C-type: For each numbered item, indicate whether it is associated with: (A) A only (B) B only (C) Both A and B (D) Neither A and B
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1 C-type: For each numbered item, indicate whether it is associated with: (A) A only (B) B only (C) Both A and B (D) Neither A and B ( ) 1. Most patients with epilepsia partialis continua show A. Focal EEG epileptiform abnormalities B. Poor response to antiepileptic medications Adams and Victor s Principles of Neurology, 8th edition, p.281 ( ) 2. Which of the following drugs increase the level of phenytoin? A. Amiodarone B. Verapamil Handbook of epilepsy treatment ( ) 3. Finding(s) suggestive of root avulsions following traumatic brachial plexopathy? A. Absent F responses. B. EMG: fibrillation potentials in cervical paraspinal muscles. Diagnosis and Management of Peripheral Nerve Disorders, p. 650 ( ) 4. Light- near dissociation pupil? A. Argyll Robinson pupil B. Dorsal midbrain syndrome Neurology in clinical practice, fourth edition, p.224 1
2 ( ) 5. Desynchronized sleep A. NREM B. REM Ans B Adam s, 8 th edition, P334 ( ) 6. Caudate atrophy can be found in which of the following conditions? A. Huntington s chorea B. Neuroacanthocytosis (both A & B) NICP:2148, 2152 ( ) 7. Hyperekplexia A. Origin of the pathological startle in the thalamus B. Clonazepam is the treatment of choice B Neurology in clinical practice 4 th ed. P2163 ( ) 8. Among parkinsonism-plus syndromes, palilalia is more commonly a feature of which disease(s)? A. Progressive supranuclear palsy B. Multiple system atrophy C Neurology in Clinical Practice, 4 th edition, 2004, p
3 ( ) 9. A patient presents to the ER with right hemiparesis and aphasia.the symptoms were present on awakening,less than an hour ago.routine labatory studies are normal.ct is normal.which is the best approach to treatment? A. Intravenous rt-pa B. Intra-arterial rt-pa D Principle of neurology eigth edition p694 ( ) 10. Which of the following are autosomal dominant cause of thromboemboic disease? A. Protein S deficiency B. Antithrombin-III deficiency Neurology in clinical practice fourth edition p ( ) 11. Functional brain imaging may offer the prospect of aiding the clinical diagnosis of dementias. Which of the following findings can help differentiate dementia with Lewy bodies (DLB) from AD? A. Occipital lobe hypoperfusion on SPECT B. Occipital lobe hypometabolism on PET Neurology in Clinical Practice, 4/e, pp ( ) 12. Upper motor neuron sign A. Friedreich ataxia B. Kugelberg-Welander syndrome Merritt s 11th ed p786, p862 3
4 ( ) 13. Opthalmoplegia can be seen in? A. Niemann-Pick disease type C B. Bassen-Kornzweig syndrome Merritt s Neurology, 11/e, 2005, p689, table 96.7 ( ) 14. Inborn errors with strokes? A. Fabry disease B. Menkes syndrome Merritt s Neurology, 11/e, 2005, p687, table 96.4 ( ) 15. Etiology of thunderclap headache A. Intracranial hypotension B. Subarachnoid hemorrhage Adams and Victor s Principles of Neurology, 8 th edition. p ( ) 16. Most of mitochondrial diseases is genetic diseases resulting in mitochondrial dysfunction, and which gene defect would involve these disorders A. Mitochondrial DNA (mtdna) B. Nucleus DNA (ndna) C Merritt s Neurology 11 th Edition, pp: 695 4
5 ( ) 17. Clinical feature(s) in meralgia paresthetica? A. Obesity, pregnancy, and diabetes mellitus may be contributory factors. B. Numbness, mild sensitivity of the skin and progressive muscle wasting at lateral thigh. Adams and Victor s Principles of Neurology 8 th edition, p ( ) 18. Anti-Jo1 antibody A. Polymyositis B. Inclusion body myositis Adams and Victor s Principles of Neurology, 8 th ed, p ( ) 19. About chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), which is CORRECT? A. Electrophysiologicaly, loss of late responses (F wave and H reflex) often noted in late stage of CIDP B. Electrophysiologicaly, multifocal conduction block and temporal dispersion seen frequently in CIDP B Principles of Neurology, 8th edition, p ( ) 20. Gomori Trichrome stain A. MERFF B. Nemaline rod myopathy Ans C (both correct) Neuropathology, Adams 8 th ed. P 1247, right lower last paragraph, line 3 5
