The Academy for Clinical Debates & Controversies in Medicine Announces: 1 st World Congress on

Transcription

1 The Academy for Clinical Debates & Controversies in Medicine Announces: 1 st World Congress on Controversies in Psychiatry Berlin, Germany, June 18-21, 2009 Invitation to Industry Sponsorship and Exhibition Prospectus A comprehensive Congress fully devoted to clinical debates and controversial issues in a wide spectrum of psychiatric conditions

2 2 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Dear Friends and Colleagues, We take pleasure in inviting you to take part in The First World Congress on Controversies in Psychiatry (COPSY). We would be honored by your participation. During the Decade of the Brain, the field of Psychiatry has witnessed enormous expansion in clinical and basic data. This growth has created a greater need to debate the many controversial issues raised and translate them into clinical practice. This point is emphasized in light of the creation of the Neurosciences and the need to negotiate a unique place for Psychiatry in this domain. This is a Concept Congress that strives to promote true clinical discussion on unresolved pressing issues between practicing physicians and clinical researchers and allowing ample time for speakers-audience interaction. This CME approved Congress has the ability to reach real-life agreed-upon insights on a wide range of psychiatric issues even when the available data is incomplete. The Congress will highlight up-to-date, evidence-based medicine in Psychiatry, to be presented by internationally acclaimed experts. We look forward to your positive response. Your presence will create a greater forum dedicated to solving these controversial issues. Yours sincerely, Prof. Meir Steiner Prof. Julien Mendlewicz Prof. Joseph Zohar On behalf of the international Scientific Committee International Scientific Committee Meir Steiner, MD, PhD, FRCPC, Canada, Chairman Professor of Psychiatry & Behavioural Neurosciences and Obstetrics & Gynecology, McMaster University Professor, Department of Psychiatry and Institute of Medical Sciences Adjunct Scientist, The Hospital for Sick Children, Toronto, Founding Director, Women's Health Concerns Clinic St. Joseph's Healthcare Hamilton Julien Mendlewicz, MD, Ph.D, Belgium, Chairman Professor of Psychiatry, Free University of Brussels President of the European College of Neuropsychopharmacology (ECNP) Secretary General of the European Brain Council Joseph Zohar, MD, Israel, Chairman Director of Psychiatry A and Anxiety Clinic, Chaim Sheba Medical Center Professor of Psychiatry, Tel Aviv University Cyril Höschl, DrSc., FRCPsych., Czech Republic, Member President, European Psychiatric Association Director, Prague Psychiatric Centre affiliated with Charles University Prof. Dr. med. Hans-Jürgen Möller, Germany, Member Director Clinic for Psychiatry of the University of Munich Ludwigs-Maximilians Universität München Nussbaumstrasse, Munich Siegfried Kasper, MD, Austria, Member Department of Psychiatry and Psychotherapy Medical University Vienna, Wien

3 InterContinental Hotel, Berlin, Germany - June 18-21, Sections: Bipolar Disorders Head Guy Goodwin, MD, Ph.D., UK W.A.Handley Professor of Psychiatry Head, University Department, Warneford Hospital, Oxford Anxiety Disorders Head Eric Hollander, MD, USA Esther and Joseph Klingenstein Professor and Chair of Psychiatry Director, Seaver and NY Autism Center of Excellence Mount Sinai School of Medicine Women s Mental Health Head Susan G. Kornstein, MD, USA Professor of Psychiatry and Obstetrics and Gynecology, Virginia Commonwealth University Executive Director, VCU Institute for Women's Health President, International Association for Women's Mental Health Editor-in-Chief, Journal of Women's Health Members P. Blier, Canada E. Vieta, Spain L. Von Knorring, Sweden Members B. Bandelow, Germany B. Baldwin, UK D.J. Stein, South Africa Members A. Clayton, USA L. Cohen, USA Z. Dolev, Israel E. Eriksson, Sweden T. Pearlstein, USA C. Soares, Canada Local Organizing Committee Head Isabella Heuser, MD, Germany Professor of Psychiatry Chair of Psychiatry at the Medical School of the Charité Berlin Director of the Clinical and Research Unit of Psychiatry, Hospital Charité Berlin Members I. Anghelescu, Germany M. Bajbouj, Germany M. Huell, Germany G. Kronenberg, Germany A. M. Lindenberg, Germany D. Naber, Germany R. Rupprecht, Germany H.U. Wittchen, Germany

