Supplementary Data to Supplementary Figure 1a to 1c

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1 UBC ATP13A2 UBA52 GAK HSPA4 RAB1A DNM1L SPG11 2DA2_HUMAN A30 ACMSD ADH1A ADH1B ATXN2 ATXN3 CAT CYP1B1 CYP2A6 CYP2B6 CYP2C19 CYP2J2 CYP3A43 CYP3A5 CYP4X1 FBXO7 GIGYF2 GSTO1 GSTO2 HLA-DQA2 HLA-DXA HRAS HSP90AA1 HTRA2 IGKV1-17 IKBKAP MAOB MAPT MC1R MCCC1 NAT2 NOS1 NR4A2

2 PLA2G6 PSEN1 SEMA5A SLC6A3 IP SOD2 SRGAP2 SYT11 TUBB3 UCHL1 VAMP3 SKP1 CUL1 EPS15 HIP1R CACNA1S CHRNB2 COMT CYP3A4 FAM47E HTR2A KCNJ6 MIR3656 PDXK TBP TRAPPC4 DNAJB1 DNAH8 SRGAP3 AKT1 CASP3 CYCS GP1BB LOC MFN2 PACRG PSEN2 PTEN SEPT5 SLC18A2 SOD1 SQSTM1

3 TH UBB UBE2K UBE2S VDAC1 SNCB STUB1 APOE GAPDH PRNP TFDP1 TSPO CYP1A2 EGFR BACE1 VCP BECN1 NOX1 COPS5 LOC SYT12 DYRK1A HLA-DRB5 RING1 RING1p TNS1 GDNF RPS27A AR BING2 CALM2 DAXX KEAP1 LOC MAP3K5 NFE2L2 NONO NQO1 PIAS2 PPIF SIRT2 SLC25A14 SLC25A27 CCDC62

4 HSPA8 SNORD14D ALPL ALPP ALPPL2 GSK3B ACTB ACTG1 CSN1S1 GFAP PSMA7 PTPN2 TP53 UBE2H UBE2I VIM BAG5 CYP20A1 CYP2D6 NGF CHRNA4 LOC CDC37 DIF TNF ATP6V1A IGF2R STX6 CD34 EEA1 WDR12 LAMP1 HDAC2 PSMA4 PSMD14 TOP1 UBA2 PSMC6 SORL1 YWHAB YWHAQ HERPUD1 DGKQ NUCKS1 PM20D1

5 SLC41A1 SLC45A3 STK39 USP24 HSPA1A HSPA1B HSPBP1 VAMP2 CFTR APP BDNF CALU CASP9 CDK5R1 CSNK1A1 CTNND1 DDC DRB1 FBXW7 FHIT GPR37 HDAC4 HLA-DRB1 HTT PIK3CB PIK3CD RANBP2 RGPD3 SH3GL1 SH3GL2 SH3GL3 TGFBI UBE2G1 UBE2G2 UBE2L3 WWOX PITX3 BAX BCL2L1 ERBB2 IGF1 LOC SUMO2 TRAF6 TYR

6 VDAC2 ALS2 CALM1 CALM3 DYRK2 GCH1 HAVCR1 MT-ND5 ND5 TUBA1A GAD2 KARS MAP1B NDUFA1 RELN MFN1 RHBDL1 LOC TRAP1 ACO2 C1QBP CDK16 DECR1 MAP3K14 PSMD2 SLC2A1 SLC8A1 TOMM20 HSPA5 HSPA9 ALB CD4 FTH1 IL2 IL6 INS INS-IGF2 LDLR PGK1 POLA1 POLD1 POLE REV3L TF AGO1

7 AIMP2 CARD9 DVL1 DVL2 DVL3 EIF2C1 EIF4EBP1 GLO1 JUN MAP3K12 MAP3K13 MBP MKKS P4HB PARD3 PARD6A PRKCZ WNT5A CCL18 PPARG ALDH5A1 ANKRD45 ARL5B ARL6IP1 ATL2 C9orf72 CCNK CCNT1 CCNT2 CEBPZ CPEB2 CRELD2 CTCFL DBP2 DBR1 DDHD2 DERL3 DHX16 DNAJA3 DNAJB12 DNAJB13 DNAJB14 DNAJC1 DNAJC10 DNAJC14

8 DNAJC18 DNAJC19 DNAJC22 DNAJC28 DNAJC3 DNAJC7 DYNC1H1 EDEM3 EIF2AK2 EPS15L1 ERBB2IP ERO1L ERO1LB FADS3 FAM58A FGFR1OP2 GCC2 HSPA12A HSPA12B HSPA13 HSPA14 HSPA1L HSPA4L HSPA6 HSPB8 HSPH1 LOC MAGOHB MSL2 PHACTR2 PRPF19 RAB5C RBM5 SBNO1 SCFD1 SEC22A SEC22B SEC22C SF3A2 SGTA SLC9A11 SLC9C2 SNAP23 SNAP29 SNAP47

9 SNW1 STAG1 STEAP4 STK10 STX11 STX19 STX2 STX3 STX4 STXBP1 STXBP2 STXBP3 SYNCRIP SYT14 TBC1D7 TBL1XR1 TFIP11 TM6SF1 TPR TXLNA TXLNB TXLNG USP34 VAMP1 VAMP4 VAMP7 VPS33B WASF2 ZFYVE20 ZMAT A1BG A4GALT ABCA12 ABCB1 ABHD6 ACER1 ACER2 ACP2 ACPP ADA AIM1 ALDH3A2 AMY2A

