Optical Coherence Tomography

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1 Biological and Medical Physics, Biomedical Engineering Optical Coherence Tomography A Clinical and Technical Update Bearbeitet von Rui Bernardes, José Cunha-Vaz 1. Auflage Buch. XV, 255 S. Hardcover ISBN Format (B x L): 15,5 x 23,5 cm Gewicht: 573 g Weitere Fachgebiete > Medizin > Human-Medizin, Gesundheitswesen > Medizintechnik, Medizinische Werkstoffe schnell und portofrei erhältlich bei Die Online-Fachbuchhandlung beck-shop.de ist spezialisiert auf Fachbücher, insbesondere Recht, Steuern und Wirtschaft. Im Sortiment finden Sie alle Medien (Bücher, Zeitschriften, CDs, ebooks, etc.) aller Verlage. Ergänzt wird das Programm durch Services wie Neuerscheinungsdienst oder Zusammenstellungen von Büchern zu Sonderpreisen. Der Shop führt mehr als 8 Millionen Produkte.

2 Contents 1 Diabetic Macular Edema... 1 Conceição Lobo, Isabel Pires, and José Cunha-Vaz 1.1 Introduction Pathophysiology of Retinal Edema Extracellular Edema Starling s Law Incidence and Prevalence of DME Clinical Evaluation of Macular Edema Diagnosis and Classification... 4 References Ischemia Suk Ho Byeon, Min Kim, and Oh Woong Kwon 2.1 Retinal Ischemia Brief Anatomy of Retinal Circulation Fluorescein Angiography (FA) and Optical Coherence Tomography (OCT): Anatomic Correlations External Fovea in OCT Detection of Ischemic Retinal Area: Comparisons Between Fluorescein Angiography and OCT Pathologic Changes and Relevant OCT Findings in Ischemic Tissues Prominent Middle Limiting Membrane Retinal Artery Occlusion Central Retinal Artery Occlusion CRAO with Cilioretinal Artery Sparing Cilioretinal Artery Occlusion Branched Retinal Artery Occlusion Ophthalmic Artery Occlusion Cotton Wool Spots Combined CRAO and CRVO vii

3 viii Contents 2.16 Ocular Ischemic Syndrome Evaluation of Retinal Perfusion State on OCT Central retinal vein occlusion (CRVO) Central retinal vein occlusion Diabetic Retinopathy Diabetic Ischemic Maculopathy Choroidal Ischemia References Optical Coherence Tomography and Visual Acuity: Photoreceptor Loss Adzura Salam, Ute Ellen Kathrin Wolf-Schnurrbusch, and Sebastian Wolf 3.1 Introduction Principle of SD-OCT SD-OCT in Normal Eyes SD-OCT in Retinal Diseases Correlation Between Visual Acuity and Integrity of Photoreceptor in Retinal Diseases Photoreceptor Diabetic Macular Edema Retinal Vein Occlusion Retinal Artery Occlusion Age-Related Macular Degeneration Central Serous Chorioretinopathy Retinitis Pigmentosa Foveal Microstructure and Visual Acuity in Selected Surgical Retina Cases Conclusion Summary for Doctor References Optical Coherence Tomography Updates on Clinical and Technical Developments. Age-Related Macular Degeneration: Drusen and Geographic Atrophy Monika Fleckenstein, Steffen Schmitz-Valckenberg, and Frank G. Holz 4.1 Introduction Early AMD In Vivo Visualization of Drusen and Pigmentary Changes by Spectral-Domain Optical Coherence Tomography Quantification of Drusen Volume by Spectral-Domain Optical Coherence Tomography... 91