4 4 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Preliminary Program BIPOLAR DISORDERS PHENOTYPIC DIFFERENTIATION The boundaries of bipolar disorders are not well defined. Is it a single nosologic entity or a cluster of different syndromes? Bipolar disorder: Spectrum or nonspectrum? Early onset bipolar disorder - how does it differ from the late onset form? Brain imaging as a diagnostic and therapeutic tool Childhood Bipolar Disorder: Myth or Reality? Myth: The diagnosis of childhood bipolar disorder and its very existence is being questioned Reality: New studies indicate that childhood bipolar disorder is a real entity How to differentiate bipolar disorder from attention deficient hyperactiviy disorder (ADHD) in children? THERAPEUTIC INTERVENTIONS IN BIPOLAR DISORDERS (1) Various pharmacological approaches are available, but the complexity of bipolar disease renders optimal treatments problematic. What is the ideal mood stabilizer? Should we use second-generation antipsychotics as mood stabilizers? Should we use anti-epileptics as mood stabilizers? Individualised treatment: Is pharmacogenetics a reality or fantasy? THERAPEUTIC INTERVENTIONS IN BIPOLAR DISORDERS (2) Despite polypharmacy relapses of bipolar disease are frequent USA versus European guidelines for the treatment of bipolar disorder The place for psychosocial therapies Antidepressants Aggravate Bipolar Disorders Yes: No: Proposition: Should bipolar depression be treated differently from unipolar depression? Opposition: Bipolar and unipolar depressions should be treated similarly! UNIPOLAR DISORDERS PREDICTION OF TREATMENT-RESISTANT DEPRESSION (TRD) Approximately one-third of patients suffering from depression do not respond to adequate antidepressant treatment - can this be predicted? What are the predictors of TRD and how should it be managed? How should TRD be best defined? What are the clinical and neurobiological predictors? Therapeutic challenges of TRD Can we optimize achieving remission in depression? THE COMORBIDITY PUZZLE OF DEPRESSIVE DISORDERS The great majority of depressed patients suffer from other psychiatric and somatic disorders as well. Why is diagnosis so important? Psychiatric comorbidity Somatic comorbidity Therapeutic challenges of comorbid depression

5 InterContinental Hotel, Berlin, Germany - June 18-21, NOVEL APPROACHES TO TREATMENT OF DEPRESSION (I) Despite pharmacological advances, there is still a need to improve efficacy and tolerance of antidepressant therapies What is the place for novel antipsychotic drugs? Do antiepileptic drugs have a place in the treatment of depression? Chronopharmacological and chronobiological approaches - how strong is the evidence? NOVEL APPROACHES TO TREATMENT OF DEPRESSION (II) Despite pharmacological advances, there is still a need to improve efficacy and tolerance of antidepressant therapies Nonpharmacological approaches - do they still have a place? Monotherapy or Combination Therapy? Proposition: Combination therapy acts faster and more efficiently than monotherapy Opposition: Start with monotherapy then add! ANXIETY DISORDERS PREVENTION IN POSTTRAUMATIC STRESS DISORDER (PTSD) AN ILLUSION OR A DREAM COME TRUE? Can the well-accepted notion of "golden hours" (very early intervention which alters the course, e.g. in CVA etc.) be adopted in psychiatry and in the treatment of PTSD? Can PTSD be Prevented? Proposition: Insights gained from neuroscience suggest that early intervention may prevent PTSD Opposition: The emotional response to trauma is a normal response to an abnormal situation and no special intervention is needed In the aftermath of trauma exposure, what are the positive and negative procedures? COGNITIVE-BEHAVIORAL THERAPY (CBT) REVISITED Several guidelines (e.g. NICE) suggest CBT as a first-line option in treatment of anxiety disorders, and plummets pharmaceutical intervention to second place Can CBT Replace Psychopharmacological Therapy in Anxiety Disorders? Proposition: Should CBT be a first-line treatment in anxiety disorders? Opposition: Should psychopharmacological treatment remain a first-line treatment in anxiety disorders? Neuroscience, CBT and psychopharmacology: Can the treatment be tailored? ANXIETY DISORDERS TOWARD DSM-V AND ICD-11 WHAT WILL REMAIN AND WHAT WILL CHANGE Traditionally, anxiety disorders have been grouped together based on symptomatic presentation of "anxiety" Should Obsessive Compulsive Disorder (OCD) and Generalized Anxiety Disorders (GAD) Remain in Anxiety Disorders? Proposition: The data is not strong enough for radical changes Opposition: Neuroscience, epidemiological and genetic findings support division of anxiety disorders The concept of anxiety spectrums Stress-related disorders

