Inaugural Meeting of the European ALCL Study Group

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Inaugural Meeting of the European ALCL Study Group June 11 th 12 th 2010 Salzburg, Austria Laboratory for Immunological and Molecular Cancer Research IIIrd

1 Inaugural Meeting of the European ALCL Study Group June 11 th 12 th 2010 Salzburg, Austria Laboratory for Immunological and Molecular Cancer Research IIIrd Medical Department with Hematology, Medical Oncology, Hemostaseology, Rheumatology and Infectiology of the Paracelsus Medical University Salzburg Prof. Richard Greil

2 SCIENTIFIC PROGRAM FRIDAY, JUNE 11 TH 2:00 Arrival and coffee 2:30 Introductory remarks Plenary Talk 3:00 Giorgio Inghirami - overview Session 1 origins of the t(2;5) and early events in oncogenesis 3:45 Stephan Mathas ALCL depends on NPM-ALK or not? 4:10 Suzanne Turner NPM-ALK induced senescence: The role of p53 4:35 Emanuela Colombo NPM-ALK induced senescence: The role of p16 5:00 Closing remarks with coffee 5:30 Finish 6:45 Reception in at the Bibliotheksaula 7:00 Concert in the Bibliotheksaula 8:00 Dinner SATURDAY, JUNE 12 TH 9:00 Opening comments Session 2 Mouse models of ALK-induced malignancies 9:05 Sylivie Giuriato Development of a conditional model for ALK-induced lymphomagenesis 9:30 Suzanne Turner NPM haploinsufficiency does not contribute to t(2;5) induced lymphomagenesis 9:55 Justus Duyster The significance of BCL-3 expression for the pathogenesis of ALK positive ALCL 10:20 coffee

3 Session 3 ALCL potential targets for therapeutic intervention 10:40 Olaf Merkel NPM-ALK and mirnas 11:05 Lukas Kenner NPM-ALK and JNK 11:30 Roberto Chiarle - New insights on the role of morphology, phenotype and angiogenesis in ALK-mediated cell transformation 11:55 Karen Pulford immune response to ALK 12:20 Round table discussion over lunch Funding opportunities European framework/marie Curie/European Science Foundation Exchange Programs Collaborations Material sharing/repository Where should future research be directed How often should we meet/ next venue/host Website Afternoon Evening Sight seeing Meeting in the garden of the Augustine monastery who have a famous brewery

4 Participant Contact Details Richard Greil Salzburg Olaf Merkel Salzburg Frank Hamacher Salzburg Lukas Kenner Wien Suzanne Turner Cambridge Karen Pulford Oxford Georgio Inghirami Torino Pier Giuseppe Pelicci Milano Roberto Chiarle Torino Bernd Dorken Berlin Stephan Mathas Berlin Justus Duyster München Sylvie Giuriato Toulouse Fabienne Megetto Toulouse Estelle Espinos Toulouse Emanuela Colombo Milano Christiane Thallinger Wien Organizing committee: Suzanne Turner, Cambridge; Lukas Kenner, Vienna; Olaf Merkel, Salzburg

5 Very close to the hospital there are no hotels. We can suggest a hotel, Lasserhof, where probably most of the people will live, please state you are from the ALCL meeting, 12 rooms have been reserved, TV and wlan/internet in all rooms, and it is still in walking distance: Hotel Lasserhof Lasserstrasse 48 Tel: hotellasserhof@magnet.at Rooms around 75 Euro 20 min (nice) walk to the Hospital 12 rooms for ALCL meeting, This is a second option, a small hotel in an old beautiful villa: Hotel Villa Carlton Markus Sittikus Str. 3 Tel: hotel@villa-carlton.at Rooms starting at 90 Euro 15 min (nice) walk to the Hospital (same track as above) 3 double rooms 90 Euro 1 suite (120 Euro) reserved for ALCL

6 Train Station LIMCR_ALCL meeting, SALK Müllner Hauptstrasse 48 Hotel Villa Carlton Markus Sittikus Str. 3 Hotel Lasserhof Lasserstrasse 48

7 How to find the site of the ALCL meeting (LIMCR) inside Salzburger Landeskliniken (SALK)? The meeting will take place in the Seminarraum of the 3 rd Medical Department, which is just beneath the Laboratory for Immunological and Molecular Cancer Research at the Campus of the Salzburger Landeskliniken, Müllner Hauptstr. 48,. In case of immediate questions the following telephone numbers are recommended: , Olaf Merkel , Frank Hamacher , Eveline Sifft LIMCR LI

September 27 th 28 th, 2016 Vienna, Austria. The Twin House 19, Hasenauer Strasse 61 (Sept. 27 th ) Billroth House 9, Frankgasse 8 (Sept.

7 th Meeting of the September 27 th 28 th, 2016 Vienna, Austria The Twin House 19, Hasenauer Strasse 61 (Sept. 27 th ) Billroth House 9, Frankgasse 8 (Sept. 28 th ) The ERIA meeting takes place under the