6th European School of Dermato-Oncology: Update on Cutaneous Oncology (ESDO)

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Course Directors Matilda Bylaitė-Bučinskienė, Vilnius, Lithuania Claus Garbe, Tuebingen, Germany Axel Hauschild, Kiel, Germany Lidija Kandolf-Sekulović, Belgrade, Serbia 6th European School of

1 Course Directors Matilda Bylaitė-Bučinskienė, Vilnius, Lithuania Claus Garbe, Tuebingen, Germany Axel Hauschild, Kiel, Germany Lidija Kandolf-Sekulović, Belgrade, Serbia 6th European School of Dermato-Oncology: Update on Cutaneous Oncology (ESDO) January 18th 20th, 2018 H4 Hotel Berlin Alexanderplatz Berlin, Germany Preliminary Program (updated 02/11/2017)

3 1 Content European Association of Dermato-Oncology (EADO) 2 Target Audience 2 Educational Objectives 2 Course Organization 3 Program Overview 4 Program 6 Thursday, January 18 th, Friday, January 19 th, Saturday, January 20 th, Course Faculty 11 General Information 14 Registration Form 17 Sponsors 18

4 2 European Association of Dermato-Oncology (EADO) The EADO is a non-profit organization funded in 1999 to promote, coordinate and improve clinical and laboratory research activities in the field of skin cancer including primary and secondary prevention, early detection, clinical diagnosis and clinical and experimental research. EADO has organized many successful meetings and the upcoming ones are visible on the website ( The EADO initiates for the sixth time a course dedicated to fundamentals in skin cancer targeted to specialists and residents in the final phase of their resident program. They will benefit a comprehensive and updated course to improve their decision-making process for the management of all types and stages of skin cancer, from diagnosis, primary treatment and adjuvant treatment, to the management of locoregional disease and distant metastatic disease. Target Audience This 2,5-day educational course targets doctors who are actively involved in the treatment of skin cancer. Dermatologists or other specialists who have completed specialist training, or residents in the final year of their training program, are likely to gain the most from this course. Educational Objectives The principal aim of the course is to provide a comprehensive and detailed understanding of the decision-making process for the management of all types and stages of skin cancer. This will include diagnosis and primary treatment, management of locoregional disease and distant metastatic disease, and adjuvant treatment. This is particularly relevant given the rapid progress in our understanding of melanoma and non-melanoma skin cancer, and the development of new treatments. In particular delegates will acquire the following knowledge: 1. Strategies for diagnosis of melanoma, Merkel cell and non-melanoma skin cancer including dermoscopy and confocal laser microscopy. 2. The indications, risks and benefits and strategies for mole screening. 3. Diagnosis of skin cancer: how to break bad news. 4. The indications and methods for genetic diagnosis and genetic counseling of skin cancer patients. 5. The present AJCC staging systems and how to stage melanoma, Merkel cell and cutaneous squamous cell carcinoma, and other non-melanoma skin cancers.

5 3 6. The value of imaging and biomarkers for the detection of metastases and disease staging. 7. Adjuvant treatment of skin cancer: radiotherapy, immunotherapy, chemotherapy. 8. New systemic treatments for stage IV melanoma: targeted agents and immunotherapeutics. 9. New treatment options of advanced basal cell carcinoma. 10. New systemic treatments for advanced Merkel cell and squamous cell carcinoma. 11. The characteristics of mucosal and uveal melanomas and their treatment options. 12. Options for topical treatment of epithelial skin cancers. 13. The current classification of cutaneous lymphoma, staging and treatment options for different subtypes of cutaneous lymphoma. 14. Clinical trials in skin cancer: an update. 15. The indications and strategies for supportive treatments including best supportive care. Course Organization The course consists of plenary sessions and interactive outbreak sessions. Plenary sessions will comprise clear structured and up-to-date presentations followed by audience discussion. Voting devices will be used to respond to multiple choice questions. These questions may precede the presentation of the structured knowledge or may be presented at the end in order to test the level of knowledge the audience has gained. The main part of the course consists of 8 interactive sessions, each with no more than 30 attendants. Every participant takes part in each of these sessions which mainly comprise casebased discussion. These will be used to illustrate treatment pathways, how risk and benefit are assessed, and how management decisions are made. We look forward to welcoming you in Berlin in January 2018! Matilda Bylaitė-Bučinskienė, MD Claus Garbe, MD Axel Hauschild, MD Lidija Kandolf-Sekulović, MD Course Directors

