Postnatal the second window of opportunity. S. Paredes

Transcription

1 Postnatal the second window of opportunity S. Paredes 30 March 2015

2 Outline 1 Introduction 4 Trans-generational effects 2 Birth weight the limiting factor? 5 Benefits of investing in early life 3 Alternatives during the 2 nd window of opportunity 6 Take home message 2

3 LifeStart. Welfare Economic implications

4 Birth weight - the limiting factor?? 4

5 BW, kg Birth weight is NOT always the limiting factor * * * * * 5 * 0 SRC,

6 Animals, % Birth weight is NOT always the limiting factor Permanent effect? remain increase decrease Problem is not efficiencyrelated < -3.0 to to to to to to to average 6 Nutreco R&D, 2012

7 Nursery exit weight is determined: 30% by birth weight 30% by weaning weight 70% by weight during the first weeks after weaning Paredes et al., 2012

8 Market BW, kg Relation to market weight Measured Calculated BiW < 20% WeaW 20% 10 wk weight 35% Finishing period < 20% 78% accuracy to determine slaughter weight Paredes, unpublished 8

9 Light weight piglets are NOT that different Paredes et al.,

10 Light weight piglets are NOT that different 10 Paredes et al., 2014

11 They suffered from an earlier stressor 11 Paredes et al., 2013

12 for which they can compensate Move to average performance group 12 Nutreco R&D, 2013

13 Within a time frame 13

14 Alternatives from 14 to 42 days of age Early feed intake = Faster adaptation to challenges 15

15 LifeStart key pilars Pig GIT Other factors Management Genetics Gut microbiota Processes in gut wall Digestion & absorption Health and growth Immune competence Adequate immune response Over/Under immune response Reduced health and Health and growth 17 growth

16 Different genetics = different needs 18 Nutreco R&D

17 One diet DOES NOT fit all 19 Agresearch, 2013

18 Creep feed Healthier colon, lower signs of inflammation Also Lowest removals Less ß-haemolytic bacteria Enhances the resilience to weaning Creep (day 19-27) Progeny of multiparous sows Adapted from Edwards,

19 Early post-weaning intake is stimulated by diet composition Day 0 14 post-weaning: 30 g/d extra feed intake 30 g/day extra growth 6.5% less diarrhoea 22 Nutreco R&D, 2013

20 Complex diet = Higher % piglets eating Wellock,

21 Complex diet increases microbial richness in colon 24 Paredes et al. (in preparation)

22 Average score Complex diets = lower PWD 2 1,8 1,6 1,4 1,2 1 0,8 0,6 0,4 0,2 0 * Day post weaning E. Coli infection tests at SRC HR Simple diet diet MW Complex diet diet 26 Nutreco R&D, 2012

23 ADG, g/d BW, kg FCR Complex diet help in a Strep suis challenge 120 2, ,00 1,50 1,00 0,50 0 Nursery phase Finishing period 0,00 Nursery phase Finishing period Nursery phase Finishing period 27 De Lange, 2015

24 Complex diet provide increase disease resistance Gene Gene Name Fold change P value ARG1 Arginase CPS1 Carbamoyl phosphate synthase SLA-DMA, B Swine leukocyte antigen DMA 0.55 <0.078 SLA-DQA, B1 Swine leukocyte antigen DMA 0.51 <0.057 SLA-DRA, B1 Swine leukocyte antigen DMA 0.56 <0.070 GPX1 Glutathione peroxidase 1 (cellular) GPX3 Glutathione peroxidase 3 (plasma) NR3C1 Glucocorticoid receptor TXNIP Thioredoxin interacting protein Rudar et al., 2012

25 Complex diet Higher costs P<0.05 MOF, $/pig Complex feeding program: vs. Simple feeding program: P< Van der Douglas et al., 2014

26 Muscle growth rather than fat deposition 30 Yin et al., 2010, 2013

27 Welfare implications Reduction in nr of light weight piglets Reduction in mortality More prepared piglets for the nursery challenges 31 Adapted from Edwards, 2010

28 days to market Early investment = lower days to market LifeStart Common practice 32 TN Benelux, 2014

29 Trans-generational effect 33

30 F 0 Control or experimental diet F 1 Control diet F 2 Control diet Higher shoulder % Leaner carcasses 34 Braunschweig et al., 2012

31 Reduction in embryo survival d 45 gestation Decreased uterus weight and size 0-13 d post-natal EV or control 35 Tarleton et al., 2002

32 Benefits of investing in early life 36

33 Earlier feed intake PW Microbial host relation Better immune response Higher within-batch homogeneity Lower mortality Protein accretion 4 days less to market Higher ROI 37

34 Take home message 38

35 Take home message 1. A light piglet at birth is not deemed to be the lightest 2. The first weeks post-weaning are more important than birth weight determining the fate of a piglet 3. Light weight piglets will benefit the most of complex feeding scheme 4. Complex feeding higher costs - Complex feeding = MOF 5. Targeted nutrition rather than a simple feeding will determine future performance 6. Not only economical but welfare benefits of investing in early life 7. Investing in the first 6 weeks of a pig s life will pay off in the long term 39

36 Thank you 40