6 6 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 TREATMENT RESISTANCE Treatment-resistant patients require more time in clinics and treatment remains controversial Switching vs. Augmentation Proposition: Clinical and theoretical background favours "switching" Opposition: Evidence and the "myths" of augmentation Treatment tailored to a specific patient CURRENT USE OF BENZODIAZEPINES (BNZ) BNZ have been widely used, but concern has also been raised regarding tolerance and withdrawal BNZ for Anxiety Why are They Coming Back? Proposition: We should keep using BNZ! Opposition: BNZ be abandoned! BNZ, half-life and addiction potential SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs) AND TRICYCLIC ANTIDEPRESSANTS (TCA) A SECOND LOOK Clinical experience with the use of TCA is diminishing - however, relinquishment may be too early Does TCA Play a Role in Modern Psychiatric Treatment? Proposition: Despite diminishing experience, TCAs are still relevant for treatment Opposition: TCAs should be disposed of and should be replaced by SSRIs The practicality of TCA use WOMEN S MENTAL HEALTH ANTIDEPRESSANT USE DURING PREGNANCY AND BREASTFEEDING Despite accumulating data suggesting the relative safety of antidepressants during the perinatal period, many clinicians are still reluctant to prescribe them Are antidepressants given during the perinatal period safe? Yes: No: Do safety issues differ in early or late pregnancy? What are the potential risks to the fetus and the newborn? How can a clinician make the best evidence-based, risk-benefit decision? GENDER AND DEPRESSION Evidence on gender differences in symptoms, prevention and treatment of depression is accumulating Does Female Depression Differ from Male Depression? Yes: No: Do clinical parameters for diagnosis, prevention and treatment vary? Are new diagnostic female-specific tools reliable? (biomarkers) Is the reproductive state important for treatment and diagnosis?

7 InterContinental Hotel, Berlin, Germany - June 18-21, : : PRESCRIBING HORMONE REPLACEMENT THERAPY (HRT) DURING MENOPAUSAL TRANSITION Re-evaluation of Women s Health Initiative (WHI) data on a subset of early menopausal women indicates that the benefits outweigh the risks! HRT has no Place in the Treatment of Depression During Perimenopause Yes: HRT has no place in the treatment of perimenopausal women No: Trial of treatment with HRT can be an important tool in overcoming perimenopausal symptoms Putting WHI results in perspective Are all HRT similar? Are estrogens alone safer and more effective? For which indication? Should we limit the treatment to early menopause? Short-term or long-term treatment? Alternatives to HRT - are they at all effective? Should psychiatrists refrain from prescribing HRT? PERINATAL PSYCHIATRIC DISORDERS The uniqueness of Perinatal Psychiatric Disorders (PPD) is being invalidated by the APA based on the diagnostic system, but continues to be endorsed by most psychiatrists in other countries Are PPD unique? Yes: No: TREATMENT CHOICES FOR PREMENSTRUAL SYNDROMES (PMS/PMDD) Despite the established efficacy of (SSRIs) and (SNRIs) in the treatment of PMDD their use is not universally accepted Should antidepressants be prescribed routinely for women with premenstrual complaints? Pros: Cons: Clinical issues in prescribing for PMS/PMDD Are hormonal therapies an option? Should the SSRIs/SNRIs be prescribed continuously, or intermittently (during the late luteal phase only)? How long does a responder need to stay on the medication? Is there any evidence that herbal/alternative treatments work? DEMENTIA The value of sub-classification and the mode of treatment of the various types of dementia (like Mild Cognitive Impairment (MIC), Alzheimer, Vascular Dementia, Lobar Dementia, Lewis Body disease (LB) dementia) are still controversial Proposition: Sub-classification of dementia has no therapeutic impact and hence is not needed Opposition: Sub-classification of dementia is important clinically and therapeutically Should demented - agitated or psychotic patients be treated with antipsychotic drugs and if so, for how long? SCHIZOPHRENIA Schizophrenia is one of the most common psychiatric diseases yet many questions are still unanswered! Are Second Generation Antipsychotics (SGA) better than First Generation Antipsychotics (FGA)? Is identification and RX treatment of pordoromal symptoms in schizophrenia possible and justified? Can cognitive impairment in schizophrenia be characterized and treated? Is administration of 2 antipsychotics ever justified?