6 4 Program Overview A commercial exhibition will be held on all days close to the meeting rooms. Thursday January 18 th, :00 9:00 10:00 11:00 12:00 Group I Group II Group III Group IV Lectures: Grenander 1 4 Course A+F: Grenander 1 Course B+E: Grenander 2 Course C+G: Grenander 3 Course D+H: Grenander 4 All meeting rooms are located on the ground floor. Friday January 19 th, 2018 Group I Group II Group III Group IV PLENARY SESSION 2 C. Garbe A. Hauschild C. Höller C. Robert Break COURSE C A. Stratigos COURSE D M. Weichenthal COURSE A A. Hauschild COURSE B C. Garbe Break COURSE D M. Weichenthal COURSE A A. Hauschild COURSE B C. Garbe COURSE C A. Stratigos Lunch Saturday January 20 th, 2018 Group I Group II Group III Group IV PLENARY SESSION 5 C. Lebbé U. Keilholz P. Arenberger C. Garbe Break COURSE G K. Peris COURSE H R. Kaufmann COURSE E C. Lebbé COURSE F L. Kandolf-Sekulovic Break COURSE H R. Kaufmann COURSE E C. Lebbé COURSE F L. Kandolf-Sekulovic COURSE G K. Peris

7 5 13:00 14:00 15:00 16:00 17:00 18:00 Welcome Session PLENARY SESSION 1 A. M. Forsea V. del Marmol J. J. Grob C. Garbe Break COURSE A A. Hauschild COURSE B C. Garbe COURSE C A. Stratigos COURSE D M. Weichenthal Break COURSE B C. Garbe COURSE C A. Stratigos COURSE D M. Weichenthal COURSE A A. Hauschild CUTANEOUS SIDE EFFECTS PLENARY TREATMENT SESSION 3 J. OPTIONS Malvehy S. P. Sardȧ C. Garbe I. Zalaudek Break COURSE E C. Lebbé COURSE F L. Kandolf-Sekulovic COURSE G K. Peris COURSE H R. Kaufmann Break COURSE F L. Kandolf-Sekulovic COURSE G K. Peris COURSE H R. Kaufmann COURSE E C. Lebbé EXAMINATIONS: EUROPEAN CERTIFICATE FOR MEDICAL TUMOR THERAPY IN DERMATOONCOLOGY

8 6 Program Thursday, January 18 th, :45 14:00 Welcome and course introduction Claus Garbe, Tuebingen, Germany PLENARY SESSION 1: Epidemiology of skin cancer Chairpersons: Matilda Bylaitė-Bučinskienė and Lidija Kandolf-Sekulovic 14:00 14:20 LECTURE 1: Epidemiology and early detection of skin cancer Grenander 1 4 Ana Maria Forsea, Bucharest, Romania 14:20 14:40 LECTURE 2: Who is at risk for melanoma and NMSC? Grenander 1 4 Veronique del Marmol, Brussels, Belgium 14:40 15:00 LECTURE 3: How to detect rapidly growing melanomas? Grenander 1 4 Jean Jacques Grob, Marseille, France 15:00 15:20 LECTURE 4: Can smart phone apps replace the dermatologist? Grenander 1 4 Claus Garbe, Tuebingen, Germany 15:20 15:30 Discussion 15:30 16:00 Coffee Break 16:00 17:00 COURSE A: Number needed to excise: Grenander 1 a critical parameter to avoid unnecessary nevi excisions Axel Hauschild, Kiel, Germany 16:00 17:00 COURSE B: Follow-up of melanoma Grenander 2 Claus Garbe, Tuebingen, Germany 16:00 17:00 COURSE C: How to manage non-melanoma skin cancer? Grenander 3 Alexander Stratigos, Athens, Greece 16:00 17:00 COURSE D: Diagnosis and management of cutaneous Grenander 4 lymphomas and hematological malignancies Michael Weichenthal, Kiel, Germany 17:00 17:30 Coffee Break

