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1 A G A S P R I N G P O S T G R A D U A T E C O U R S E MANAGING DIGESTIVE DISEASES IN THE NEXT DECADE C O N T R O V E R S I E S A N D N E W D E V E L O P M E N T S May 1 & 2, 2010 Ernest N. Morial Convention Center New Orleans, LA Held in conjunction with DDW Register on or before April 2 and save $75 on your registration fee! A PROGRAM OF THE AGA INSTITUTE

2 C O U R S E D I R E C T O R Sheila E. Crowe, MD, AGAF C O - D I R E C T O R S Jorge A. Marrero, MD, MS Bruce E. Sands, MD, AGAF C O U R S E H I G H L I G H T S Earn up to 15 AMA PRA Category 1 Credits. Relevant take-home points that you can directly apply to your practice. A mix of learning formats that provide variety, enhance your learning experience and improve retention. Direct access to an internationally renowned faculty of top experts in the field. Syllabus containing detailed summaries of all sessions that can be used a permanent reference tool after the course. Additional copies available for purchase. This course will address what s on the horizon for the diagnosis and treatment of digestive diseases and how you can incorporate these latest advances into your practice. In addition, you will obtain practical information on how to handle difficult clinical cases and challenging endoscopic situations. The course will focus on six major topics: Upper GI Disorders Functional Diseases Inflammatory Intestinal Disorders Pancreaticobiliary Diseases Liver Disease New Frontiers in Digestive Diseases Case-Based Debates Stimulate an Exchange of Ideas Hear the experts debate the most appropriate approach to case-based problems related to major GI and liver topics. Participate in the discussion by asking questions and making commentary.

3 P R O G R A M S AT U R D AY, M AY 1 8:15 8:20 a.m. Welcome from the AGA President Gail A. Hecht, MD, MS, AGAF 8:20 8:30 a.m. Introduction Sheila E. Crowe, MD, AGAF Session I: Upper GI Disorders Moderator: David A. Peura, MD, AGAF 8:30 8:50 a.m. Barrett s Esophagus Controversies in Management: Wait, Ablate, or Resect? Stuart J. Spechler, MD, AGAF 8:50 9:10 a.m. GERD New Developments in Acid Reflux John M. Inadomi, MD, AGAF 9:10 9:30 a.m. Eosinophilic Esophagitis: What Do We Know After 15 Years? Ikuo Hirano, MD 9:30 9:50 a.m. What s New in Peptic Ulcer Disease Neena S. Abraham, MD, MSCE, FACG, FASGE 9:50 10:10 a.m. Drugs and Devices: Handling Non-variceal GI Bleeding Loren A. Laine, MD, AGAF 10:10 10:15 a.m. Moderator s Summary 10:15 10:35 a.m. Refreshment Break Session II: Liver Disease Moderator: Jorge A. Marrero, MD, MS 10:40 11 a.m. Natural History and Management of NASH Arun J. Sanyal, MD, FACP 11 11:20 a.m. What s New in Hepatitis B? Norah A. Terrault, MD 11:20 11:40 a.m. Non-responder to Hepatitis C What to Do Now? Anna S.F. Lok, MD, AGAF 11:40 a.m. Noon New Developments in Liver Cancer Gregory J. Gores, MD, AGAF Noon 12:05 p.m. Moderator s Summary 12:25 1:25 p.m. Luncheon Breakout Sessions Session III: New Frontiers in Digestive Diseases Moderator: Bruce E. Sands, MD, AGAF 1:45 2:05 p.m. CRC Screening: The Next Decade Douglas K. Rex, MD 2:05 2:25 p.m. Is It Time to Learn NOTES? David W. Rattner, MD 2:25 2:45 p.m. Recurrent and Refractory C. difficile Colitis: What are the Latest Treatment Options and What Works? Christina M. Surawicz, MD 2:45 3:05 p.m. GI Docs as Obesity Specialists? Donna H. Ryan, MD 3:05 3:25 p.m. New Imaging Modalities: How Will They Help? Glenn M. Eisen, MD, MPH, AGAF 3:25 3:30 p.m. Moderator s Summary 3:30 4 p.m. Refreshment Break 4 5:30 p.m. Clinical Challenge Sessions L U N C H E O N B R E A K O U T S E S