Yorkshire General Histopathology EQA Case Response Analysis Circulation: R

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1 Yorkshire General Histopathology EQA Case Response Analysis Circulation: R Case number: 800 Number of responses: 70 Date: 13 MAY 09 Cystic lesion on thigh present 18/12 Age: 32 Subcutaneous tissue of thigh Irregular soft tissue 20 x 15 x 10 mm 1 Hidradenoma Glomangioma Eccrine hidrocystoma Benign skin appdge tumour?eccrine hydrocy Glomus tumour Eccrine acrospiroma Poroma (dermal) Spiradenoma 0.14 Highest scoring diagnosis: 1 with 7.37 Asterisks (if any) indicate dangerous diagnoses. Solid- cystic Hidradenoma Case number: 801 Number of responses: 69 Date: 13 MAY 09 Previous carcinoma rectum. Possible metastatic lesions RLL and RML. Age: 76 Wedge Resection right lower lobe Wedge of pleural covered lung tissue stapled on 3 sides and measuring 5.0 x 3.0 x 2.5cm. Slicing reveals a mottled pale brown nodule 2.0 x 1.5 x 2.5 cm maximum. The section is from the nodule. 1 Adenocarcinoma, poss/prob/def metastatic c Primary mucinous carcinoma lung Adenocarcinoma 0.00 Highest scoring diagnosis: 1 with Asterisks (if any) indicate dangerous diagnoses. from previously diagnosed carcinoma of rectum Immunos to distinguish prim or sec Metastatic adenocarcinoma c/w spread

2 Case number: 802 Number of responses: 70 Date: 13 MAY 09?Haemangioma R knee 30 years. Age: 58 Sex: Male Skin Ellipse of skin 16 x 7 x 6 mm with a raised dark blue lesion 7mm max. dimension 1 Glomus Tumour Glomangioma Hidradenoma cannot exclude glomangioma nee Skin adnexal tumour Metastatic carcinoma 0.01 Highest scoring diagnosis: 1 with 6.61 Asterisks (if any) indicate dangerous diagnoses. Glomangioma Case number: 803 Number of responses: 70 Date: 13 MAY 09 4 month history of non-healing lesion on ear. Age: 74 Skin 4mm Punch Biopsy 1 Chondrodermatitis nodularis helicis Solar elastotic nodule of ear Elastotic nodule of ear Solar elastosis Elastosis perforans serpiginosa Pseudoxanthoma elasticum Elastotic nodule perforating/pseudoanthoma 0.14 Highest scoring diagnosis: 1 with 8.36 Asterisks (if any) indicate dangerous diagnoses. Chondrodermatitis nodularis helicis 2

3 Case number: 804 Number of responses: 67 Date: 13 MAY 09 Right hemihepatectomy Age: 65 Liver, right hemihepatectomy Dark red lesion with spongy texture, measuring 100mm 1 Haemangioma Well differentiated angiosarcoma Haemangioma/haemangioendothelioma 0.15 Highest scoring diagnosis 1 with 9.78 Asterisks (if any) indicate dangerous diagnoses. Haemongioma Case number: 805 Number of responses: 67 Date: 13 MAY 09 Failed pregnancy Age: 29 Products of Conception Tissue fragments together measuring 16 x 4.5 x 3.5 cm 1 Complete hydatidiform mole Hydatidiform mole Hydatidiform mole?partial Complete hyd mole, v suggestive of chorioc 0.15 Highest scoring diagnosis 1 with 7.76 Asterisks (if any) indicate dangerous diagnoses. I favour complete mole karyotyping, refer Complete hydatidiform mole 3

4 Case number: 806 Number of responses: 68 Date: 13 MAY 09 Tumour found during vats pleurodesis for recurrent pneumothoraces. No Lymphademopathy?TB?Sarcoid. Age: 63 Right Lung Tumour Brown tissue, six fragments. Aggregate size 3.5 x 2.5 x 1.5 cm 1 Nodular amyloid Fibrous nodule Solitary fibrous tumour Hyaline fibrous plaque Sclerosing haemangioma/pneumocytoma Hyalinised/ sclerosed tumour - like lesion Fibrosis and healing granulation tissue Hyalinising granuloma/inflammatory pseudo Pneumothorax 0.15 Highest scoring diagnosis 1 with 8.78 Asterisks (if any) indicate dangerous diagnoses. Don't report lung resection work Amyloid Tumour Case number: 807 Number of responses: 70 Date: 13 MAY 09 2 year history of irritated lesion on lower back. Clinically irritated dermatofibroma. Age: 55 Skin biopsy Skin ellipse 16 x 7mm bearing a well-defined pale nodule 4 x 4mm. 1 Clear cell acanthorma Large cell acanthoma Acanthoma Eccrine poroma Hidroacanthoma simplex Clonal seborrhoeic keratosis 0.03 Highest scoring diagnosis 1 with 9.14 Asterisks (if any) indicate dangerous diagnoses. Clear cell acanthoma 4

5 Case number: 808 Number of responses: 69 Date: 13 MAY 09 Pain in knee - arthroscopy showed multiple lesions Age: 50 Sex: Male Material from left knee joint Multiple pale firm opaque fragments 1 Synovlal chondromatosis Highest scoring diagnosis 1 with Asterisks (if any) indicate dangerous diagnoses. Synovial chondromatosis Case number: 809 Number of responses: 68 Date: 13 MAY 09 Hartman's procedure for diverticular disease of sigmoid colon. 30mm Caecal polyp identified on endoscopy prior to reversal of Hartman's. Frozen section requested. Age: 54 Polyp from caecum 30mm polyp with slightly irregular surface. Macroscopically confined to mucosa with no submucosal invasion. 1 Serrated adenoma Serrated adenoma,low grade/moderate dyspl Metaplastic polyp Serrated adenoma, benign Tubulovillous adenoma with low grade dyspl Hyperplastic polyp Tubulovillous adenoma with high grade dysp Serrated adenoma with high grade dysplasia Peutz Jeghery type/ Colonic polyp Peutz Jeghery Mixed adenomatous hyperplastic polyp 0.03 Highest scoring diagnosis 1 with 5.97 Asterisks (if any) indicate dangerous diagnoses. Serrated adenoma 5

Circulation: Y Case number: 601 Number of responses: 80 Date: 30 NOV 12

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