Lux. Five Distinct Polysaccharide Phases to Resolve 92 % of Your Enantiomers* Lux Cellulose-1. Lux Cellulose-3. Lux Cellulose-2.

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1 Five Distinct Polysaccharide Phases to Resolve 9 % of Your Enantiomers* If Lux analytical columns ( 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE. Lux columns offer a wide and complementary range of enantioselectivity for even the most difficult chiral separation projects. igh efficiency and loading capacity Stable in ormal Phase, Polar rganic, SF, and Reversed Phase onditions 3 µm and 5 µm packed columns and µm bulk media for scale up Technical Specifications Particle Size 3, 5, * µm p Stability -9 Maximum Pressure 3 bar Temperature Range -5 Shipping Solvent n-exane/-propanol (9:, v/v) SF Please inquire for availability ellulose-- Lux chiral columns are made with high quality silica, and undergo a specialized coating and packing process that ensures high efficiencies while maintaining essential enantiorecognition abilities. l l Lux ellulose- ellulose tris(3,5-dimethylphenylcarbamate) chiral lc LuX l ellulose-- ellulose- Lux ellulose- ellulose tris(3-chloro-4-methylphenylcarbamate) Lux ellulose-3 ellulose tris(4-methylbenzoate) l l ellulose-- Amylose-- Lux ellulose-4 ellulose tris(4-chloro-3-methylphenylcarbamate) Lux Amylose- Amylose tris(5-chloro--methylphenylcarbamate) * Based on 33 compounds screened on all five Lux phases Phenomenex 85

2 Achieve ptimal Resolution by Screening all Five omplementary Lux hiral olumns Utilizing differences in selectivity can help develop methods more efficiently by offering broad and contrasting chiral recognition abilities. Lux chiral selectors provide a variety of selectivities that give you the opportunity to screen for the ideal chiral separation. Etozolin SF LUX chiral lc Lux ellulose- a =.6 Lux ellulose-4 a =.35 Lux Amylose- a =.45 Lux ellulose- a =.48 App ID 948 App ID 946 App ID 95 App ID 947 onditions for all columns: Dimensions: 5 x 4.6 mm Mobile Phase: Acetonitrile /. % Diethylamine in mm 4 3 (6:4) Flow Rate: ml/min Detection: nm S ptimal Resolution Lux ellulose-3 a =.7 App ID 95 Based on a five phase screen under reversed phase conditions, the optimal chiral stationary phase for resolving Etozolin is Lux ellulose-3. omparative separations may not be representative of all applications. 86 Phenomenex

3 Lux hiral Stationary Phases The Lux line of cellulose and amylose-based chiral stationary phases includes five complementary selectivities. Lux Amylose-: hlorinated Amylose hiral Selector This first-to-market chlorinated amylose phenylcarbamate derivative offers complex chiral recognition components that greatly increase the chances of achieving chiral resolution. l Amylose-- Amylose tris(5-chloro--methylphenylcarbamate) -Phenylcyclohexanone Lux 5 µm Amylose- a =.4 App ID 898 a =.4 *IRALPAK 5 µm AD - App ID 897 onditions for both columns: Dimensions: 5 x 4.6 mm Mobile Phase:. % Diethylamine in exane /. % Diethylamine in Isopropanol (9:) Flow Rate: ml/min Detection: nm min min SF Lux ellulose-: Dimethyl ellulose hiral Selector This universally trusted cellulose phenylcarbamate derivative is absolutely essential to any chiral screen. Metoprolol a =.38 Lux 5µm ellulose- App ID 74 a =.6 *IRALEL 5µm D- App ID 743 ellulose-- ellulose tris(3,5-dimethylphenylcarbamate) onditions for both columns: Dimensions: 5 x 4.6 mm Mobile Phase:. % Diethylamine in Acetonitrile /. % Diethylamine in Isopropanol (95:5) Flow Rate: ml/min Detection: nm chiral lc LuX min omparative separations may not be representative of all applications. Phenomenex 87

4 Lux ellulose-: hlorinated ellulose arbamate Phase This first-to-market halogenated cellulose phenylcarbamate derivative offers unique chiral recognition abilities that complement the rest of the Lux family of columns. l ellulose-- Tolperisone a =.69 Lux 5 µm ellulose- App ID a =.7 *IRALEL 5 µm D- App ID 73 ellulose tris(3-chloro-4-methylphenylcarbamate) onditions for both columns: Dimensions: 5 x 4.6 mm Mobile Phase:. % Diethylamine in exane /. % Diethylamine in Isopropanol (9:) Flow Rate: ml/min Detection: nm 4 6 min 4 6 min 3 3 SF LUX chiral lc Lux ellulose-3: ellulose Ester Phase This cellulose methylbenzoate derivative offers distinct and complementary chiral recognition abilities. ellulose- Disopyramide a =.8 R s =.3 Lux 5 µm ellulose-3 App ID min a =.7 R s =.3 *IRALEL 5 µm J- App ID min ellulose tris(4-methylbenzoate) onditions for both columns: Dimensions: 5 x 4.6 mm Mobile Phase:. % Diethylamine in exane /. % Diethylamine in Ethanol (9:) Flow Rate: ml/min Detection: nm omparative separations may not be representative of all applications. 88 Phenomenex