S I O N S 12:25 1:25 p.m. Choose from 18 exciting sessions! Select a different session for each day of the course. Sessions are assigned on a first-come, first-served basis. Lunch without learning option is available. (L1XX Saturday; L2XX Sunday) L101; L201 Managing Microscopic Forms of Colitis Kenneth R. McQuaid, MD, AGAF L102; L202 Fistulizing Crohn s Disease Miguel D. Regueiro, MD, AGAF L103; L203 Handling IBD in Pregnancy Sunanda V. Kane, MD, MSPH, AGAF L104; L204 Nutritional Issues in IBD Mark H. DeLegge, MD, AGAF L105; L205 Controversies in Managing Dysplasia in IBD David T. Rubin, MD, AGAF L106; L206 Management of Anorectal Diseases Robert R. Cima, MD, MA L107; L207 Liver Transplant What You Need to Know Carl L. Berg, MD L108; L208 Managing Fulminant Hepatic Failure and Drug-Induced Liver Injury Robert J. Fontana, MD L109; L209 Evaluation of the Liver Mass Hashem B. El-Serag, MD, MPH L110; L210 Dealing with Genetic Liver Diseases: Hemochromatosis and Wilson s Disease Bruce R. Bacon, MD L111; L211 Autoimmune Liver Disease Jayant A. Talwalkar, MD L112; L212 Management of Gastroparesis Michael Camilleri, MD, AGAF L113; L213 Dealing with Dysphagia Peter J. Kahrilas, MD, AGAF L114; L214 Management Dilemmas and Upper GI Disorders Colin W. Howden, MD, AGAF L115; L215 Chronic Diarrhea Christina M. Surawicz, MD L116; L216 Digestive Diseases and the Role of Probiotics and Prebiotics John K. DiBaise, MD L117; L217 Women sissuesingi PelvicFloorDisorders Cynthia M. Yoshida, MD, AGAF L118; L218 OptimizingEndoscopicProcedures:From PrepstoSedationandBeyond What sbest? Douglas K. Rex, MD L119; L219 Not attending a lunch session The Luncheon Breakout and Clinical Challenge sessions are ticketed. You must indicate your choice(s) for these sessions using the codes listed above when completing your DDW registration form in order for your registration to be processed. If you are not going to attend a Luncheon Breakout or Clinical Challenge session, be sure to check the box on the registration form indicating that you will not attend.

4 S U N D AY, M AY 2 Session IV: Inflammatory Intestinal Disorders Moderator: Bruce E. Sands, MD, AGAF 8:30 8:50 a.m. Biologics With or Without Immunomodulators: What is the Right Thing to Do? Brian G. Feagan, MD 8:50 9:10 a.m. Dealing with the Risks of IBD Therapy Corey A. Siegel, MD 9:10 9:30 a.m. Managing Non-responsive Celiac Disease Ciaran P. Kelly, MD, AGAF 9:30 9:50 a.m. Pre-operative IBD Medical Therapy What Your Surgeon Wants You to Know Robert R. Cima, MD, MA 9:50 10:10 a.m. What s on the Horizon for Treating IBD? Maria T. Abreu, MD 10:10 10:15 a.m. Moderator s Summary 10:15 10:35 a.m. Refreshment Break Session V: Pancreatobiliary Disorders Moderator: Stuart Sherman, MD 10:40 11 a.m. Dealing with Pancreatic Cysts William R. Brugge, MD, AGAF 11 11:20 a.m. New Developments in the Management of Acute Pancreatitis Peter A. Banks, MD, AGAF 11:20 11:40 a.m. Functional Biliary Diseases: From Biliary Dyskinesia to SOD Grace H. Elta, MD, AGAF 11:40 a.m. Noon EUS/ERCP/MRCP Which Test for What Disease? Gregory G. Ginsberg, MD, AGAF Noon 12:05 p.m. Moderator s Summary 12:25 1:25 p.m. Luncheon Breakout Sessions Session VI: Functional GI Diseases Moderator: Sheila E. Crowe, MD, AGAF 1:45 2:05 p.m. What Actually Helps in Managing IBS Lin Chang, MD, AGAF 2:05 2:25 p.m. When PPIs Don t Work Handling Functional Heartburn Ronnie Fass, MD 2:25 2:45 p.m. Defecation Disorders: How to Keep it In or Get it Out? Suzanne Rose, MD, MSEd, AGAF 2:45 3:05 p.m. What to do with Functional Dyspepsia Nicholas J. Talley, MD, PhD, AGAF 3:05 3:25 p.m. What s Up with Bacterial