Pediatric radiology. Endre Szabó

Transcription

1 Pediatric radiology Endre Szabó

2 A child is not a small adult!

3 Water content of a baby s body is higher than that of an adult, there are more free radicals and bigger damage due to radiation! Baby s chest film means almost full body irradiation with higher genetic effect for the gonads and higher somatic effect for the eye, thyroid gland and bone marrow! There is more red marrow in a baby thus bigger danger of leukemia!

4 ALARA As Low As Resonably Achievable Our aim is to minimize risk and maximize diagnostic benefit from any imaging examination - to obtain the required diagnostic information using the minimum radiation dosage. This approach is especially valid in pediatric radiology: any radiation is harmful to the child!

5 The benefits of each examination must be carefully balanced against any potential risk!

6 Reduction of radiation dosage 1. Indication of X-ray, CT examinations must be well established. 2. Examinations based on non-ionising radiation should be used whenever possible: US, MRI

7 Reduction of radiation dosage 3. Radiation protection: gonads must be shielded

8 Reduction of radiation dosage 4. Immobilisation: proper immobilisation techniques improve image quality, decrease the length of the examination, and decrease the need for repeat studies.

9 Intrauterine circulation

10 Intrauterin keringés

11 Neonatal Chest Diffuse Pulmonary Disease Causing Respiratory Distress Respiratory distress in the newborn is most commonly related to diffuse pulmonary disease 1. Small babies with decreased lung volumes on chest X-ray film granular opacities Surfactant deficient disease Beta-hemolytic Streptococcal pneumonia 2. Large babies with increased lung volumes streaky perihilar opacities on the X-ray film -Meconium aspiration syndrome -Other neonatal pneumonias -Transient tachypnoe of the newborn

12 Diffuse Pulmonary Disease Causing Respiratory Distress Small babies with decreased lung volumes - RDS Surfactant deficient disease / RDS / Hyalin membrane disease Pathology: disease of premature infants less than 36 weeks- due to deficiency of surfactant of the lungs - the alveoli collapse and prevent gas exchange Radiography: Low lung volumes secondary to microcollapse Diffuse granular opacities represent collapsed alveoli interspersed with open alveoli. Air bronchograms demonstrate patent bronchi in abnormal lung

13 Diffuse Pulmonary Disease Causing Respiratory Distress Large babies with increased lung volumes streaky perihilar opacities on the X-ray film Meconium aspiration syndrome Postmature infants and infants with inrauterine stress Intrapartum or intrauterine aspiration of meconium Meconium is the tenacious, thick viscous material in the neonatal bowel When the fetus is hypoxic, there is passage of meconium into the amniotic fluid which can enter to the lung Aspirated meconium has three effects: Airway obstruction due to tenacious meconium Surfactant dysfunction Chemical pneumonitis

14 Meconium aspiration sy. Rad. signs: High lung volumes diaphragm is lower than normal due to airways obstruction Areas of asymmetric patchy hyperinflation and atelectasis extensive patchy reticulo-granular shadowing throughout both lung fields Rope-like perihilar densities aspirated meconium in the airways Complication: Difficulty ventilating with air block Severe pulmonary hypertension Anoxic brain injury Chronic lung disease Therapy: mechanical ventillation Conventional or high frequency ventilation

15 Complications of the mechanical ventillation Arises from barotrauma and high oxygen pressures Barotrauma results in increased alveolar pressure and alveolar rupture Air leak Pulmonary interstitial emphysema (PIE) Pneumothorax, pneumomediastinum, pneumopericardium, pneumoperitoneum Pulmonary hemorrhage Bronchopulmonary dysplasia

16 Air leak - Pulmonary interstitial emphysema Radiographic signs: multiple small radiolucencies scattered throughout the affected lung- gas bubbles in the parenchyma increased volume of affected lung mediastinal shift towards the contralateral side

17 Pneumothorax - Pneumomediastinum - Pneumopericardium Clinical sign: sudden deterioration in the clinical state of the baby and increased respiratory distress Radiographic sign: detection of the lung edge and contralateral mediastinal shift Pneumothorax Pneumopericardium Pneumomediastinum

18 Bronchopulmonary dysplasia Chronic lung disease of infancy Path.: fibrotic process in the lung interstitial tissues due to barotrauma and high oxygen pressure Rad. signs: heterogeneous appearance with focal lucencies separated by coarse reticular and band-like opacities of fibrosis More opacities in the upper lobes with hyperinflation at the bases The surviving infants may subsequently develop normal radiographs in childhood!