10 AMY2B ANO7 ARSA ARSB ARSD ARSH ASAH1 ASAH2 ATP1A1 ATP1A4 ATP6V1B2 AZU1 B3GALNT1 B4GALNT1 B4GALT6 BOD1 BSG C1orf131 C1orf85 CD1D CD38 CD68 CD79A CDSN CERK CERS6 CGA CHIT1 CLN3 CLN8 COMP CRLS1 CSF2 CSF3 CSTB CTSK CTSL CTSL1 DEGS1 DEGS2 DHFR DPAGT1 DSG1 EGR2 ENPP7

11 F8 F9 FA2H FAM189B FCGR2A FLG FLJ93471 FSHB G6PD GAA GALC GANAB GANC GATM 2 GBE1 GJB1 GLA GLB1 GM2A GSR GUSB GYPC HEXA HEXB HEXDC HLA HLA-A*03 HLA-A*2410 HLA-A*33 HLA-A26 HLA-B* HLA-B*3531 HLA-G HMGCR IDS IDUA ILF3 IVL KIF1B KLK2 KLK5 KLK7 KLKB1 LASS1

12 LASS6 LCT LGSN LHB LOR LRBA LRCH2 MANBA MAP9 MCM8 MFSD10 MGAM MGAT4C MOGS MPZ MRC1L1 MRPS22 MSMB MTX1 MUC1 NAGA NAGLU NAGS NEU1 NEU1p NPC1 NPC2 OGT PLA2G15 PLA2G1B PMP22 POTEJ PPAP2A PPAP2B PPAP2C PRX PSAP RAD21 RNASE2 SCAMP3 SCARB1 SCARB2 SCN4A SERPINA6 SGMS1

13 SGMS2 SGPP1 SGPP2 SIAE SLC35C1 SMPD2 SMPD3 SMPD4 SNORA29 SPTLC1 SPTLC2 STEAP2 STS SULT2B1 SYT1 SYT7 TCP1 TGM4 THBS2 THBS3 TPP1 TRIM46 TSHB UGCG UGT8 ABCD4 ACTBL2 ACTR2 ACTR3 ADAR ADPGK AFAP1 AIF1 ALG3 ALOX5 ALOX5AP ALPK2 AMICA1 ANXA6 AOAH AQP9 ARFGAP3 ARPC1A ARPC1Ap ARPC1B

14 ARPC4 ARPC4p ARPC5 ATG16L1 ATP13A3 ATXN2L BAIAP3 BANK1 BRP44 C11orf2 C1orf59 CAB39L CAPZB CCL3 CCL4 CD163 CD1C CDKAL1 CHMP2B CHPF CLEC4A CLEC4E CLEC7A CORO1A CTLA4 DACT1 DBN1 DGCR8 DICER1 DLG5 DQB1 DSP DZIP1L E2F3 E2F4 E2F5 ENTPD1 FAM49A FAM65B FCGR3A FGL2 FNDC4 FOSB FPR1 FZD1

15 FZD7 FZD8 GAS6 GBP5 GEMIN2 GEMIN4 GEMIN5 GIMAP1 GIMAP7 GIMAP8 GNAI1 GNAI2 GPR124 GPR125 GPR65 GZMA HENMT1 HMGA2 HS1BP3 IFT74 IGSF6 IL23A IL23R INPPL1 IQGAP1 IRAK3 IRGM ITLN1 ITPR2 LAMA2 LCA5 LCP1 LILRA2 LILRA6 LILRB2 LIMA1 LMX1A LOC LOC LRRK1 MECP2 MFHAS1 MNDA MPC2 MPEG1

16 MPRIP MS4A6A MS4A6E MS4A7 MUC19 MYCN MYL1 MYL9 MYO1A MYO1B MYO1C MYO1D MYO1E MYO1G MYO1H NCF1 NCF2 NFATC2 NKX2-3 NLRC4 NOD1 NSF P2RY13 PIWIL1 PLEC PLIN1 PLIN2 PLS1 PLS3 PPP1R12B PRR32 PSMD11 RAI1 RAI14 RBFOX1 RDX REM1 RGS18 RP4-695O20 B.10 S1PR4 SASH1 SAV1 SCYL3 SFRP1 SGK223

17 SIP1 SLC38A7 SLC7A7 SMARCA2 SNCG SOX1 TAGAP TAOK1 TARBP2 TFDP2 TLR1 TLR8 TMOD3 TMPRSS6 TNFSF13B TNPO1 TOPBP1 TP63 TPM1 TPM2 TPM3 TTF2 USP40 VANGL2 VNN2 VPS51 WNT7B ZFP36 ZNF362 ZNF365 ZNF384 haif ABC17 ABCG5 ABCG8 ABL1 ABL2 ACACA ACACB ACIN1 ACTA1 ACTL6A ACTL6B ADAM10

18 ADAM15 ADAM9 ADCY2 ADRB1 ADRB2 AGL AHR AICDA AIFM1 AIRE AK6 AKT2 ALK AMFR ANAPC1 ANAPC4 ANAPC5 ANAPC7 APBA2 APBB1 APLNR APOBEC2 APOBEC3B APOBEC3C APOBEC3D APOBEC3F APOBEC3G APOBEC3H APOBEC4 ARHGAP32 ARID1A ARIH1 ARL6 ARNT ARNT2 ARR3 ARRB1 ARRB2 ASB1 ASB11 ASB2 ASF1A ASTN2 ASXL1 ATF3

19 ATF6 ATM ATP1A2 ATP2A2 ATP2B1 ATP6 ATRIP ATRN AUP1 AURKA AURKB AXIN2 AZI2 BACH1 BAG2 BAG3 BAI3 BAK1 BARD1 BBC3 BBOX1 BBS10 BBS12 BBS4 BBS5 BBS7 BBS9 BCKDHB BCL10 BCL2 BCL2L11 BCL6 BCL6B BCL9L BCR BHLHE40 BIRC2 BIRC3 BIRC5 BMI1 BMP2 BMP4 BMPR1A BNIP3 BRAP