Overgrowth? IBS & Beyond William D. Chey, MD, AGAF, FACG 3:25 3:30 p.m. Moderator s Summary and Closing Remarks 3:30 4 p.m. Refreshment Break 4 5:30 p.m. Clinical Challenge Sessions C L I N I C A L C H A L L E N G E S E S S I O N S : C A S E - B A S E D D E B AT E S 4 5:30 p.m. Choose from 12 different topics! Select a different session for each day of the course. Sessions are assigned on a first-come, first-served basis. (C1XX Saturday; C2XX Sunday) C101; C201 Controversial Issues in Viral Hepatitis Norah A. Terrault, MD and Rajender Reddy, MD C102; C202 ManagingComplicatedPortalHypertension Guadalupe Garcia-Tsao, MD and Vijay H. Shah, MD C103; C203 Managing Biliary Obstruction Stuart Sherman, MD; Grace H. Elta, MD, AGAF (Sat.); and Gregory G. Ginsberg, MD, AGAF (Sun.) C104; C204 ScreeningForandWorkingUpColonCancer focusingonhereditary/geneticsyndromes Marcia R. Cruz-Correa, MD, PhD, AGAF and Xavier Llor, MD C105; C205 Diagnostic Dilemmas in Intestinal Diseases: Which Test is Best? Neena S. Abraham, MD, MSCE, FACG, FASGE and Arthur Asher Kornbluth, MD C106; C206 Complex Nutrition Cases in Gastroenterology: Team-based Management Strategies Stephen A. McClave, MD, AGAF; Reid A. Nishikawa, PharmD, BCNSP, FCSHP; and Carol R. Parrish, MS, RD C107; C207 Managing the Post-Bariatric Patient David C. Metz, MD, AGAF and John A. Martin, MD C108; C208 Issues in Colonoscopy Jerome D. Waye, MD, AGAF and John L. Petrini, Jr., MD C109; C209 Managing the Difficult Bleeder Loren A. Laine, MD, AGAF and Lauren B. Gerson, MD,MSc, AGAF C110; C210 Management of Difficult IBD Cases William J. Tremaine, MD and Maria T. Abreu, MD C111; C211 Handling the Complicated Functional Bowel Disease Patient Lin Chang, MD, AGAF and William D. Chey, MD, AGAF, FACG C112; C212 Difficult Cases in Managing Esophageal Issues Prateek Sharma, MD and Nicholas J. Shaheen, MD, MPH, AGAF C113; C213 Not attending a clinical challenge session

5 LEARNING OBJECTIVES Upon completion of this course, you will be able to Thoroughly comprehend the various management options for eosinophilic esophagitis, functional bowel disorders, pouchitis and refractory nausea and vomiting. Identify areas of controversy in the management of Barrett s esophagus, colorectal cancer screening, hepatitis C and ulcerative colitis. Implement new advances in evaluating and treating esophageal motility disorders, inherited colorectal cancer syndromes and hepatocellular carcinoma. Distinguish between the various approaches for diagnosing IBD-associated colorectal cancer, esophageal neoplasia and non-alcoholic fatty liver disease. Increase your knowledge of the newest modalities in non-invasive imaging of the colon, esophagus and liver. Develop treatment strategies using alternative approaches to the management of functional dyspepsia, pancreatic cysts and autoimmune hepatitis. Incorporate new endoscopic therapies for managing Barrett s esophagus, colorectal neoplasia and chronic pancreatitis. RE GIST RAT ION R E G I S T R AT I O N F E E S On or Before After April 2 April 2 and Onsite AGA Member $425 $500 Nonmember $575 $650 AGA Member Trainee $165 $240 Nonmember Trainee $265 $340 AGA Senior Member $155 $230 AGA Member Mid-Level Provider/Nurse $265 $340 Nonmember Mid-Level Provider/Nurse $365 $440 R E G I S T E R E A R LY A N D S A V E $ 7 5! Save $75 by registering on or before April 2. Early-bird registration ends on Friday, April 2, The $75 savings does not apply to registrations recieved after April 2 nor does it apply to onsite registration. If you register after April 2 you must pick up your DDW badge and registration materials on site. R E G I S T R AT I