9 7 17:30 18:30 COURSE B: Follow-up of melanoma Grenander 2 Claus Garbe, Tuebingen, Germany 17:30 18:30 COURSE C: How to manage non-melanoma skin cancer? Grenander 3 Alexander Stratigos, Athens, Greece 17:30 18:30 COURSE D: Diagnosis and management of cutaneous Grenander 4 lymphomas and hematological malignancies Michael Weichenthal, Kiel, Germany 17:30 18:30 COURSE A: Number needed to excise: Grenander 1 a critical parameter to avoid unnecessary nevi excisions Axel Hauschild, Kiel, Germany Friday, January 19 th, 2018 PLENARY SESSION 2: Management of metastatic melanoma Chairpersons: David Moreno-Ramirez and Ricardo Vieira 08:00 08:20 LECTURE 5: Mutational testing in the routine and beyond Grenander 1 4 Claus Garbe, Tuebingen, Germany 08:20 08:40 LECTURE 6: Adjuvant therapies for high-risk melanoma: Grenander 1 4 an outlook Axel Hauschild, Kiel, Germany 08:40 09:00 LECTURE 7: Targeted therapy of metastatic melanoma Grenander 1 4 Christoph Höller, Vienna, Austria 09:00 09:20 LECTURE 8: Immune checkpoint inhibition Grenander 1 4 for metastatic melanoma Caroline Robert, Paris, France 09:20 09:30 Discussion 09:30 10:00 Coffee Break

10 8 10:00 11:00 COURSE C: How to manage non-melanoma skin cancer? Grenander 3 Alexander Stratigos, Athens, Greece 10:00 11:00 COURSE D: Diagnosis and management of cutaneous Grenander 4 lymphomas and hematological malignancies Michael Weichenthal, Kiel, Germany 10:00 11:00 COURSE A: Number needed to excise: Grenander 1 a critical parameter to avoid unnecessary nevi excisions Axel Hauschild, Kiel, Germany 10:00 11:00 COURSE B: Follow-up of melanoma Grenander 2 Claus Garbe, Tuebingen, Germany 11:00 11:30 Coffee Break 11:30 12:30 COURSE D: Diagnosis and management of cutaneous Grenander 4 lymphomas and hematological malignancies Michael Weichenthal, Kiel, Germany 11:30 12:30 COURSE A: Number needed to excise: Grenander 1 a critical parameter to avoid unnecessary nevi excisions Axel Hauschild, Kiel, Germany 11:30 12:30 COURSE B: Follow-up of melanoma Grenander 2 Claus Garbe, Tuebingen, Germany 11:30 12:30 COURSE C: How to manage non-melanoma skin cancer? Grenander 3 Alexander Stratigos, Athens, Greece 12:30 13:00 Lunch PLENARY SESSION 3: Interactive dermoscopy session (with voting system) Chairpersons: Josep Malvehy and Iris Zalaudek 13:00 13:30 LECTURE 9: Dermoscopic algorithm for melanoma diagnosis Grenander 1 4 Josep Malvehy, Barcelona, Spain 13:30-14:00 LECTURE 10: Facial lesions Grenander 1 4 Susana Puig Sardá, Barcelona, Spain