20 BRCA1 BRCA2 BRCC3 BRIP1 BRSK2 BST2 BTG3 BTK BUB1 BUB1B BUB3 C14orf153 C17orf70 C19orf40 C5orf4 CA12 CA9 CACYBP CAMK2A CAND1 CARD11 CARD17 CARM1 CASK CASP1 CASP7 CBLC CBLL1 CBX2 CCM2 CCNA1 CCNB1 CCNB1IP1 CCND2 CCND3 CCNE1 CCNF CCNO CCR2 CCR5 CD244 CD276 CD3E CD40 CD44

21 CD69 CD82 CD86 CDA CDC14A CDC16 CDC20 CDC23 CDC25A CDC25C CDC27 CDC42 CDC6 CDH1 CDH10 CDH2 CDH9 CDK1 CDK2 CDK6 CDK8 CDKN1A CDKN1B CDKN1C CDT1 CENPB CENPC CENPC1 CENPF CENPH CEP250 CFH CFLAR CHEK1 CHEK2 CHKA CHRNA1 CHRNA3 CHRNA5 CLOCK CLSPN CLUH CNOT1 CNOT4 CNR2

22 CNTN4 COBRA1 COL2A1 COMMD1 COMMD6 CORO2A COX11 CPLX2 CPXCR1 CREB1 CRK CRKL CROCC CRTC2 CRY1 CRY2 CRYZ CSF1R CSTF1 CTCF CTDSP1 CTDSPL CTGF CTRL CTTN CUL2 CUL4A CUL5 CUL7 CXCL12 CXCR4 CYLD CYP11A1 CYP19A1 CYP7A1 DAP DAPK1 DCTN1 DDB1 DDB2 DDIT4 DDX5 DDX53 DDX58 DET1

23 DHCR24 DHX9 DIO2 DIRC2 DKFZp313A2019 DKK1 DLG1 DLG3 DLG4 DLGAP2 DLK1 DLL1 DLL4 DNTT DPF1 DQ-A1 DTL DTX2 DTX3 DTX3L E4F1 ECE1 EDA2R EDN3 EDNRB EED EFNB1 EGF EGLN1 EGR3 EIF2AK3 EMD EML4 EP300 EPAS1 EPCAM EPHB2 EPHB3 EPM2A EPN1 EPOR ERBB3 ERBB4 ERN1 ERVW-1

24 ERVWE1 ESPL1 ESRRA ESRRB ESRRG ETS2 EXOC2 EZH2 FABP2 FAF2 FAM24A FANCA FANCB FANCC FANCD2 FANCE FANCF FANCG FANCI FANCL FANCM FAXDC2 FBP1 FBXL14 FBXL18 FBXL5 FBXO2 FBXO25 FBXO27 FBXO32 FBXO40 FBXO43 FBXO44 FBXO45 FBXO5 FBXO6 FBXW5 FBXW8 FEN1 FGF1 FGF2 FGF8 FGFR2 FH FKBP4

25 FLI1 FLT1 FLT3LG FOS FOSL1 FOXA1 FOXA2 FOXD3 FOXO3 FOXO4 FOXP2 FOXP3 FPR2 FRAT1 FRAT2 FZD4 GADD45A GGH GGNBP1 GHR GJA1 GLCE GLI2 GLMN GLTSCR2 GMNN GNA11 GNA15 GNAO1 GNAS GPR1 GPR81 GRB2 GRIA1 GRIK1 GRIK1-AS2 GRIN2B GRM8 GRP GSK3A GSTA1 GSTA2 GSTA3 GSTA4 GYS1

26 H3F3A H3F3B H3F3C HACE1 HCRT HCRTR1 HDAC10 HDAC3 HDAC9 HECW1 HECW2 HERC2 HERC5 HEY1 HEY2 HGF HIF1AN HIF3A HIPK2 HIST1H2BA HIST1H2BC HIST1H2BD HIST1H2BF HIST1H2BH HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H2BF HIST2H4A HIST2H4B HIST3H2BB HIST4H4 HIVEP1

27 HIVEP3 HK1 HK2 HLA-DPA1 HLA-DRB4 HLTF HM13 HMOX1 HNRNPUL1 HOMER1 HOXA5 HOXA9 HOXB4 HOXB7 HOXD9 HP HPR HUWE1 ICAM1 IDE IDH1 IDH2 IFIH1 IFIT1 IFNA17 IFNA2 IFNA21 IFNAR1 IFNAR2 IFNB1 IFNG IGBP1 IGF1R IGF2 IGF2BP1 IKBKB IKBKE IKBKG IL10 IL1R1 IL2RA ING4 INHBE INSIG1 INSIG2

28 IQCF6 IRAK1 IRAK4 IREB2 IRF3 IRF5 IRF7 IRF8 IRS1 IRS2 ISG15 ISG20 ITCH ITGA2B ITGAE ITSN1 JADE1 JAG1 JAG2 JAK1 JAK2 JUND JUP KAT2B KAT5 KAT8 KCNJ1 KCNJ11 KCNK1 KCNN4 KCNRG KDM5C KHDRBS1 KIF3A KIF5C KLC1 KLF10 KLF2 KLF4 KLF5 KLHL12 KLHL2 KLHL9 KLRG1 KRAS

29 KRT5 KXD1 LARGE LAT LATS2 LCP2 LEP LGALS3 LGALS4 LGI1 LIG4 LIMK1 LNX1 LOC LOC LOC LOC LOC LOC LOC LOX LPHN3 LRIG1 LRIG2 LRR1 LRRC41 LTN1 MALT1 MAP2 MAP2K4 MAP2K6 MAP2K7 MAP3K1 MAP3K3 MAP3K7 MAP4 MAPK14 MAPK6 MAPK9 MARCH3 MARCH4 MARCH5 MARCH6 MARCH8 MARCH9

