Target audience. Accreditation

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3 Aim of the course Fertility preservation is one of the most important challenges for physicians working in the field of human reproduction. Nowadays, the procedures aimed at preserving and restoring fertility in women should not be limited to patients undergoing oncological therapy but should also be available in other clinical conditions in which the reproductive function can be impaired, such as endometriosis, premature ovarian failure and ovarian ageing. Endometriosis, which affects 14 million reproductive-aged women in Europe and 150 million in the world, is one of the leading causes of infertility and it is estimated that 30-40% of women affected by endometriosis is infertile. Nevertheless, the mean time to diagnosis for this pathology is nine years. Indeed, a correct multidisciplinary approach is absolutely mandatory to diagnose endometriosis earlier and to better treat the affected women. This symposium aims to provide a broad and up-to-dated review of endometriosis (genetics, pathogenesis, treatment, reproductive outcomes) and an examination of the techniques for oocyte and ovarian tissue cryopreservation that are clinically available as well as those that are still in the experimental phase. To achieve this objective, the meeting has a distinguished panel of speakers who have dedicated their professional life and scientific activity to endometriosis and the preservation of female fertility. In particular, the symposium is a tribute to Prof. J. Donnez, one of the pioneers of female fertility preservation, whose experience and knowledge represent a precious gift for all physicians working in reproductive medicine. Learning objectives After attending the meeting, the participants will be able to: Apply the principles of early diagnosis and treatment of endometriosis in clinical practice Describe the most recent clinical procedures for oocyte and ovarian tissue cryopreservation Recognize the challenging future objectives for the experimental research Target audience Gynecologists with specific surgery skills, reproductive clinicians and biologists who work in the field of endometriosis and oocyte and ovarian tissue cryopreservation. Accreditation An application will be made to the EACCME for CME accreditation of the Serono Symposia International Foundation Fertility preservation: from endometriosis to ovarian tissue cryopreservation September 2012, Brussels, Belgium. 1

4 Learning effectiveness project The world of CME is changing with many different live and online formats, and Serono Symposia International Foundation (SSIF) is continually trying to develop its CME activities. With your participation in a structured series of evaluations, SSIF can provide cutting-edge learning activities designed to give you the greatest value from the time you invest. SSIF will be running the learning effectiveness project for this meeting. You will be involved in four main steps that will be explained in detail once you register. Find out more here Scientific organizer Marie-Madeleine Dolmans Université Catholique de Louvain Brussels, Belgium Scientific secretariat Serono Symposia International Foundation Salita di San Nicola da Tolentino, 1/b Rome, Italy Project Manager: Chloé Xilinas Tel.: Fax: info@seronosymposia.org Serono Symposia International Foundation is a Swiss Foundation with headquarters in 14, rue du Rhône, 1204 Geneva, Switzerland Organizing secretariat Meridiano Congress International Via Sapri, Rome - Italy Congress Coordinator: Titty Alvino Phone: Fax: c.alvino@meridiano.it 2

5 All Serono Symposia International Foundation programs are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. This program is made possible thanks to educational grants received from Arseus Medical, Ferring NV, GlaxoSmithKline Pharmaceuticals, Johnson & Johnson Medical NV/SA, KARL STORZ GmbH & Co. KG, Lumenis Ltd., Merck Serono Belgium, PregLem S.A., Richard Wolf Endoscopie, Stöpler Belgium nv/sa, Teva Pharma Belgium NV, Toshiba Medical Systems Belgium, Université catholique de Louvain (UCL) 3

6 Call for abstract Authors are requested to send their abstract by by August 20, 2012 to the following address: All applicants must register to the meeting to be able to participate to the call for abstract. Topic choice Endometriosis Ovarian tissue cryopreservation Submission procedure Abstracts must be written in English. Abstracts should be 1 page in length and include the title of the presentation, the author s names, the name of the institution, the city and country. The abstract should be structured with an : Introduction : informative and short; Material and Methods : indicating the location, number and type of human subjects, non-human species or material being studied, the principal procedures, assays, tests or treatments performed; Results : confirming or refuting the hypothesis, supported by statistics if appropriate; Conclusions : stating the major new findings of the study and specifying what these findings add to what is known already. Abbreviations: can be used after defining them first. The use of graphs, tables and images is strongly discouraged. Abstract title: do not use capital letters and do not indent. The title should reflect the contents and should be no longer than 150 characters. Authors: list the authors with initials first, followed by family name (i.e. B. Jones; J. Smith; and A. Simpson). Include the affiliation. Do not include professional titles or degrees. Font: use font Times New Roman, size 12, and line spacing 1.5. Prize The best abstract for each topic (endometriosis and ovarian tissue cryopreservation) will be honored by Prof. Donnez during the meeting and will receive a price of 2000,00. The Scientific Committee will review the submitted abstracts and choose up to 10 best abstracts (5 in endometriosis and 5 in ovarian tissue cryopreservation) for a poster session at the meeting. 4