O N I S E A S Y Online... or By Phone (U.S. and Canada) (International) Hours: M-F, 9 a.m. - 5 p.m. EST R E F U N D P O L I C Y Refund requests must be received in writing on or before April 23. After April 2 such requests must include tickets and badges. All refunds, minus a $50 administrative fee, will be mailed following the course. A C C O M M O D AT I O N S Hotel reservations must be made through DDW Registration and Housing. Please refer to the DDW Preliminary Program for more information. C M E I N F O R M AT I O N The AGA Institute is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AGA Institute designates this educational activity for a maximum of 15 AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. P R O G R A M - R E L AT E D I N F O R M AT I O N Contact Anne Means, Manager, Educational Initiatives, at or ameans@gastro.org. SPRING POSTGRADUATE COURSE RESOURCES Course CD-ROM Online Sessions CD-ROM includes audio and slides of all lectures and clinical challenge sessions. CD-ROM will be available by June 1, View the sessions, including audio and slides online and earn CME. Sessions can be accessed by June 1, Pre-order and Save 10%! Plus! Purchase the CD-ROM and get the Online Sessions for just $10!

6 F A C U LT Y C O U R S E D I R E C T O R F A C U LT Y Sheila E. Crowe, MD, AGAF Digestive Health Center of Excellence C O - D I R E C T O R S Jorge A. Marrero, MD, MS Associate Professor, Internal Medicine Bruce E. Sands, MD, AGAF Acting Chief, Gastrointestinal Unit Associate Massachusetts General Hospital Harvard Medical School Faculty Disclosure In accordance with the ACCME s Standards for Commercial Support of Continuing Medical Education, all faculty and planning partners must disclose any financial relationship(s) or other relationship(s) held within the past 12 months. The AGA Institute implements a mechanism to identify and resolve all conflicts of interest prior to delivering the educational activity to learners. Neena S. Abraham, MD, MSCE, FACG, FASGE Assistant Baylor College of Medicine Maria T. Abreu, MD Chief, Division of Gastroenterology University of Miami School of Medicine Bruce R. Bacon, MD James F. King MD Endowed Chair in Gastroenterology Professor of Internal Medicine Director, Division of Gastroenterology & Hepatology Saint Louis University School of Medicine Peter A. Banks, MD, AGAF Director, Center for Pancreatic Disease Division of Gastroenterology Brigham and Women's Hospital Carl L. Berg, MD Chief of Gastroenterology and Hepatology Medical Director of Liver Transplantation William R. Brugge, MD, AGAF Director, GI Endoscopy Massachusetts General Hospital Michael Camilleri, MD, AGAF Atherton & Winifred W. Bean Professor; & Physiology College of Medicine Lin Chang, MD, AGAF Co-Director, Center for Neurobiology of Stress David Geffen School of Medicine University of California Los Angeles William D. Chey, MD, AGAF, FACG Director, GI Physiology Laboratory Health System Robert. R. Cima, MD, MA Associate Professor of Surgery Marcia R. Cruz-Correa, MD, PhD, AGAF Associate University of Puerto Rico Mark H. DeLegge, MD, AGAF University of South Carolina John K. DiBaise, MD Associate Glenn M. Eisen, MD, MPH, AGAF Associate Oregon Health and Science University Hashem B. El Serag, MD, MPH Baylor College of Medicine Grace H. Elta, MD, AGAF Professor, Department of Internal Medicine Ronnie Fass, MD Director, GI Motility Laboratory Southern Arizona VA Health Care Systems University of Arizona Health Sciences Center Brian G. Feagan, MD Director Robarts Research Institute Robert J. Fontana, MD Associate Professor of Internal Medicine Guadalupe