19 Congenital heart disease Imaging modalities: 1. Echocardiography: prenatal!

20 Congenital heart disease Imaging modalities: MRI Angiocardiography Radiography: A major role of chest radiograph is access pulmonary vascularity.

21 Increased pulmonary blood flow Left to right shunt ASD VSD Persisting truncus arteriosus Transposition of great vessels

22 Decreased pulmonary blood flow Tetralogy of Fallot Pulmonary stenosis Pulmonary atresia Tricuspidal atresia Ebstein anomaly

23 Decreased pulmonary blood flow Tetralogy of Fallot Radiographic signs: oligaemia of the lungs boot-shaped heart elevated cardiac apex (PS, VSD, dextroposition of the Ao, RV hypertrophy)

24 Esophageal atresia Esophagotracheal fistula Path: esophagus ends as a blind pouch abnormal connection between tracheal and esophageal lumen Clinical signs: aspiration into the lungs

25 Esophageal atresia Esophagotracheal fistula air in the bowel if a fistula is present soft tube into the esophagus and the tube curves in the blindly ending pouch

26 Esophageal atresia without tracheoesophageal fistula air-less scaphoid abdomen

27 Congenital and developmental anomalies of the small bowel May be associated with olygohydramnion Frequently present postnatally in the first 24 hours Clinical evidence of obstruction: bilious vomiting and abdominal distension Common clinical signs: usually normal birth weight neonate after birth abdominal distension and vomiting failure to pass meconium rectal digital examination: tiny rectum

28 Obstruction of the small bowel Dg: abdominal-plain film distal extent of bowel gas help to determine the level of any obstruction -proximal: duodenal obstruction -distal: aganglionosis -intermediate: ileal or jejunal obstruction

29 Proximal obstruction: Duodenal atresia and stenosis Path: failure of recanalisation of the fetal gut, typically near the ampulla of Vater Clin signs: bilious vomiting within the first 24 hr Diagnosis: plain radiographdilatation of the stomach and duodenum, double-bubble sign, gasless abdomen below Therapy: surgery

30 Clinical signs: Intermediate obstruction: abdominal distension Bile emesis 1.Jejunoileal atresia 2.Meconium ileus Rectal digital examination: tiny rectum Meconium ileus Manifestation of cystic fibrosis - inspissation of abnormaly thick and tenacious meconium in distal small bowel Jejunoileal atresia in utero vascular accident, failure of recanalisation Intrauterine: malrotation, volvulus, herniation, intussusception Postnatally: gangrene, perforation, peritonitis

31 Jejunoileal atresia and meconium ileus Diagnosis: 1. plain radiograph of abdomen distended loops of gas-filled small bowel bubbly pattern of bowel gas: gas and inspissated meconium 2. Contrast enema may be useful for separating meconium ileus, ileal atresia and other causes of obstruction

32 Distal obstruction Congenital aganglionosis - Hirschsprung s disease Pathology: Absence of both myenteric and submucosal plexus Usually in the sigmoid or rectosigmoid region Clinical signs: Distension Vomiting Initial difficulty to pass meconium

33 Diagnosis: Congenital aganglionosis- Hirschsprung s disease 1. plain radiograph of abdomen distended loops with air-fluid level 2. Contrast enema Normal (or small) caliber rectum Transition zone abnormaly small distal to dilated proximal colon Dilated proximal sigmoid and remainder of the colon

34 Intussusception Path: invagination of one segment of the bowel into another between ages of 6 months and 2 years more common in boys seasonal incidence: when respiratory and gastrointestinal infections occur most common type: ileum invaginating into the colon - ileo-colic Clinical signs: abdominal mass, pain, vomiting, rectal bleeding

35 Dg: sonography - target sign sonolucent outer rim surrounding a central echogenic area on cross-section Intussusception

36 Anorectal malformation / Imperforate anus / cloacal malformation Abnormal termination of the hindgut Spectrum -True imperforate anus thin membrane -Atresia of distal rectum Clin signs lack of passage of meconium absence of normal anus Relation of rectal pouch to pubococcygeal line 1.Low -usually visible perineal orifice, stenotic or membrane -no GU tract communication 2.High -GU tract communication: rectourinary-vaginal-vestibular fistula