7 List of faculty members

8 David Albertini Kansas University Medical Center Kansas City, KS, USA Christiani Amorim Université Catholique de Louvain Brussels, Belgium Claus Yding Andersen The Fertility Clinic Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark David Barlow The University of Glasgow Glasgow, UK Pedro Barri Institut Universitari Dexeus Barcelona, Spain Philippe Bouchard Université Pierre et Marie Curie Paris Paris, France Ivo Brosens Leuven Institute for Fertility and Embryology Leuven, Belgium Sylvie Defrère Université Catholique de Louvain Brussels, Belgium Marie-Madeleine Dolmans Université Catholique de Louvain Brussels, Belgium Jacques Donnez Université Catholique de Louvain Brussels, Belgium Jean-Bernard Dubuisson Hôpital Fribourgeois Fribourg, Switzerland Bart Fauser University Medical Center Utrecht, the Netherlands 6

9 Reinaldo Gonzalez-Ramos University of Chile Santiago, Chile Stephan Gordts Leuven Institute for Fertility and Embryology Leuven, Belgium Outi Hovatta Karolinska University Hospital Huddinge Stockholm, Sweden Pascale Jadoul Université Catholique de Louvain Brussels, Belgium Ludwig Kiesel Department of Gynecology and Obstetrics University of Münster Münster, Germany S. Samuel Kim University of Kansas Kansas City, KS, USA Philippe Koninckx Katholieke Universiteit Leuven Leuven, Belgium Ernest Loumaye Preglem Geneva, Switzerland Dror Meirow Sheba Medical Center, Tel-Aviv University Tel-Aviv, Israel Pasquale Patrizio Yale University New Haven, CT, USA Antonio Pellicer Infertility Institute of Valencia (IVI) Valencia, Spain Céline Pirard Université Catholique de Louvain Brussels, Belgium 7

10 Bruno Salle Hôpital Femme Mère Enfants, Université Claude Bernard Lyon, France Sherman Silber Infertility Center of St. Louis, St. Luke's Hospital St. Louis, MO, USA Johan Smitz Center for Reproductive Medicine, Vrije Universiteit Brussel Brussels, Belgium Jean Squifflet Université Catholique de Louvain Brussels, Belgium Nao Suzuki St. Marianna University School Medicine Kanagawa, Japan Evelyn Telfer University of Edinburgh Edinburgh, UK Anne Van Langendonckt Université Catholique de Louvain Brussels, Belgium Ana Veiga Institut Universitari Dexeus Barcelona, Spain Hamish Wallace Royal Hospital for Sick Children, University of Edinburgh Edinburgh, UK Mary Zelinski Oregon National Primate Research Center, Oregon Health and Sciences University Corvallis, OR, USA 8

11 Scientific program

12 Scientific program Thursday, September Registration SSIF welcome R. Fischer, Germany Scientific organizer welcome M.-M. Dolmans, Belgium Session I Endometriosis - research Chairmen: E. Loumaye, Switzerland; S. Gordts, Belgium Endometriosis and inflammation R. Gonzalez-Ramos, Chile Endometriosis and genetics D. Barlow, UK Medical therapy in endometriosis: from the past to the future P. Bouchard, France Endometriosis and the great obstetrical syndromes I. Brosens, Belgium Coffee break Session II Endometriosis clinics Chairmen: J.-B. Dubuisson, Switzerland; J. Squifflet, Belgium Recent advances in diagnostic biomarkers for endometriosis, including the nerves L. Kiesel, Germany Surgery for endometriomas: when and how? S. Gordts, Belgium The endometriosis surgery challenge: shaving versus rectal resection in deep endometriosis P. Koninckx, Belgium Conclusions and take home messages J.-B. Dubuisson; S. Gordts; E. Loumaye; J. Squifflet Lunch 10

13 Session III Ovarian tissue cryopreservation research: the oocyte Chairmen: O. Hovatta, Sweden; J. Smitz, Belgium; C. Pirard, Belgium The follicle point of view: from tissue to Petri dish E. Telfer, UK The host point of view: from thawing to grafting M. Zelinski, USA The researcher point of view: evaluating follicle quality and chances to pregnancy D. Albertini, USA Coffee break In vivo post-grafting recovery of folliculogenesis and ovulation: the role of pressure S. Silber, USA Gametes from pluripotent stem cells A. Veiga, Spain Freeze/drying oocytes (lyophilization) and stem cells as the new frontiers in cryopreservation P. Patrizio, USA Conclusions and take home messages O. Hovatta; J. Smitz; C. Pirard End of the first day 11

14 Scientific program Friday, September Session IV Ovarian tissue cryopreservation clinics Chairmen: P. Barri, Spain; P. Jadoul, Belgium; S.S. Kim, USA Poster awards: Jury: C. Amorim, Belgium, S. Defrère, Belgium 1 selected oral communication on ovarian tissue cryopreservation 1 selected oral communication on endometriosis Premature menopause: how to define it? B. Fauser, The Netherlands Iatrogenic premature menopause and fertility preservation H. Wallace, United Kingdom Can we protect the primordial follicle before aggression? D. Meirow, Israel : Fertility matters: from endometriosis to ovarian tissue cryopreservation: 25 years of research J. Donnez s Gyne Research Laboratory Coordinators: A. Van Langendonckt, M.-M. Dolmans, Belgium Conclusions and take home messages P. Barri; P. Jadoul; S. S. Kim Coffee break 12