30 MARVELD2 MAST1 MAST2 MAST3 MAVS MCM7 MCTS1 MDC1 MDM4 MECOM MED12 MEFV MET MGRN1 MIB1 MIB2 MIR4738 MIR6751 MIS12 MKRN1 MLH1 MLH3 MLXIPL MME MRE11A MSH2 MSH3 MSH6 MSI2 MSTN MT-ATP6 MT3 MTBP MTM1 MUTYH MYCBP2 MYD88 MYH11 MYL12A MYLIP MYOD1 MYST1 NAA50 NAIP NBN

31 NBPF10 NCL NDFIP2 NEDD4L NEK2 NELFB NEURL1B NEURL2 NEUROD1 NEUROD2 NF1 NF2 NFYA NGB NHLRC1 NKX2-1 NLGN1 NLGN3 NLGN4X NOL3 NOTCH2 NOTCH2NL NPLOC4 NPTX2 NR1H2 NR1H3 NR1H4 NR2F1 NR2F2 NR6A1 NRAS NRXN1 NTM NTRK1 NUMB NUMBL NUP98 OBSL1 OGDH OLR1 OPCML OS9 OTUB1 OTUD5 OXSR1

32 P4HTM PARP1 PAX3 PAX4 PCGF2 PDCD2 PDCD4 PDGFB PDGFRA PELI1 PGR PHC1 PHC2 PHF10 PHF17 PHGDH PIAS1 PIAS4 PIK3CG PIN1 PJA1 PJA2 PKD1 PKD1P6 PKN1 PLA2G2A PLCG1 PLK1 PLK2 PLK4 PML PMS1 PMS2 POU5F1B POU5F1p PPID PPIL5 PPIP5K1 PPM1D PPP2R4 PPT1 PRC1 PRDM14 PRLR PRMT1

33 PROS1 PRR15 PRR30 PTCH1 PTHLH PTPN1 PTPN11 PTPN12 PTPN3 PTTG1 PXN PYCR1 QKI RABEP1 RABGGTA RAD18 RAD23A RAD50 RAD51 RALB RANGAP1 RAP1A RARA RARB RBBP8 RBPJ RC3H1 RCC1 RCHY1 RCOR1 REL RELB RERE RFPL4A RFWD2 RFWD3 RGS2 RHEB RHO RIPK1 RIPK2 RIPK3 RLIM RNF11 RNF115

34 RNF125 RNF128 RNF139 RNF148 RNF151 RNF160 RNF167 RNF168 RNF181 RNF182 RNF19A RNF2 RNF4 RNF41 RNF43 RNF6 RNF7 RNF8 ROCK1 RPGRIP1 RPS6KA1 RPS6KB1 RRAS2 RUNX1 RUNX2 RUVBL2 S100A1 S100A4 S1PR2 SAE1 SAG SAMHD1 SCN2A SCNN1A SCNN1B SCNN1G SCO2 SEL1L SENP1 SENP5 SEPT7 SERPINE1 SERPINI2 SETD8 SGK1

35 SH2D3A SH3RF1 SHC1 SHC2 SHH SIM2 SKI SKP2 SLC11A2 SLC12A3 SLC16A3 SLC16A4 SLC17A8 SLC22A18 SLC9A3R1 SLC9A3R2 SMAD2 SMAD5 SMAD6 SMAD7 SMO SMUG1 SMURF1 SMURF2 SMYD2 SNAI1 SNX9 SOAT1 SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SOD3 SOX9 SP1 SP100 SPHK1 SPO11 SPON2 SPOP SPP1 SPRY1 SPRY2

36 SPSB1 SPSB4 SRRM1 SSBP2 SSRP1 SST ST13 STAM STAM2 STAMBP STAP2 STAT1 STAT2 STAT3 STK11 STMN2 SUZ12 SYNGAP1 SYT2 SYVN1 T TADA2A TADA3 TAF1 TAF1L TAF9 TANK TAP1 TAS2R1 TBK1 TBX2 TCEB2 TCEB3 TCF4 TCF7 TCF7L2 TDG TERT TET2 TFCP2 TGFA TGFB2 TGFBR2 TGFBR3 THADA

37 THBS1 THPO TIAF1 TIAM1 TICAM1 TIFA TIMELESS TIMM44 TJP1 TLE2 TLE6 TLR3 TLR7 TLR9 TMEM185A TMEM189 TMEM189-UBE2V1 TNFAIP3 TNFRSF10B TNFRSF1A TNFRSF1B TNFSF10 TNFSF14 TNKS TP53AIP1 TP53BP1 TP53INP1 TPX2 TRADD TRAF1 TRAF3 TRAF5 TRAF7 TRIB1 TRIB2 TRIB3 TRIM11 TRIM13 TRIM17 TRIM21 TRIM24 TRIM25 TRIM32 TRIM34 TRIM5

38 TRIM50 TRIM63 TRIM68 TRIP13 TRPV4 TSC1 TSC2 TTN TUBA4A TUBB2A TUBG1 TYK2 TYRO3 UBA1 UBASH3A UBASH3B UBE2A UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2T UBE2V1 UBE3A UBE3B UBP1 UBR1 UBR5 UCP3 UHRF1 UIMC1 UNG USP1 USP14 USP15 USP2 USP20 USP25 USP30 USP44