11 9 14:00 14:30 LECTURE 11: Acral lesions Grenander 1 4 Claus Garbe, Tuebingen, Germany 14:30 15:00 LECTURE 12: Pink tumors Grenander 1 4 Iris Zalaudek, Graz, Austria 15:00 15:30 Coffee Break 15:30 16:30 COURSE E: Organizing a skin cancer center Grenander 2 Celeste Lebbé, Paris, France 15:30 16:30 COURSE F: How to manage adverse effects of checkpoint Grenander 1 inhibitors and targeted therapy Lidija Kandolf Sekulovic, Belgrade, Serbia 15:30 16:30 COURSE G: Treatments of actinic keratosis and field cancerization Grenander 3 Ketty Peris, Rome, Italy 15:30 16:30 COURSE H: Surgical management of skin cancer: tips and tricks Grenander 4 Roland Kaufmann, Frankfurt, Germany 16:30 16:45 Coffee Break 16:45 17:45 COURSE F: How to manage adverse effects of checkpoint Grenander 1 inhibitors and targeted therapy Lidija Kandolf Sekulovic, Belgrade, Serbia 16:45 17:45 COURSE G: Treatments of actinic keratosis and field cancerization Grenander 3 Ketty Peris, Rome, Italy 16:45 17:45 COURSE H: Surgical management of skin cancer: tips and tricks Grenander 4 Roland Kaufmann, Frankfurt, Germany 16:45 17:45 COURSE E: Organizing a skin cancer center Grenander 2 Celeste Lebbé, Paris, France

12 10 Saturday, January 20 th, 2018 PLENARY SESSION 5: Update on hot topics in dermato-oncology Chairpersons: Axel Hauschild and Claus Garbe 08:30 08:50 LECTURE 13: The new AJCC classification for melanoma 2018 Grenander 1 4 Celeste Lebbé, Paris, France 08:50 09:20 LECTURE 14: Management of mucosal and ocular melanomas Grenander 1 4 Eckhart Kämpgen, Berlin, Germany 09:20 09:50 LECTURE 15: Rare skin cancers: what is your diagnosis? Grenander 1 4 Petr Arenberger, Prague, Czech Republic 09:50 10:00 Presidential address Grenander 1 4 Claus Garbe, Tuebingen, Germany 10:00 10:30 Coffee Break 10:30 11:30 COURSE G: Treatments of actinic keratosis and field cancerization Grenander 3 Ketty Peris, Rome, Italy 10:30 11:30 COURSE H: Surgical management of skin cancer: tips and tricks Grenander 4 Roland Kaufmann, Frankfurt, Germany 10:30 11:30 COURSE E: Organizing a skin cancer center Grenander 2 Celeste Lebbé, Paris, France 10:30 11:30 COURSE F: How to manage adverse effects of checkpoint Grenander 1 inhibitors and targeted therapy Lidija Kandolf Sekulovic, Belgrade, Serbia 11:30 12:00 Coffee Break 12:00 13:00 COURSE H: Surgical management of skin cancer: tips and tricks Grenander 4 Roland Kaufmann, Frankfurt, Germany 12:00 13:00 COURSE E: Organizing a skin cancer center Grenander 2 Celeste Lebbé, Paris, France 12:00 13:00 COURSE F: How to manage adverse effects of checkpoint Grenander 1 inhibitors and targeted therapy Lidija Kandolf Sekulovic, Belgrade, Serbia 12:00 13:00 COURSE G: Treatments of actinic keratosis and field cancerization Grenander 3 Ketty Peris, Rome, Italy 14:00 16:00 Examinations: European Certificate for Medical Tumor Therapy in Dermatooncology

13 11 Course Faculty A Petr Arenberger, MD Charles University 3rd School of Medicine Srobarova 50 CZ Prague, Czech Republic Phone: avemedica@ .cz B Matilda Bylaitė-Bučinskienė, MD Professor of Dermatology Consultant of the Centre of Dermatovenereology President of Lithuanian Association of Dermatovenereologists Vilnius University Hospital Santariskiu Klinikos Kairiukscio str Vilnius, Lithuania Phone: matilda.bylaite@santa.lt F Ana-Maria Forsea, MD Assistant Professor for Dermatology Carol Davila University of Medicine and Pharmacy Bucharest Bulevardul Eroii Sanitari Bucharest, Romania Phone: aforsea@yahoo.com G Claus Garbe, MD Professor of Dermatology Eberhard Karls University Liebermeister Str Tuebingen, Germany Phone: claus.garbe@med.uni-tuebingen.de Jean Jacques Grob, MD Professor of Dermatology Service de Dermatology and Cancer Research Hôpital de la Timone 264 Rue St. Pierre Marseille, France Phone: jean-jacques.grob@ap-hm.fr H Axel Hauschild, MD Professor of Dermatology University of Kiel Rosalind-Franklin-Str Kiel, Germany Phone: ahauschild@dermatology.uni-kiel.de