5 Lux ellulose-4: hlorinated ellulose arbamate Phase This chlorinated cellulose phenylcarbamate derivative offers unique chiral recognition abilities. l ellulose-- ellulose tris(4-chloro-3-methylphenylcarbamate) Tolperisone a =.7 Lux 5 µm ellulose-4 App ID 953 *IRALPAK 5 µm AD - a =. App ID 955 onditions for all columns: Dimensions: 5 x 4.6 mm Mobile Phase:. % Diethylamine in exane /. % Diethylamine in Isopropanol (9:) Flow Rate: ml/min Detection: nm 4 6 min 4 6 min 3 3 omparative separations may not be representative of all applications. SF hiral Screening and Separation Services PL SF Preparative Training For more information on our services or to begin a project, please contact your local Phenomenex chiral expert or us at: phenologix@phenomenex.com You can also visit us on the web at: chiral lc LuX Phenomenex 89

6 If Lux analytical columns ( 4.6 mm ID) do not provide at least an equivalent or better separation as compared to a competing column of the same particle size, similar phase and dimensions, send in your comparative data within 45 days and keep the Lux column for FREE. rdering Information 3 µm Analytical olumns (mm) SecurityGuard artridges (mm) Phases 5 x. 5 x. 5 x 4.6 x x x x.* 4 x 3.* /pk /pk ellulose- B-4458-B F-4458-B B-4458-E D-4458-E F-4458-E G-4458-E AJ-84 AJ-843 ellulose- B-4456-B F-4456-B B-4456-E D-4456-E F-4456-E G-4456-E AJ-8398 AJ-8366 ellulose-3 B-449-B F-449-B B-449-E D-449-E F-449-E G-449-E AJ-86 AJ-86 ellulose-4 B-449-B F-449-B B-449-E D-449-E F-449-E G-449-E AJ-866 AJ-867 Amylose- B-447-B F-447-B B-447-E D-447-E F-447-E G-447-E AJ-847 AJ-847 for ID:. 3. mm mm SF 5 µm Analytical olumns (mm) SecurityGuard artridges (mm) Phases 5 x. 5 x 4.6 x x x x.* 4 x 3.* /pk /pk ellulose- B-4459-B B-4459-E D-4459-E F-4459-E G-4459-E AJ-84 AJ-843 ellulose- B-4457-B B-4457-E D-4457-E F-4457-E G-4457-E AJ-8398 AJ-8366 ellulose-3 B-4493-B B-4493-E D-4493-E F-4493-E G-4493-E AJ-86 AJ-86 ellulose-4 B-449-B B-449-E D-449-E F-449-E G-449-E AJ-866 AJ-867 Amylose- B-447-B B-447-E D-447-E F-447-E G-447-E AJ-847 AJ-847 for ID:. 3. mm mm LUX chiral lc 5 µm Semi-Prep olumns (mm) SecurityGuard artridges (mm) Phases 5 x. 5 x. x. /3pk ellulose- F G AJ-844 ellulose- F G AJ-8399 ellulose-3 F G AJ-863 ellulose-4 F-449- G-449- AJ-868 Amylose- F-447- G-447- AJ-847 for ID: 9 6 mm µm Bulk Media Phases g kg ellulose- 4G K-4473 ellulose- 4G K-4464 Please inquire for µm Lux Amylose-, ellulose-3 or ellulose-4 media. 5 µm Axia Packed Preparative olumns (mm) SecurityGuard artridges (mm) Phases 5 x. 5 x. 5 x 3 5 x 5 5 x.** 5 x 3. + /ea /ea ellulose- F-4459-P-AX G-4459-P-AX G-4459-U-AX G-4459-V-AX AJ-845 AJ-846 ellulose- F-4457-P-AX G-4457-P-AX G-4457-U-AX G-4457-V-AX AJ-84 AJ-84 ellulose-3 F-4493-P-AX G-4493-P-AX G-4493-U-AX G-4493-V-AX AJ-864 AJ-865 ellulose-4 F-449-P-AX G-449-P-AX G-449-U-AX G-449-V-AX AJ-869 AJ-863 Amylose- F-447-P-AX G-447-P-AX G-447-U-AX G-447-V-AX AJ-8473 AJ-8474 for ID: 8 9 mm 3 49 mm *SecurityGuard Analytical artridges require holder, Part o. : KJ-48 SemiPrep SecurityGuard artridges require holder, Part o.: AJ-7 **PREP SecurityGuard artridges require holder, Part o. : AJ-83 PREP SecurityGuard artridges require holder, Part o. : AJ µm Method Screening Kits (save % when purchased as a kit) 5 x 4.6 mm 5 x 4.6 mm Screening Kit K-8483 K-848 Kit contains one column of each phase. olumn Performance heck Standard Part o. Description Unit Price AL-84 hiral Test Mix o. 5 (Lux) ea *IRALPAK, IRALEL, AD, D-, and J- are registered trademarks of DAIEL hemical Industries, Ltd. olumns used for comparison were manufactured by DAIEL hemical Industries, Ltd. 9 Phenomenex