15 Session V Ovarian tissue transplantation - clinics Chairmen: H. Wallace, UK; B. Fauser, the Netherlands Ovarian tissue transplantation: myth or reality? C. Y. Andersen, Denmark Ovarian tissue transplantation: the Belgian experience M.-M. Dolmans, Belgium Ovarian tissue vitrification: the option of the future? N. Suzuki, Japan Is the whole ovary transplantation (fresh or frozen) still indicated? B. Salle, France Final lecture: Oocyte vitrification and social freezing: fertility preservation of the future? A. Pellicer, Spain Take home messages H. Wallace, B. Fauser Conclusion M.-M. Dolmans, Belgium 13

16 General information Venue The Hotel The Hotel, Brussels Boulevard de Waterloo 38, 1000 BRUSSELS Language The official language of this course will be English Registration fee The registration fee is 250,00 This fee includes: Scientific sessions Conference coffee breaks, luncheon Conference material Certificate of attendance The Congress Dinner is not included in the registration fee and it will not be organized. follow us on Personal data treatment - Informative document In compliance with the article 13 of Italian Legislative Decree n. 196, 30 June 2003, we inform you that your personal data will be processed, with or without the use of electronic or automated means, via suitable tools that will guarantee security and confidentiality. Personal data from you supplied will be communicated to Continuing Medical Education Accreditation Authorities, to agencies that will take care of the whole accreditation process and agencies that will take care of the logistics of the event; should we not receive the below requested data, we will not be able to process your registration to the event. At anytime you may exercise your rights as laid down in the art. 7 of Italian Legislative Decree n. 196, 30 June 2003 of the Italian Law, by contacting the Data Controller Serono Symposia International Foundation (Salita di San Nicola da Tolentino, 1/b Rome - Italy) in the person of Data Processor, Michèle Piraux. 14

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18 Brussels

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20 " Registration form Serono Symposia International Foundation Fertility preservation from endometriosis to ovarian tissue cryopreservation Brussels, Belgium - September 20-21, 2012 Last Name First Name Academic Title Institution Department Address City Province/Country Postal Code Office Telephone Number(s) Fax Number Mobile Telephone Number(s) Registration Fee The registration fee is 250,00 Once registrations are confirmed, full penalty applies for cancellations. I require special assistance (wheelchair, auxiliary aids) or special dietary requirements. Payment q Payment by Bank Transfer headed to: Meridiano viaggi e turismo S.p.A" BANCA INTERMOBILIARE S.p.A FILIALE DI ROMA - VIA DONIZETTI, ROME - ITALY Account number: IBAN: IT55 F SWIFT: BIMTITTTXXX q Payment by Credit Card Charge to the following Credit Card (Credit Card commission Fee 3,5%): m MasterCard/EuroCard m Visa Card Number Exp. Date Card Holder Name (PLEASE PRINT) Card Holder s Signature Date ONLY REGISTRATION FORMS ACCOMPANIED WITH PAYMENT CAN BE PROCESSED Mail to: Titty Alvino c/o Meridiano Congress International Via Sapri, Rome, Italy T F c.alvino@meridiano.it All completed registration forms will be acknowledged by or fax.

21 Mail to: Meridiano Congress International Att. Titty Alvino Via Sapri, Rome Italy

22 Hotel accommodation form Serono Symposia International Foundation Fertility preservation from endometriosis to ovarian tissue cryopreservation Brussels, Belgium - September 20-21, 2012 Last Name First Name Academic Title Institution Department Address City Province/Country Postal Code Office Telephone Number(s) Mobile Telephone Number(s) Fax Number For hotel reservation, please return the completed form with full prepayment of the requested nights. Hotel Reservation forms without prepayment cannot be processed. Accommodation will be subject to availability and requests will be processed on "first-come first-served" basis. q THE HOTEL BOULEVARD DE WATERLOO 38, 1000 BRUSSELS, BELGIUM Double room for single use: 175,00 per night Check in date: Check out date: (N of nights: ) Rates include breakfast and city taxes. Payment q Payment by Bank Transfer headed to: Meridiano viaggi e turismo S.p.A" BANCA INTERMOBILIARE S.p.A FILIALE DI ROMA - VIA DONIZETTI, ROME - ITALY Account number: IBAN: IT55 F SWIFT: BIMTITTTXXX q Payment by Credit Card Charge to the following Credit Card (Credit Card commission Fee 3,5%): m MasterCard/EuroCard m Visa Card Number Exp. Date " Card Holder Name (PLEASE PRINT) Card Holder s Signature Date Mail to: Titty Alvino c/o Meridiano Congress International Via Sapri, Rome, Italy T F c.alvino@meridiano.it Once you confirm rooms to Meridiano, full penalty will be applied in case of cancellation.

23 Mail to: Meridiano Congress International Att. Titty Alvino Via Sapri, Rome Italy

24 Improving the patient s life through medical education T F

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