39 USP6 USP7 USP8 VAV1 VCL VHL WARS WEE1 WNK1 WNK2 WNK3 WNK4 WNT16 WNT3A WSB1 WT1 WWP1 WWP2 XAF1 XIAP XPA XPC XRCC6 YAP1 YEATS4 YIPF1 YY1 ZFAND2A ZFAND2B ZFYVE9 ZHX2 ZKSCAN7 ZNF135 ZNF167 ZNF346 ZNF350 ZNF436 ZNF44 ZNF501 ZNF569 ZNF615 ZNF629 ZNF645 ZNF763 ZNRF4

40 hmdc1 ACADM ACAT1 ACTR10 ADSL AHSA1 AIMP1 AK2 AKR1A1 AKR7A2 ALDH7A1 ALG8 ANAPC13 ANP32A ANP32B ANXA1 ANXA2 ANXA5 AP2S1 APEX1 APOA1BP APRT ARL6IP4 ARPC3 ATIC ATOX1 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5EP2 ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5O ATP6V0B ATP6V0E1 ATP6V1E1 ATP6V1F

41 ATP6V1G1 ATPIF1 ATRAID AURKAIP1 BBS1 BCCIP BCS1L BOLA3 BTBD12 BZW2 C10orf85 C11orf10 C11orf31 C11orf48 C11orf58 C11orf73 C12orf10 C12orf62 C14orf156 C14orf166 C14orf2 C15orf24 C16orf61 C16orf80 C17orf37 C17orf61 C17orf79 C19orf10 C19orf20 C19orf43 C19orf53 C19orf56 C19orf70 C1orf116 C1orf123 C1orf151 C1orf174 C20orf24 C21orf33 C21orf57 C22orf28 C22orf32 C2orf15 C2orf28 C2orf79

42 C6orf125 C6orf14 C6orf203 C7orf55 C8orf40 C9orf123 CALCRL CAMTA1 CCDC53 CCDC56 CCT2 CCT3 CCT4 CCT5 CCT7 CD63 CDC123 CDIPT CFAP20 CFL1 CHCHD1 CHCHD2 CHD2 CHD4 CHD7 CHMP2A CIB1 CISD1 CKS1B CLCF1 CLNS1A CMC2 CNBP COA3 COA4 COL1A1 COL1A2 COMMD3 COMMD8 COPRS COPS3 COPS6 COPZ1 COQ5 COX14

43 COX16 COX17 COX4I1 COX5A COX5B COX6A1 COX6A1P2 COX6B1 COX6C COX7A2 COX7A2L COX7B COX7C COX8A CPEB1 CRP CSDE1 CUEDC2 CUTA CWC15 CYC1 DAD1 DCAF11 DCTN3 DCTPP1 DDCT DDOST DDT DDX47 DNAJC15 DNPEP DPM1 DPP3 DRAP1 DRG1 DYNLL1 DYNLRB1 DYNLT1 EBNA1BP2 ECHS1 EDC3 EDF1 EEF1A1 EEF1B2 EEF2

44 EIF1 EIF2A EIF2B1 EIF2B2 EIF3D EIF3G EIF3H EIF3I EIF3K EIF3L EIF3M EIF4A3 EIF4H EIF5A EIF5A2 EIF6 ELMO1 EMC4 EMC6 EMC7 ENO1 ENOPH1 ENY2 ERAL1 ERH ERP29 ETFB EXOSC7 FAM136A FAM32A FAM96A FAU FBXO17 FIBP FKBP14 FKBP2 FKBP3 FNTA FUBP1 GALK1 GATAD2B GCSH GGCT GHSR GLRX3

45 GNE GNL3 GNPAT GORASP2 GPN1 GPR157 GPS1 GPX4 GRHPR GRPEL1 GSTP1 GTF2A2 GTF2E2 GTF3A H2AFV H2AFZ HADH HADHB HARS HBXIP HIGD2A HIGD2B HINT1 HINT2 HMBS HNRNPR HSBP1 HSD17B10 HSPB11 HSPD1 HSPE1 IARS2 ICT1 IDH3B IDH3G IK ILF2 IMMT IMP3 IMPDH2 ISCU ITPA JTB KCNAB2 KNCN

46 KRTCAP2 LAGE3 LAMTOR2 LAMTOR4 LAMTOR5 LCMT1 LDHB LIN37 LIN54 LOC LOC LOC LOC LOC LOC LOC LOC LOC LOC LOC LOC LRRC47 LSM1 LSM10 LSM3 LSM4 LSM5 LSM7 LSMD1 MANF MAP2K2 MBD3 MDH1 MDH2 MEA1 MEX3B MIEN1 MIF MINOS1 MIR3934 MIR6733 MIR6890 MIR7113 MRFAP1 MRPL1

47 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL32 MRPL33 MRPL34 MRPL37 MRPL40 MRPL43 MRPL46 MRPL48 MRPL51 MRPL53 MRPL54 MRPL9 MRPS10 MRPS11 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS21 MRPS23 MRPS24 MRPS25 MRPS28 MRPS33 MRPS34 MRPS35 MRPS7

48 MRPS9 MTA1 MTCH2 MTIF2 MTRF1 MZT2A MZT2B NAA20 NAA38 NACA NCBP2 NDUFA11 NDUFA12 NDUFA13 NDUFA2 NDUFA3 NDUFA4 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFAB1 NDUFAF1 NDUFAF3 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC1p NDUFC2 NDUFS2 NDUFS4 NDUFS5 NDUFS6 NDUFS8 NDUFV1 NDUFV2 NFU1 NGRN

49 NHP2 NHP2L1 NIF3L1 NIT2 NME1-NME2 NME2 NOL7 NOP10 NSA2 NSMCE1 NUDC NUP37 OAZ1 OR4K5 OR4L1 OTUD7B P14 PAICS PAIP2 PCBP1 PDCD5 PDCL3 PDIA6 PDPK1 PEBP1 PER3 PFDN1 PFDN2 PFDN5 PGAM1 PHB PHB2 PHF5A PHPT1 PLAG1 PLAT PMPCB POLR2A POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3

