SIMPLIFIED CHIRAL SEPARATIONS. Lux Cellulose-1. Guaranteed Alternative. to CHIRALCEL OD-H. Exceptional Quality Sensibly Priced

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1 SIMPLIFIED IRAL SEPARATIS Lux ellulose- Guaranteed Alternative to IRALEL D- Exceptional Quality Sensibly Priced

2 Lux ellulose- ellulose tris(3,5-dimethylphenylcarbamate) This dimethyl cellulose selector is famous around the world for its ability to separate aromatic, conjugated, and other challenging chiral compounds. Advantages of using Lux ellulose- Proven universal selector Available in 3 µm, 5 µm, and 0 µm Sensibly priced Stable up to 300 bar (4,350 psi) Easy solvent switching Meet the Rest of the Lux Family! Lux ellulose- cellulose tris(3-chloro-4- methylphenylcarbamate) Lux ellulose-3 cellulose tris(4-methylbenzoate) Lux ellulose-4 cellulose tris(4-chloro-3- methylphenylcarbamate) Lux Amylose- amylose tris(5-chloro-- methylphenylcarbamate) A- A- A- A- l l l l l l l l l l l ackbone ellulose ellulose Backbone Backbone ellulose Backbone ellulose Backbone ellulose ellulose Backbone Backbone ellulose Backbone ellulose Backbone hlorinated ellulose ellulose Ester ellulose ellulose Backbone Backbone ellulose Backbone ellulose Backbone Amylose Amylose Backbone Backbone Amylose Backbone Amylose Backb hlorinated ellulose hlorinated Amylose The Lux line of SPs offers 5 complementary selectivities 00 Phenomenex, Inc. All rights reserved.

3 Guaranteed Alternative to IRALEL D- SIMPLIFIED IRAL SEPARATIS If Lux analytical columns ( 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE. Ambucetamide Lux 5 µm ellulose- a = App ID min onditions for both columns: Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Methanol / 0. % Diethylamine in Isopropanol (90:0) Flow Rate: ml/min Detection: 0 nm 74 *IRALEL 5 µm D- a =.83 0 Metoprolol Lux 5 µm ellulose- a =.38 omifensine min *IRALEL 5 µm D- a =.8 0 Lux 5 µm ellulose- a =.0 min min App ID 7454 App ID 743 App ID 74 App ID 744 onditions for both columns: Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Acetonitrile / 0. % Diethylamine in Isopropanol (95:5) Flow Rate: ml/min Detection: 0 nm 3 onditions for both columns: Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Acetonitrile / 0. % Diethylamine in Isopropanol (95:5) Flow Rate: ml/min Detection: 0 nm min *IRALEL 5 µm D- a =. App ID min 3

4 Specialized oating Process and Expert Packing Provides ptimal olumn Performance. ur robust coating and packing process allows you to enjoy increased loading capacity, column reproducibility, and exceptional enantiomeric resolution. Achieve the optimal efficiencies you desire without sacrificing chiral recognition abilities. Tolperisone Lux 5 µm ellulose- a =.09 App ID 73 onditions for both columns: Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in exane / 0. % Diethylamine in Isopropanol (90:0) Flow Rate: ml/min Detection: 0 nm min *IRALEL 5 µm D- a =.07 0 Metofoline Lux 5 µm ellulose- a = min min *IRALEL 5 µm D- a = min Temazepam Lux 5 µm ellulose- a =.39 App ID 745 App ID 7405 App ID 7404 App ID 73 3 onditions for both columns: l onditions for both columns: 3 Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Methanol / 0. % Diethylamine in Isopropanol (90:0) Flow Rate: ml/min Detection: 0 nm Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Acetonitrile / 0. % Diethylamine in Isopropanol (95:5) Flow Rate: ml/min Detection: 0 nm min 3 *IRALEL 5 µm D- a =.8 App ID 747 l min 4

5 Extreme Stability and Separating Power under SF onditions. ever fear crushed media or loss in efficiency again. With a pressure stability up to 300 bar (4,350 psi), you can feel confident about running at high operating pressures (if necessary). Lux media is SF approved and versatile enough to satisfy all of your chiral separation needs. SIMPLIFIED IRAL SEPARATIS Bifonazole onditions for both columns: Lux 5 µm ellulose- a = min *IRALEL 5 µm D- a =.0 Atenolol min min Lux 5 µm ellulose- a =.97 *IRALEL 5 µm D- a =.64 App ID 900 App ID 8855 App ID 90 App ID 9098 Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Methanol / arbon Dioxide (5:85) Flow Rate:.5 ml/min Temperature: 35 Detection: Diode Array Detector onditions for both columns: Dimensions: 50 x 4.6 mm Mobile Phase: 0. % Diethylamine in Methanol / arbon Dioxide (0:80) Flow Rate:.5 ml/min Temperature: 35 Detection: Diode Array Detector min 5