14 12 Christoph Höller, MD Professor of Dermatology Medical University of Vienna Waehringer Guertel Vienna, Austria Phone: ac.at K Eckhart Kämpgen, MD Dermatologikum Berlin Friedrichstraße Berlin, Germany Phone: kaempgen@ dermatologikum-berlin.de Lidija Kandolf Sekulovic, MD Professor of Dermatology Medical Faculty Military Medical Academy Crnotravska Belgrade, Serbia Phone: lkandolfsekulovic@gmail.com Roland Kaufmann, MD Professor of Dermatology, Director Clinical Center J. W. Goethe University Theodor-Stern-Kai Frankfurt/Main, Germany Phone: kaufmann@em.uni-frankfurt.de L Celeste Lebbé, MD Professor of Dermatology Hôpital Saint-Louis 1, Avenue Claude-Vellefaux Paris, France Phone: celeste.lebbe@aphp.fr M Josep Malvehy, MD Director of the Melanoma Unit Hospital Clinic of Barcelona C/Villarroel Barcelona, Spain Phone: jmalvehy@clinic.ub.es Véronique del Marmol, MD Porphyria Unit Department of Clinical Chemistry Erasme Hospital ULB Route de Lennik Brussels, Belgium Phone: v.marmol@drvdm.be David Moreno-Ramirez, MD University Hospital Virgen Macarena Calle Dr. Fedriani, Sevilla, Spain david.moreno.ramirez.sspa@ juntadeandalucia.es

15 13 P Ketty Peris, MD Catholic University of Rome Largo a Gemelli, Rome, Italy Phone: ketty.peris@unicatt.it Susana Puig Sardá, MD Hospital Clinic of Barcelona C/Villarroel 170 Barcelona, Spain Phone: susipuig@gmail.com R Caroline Robert, MD Head Dermatology Gustave Roussy Institute 114 rue Edouard Vaillant Villejuif, France Phone: caroline.robert@gustaveroussy.fr S V Ricardo Vieira, MD University of Coimbra Coimbra, Portugal ricardo.vieira@portugalmail.pt W Michael Weichenthal, MD Professor of Dermatology University of Kiel Rosalind-Franklin-Str Kiel, Germany Phone: mweichenthal@dermatology. uni-kiel.de Z Iris Zalaudek, MD Division of Dermatology and Venerology Non-Melanoma Skin Cancer Unit Medical University of Graz Auenbruggerplatz Graz, Austria Phone: iris.zalaudek@medunigraz.at Alexander Stratigos, MD University of Athens School of Medicine Andreas Sygros Hospital 5 Dragoumi Street Athens , Greece Phone: alstrat2@gmail.com

16 14 General Information Accommodation MedConcept has reserved a limited number of rooms under the reference "ESDO 2018" at the following hotels: H4 Hotel Berlin Alexanderplatz Rate per standard room and night: 89 Euro single/99 Euro double (breakfast included) H2 Hotel Berlin Alexanderplatz Rate per standard room and night: 84 Euro single/double (breakfast included) Booking deadline: December 4, 2017 For your individual room booking, please contact the hotel directly: Phone: +49 (0) , reservation.berlin.alex@h-hotels.com Cancellation Policy Cancellations must be received in writing by December 17, No refunds will be granted after that date. A processing fee of 30 Euro will be deducted from each cancelled registration. Substitutions are possible. To substitute a registration, please send an including the name of the original registrant and the name of the person substituting to mirja.christ@medconcept.org. The participant acknowledges that he/she has no right to lodge damage claims against the organizers should the holding of the meeting be hindered or prevented by unexpected, political or economic events or generally by force, or should the non-appearance of speakers or other reasons need program changes. With registration, the participant accepts this proviso. CME Credits An application for CME accreditation will be made. How to receive your CME Credits To obtain CME credits, please fill in the evaluation forms, which you will find in your course bag. To get your certificate of attendance with the CME credits please return the evaluation forms duly filled in to the registration desk.