50 POLR2L POMP POP5 PPA1 PPCDC PPCS PPIB PPP1CA PPP1CC PPP2R1B PRDX1 PRDX2 PRDX3 PRDX4 PRDX5 PRDX6 PRICKLE4 PSENEN PSMA2 PSMA5 PSMA6 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB7 PSMC1 PSMC2 PSMC4 PSMD13 PSMD3 PSMD8 PSME1 PSME2 PSMG1 PSMG2 PTRHD1 PWP1 QARS QDPR RABGGTB RALGAPA1

51 RAN RER1 RHBDL2 ROBLD3 ROMO1 RPA2 RPA3 RPL10A RPL12 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL22 RPL23 RPL24 RPL26 RPL26L1 RPL27 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36AL RPL37A RPL38 RPL4 RPL41 RPL6 RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPN1 RPN2 RPS10 RPS11

52 RPS12 RPS13 RPS14 RPS15A RPS16 RPS17 RPS19 RPS19BP1 RPS20 RPS21 RPS23 RPS24 RPS25 RPS27 RPS27L RPS29 RPS3 RPS3A RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RSL24D1 RTCB RUVBL1 SAMM50 SAR1A SAR1B SARS2 SDHC SEC11A SEC13 SEC61B SEC61G SELO SERBP1 SET SF3A3 SF3B5 SF3B6 SHFM1 SLC25A3 SLC25A5

53 SLC25A6 SLC30A9 SLIRP SLX4 SMDT1 SMIM19 SNF8 SNORA21 SNORA52 SNORA62 SNORD14B SNORD18A SNORD34 SNORD35B SNORD38B SNORD54 SNORD83B SNRNP25 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SPAG7 SPCS1 SPCS2 SPPL2C SRP14 SRP19 SRP9 SRSF3 SRSF9 SS18L2 SSB SSR2 SSR4 STMN1 STOML2 STRA13 TAF3 TBCA TBCB

54 TCF3 TECR THEMIS THOC7 THRA THUMPD1 TIMM10 TIMM13 TIMM17A TIMM8B TIMM9 TK1 TMA7 TMCO1 TMEM126A TMEM126B TMEM147 TMEM14B TMEM14C TMEM208 TMEM256 TMEM258 TMEM261 TMEM85 TMEM93 TMSB10 TMX2 TOMM7 TOP2B TPGS1 TPI1 TPRKB TPT1 TRAPPC2L TRAPPC3 TREH TRIAP1 TRIP12 TRMT112 TRMU TRPM7 TTC1 TUBA1B TUFM TXN2

55 TXNDC17 UBL5 UBXN1 UCHL3 UCKL1 UFC1 UFD1L UFSP2 UPK3BL UPRT UQCR10 UQCR11 UQCRB UQCRC1 UQCRFS1 UQCRH UQCRQ UROD USMG5 USP19 VAMP8 VDAC3 WDR61 WDR83OS YBEY YIF1A ZBTB8OS ZCCHC17 ZNHIT1 ZNHIT3 ABTB1 ADCK3 AFG3L2 ANKRD20A1 ATG4A ATG9A C17orf47 C2orf24 CABC1 CALCOCO1 CBX7 CNPPD1 COX1 COX6B2 DNAJB2

56 DUSP6 FABP4 FAM134A FAM214B FBXO9 FKBP8 GABARAP GDAP1 HAGH HYAL3 IMPG1 IRS4 KAL1 KIAA1539 KIF11 LOC LRP10 MGAT1 MGLL MIPEP MIR1909 MIR4746 MT-CO1 MT-ND1 MT-ND4 MT-ND4L MT-ND6 MTFP1 NCAM1 NCAM2 ND1 ND4 ND4L ND6 NDRG2 NPS ODC1 OTX2 PARL PDK2 PGAM5 PITX2 PLEKHA6 PLEKHG1 PRPF4B

57 RAB33B RB1CC1 REXO1 RHOT2 RICTOR SH3GLB1 SLC35D1 S4 STK4 TCP11L2 TIGD3 TIMM23B TPRG1 TPRG1L TRAPPC12 TTC15 TUBB TYMP UBXN6 WBP2 YIPF3 YPEL3 ZER1 ABCC2 ABHD4 ADAM23 ADAP2 ADH4 ADH6 ADH7 ADI1 AHSG AHSP ALAS2 ALDH2 AMBP ANKK1 AP1B1 APCS APOA1 APOA4 ARAF ARHGAP15 ASGR1 ATOH1

58 ATXN7 AUTS2 B2M B3GAT1 BACE2 BAD BCHE BLK BLVRB BPGM C10orf2 C17orf97 C19orf22 C3orf14 CA1 CA14 CA2 CADPS2 CALCA CAPN1 CAPN2 CAPNS1 CBX4 CCDC25 CDC42EP2 CDC42EP3 CDC42SE1 CERS3 CHAT CHRM2 CLTA COX3 CPS1 CRHR1 CRHR1p CSNK1D CST3 DCAF12 DNAJC5 DOB DOCK11 DOPEY2 DPPA4 DSCAM DSCR8

59 EFHA1 EFHA2 ELK1 EPB42 ERG F2 FECH FGA FGF16 GABARAPL1 GABRA2 GABRA6 GABRG3 GAL GATA2 GDA GLRX5 GMPR GPRIN3 GRK1 GRK5 GRK6 GRM1 GRM5 GSN GTSF1 GULP1 GYPA HBB HBD HBE1 HBG1 HBG2 HBM HBQ1 HBZ HCK HEMGN HIST1H1C HLA-DOB HOOK2 HOXB6 HSPG2 IAPP IARS