37 Anorectal malformation - Imperforate anus Dg: sonography - meconium filled large bowel distance from the rectal blind end to the perineum can be measured Low lesion: less than 10mm High lesion: more than 10mm (pouch terminates above the base of the bladder)

38 Anorectal malformation - Imperforate anus Radiography: (Wangensteen-Rice) plain lateral radiograph with the patient in an inverted position + a lead marker is placed on the perineum Distance between the rectal pouch and perineal marker is measured Th: colostomy or perineal surgery

39 Congenital and Developmental Anomalies of the Urinary Tract Imaging modalities: 1. Sonography 2. MR-urography 2. Radionuclid imaging 3. Excretory urography 4. Voiding cystourography 5. MRI-MRA / CT-CTA

40 Congenital and Developmental Anomalies of the Urinary Tract Anomalies of number Renal agenesis Anomalies of position Dystopia/ectopia renis Anomalies of form: Ren arcuatum/ horseshoe kidney

41 Congenital and Developmental Anomalies of the Urinary Tract Anomalies of structure: Dysplasia: Aplasia Hypoplasia Cystic disease Ren polycysticum Ren multicysticum Anomalies of the renal pelvis and ureter Ren et ureter duplex Ureterocele

42 Urinary obstruction: Hydronephrosis Most common causes: 1. Ureteropelvic junction obstruction 2. Ureterovesical obstruction 3. Bladder outlet obstruction 4. Urethral obstruction The principal structural changes: dilation and elongation of the urinary channels above the level of the obstruction!

43 Ureteropelvic junction obstruction Dilated renal collecting system but no ureter 1. Intrinsic stenosis: abnormal development of the muscle fibers at the ureteropelvic junction 2. Extrinsic stenosis: band, adhesion, aberrant vessel Clinical signs: palpable mass, abdominal pain, haematuria, urinary tract infection Diagnosis: sonography - large renal pelvis and calyces, lack of visualisation of distal ureter Therapy: surgical

44 Ureteropelvic obstruction MR-urography Excretory urography: Contrast excretion into dilated collecting system Dg: marked hydronephrosis that ends abruptly at the ureteropelvic junction with normal caliber ureter downstream

45 Ureterovesical obstruction Dilated renal collecting system with ureter

46 Ureteropelvic duplication - Ureterocele Ureteropelvic duplication: presence of two separate collecting systems in one kidney Two draining ureters may join above the bladder (partial duplication) or insert into the bladder separarely (complete duplication) The ureter draining the cephalad portion of the kidney tends to insert in the bladder inferior and medial to the ureter draining the lower segment of the kidney. The upper pole tends to obstruct. The lower pole tends to have vesicoureteral reflux The upper pole ureteral orifice is ectopic in location and often associated with ureterocele

47 Ureteropelvic duplication - Ureterocele Ureterocele: Herniation into the bladder of the dilated distal end of the ureter Categorised according to their position: Intravesical Extravesical Categorised according to their insertion: Orthotopic Ectopic

48 Brain Imaging modalities: 1. Sonography 2. MRI 3. CT Sonography is extremely valuable in identifying normal and abnormal intracranial structure. The special technique is the transcranial US scanning through the anterior fontanelle.

49 Intracranial hemorrhage 1. Periventricular - intraventricular: in premature, most common and most severe 2. Subarachnoideal: in premature common, but almost always clinically benign 3. Subdural: in full-term infant, uncommon, but usually severe 4. Intracerebellar: in premature, uncommon, but usually severe

50 Periventricular-Intraventricular Hemorrage Premature infant: weigthing less than 1500g or under 32 weeks of gestation Common site: germinal matrix at the junction of the head of the caudate nucleus and choroid plexus in the floor of the lateral ventriculus Possible causes: hypoxia or ischaemia hyperperfusion or venous distension increased vascular pressure rupture of vessels of germinative matrix PVH

51 Congenital dysplasia of the hip Abnormal position of the femoral head relative to the acetabulum which results in abnormal growth of both components of the hip More common in breech babies, fetuses with oligohydramnios Much more common in girls than boys

52 Early diagnosis is important because even a short delay can lead to abnormal hip development! Diagnosis: 1. sonography visualize the cartilaginous components of the hip - position of the femoral head, depth of the acetabulum 2. radiography the angle of the acetabular roof (should be less than 30 degrees) - Shenton line

53 Sonography: coronal image of the normal hip with the transducer positioned lateral to the femur