8 8 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Sponsorship Opportunity List As outlined below, there are a number of opportunities for sponsorship available. In addition to the individual benefits of each package, all sponsors will be acknowledged on the Congress Website and in the final Congress Program. If you are interested in any of the sponsorship opportunities below, please contact the Congress Organizer Continuing Medical Education (CME) Approved Symposium 30,000 The Sponsor may provide a grant to support an existing session or suggest a CME-approved session (1.5-2 hours) as part of the Scientific Program. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Four complimentary registrations (for symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 12 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 per sq.m Two complimentary registrations for exhibitors. Additional exhibitor s registration may be purchased at 350 per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website, providing a two-way link The Sponsor's brochure will be inserted in the participants' bags Satellite Symposium (NON-CME APPROVED) 40,000 The Sponsor may organize an industrial non-cme Satellite Symposium (1.5-2 hours) as part of the Scientific Program. Organizing Committee approval of the content and speakers is required. Date and time of the Symposium will be mutually agreed upon. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Five complimentary registrations (for Symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 16 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 per sq.m Two complimentary registrations for exhibitors. Additional exhibitor s registration may be purchased at 350 per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link The Sponsor's brochure will be inserted in the participants bags

9 InterContinental Hotel, Berlin, Germany - June 18-21, PRE/POST-Congress Satellite Symposium (NON-CME APPROVED) 50,000 (This option is particularly suited for drug launching and other special events) The Sponsor may organize an industrial non-cme approved Pre/Post-Congress Satellite Symposium, for 3-4 hours (or more) on Thursday (June 18th, 2009), just before the official opening of the Congress, or at the end (June 21st, 2009) of the Congress. The expenses of the Symposium s chairpersons and speakers (registration, accommodation and travel) will be the responsibility of the Sponsor. Symposium hall and standard audio/visual equipment Six complimentary registrations (for symposium chairpersons and speakers) A 100-word sponsor/product profile will be published in the final Congress Program Approximately 20 sq.m exhibition space Additional space may be obtained at a special, reduced price of 400 per sq.m Two complimentary registrations for exhibitors. Additional exhibitor's registration may be purchased at 350 per person One A4 page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website, providing a two-way link The Sponsor's brochure will be inserted in the participants bags LUNCH (per lunch) 25,000 The Sponsor may subsidize 'in part' a buffet lunch served on Friday, (June 19th, 2009) and/or on Saturday (June 20th, 2009). Four complimentary registrations (for the Sponsor s staff) The Sponsor's logo will appear on a special board at the Lunch venue A 100-word sponsor/product profile will be published in the final Congress Program An A4 half-page advertisement, full color, published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link The Sponsor s brochure will be inserted in the participants' bags Lunch Symposium (NON-CME APPROVED) 40,000 The Sponsor may organize an industrial CME Lunch-tailored Symposium, for up to one hour as part of the Scientific Program. Please contact the Congress Organizer to coordinate the details.

10 10 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Other Sponsorship Opportunities In addition to the major sponsorship opportunities, a range of other sponsorship packages is available to meet various needs. Welcome Reception: Sole Sponsorship 20,000 A Welcome Reception for all participants will be held on Thursday evening at the Congress venue. The Sponsor s logo will appear on a special board at the Welcome Reception venue A 100-word sponsor/product profile will be published in the final Congress Program An A4 half-page advertisement, full color, published in the final Congress Program The Sponsor s logo will be published on the Congress Website, providing a two-way link The Sponsor s brochure will be inserted in the participants' bags Congress Program: Sole Sponsorship 15,000 The final Congress Program will include the Scientific Program of the Congress. The Congress Program will be distributed to all participants and will be an invaluable reference book after the Congress One A4 page advertisement, full color, published on the back cover of the final Congress Program A 100-word sponsor/product profile will be published in the final Congress Program The Sponsor's logo will be published on the Congress Website providing a two-way link Faculty Dinner: Sole Sponsorship 10,000 A Faculty Dinner will be held for the invited speakers of the Congress. The Sponsor s logo will appear on a special board at the Faculty Dinner venue The Sponsor s logo will be published on the Congress Website, providing a two-way link Internet Café: Sole Sponsorship 10,000 The Sponsor will provide workstations and technical assistance in the Internet Cafe Display Sponsor logo/information on screensaver Display Sponsor logo/information on screen background Distribute mouse pads and related promotional gifts at the cyber center The Sponsor s logo will be published on the Congress Website, providing a two-way link