17 15 Course Organization MedConcept Gesellschaft für medizinische Projekte mbh Ms. Mirja Christ Friedenstraße Neuenhagen b. Berlin, Germany Phone: +49 (0) Fax: +49 (0) Course Venue H4 Hotel Berlin Alexanderplatz Karl-Liebknecht-Str Berlin Phone: +49 (0) Exhibition Opening Hours Thursday, January 18: 13:00 18:30 Friday, January 19: 07:30 17:30 Saturday, January 20: 08:00 13:30 Fees Registration Fee of 380 Euro (incl. VAT) covers Admission to scientific sessions Welcome reception Admission to exhibition Coffee breaks and lunch Bag with course documents Certificate of attendance The participant acknowledges that he/she has no right to lodge damage claims against the organizers should the holding of the meeting be hindered or prevented by unexpected, political or economic events or generally by force, or should the non-appearance of speakers or other reasons need program changes. With registration, the participant accepts this proviso. The maximum number of delegates is 100. Places will be made available on a first come first served basis to all applicants. Registration will close as soon as the maximum is reached or latest on January 12, 2018.

18 16 Language and Translation The official language of the meeting will be English. Simultaneous translation will not be provided. Registration / Information Desk The registration desk is situated at the ground floor of the H4 Hotel Berlin Alexanderplatz. Opening hours Thursday, January 18: Friday, January 19: Saturday, January 20: Sustainability 12:00 19:00 h 07:30 18:00 h 07:30 14:00 h MedConcept is internally working on increasing its sustainability efforts and we would like to encourage all involved in the 6 th European School of Dermato-Oncology Meeting to minimize their environmental and social impacts. Ways to get involved: Travel by train or carbon offsetting your flights to Berlin and encourage your colleagues to do the same If travelling by car, car pool with your colleagues Use the recycling bins provided on-site Recycle your name-badge in the bin provided at the registration desk Recycle all brochures and promotional items not needed in the bin provided within the industrial exhibition Use the public transportation system in Berlin

19 17 Registration Form 6 th European School of Dermato-Oncology January 18 th 20 th, 2018 H4 Hotel Berlin Alexanderplatz Berlin, Germany First Name: Last Name: Professional Title: Degree: MD PhD RN PA-C Gender: Male Female Speciality: Institution: Address: City: Zip Code: Country: Phone: Fax: Fees Registration Fee of 380,00 Euro (incl. VAT) covers Admission to scientific sessions Admission to exhibition Bag with course documents Welcome reception Coffee breaks and lunch Certificate of Attendance Payment Method Bank Transfer: Registration can only be confirmed upon receipt of full payment. Credit Card: MasterCard Visa American Express Credit Card Number: Expiration Date: Security Code CCV: (MC/Visa 3 digits on back, AMEX 4 digits on front) Cardholder Name: Signature: An invoice will be send by to the given address. If the invoice address is different from the address given above, please send an including the name of the registrant and the full invoice address to mirja.christ@medconcept.org. By completing the registration form, the participant accepts the cancellation policy as stated in the course program. By completing the registration form, the participant accepts the general terms and conditions as well as the cancellation policy given on the congress website at and agrees that his/her data may be used, processed and published (e.g. within the list of participants) for organizational purposes of the event. The participant accepts that MedConcept will contact him/her by for organizational matters (e.g. the registration confirmation and invoice) and information related to the event. I accept until further notice that MedConcept will inform me about future events by . To Register Mail registration form to: MedConcept GmbH, Friedenstraße 58, Neuenhagen bei Berlin, Germany Fax registration form to: +49 (0) Register online:

20 18 Sponsors GOLD SPONSORS SILVER SPONSOR Euro Sponsorship BRONZE SPONSOR FURTHER SPONSORS Almirall Hermal GmbH (5,000 Euro Sponsorship)

4 th European School of Dermato-Oncology: Update on Cutaneous Oncology (ESDO)

4 th European School of Dermato-Oncology: Update on Cutaneous Oncology (ESDO) January 28 th 30 th, 2016 Berlin, Germany Course Directors Prof. Claus Garbe, Tuebingen, Germany Prof. Axel Hauschild, Kiel,