60 IGHG1 IGKV4-1 ISY1 ITGB3 ITGB7 ITM2B KANSL1 KCNAB1 KIAA1191 KIAA1267 KLF1 LAMA1 LASS3 LIN28A LOC LOC LOC LRP1B LTF MAL MAOA MAP1LC3A MAPK3 MAPK8IP1 MARK1 MEF2D MFGE8 MICU2 MICU3 MLANA MMRN1 MPP1 MT-CO3 NFE2 NPPA NPTX1 NRG3 NRXN3 NTS ODAM OPRK1 OR2W3 OSBP2 PAFAH1B2 PAK3

61 PICALM PIGB PITHD1 PLA2G4A PLCB2 PLD1 PPP2R5D PRKCA PRKCB PRKCD PRKCG PRL PRSS53 PTK2B R3HDM4 RAB39B RAD23B RAF1 RCAN1 REST RHAG RHCE RHOXF2 RTN4RL2 RUNDC3A SELENBP1 SEMG1 SESN3 SILV SLC16A12 SLC25A37 SLC25A41 SLC4A1 SLC6A15 SLC6A4 SP3 SPTA1 SPTBN1 ST3GAL6 STRADB TACR1 TAS2R16 TAS2R38 TECTB THY1

62 TMCC2 TMEM106B TMOD1 TOP2A TPPP TRAM1L1 TRDN TRIM58 TSPAN5 TTR TUBA3C TUBA3D TUBA3E TYRP1 UTS2 WDFY3 WNT3 XK YES1 YWHAE ZNF219 ZNF30 ZNF345 ZNF582 ZSCAN A2RRL4 A8MZ06 ABCE1 ACTR6 AHCYL1 AMPH ANKRD27 ANKRD40 ANXA7 AP3M1 AP3M2 API5 ARFGEF1 ARFGEF2 ARFIP1 ARFRP1 ARL10 ARL16 ARL8B

63 ATAD1 ATG14 ATG2B ATG9B ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0D1 ATP6V0D2 ATP6V1C1 ATP6V1D BCAP29 BDP1 BET1 BZW1 C16orf63 C16orf87 C20orf20 C2orf63 CALR3 CAPRIN1 CCDC132 CCT6A CCT8 CETN3 CHCHD4 CHMP4B CHMP6 CLINT1 CLTCL1 COG6 COG8 COPA COPB1 COPG COPG1 COPS2 CPD CPSF3L CWC27 CWH43 CYB5B CYBB CYTH1 DARS

64 DCAF13 DLD DPH7 DSCR3 DUOX2 EHD1 EIF2S2 EIF3E EIF4G2 ELP4 EMC2 EPRS ERGIC2 ESF1 EXOC3 EXOC5 EXOC6 FAM21C FAM91A1 FBXL12 FKBP15 FOPNL GABARAPL2 GAPVD1 GCDH GGA1 GOLGA1 GOLGA2 GOLPH3 GOSR2 GPBP1 GRTP1 HIP1 HOOK1 HSPE1-MOB4 IPO4 IRF4 ITFG1 KCNA4 KCTD7 KIAA0196 KIAA0368 KIAA1033 KIAA1432

65 KIAA1826 KIF16B KLHL7 LAMTOR3 LARS LOC LOC LOC LUZP6 MAPKSP1 MIR6836 MITD1 MMS19 MOBKL3 MON2 MORF4L2 MRGBP MSANTD4 MSRB2 MTMR6 MTNR1B NAA15 NAA30 NAA35 NADSYN1 NARS NCKAP1 NCKAP1L NIPSNAP3A NIT1 NMUR2 NOX3 NOX5 NUDT21 ORC4 ORC4L OSTF1 PACS1 PAPOLA PDCD10 PEX10 PEX12 PGM2 PHKB PIGR

66 PIK3C3 PIK3R4 PIKFYVE PLIN3 PLRG1 PNO1 POLR2B PSMD6 PSMD7 RAB10 RAB11A RAB18 RAB34 RAB36 RAB41 RAB6A RAB6C RAB7A RAB9B RABGEF1 RBM16 RGS14 RIC1 RPAP2 RSBN1L RYK SCAF4 SCAF8 SCAMP1 SCOC SCYL2 SEC31A SEC31B SEP15 SERPINE2 SFRS15 SLC25A46 SMU1 SNX10 SNX11 SNX12 SNX14 SNX15 SNX16 SNX17

67 SNX18 SNX27 SNX3 SNX30 SNX32 SNX33 SNX4 SNX5 SNX6 SNX7 SNX8 SORCS1 SORCS2 SORCS3 SORT1 SPCS3 SRP72 STAG2 STRAP STX16 STX17 SUGT1 SUPT5H SYNJ1 SYS1 TBC1D15 TBC1D5 TCIRG1 TGFBRAP1 THUMPD3 TMED2 TMX1 TOP1MT TPD52L2 TRAPPC6A TRAPPC6B TRMT12 TRMT5 TSNARE1 TTC35 UBA3 UBLCP1 USO1 USP10 USP32

68 USP43 USP9Y UVRAG VAC14 VPS13A VPS13B VPS13C VPS13D VPS16 VPS18 VPS25 VPS26A VPS26B VPS36 VPS37D VPS39 VPS41 VPS4B VPS52 VPS53 VPS54 VPS8 VTA1 WASH WASH1 WDR85 WLS WTH3DI XRN2 YARS2 YME1L1 YWHAZ ZACN ZNF638 ZNF638-IT1 hvps52 CTSD KL DNAJC6 MYO1F PPP1R12A RAB5B CD1B CTSS IL1B