11 InterContinental Hotel, Berlin, Germany - June 18-21, Participant Bags: Sole Sponsorship 10,000 The sponsor is asked to kindly provide the participants bags for the Congress themselves. The bags will be distributed to each participant of the Congress. The Sponsor's brochure/s will be inserted in the participants' bags The Sponsor's logo will be published on the Congress Website, providing a two-way link CD-ROM 10,000 The CD-ROM will contain all of the COPSy Congress abstracts and will be distributed to all the participants from the Sponsor s exhibition booth. An exchange voucher (printed by the Sponsor) will be placed in the Congress kit. Exclusive advertisement on the cover of the voucher Exclusive advertisement on the cover of the CD-ROM cover. Mini Program: Sole Sponsorship 5,000 A pocket-size Program together with their registration bags will be distributed to all participants. The Sponsor s exclusive advertisement on the back cover of the Mini Program The Sponsor's logo will be published on the Congress Website, providing a two-way link Translation from English 5,000 Simultaneous Translation from English to any required language (Cost per hall per day) The Sponsor s logo will appear on a special board in the hall The Sponsor's logo will be published on the Congress Website, providing a two-way link Congress Lanyard: Sole Sponsorship The Sponsor provides printed lanyards for the name badges 3,000 Congress provides the printed lanyards for the name badges 6,000 The Sponsor/product name, logo or text printed on lanyards The Sponsor s logo will be published on the Congress Website, providing a two-way link

12 12 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Speaker s Sponsor Speaker from Europe 2,000 Speaker from USA 6,000 The Sponsor may participate in supporting the expenses of one or more invited speakers from Europe, the USA or any other continent. Expenses include registration, accommodation and transportation. The Sponsor s logo will be published on the Congress Website, providing a two-way link Prizes for Outstanding Abstracts 3,000 Six prizes of 500 each will be presented to six of the most outstanding abstracts/posters. This will be announced before the congress, on the Website and to all the participants. The Sponsor s representative will be invited to attend the prize giving The Sponsor s logo will be published on the Congress Website, providing a two-way link Writing Pads and Pens 3,000 The Sponsor will provide the participants notepads and pens. This can be an effective high-profile sponsorship opportunity for a drug launch or for immediate brand recognition. The Sponsor s logo will be published on the Congress Website, providing a two-way link The notepads and pens will bear the sponsor's company product/logo and will be distributed in the Congress bags. Brochure Insert 3,000 Based on the specifications of the sponsor, a brochure will be inserted in the Congress bag. The bag will be distributed to all of the participants of the Congress. The Sponsor s logo will be published on the Congress Website, providing a two-way link

13 InterContinental Hotel, Berlin, Germany - June 18-21, General Information Venue Berlin, Germany Congress Organizer Congress Organizers and Secretariat ComtecMed 53 Rothschild Blvd. PO Box 68, Tel Aviv 61000, Israel Tel: Fax: copsy@comtecmed.com Liability and Insurance The organizer is not liable whatsoever for injuries or damages involving persons and/or property during the Congress. Participants are advised to issue their own personal travel and health insurance for their trip. Language The official language of the Congress is English. Sponsorship and Exhibition Contact ComtecMed c/o Lina Deshilton 53 Rothschild Boulevard, PO Box 68 Tel Aviv, 61000, Israel Tel: Fax: lina@comtecint.com Website: A professional exhibition will be held at the InterContinental Berlin in conjunction with the Congress. The floor plan has been designed so as to maximize the exhibitors exposure to the delegates. Coffee breaks will be held in this exhibition area. Exhibition spaces will be released for general sale six months prior to the opening date of the Congress. Prior to this date, sponsors will have exclusive rights for space selection. Registration Participants Physicians & scientists Early Registration Until January 1st, 2009 Late Registration After January 1st, 2009 On Site Residents* Accompanying Persons 140 *Refers to non-tenured junior scientists. Registration form must be accompanied by documentation of residency or a letter from the head of department confirming their status. The letter should be on the department letterhead and addressed to the Registration Department of the Congress. Registration includes: Participation in scientific sessions, Congress bag, Program and Abstract Book, all printed material of the Congress, invitation to the Get-Together Reception, coffee breaks, lunch on Friday and Saturday. Special Group Registration Policy is available upon request. Introduction We have managed to book the best available allocation in major hotels in Berlin that will enable us to comply with all of your future accommodation requests. We have negotiated the best available special group rates for the companies. If your company is interested in booking hotel accommodation ComtecMed will be pleased to negotiate the rates and allocation for you. Communication Please correspond directly with ComtecMed for any of your requirements i.e., accommodation, registration, social events, transfers, manpower or any other relevant service that you may require for your group. ComtecMed will negotiate the best available rates for you and confirm these services. We strongly recommend you to book accommodation as soon as possible. Payment and Cancellation Policy ComtecMed has negotiated well in advance the best possible conditions regarding cancellation and re-funding, which will be sent to you upon requesting room allocation. Accommodation and Registration ComtecMed 53 Rothschild Boulevard, PO Box 68 Tel Aviv, 61000, Israel Tel: Fax: copsy@comtecmed.com