Garcia-Tsao, MD Yale University School of Medicine Lauren B. Gerson, MD, MSc, AGAF Associate Stanford University Gregory G. Ginsberg, MD, AGAF Director of Endoscopic Services University of Pennsylvania Health System Gregory J. Gores, MD, AGAF Reuben R. Eisenberg and Physiology Chair, Division of Gastroenterology and Hepatology College of Medicine Gail A. Hecht, MD, MS, AGAF Chief of Digestive Disease and Nutrition University of Illinois at Chicago Ikuo Hirano, MD Associate Colin W. Howden, MD, AGAF John M. Inadomi, MD, AGAF University of California, San Francisco Peter J. Kahrilas, MD, AGAF Gilbert H. Marquardt Sunanda V. Kane, MD, MSPH, AGAF Associate Ciaran P. Kelly, MD, AGAF Beth Israel Deaconess Medical Center Arthur Asher Kornbluth, MD Clinical, Henry D. Janowitz Division of Gastroenterology Mount Sinai Medical Center Loren A. Laine, MD, AGAF USC School of Medicine Xavier Llor, MD Associate Professor University of Illinois at Chicago Anna S.F. Lok, MD, AGAF Professor of Internal Medicine Division of Gastroenterology John A. Martin, MD Associate Surgery Chief of Endoscopy Stephen A. McClave, MD, AGAF University of Louisville School of Medicine Kenneth R. McQuaid, MD, AGAF Chief of Gastroenterology Professor of Clinical Medicine San Francisco VA Medical Center University of California San Francisco David C. Metz, MD, AGAF University of Pennsylvania School of Medicine Reid A. Nishikawa, PharmD, BCNSP, FCSHP Director of Research; Coordinator, Clinical Services Nutrishare, Inc Carol R. Parrish, MS, RD Nutrition Support Specialist John L. Petrini Jr., MD Chief, Gastroenterology Sansum Clinic Associate Professor of Clinical Medicine USC School of Medicine David A. Peura, MD, AGAF Emeritus Professor David. W. Rattner, MD Chief, Division of General and Gastrointestinal Surgery Massachusetts General Hospital Rajender Reddy, MD Director of Hepatology Medical Director of Liver Transplantation University of Pennsylvania School of Medicine Miguel D. Regueiro, MD, AGAF Associate Clinical Head and Co-Director, Inflammatory Bowel Disease Center Director, Gastroenterology, Hepatology, and Nutrition Fellowship Program University of Pittsburgh Douglas K. Rex, MD Chancellor's Director of Endoscopy Indiana University Medical Center Suzanne Rose, MD, MSEd, AGAF Professor of Medical Education & Medicine, GI Division Associate Dean for Academic and Student Affairs Mount Sinai School of Medicine David T. Rubin, MD, AGAF Associate University of Chicago Donna H. Ryan, MD Associate Executive Director for Clinical Research Professor Pennington Biomedical Research Center Arun J. Sanyal, MD, FACP Charles Caravati Chairman, Division of Gastroenterology, Hepatology & Nutrition VCU Department of Internal Medicine Vijay H. Shah, MD Associate Nicholas J. Shaheen, MD, MPH, AGAF Associate and Epidemiology Director, Center for Esophageal Diseases and Swallowing University of North Carolina Chapel Hill Prateek Sharma, MD University of Kansas Stuart Sherman, MD & Radiology Indiana University Medical Center Cory A. Siegel, MD Director, Inflammatory Bowel Disease Center Dartmouth-Hitchcock Medical Center Stuart J. Spechler, MD, AGAF Chief, Division of Gastroenterology University of Texas Southwestern Medical Center Dallas VA Medical Center Christiana M. Surawicz, MD University of Washington Nicholas J. Talley, MD, PhD, AGAF Jacksonville Jayant A. Talwalkar, MD Associate Norah A. Terrault, MD Assistant University of California San Francisco William J. Tremaine, MD Professor of Gastroenterology Jerome D. Waye, MD, AGAF Clinical Mt. Sinai School of Medicine Cynthia M. Yoshida, MD, AGAF Private Practice Charlottesville, VA