4 Contents ix 4.3 Geographic Atrophy Phenotypic Features of Atrophy and Identification of Predictive Markers by Spectral-Domain Optical Coherence Tomography Correlation with Other Imaging Modalities Quantification of Atrophy by Spectral- Domain Optical Coherence Tomography Imaging Future Perspectives References Optical Coherence Tomography in Glaucoma Fatmire Berisha, Esther M. Hoffmann, and Norbert Pfeiffer 5.1 Introduction Imaging in Glaucoma Time-Domain Optical Coherence Tomography in Glaucoma Spectral Domain Optical Coherence Tomography in Glaucoma Diagnostic Ability of Spectral Domain OCT in Glaucoma Future Directions of Optical Coherence Tomography in Glaucoma References Anterior Segment OCT Imaging Alexandre Denoyer, Antoine Labbé, and Christophe Baudouin 6.1 Introduction Principles of Anterior Segment OCT Clinical Applications Corneal Thickness Assessment Corneal Grafts Corneal Refractive Surgery Phakic Intraocular Lens Glaucoma Conclusion References Optical Coherence Tomography: A Concept Review Pedro Serranho, António Miguel Morgado and Rui Bernardes 7.1 Introduction The Genesis of OCT The Physical Principle Low-Coherence Light Interferometer Time-Domain Optical Coherence Tomography Spectral-Domain Optical Coherence Tomography Swept-Source Optical Coherence Tomography Polarization-Sensitive Optical Coherence Tomography

5 x Contents 7.9 Full-Field Optical Coherence Tomography Quantum Optical Coherence Tomography Latest Developments and Future Directions References Evaluation of the Blood Retinal Barrier with Optical Coherence Tomography Rui Bernardes and José Cunha-Vaz 8.1 Introduction Blood Retinal Barrier Clinical Evaluation of the Blood Retinal Barrier Quantitative Evaluation of the Blood Retinal Barrier Confocal Scanning Laser Ophthalmoscopy Retinal Leakage Analyzer Noninvasive Evaluation of Blood Retinal Barrier with OCT Data of Healthy Volunteers vs. Patient Data Differences Within the Same Eye and Scan Automatic Classification Conclusions References Polarization Sensitivity U. Schmidt-Erfurth, F. Schlanitz, M. Bolz, C. Vass, J. Lammer, C. Schütze, M. Pircher, E. Götzinger, B. Baumann, and C.K. Hitzenberger 9.1 Polarization-Sensitive Optical Coherence Tomography Principles of Polarization-Sensitive OCT Polarization Properties of Ocular Structures Segmentation Algorithms Imaging of the Eye with Polarization-Sensitive OCT Age-Related Macular Degeneration Glaucoma Diabetic Maculopathy Conclusion and Future Directions References Adaptive Optics in Ocular Optical Coherence Tomography Enrique Josua Fernández and Pablo Artal 10.1 Introduction The Eye as an Optical System and Adaptive Optics Transverse Resolution in OCT Effect of Aberration Correction in Contrast and Resolution Correction of Ocular Monochromatic Aberrations in OCT Time Domain Frequency Domain

6 Contents xi 10.6 Aberration Pancorrection in UHR OCT: Toward Isotropic and Subcellular Resolution Pancorrection: Full Aberration Correction UHR OCT and Pancorrection of Aberrations Summary References The SL SCAN-1: Fourier Domain Optical Coherence Tomography Integrated into a Slit Lamp F.D. Verbraak and M. Stehouwer 11.1 Introduction The SL SCAN-1 Device Scanning the Anterior and the Posterior Segment Scanning the Periphery with the SL SCAN Scanning Through a Three-Mirror Contact Lens with the SL SCAN Scanning with the Fundus Viewer, an Add-On Lens Examples of Subjects Studied Results Scans of the Posterior Pole Obtained Through a Handheld Lens (Posterior Mode) Scans of the Peripheral Retina Obtained Through a Handheld Lens or Three-Mirror Lens (Posterior Mode) Scans of the Anterior Segment Obtained Directly (Anterior Mode) and Through a Three-Mirror Lens (Posterior Mode) Thickness Measurements of the Posterior Segment with the Fundus Viewer and FastMap (Posterior Mode) Discussion References Index

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