14 14 InterContinental Hotel, Berlin, Germany - June 18-21, 2009 Exhibition Congress Hours Set-Up Time Wednesday, June 17th, :00-22:00 Thursday, June 18th, :00-17:00 Opening Hours Friday, June 19th, :00-17:30 Saturday, June 20th, :00-17:30 Sunday, June 21st, :00-13:00 Dismantling Hours Sunday, June 21st, :00-17:30 Non-Sponsor Booths Non-Sponsor companies may obtain a space/booth at the exhibition at 800 per sq.m. and the minimum booth size is 5x3 sq.m. Exhibitor name, details and a 100-word company/product profile will be published in the Congress Program Exhibitor Registration All exhibitors are required to be registered and will receive a nametag displaying the exhibiting company s name; Exhibitors will receive two nametags as part of their exhibit package; Additional exhibitor nametags may be purchased at 800 each. Site Inspection Sponsors and exhibitors are welcome to visit the Congress venue. For further information, please contact our office at: lina@comtecmed.com A 100-word Exhibitor Company/Product profile will be published in the list of exhibitors in the official program and must be submitted electronically by to: copsy@ comtecmed.com Liability and Insurance The organizer carries no liability whatsoever for injuries or damages involving persons and/or property during the Congress. Participants are advised to issue their own personal travel and health insurance for their trip. Application for Sponsorship Written application for Sponsorship should be made on the enclosed Application Form. Once an application is made, a contract will be forwarded for completion. This contract should be signed and returned with a 50% deposit, payable to Comtec. Alternatively, an invoice for the deposit may be requested on the Application Form. Once the deposit has been received, confirmation of sponsorship will be provided with an appropriate invoice. Payment Information On receipt of your application, a contract will be sent to you for completion. The contract should be signed and returned to the sponsorship/exhibition office at the address above, including a 50% deposit payment. An invoice for the deposit will be supplied upon request. As soon as we receive the form, we will mail you a confirmation of sponsorship and an invoice. Terms of Payment 50% will be deposited along with the signed contract; Balance due will be paid 3 months before the Congress opens. Payment Please make your payment by bank transfer to: Comtec Ltd. Bank Hapoalim Branch Number: 656 Account Number: SWIFT Code: POALILIT IBAN: IL Cancellation Policy Cancellation must be made in writing to Comtec; The organizers will retain: 10% of the agreed amount if the cancellation is made more than 6 months prior to the Congress. 50% of the agreed amount if the cancellation is made 4 months prior to the Congress. There will be no refund if cancellation is made 4 months or less before the opening of the Congress.

15 InterContinental Hotel, Berlin, Germany - June 18-21, Sponsorship Booking Form ComtecMed Medical Congresses Fax: Rothschild Boulevard Tel: P.O. Box 58 lina@comtecint.com Tel Aviv 61000, Israel Website: Contact Name Name of Company Address Post/Zip Code Telephone Country Fax Website I would like to book the following Sponsorship items: Sponsorship item Pre-Congress Satellite Symposium Package 50,000 Lunch Symposium 40,000 Satellite Symposium Package 40,000 CME-Approved Symposium Package 30,000 Lunch 25,000 Welcome Reception 20,000 Congress Program Book 15,000 CD-ROM 10,000 Faculty Dinner 10,000 Internet Café 10,000 Participants Bags 10,000 Congress Lanyards 6,000 or 3,000 Speaker s Expenses from United States 6,000 Mini/Pocket Program 5,000 Translation from English 5,000 Writing Pads and Pens 5,000 Brochure Insert 3,000 Prizes for Outstanding Abstracts 3,000 Speaker s Expenses from Europe 2,000 I would like to book Exhibition space: Sponsor Booth at 400 per sq.m (Minimum Booth Size: 5x3 sq.m) Non-Sponsor Booth at 800 per sq.m (Minimum Booth Size: 5x3 sq.m) Please call me to discuss the sponsorship package Please send me a sponsorship contract and first 50% deposit invoice. Price Signature Date

16 Berlin