + PO Salmonella killed Wing Web Injection Week 12 ND live + IB live Spray S. 12 Gallinarum diseases Live Injection Week 14 ND + IB live SprayI Coryza 20 + vaccination IB + ND +EDS Injection campaigns in 16 wks Sl Salmonella ll killed Injection Week 16 ND + IB live Spray 12 individual applications
22 Simplification Layers & Breeders Vaccination Age Vaccination Application method Labor intensity Expect PVR/interference Day old Vector HVT NDV + Rispens Injection O ND + IB live Spray Day 10 IB live Spray Day 21 Gumboro Drinking water Day 28 Gumboro Drinking water Week 6 Week 8 MG live S. Gallinarum live ND + IB Live Coryza & Se Combined Eye drop Injection Spray Injection Week 10 Vector FP LT Wing Web 0 12 diseases Week k12 ND + IB live Spray S. Gallinarum Live Injection Week vaccinations campaigns in 16 wks 20 % less campaigns ND + IB live Coryza IB ND EDS SE Spray Injection 8 individual applications 33% Less individual handling Week 16 ND + IB live Spray Less Stress Less Labor
23 In 2011 : 66% of Broilers and 100 % of Layers & Breeders are Hatchery vaccinated in 2011 IBD hth hatchery vaccination has grown from 0 to 25 % of the vaccinated birds in 5 years ND and ILT hatchery New tech vaccines have grown from 0 to 12% in 3 years New Technology Vaccines and Equipment are developping fast and started to be available everywhere in 2011 Conclusion New vaccines and Equipment offer a new field of possibilities is terms of : Increasing Vaccination program Efficiency (No MDA effect) and Safety (Less Live vaccines and perfect Safety) Increasing Vaccination Proactivity in case of epidemy Simplifying Work organisation and labour needs Simplifying Human Factor Management Decreasing Stress and Number of handling applied to birds
24 Thanks for your attention
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