69 PAH RNASEH2A TMEM163 BIRC6 FLJ54303 HERC3 HSPA1Ap HSPA2 LOC ABCA1 ABHD14A ACKR1 ASPSCR1 CANX CBL DARC DDIT3 EPO FLT3 GAMT HLA-A HLA-B IL3 INSR KITLG KLK3 NR3C1 SMPD1 TFAP2A XBP1 AGO2 ANK1 APAF1 ARHGEF7 ATF4 ATXN1 AXIN1 CASP8 CCND1 CD83 CDKN2A CISH COL3A1 CTDSP2 DDX19B

70 DMBT1 DROSHA E2F1 EIF2C2 EIF4E EZR FMR1 GFER HDAC6 HECTD2 HLA DQB1 KIAA1804 LACC1 LOC LRP6 LTA4H MARCH1 MDM2 MLK4 MRAP MSN MTOR MYC NFKBIA NOBOX NOD2 NOS2 OPA1 P4HA1 PDYN PIK3CA PLEK PTPRC RAC1 RAC3 RACGAP1 RB1 RBCK1 RELA RNASEN SIRT1 SLC11A1 SMAD3 SMAD4 SMARCA4

71 SPRYD7 STAT5B TAB1 TGFB1 TLR2 TLR4 TNFSF15 TNP1 TP73 TRAF2 TRIM22 TRIM71 USH2A VIL1 VPRBP ZNF746 CNIH CNIH1 DNAJC8 MAGOH MRPL3 SARNP SNRPC STX8 ACE COPS4 ETFA FAM96B FTL PDIA3 PKLR PKM PKM2 ARPC2 ATP5L DDX20 EFHD1 EFHD2 GEMIN6 MYL12B MYL6 PPP2R1A SDHD ANAPC11 BABAM1

72 BAG1 BANF1 C19orf62 CDK4 CLPP CNPY2 CTSB DERL2 DIABLO EMG1 ESR1 FADD FN1 GNB2L1 GOT2 GTF2B HDAC1 IGFBP3 LDHA LOC LTBR MMP9 MPO MTA2 NEDD8 NGFR NME1 NOTCH1 NPM1 PCNA PPIA PSMA1 PSMA3 PSMC3 PSMC5 PSMD4 RBBP4 RBBP7 RBX1 RNASE1 RPL11 RPL5 S100B SDHB SFN

73 SNORD95 SREBF1 SREBF2 SUCLG1 SUMO1 SUMO3 TCEB1 TIMP1 TNFRSF10A TOMM5 TOPORS TXN UBE2V2 WDFY2 APPL1 MTIF3 TFAM ZNF785 AMBRA1 CDC34 CKAP2 FOXO1 MARCH2 PRKDC RHOT1 RNF123 RNF31 CS EFCAB6 FIS1 GPX1 HAX1 LOC MRPL36 NDUFA9 NDUFS3 NDUFS7 PSMD1 SEMA6A TIMM23 UXT SNAP25 STX1A STX1B AGA

74 APOA2 CKAP5 LYZ PANK2 SKAP2 TGM1 ATG5 CHM DRD2 FGF20 FGR GRN RAB29 RAB7L1 RBBP9 SPR TARDBP TOR1A ADRBK1 AFP APC BTRC CAPN3 CASR CAST CDK5 COL25A1 CREBBP CSNK2A1 CSNK2A2 CTNNB1 DCT DERL1 DNAJA1 DNMT3B EGLN2 EGLN3 F11R FASLG FST FYN GATA4 GRB10 HAVCR2 HIF1A

75 HNF4A JAM3 KHDRBS3 KLK6 LCK LEF1 LIG3 LOC LYN MAP2K1 MAPK1 MAPK8 NANOG NEDD4 NEUROD6 NPY OPRD1 PICK1 PLD2 POLB POU5F1 PRKCE PTGS2 QPCT RNF5 RNF5p RP11-544M22.13 SEPT2 SEPT4 SIAH1 SIAH2 SOX2 SRC SYK SYN1 SYP TGM2 TLN1 UBE2J1 UBE2L6 XRCC1 YWHAH ADH5 ENO2 HSPB1

76 IGFBP1 LRP8 NDUFB11 NDUFB6 PSMB6 RABAC1 UQCRC2 VLDLR C20orf108 DMTN EPB49 FAM210B MAP1LC3B RNF10 SORBS3 TK2 ATP2C1 C4orf41 COPB2 DHX15 DNAJA2 OFCC1 PRRT2 RAB5A SEC23IP SERINC1 SLC35A5 SNX1 SNX2 STX10 STX12 STX7 TMEM30A TRAPPC11 VPS29 VPS33A VPS45 XRN1 YKT6 ZNF148 CTSA LAMP2 M6PR MTMR2 ATG7

77 CAB39 CAPZA1 CAPZA2 CSE1L GNAI3 CRBN CUL3 CUL4B EIF4G1 ELAVL1 H2AFX HGS KIF5B MED21 MUL1 PGAP2 PI3 RNF103-CHMP3 RNF20 STX5 TAX1BP1 TBCE TCEA1 TFRC TGOLN2 TNKS2 TSG101 VEGFA VPS24 VPS4A XPO1 ZBP1 ARL1 CHMP4A CHMP5 CPSF3 DDX1 DPY30 DYNC1I2 GDI2 GHITM MMADHC NAE1 PCMT1 PDHB

78 PIGY PYURF TALDO1 VPS28 VTI1B ATG12 ULK1 WIPI1 WIPI2 CLTC FURIN RAB6B USP9X ZC3H14

devseek (Sequence(Analysis(Panel(for(Neurodevelopmental(Disorders

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