6 Easy hiral Method Development Resolve 9 % of your enantiomers with five complementary Lux phases.* To get you started, we have outlined a simple strategy for screening SPs under PL and SF conditions in our chiral method development solutions poster. all or go online today to create your own custom screening kit or to request a chiral method development solutions poster at *Based on screening 33 compounds on all five Lux Phases hiral Screening and Separation Services PL SF Preparative Training hiral Phase Screening Method ptimization Method Re-Validation Scale-Up Services n-site Training For more information on our services or to begin a project, please contact your local Phenomenex chiral expert or us at: phenologics@phenomenex.com You can also visit us on the web: 6

7 SIMPLIFIED IRAL SEPARATIS rdering Information 3 µm Analytical olumns (mm) SecurityGuard artridges (mm) 50 x.0 50 x.0 50 x x x x x.0* 4 x 3.0* Phases /0pk /0pk ellulose- 00B-4458-B0 00F-4458-B0 00B-4458-E0 00D-4458-E0 00F-4458-E0 00G-4458-E0 AJ0-840 AJ ellulose- 00B-4456-B0 00F-4456-B0 00B-4456-E0 00D-4456-E0 00F-4456-E0 00G-4456-E0 AJ AJ ellulose-3 00B-449-B0 00F-449-B0 00B-449-E0 00D-449-E0 00F-449-E0 00G-449-E0 AJ0-86 AJ0-86 ellulose-4 00B-4490-B0 00F-4490-B0 00B-4490-E0 00D-4490-E0 00F-4490-E0 00G-4490-E0 AJ0-866 AJ0-867 Amylose- 00B-447-B0 00F-447-B0 00B-447-E0 00D-447-E0 00F-447-E0 00G-447-E0 AJ0-847 AJ for ID: mm mm 5 µm Analytical olumns (mm) SecurityGuard artridges (mm) 50 x.0 50 x x x x x.0* 4 x 3.0* Phases /0pk /0pk ellulose- 00B-4459-B0 00B-4459-E0 00D-4459-E0 00F-4459-E0 00G-4459-E0 AJ0-840 AJ ellulose- 00B-4457-B0 00B-4457-E0 00D-4457-E0 00F-4457-E0 00G-4457-E0 AJ AJ ellulose-3 00B-4493-B0 00B-4493-E0 00D-4493-E0 00F-4493-E0 00G-4493-E0 AJ0-86 AJ0-86 ellulose-4 00B-449-B0 00B-449-E0 00D-449-E0 00F-449-E0 00G-449-E0 AJ0-866 AJ0-867 Amylose- 00B-447-B0 00B-447-E0 00D-447-E0 00F-447-E0 00G-447-E0 AJ0-847 AJ for ID: mm mm 5 µm Semi-Prep olumns (mm) SecurityGuard artridges (mm) 50 x x x 0.0 Phases /3pk ellulose- 00F G AJ ellulose- 00F G AJ ellulose-3 00F G AJ0-863 ellulose-4 00F G AJ0-868 Amylose- 00F G AJ0-847 for ID: 9 6 mm 0 µm Bulk Media 00 g kg Phases ellulose- 04G K-4473 ellulose- 04G K-4464 Amylose- Please inquire for 0 µm Lux Amylose-, ellulose-3 or ellulose-4 media. 5 µm Axia Packed Preparative olumns (mm) SecurityGuard artridges (mm) 50 x. 50 x. 50 x x 50 5 x.** 5 x Phases /ea /ea ellulose- 00F-4459-P0-AX 00G-4459-P0-AX 00G-4459-U0-AX 00G-4459-V0-AX AJ AJ ellulose- 00F-4457-P0-AX 00G-4457-P0-AX 00G-4457-U0-AX 00G-4457-V0-AX AJ AJ0-840 ellulose-3 00F-4493-P0-AX 00G-4493-P0-AX 00G-4493-U0-AX 00G-4493-V0-AX AJ0-864 AJ0-865 ellulose-4 00F-449-P0-AX 00G-449-P0-AX 00G-449-U0-AX 00G-449-V0-AX AJ0-869 AJ Amylose- 00F-447-P0-AX 00G-447-P0-AX 00G-447-U0-AX 00G-447-V0-AX AJ AJ for ID: 8 9 mm mm *SecurityGuard Analytical artridges require holder, Part o. : KJ0-48 SemiPrep SecurityGuard artridges require holder, Part o. : AJ0-70 **PREP SecurityGuard artridges require holder, Part o. : AJ PREP SecurityGuard artridges require holder, Part o. : AJ µm Method Screening Kits (save 0 % when purchased as a kit) 50 x 4.6 mm 50 x 4.6 mm Screening Kit K K0-848 Kit contains one column of each phase. olumn Performance heck Standard Part o. Description Unit Price AL0-84 hiral Test Mix o. 5 (Lux) ea Terms and onditions Subject to Phenomenex Standard Terms & onditions, which may be viewed at Trademarks IRALEL and D- are registered trademarks of DAIEL hemical Industries, Ltd. Axia, Lux, and SecurityGuard are trademarks of Phenomenex, Inc. Disclaimer omparative separations may not be representative of all applications. olumns used for comparison were manufactured by DAIEL hemical Industries, Ltd. Phenomenex is not affiliated with DAIEL hemical Industries. 00 Phenomenex, Inc. All rights reserved. If Lux analytical columns ( 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE. 7

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