6 ( ) 21. Chronic use of alcohol, barbiturate and benzodiazepine: A. Reduced rapid-eye movement (REM) sleep B. Reduced slow-wave sleep Adams and Victor s Neurology, 8 th edition, P.340 ( ) 22. Disease that result from abnormal mitochondrial function were more and more familiar by our knowledge, there are several causes for Mitochondrial DNA are more easily mutated than nuclear DNA, which statements are/is true about these causes? A. midna easily suffered from high concentrate free radical attacks B. midna have Nucleotide excision repair system & base excision repair system but no doubble-strand breakage repair system Cell & Molecular biology concepts and experiments 3e 2004, By Gerald Karp, p.213,572 ( ) 23. Acetylcholine A. Preganglionic sympathetic neurotransmitter B. Postganglionic sudomotor neurotransmitter ( ) 24. Norepinephrine A. Postganglionic sympathetic neurotransmitter B. Postganglionic sudomotor neurotransmitter A Principle of Neurology 8th ed., P ( ) 25. Decerebrate rigidity caused by lesion of? A. Vestibulospinal tract B. Rubrospinal tract Adams and Victor s Principles of Neurology, 8/e, 2005, p46 6
7 ( ) 26. The Kluver-Bucy syndrome is typically associated with lesions of? A. Amygdala B. Cingulate gyrus Kandel ER, Schwartz JH, Jessel TM: Principles of Neural Science, 4/e, 2000, p988 ( ) 27. The genetic test of Apolipoprotein E genotyping for sporadic Alzheimer s disease is A. A gold standard for diagnosis B. A reliable indicator for outcome prediction D Acta Neurol Taiwan. 2006;15(3): ( ) 28. The following is true for Anti-Hu, an autoantibody associated with paraneoplastic neurological syndrome: A. Its naming is based on a descriptive generic nomenclature basing on immunohistochemistry alone B. May be associated with Subacute Sensory Neuronopathy and the associated cancer is that of Small Cell Lung Cancer (SCLC) B Acta Neurol Taiwan, 2005;14:28-35 ( ) 29. Deep brain stimulation (DBS) in the treatment of Parkinson s disease A. High frequency stimulation of Subthalamic nucleus(stn) can modify and normalize the activity of STN neurons B. STN neurons showed marked decrease in burst and oscillatory activity during the dopamine depleting state of Parkinson s disease (PD) Acta Neurological Taiwanica Vol 15 No 2 Sep 2006, p206 7
8 ( ) 30. Herpes simplex virus,(hsv) is an DNA virus. Which type of HSV causes adult herpes simplex encephalitis? A. HSV type 1 B. HSV type 2 C Principles of Neurology 6 th edition, 1997, p ( ) protein Western blot positive in CSF A. New variant Creutzfeldt-Jakob disease B. Fatal familial insomnia D Merritts, 11 th ed. p ( ) 32. Ataxia is present in: A. Neuroacanthocytosis B. Abetalipoproteinemia B Merritte's Neurlogy 11 th ed. P674 ( ) 33. Multiple sclerosis A. Demyelination could be precipitated by viral infection. B. Human herpes virus 6 is implicated in its pathogenesis. Merritt s neurology, 11 th ed, p.943 ( ) 34. Increased signal in the globus pallidus in T1-weighted MRI A. Hepatic encephalopathy B. Renal encephalopathy Merritt s neurology 11 th ed. P1065 &1079 8
9 ( ) 35. Which of the following cancer has been associated with a paraneoplastic motor neuron disease? A. Breast cancer B. Small cell lung cancer Neurology in clinical practice, fourth edition, p.2262 ( ) 36. Atlantoaxial dislocation is commonly seen in: A. Down syndrome B. Ankylosing spondylitis Merritt s neurology 11 th ed. P1107 ( ) 37. Which plasma protein synthesized in the liver is vitamin-k dependent A. Protein-C B. Protein-S Meritt s Neruology 11th ed. P.1057 ( ) 38. Internuclear ophthalmoplegia is damage to the medial longitudinal fasciculus (MLF) between the third and sixth cranial nerves nuclei. Which of the following is (are) pseudointernuclear ophthalmoplegia (mimicking conditions)? A. Myasthenia gravis B. Thyroid orbitopathy Neurology in Clinical Practice, 4 th edition, 2004, p
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