January 16-19, Sheraton Steamboat Hotel Steamboat Springs, Colorado

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1 The University of Texas MD Anderson Cancer Center Advances and Controversies January 16-19, 2015 Sheraton Steamboat Hotel Steamboat Springs, Colorado

2 EDUCATIONAL METHODS Lectures - Question and Answer Sessions Case Presentations Meet the Sessions EVALUATION Advances and Controversies January 16-19, 2015 A course evaluation form will provide participants with the opportunity to comment on the value of the program content to their practice decisions, performance improvement activities, or possible impact on patient health status. Participants will also have the opportunity to comment on any perceived commercial bias in the presentations as well as to identify future educational topics. ACCREDITATION/CREDIT DESIGNATION The University of Texas MD Anderson Cancer Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Texas MD Anderson Cancer Center designates this live activity for a maximum of AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Sheraton Steamboat Hotel Steamboat Springs, Colorado ETHICS CREDITS GOAL The goal of this program is to provide up-to-date information to the practicing physician regarding new advances in cancer care and treatment. CME CERTIFICATES AND ATTENDANCE VERIFICATION CERTIFICATES EDUCATIONAL OBJECTIVES After attending the conference, participants should be able to Interpret information and incorporate into treatment the novel therapies for solid tumors including Breast Cancer, Lung Cancer, Colorectal Cancer, Genitourinary Cancer, Melanoma, and Sarcoma (Knowledge, Competence, Performance, Patient Outcomes) Utilize different surgical, radiation, and systemic treatments including molecularly targeted therapies for these cancers at various stages of disease (Knowledge, Competence, Performance, Patient Outcomes) Incorporate appropriate sequence for surgical, radiation, and chemotherapeutic intervention for patients (Knowledge, Competence, Performance, Patient Outcomes) Illustrate and implement the optimal treatment approach when given patient scenarios representing a range of stages, prognostic markers, and clinical presentations (Knowledge, Competence, Performance, Patient Outcomes) Interpret the clinical effectiveness of the different treatment modalities based upon efficacy and toxicity parameters (Knowledge, Competence, Performance, Patient Outcomes) TARGET AUDIENCE This program will be of interest to surgical oncologists, medical oncologists, radiation oncologists, diagnostic radiologists, pathologists, resident trainees, primary care physicians, advanced care practitioners, physician assistants, and nurses involved in oncologic care. Session VI presentations have been designated by The University of Texas MD Anderson Cancer Center for a total of 3.25 AMA PRA Category 1 CreditsTM in medical ethics and/or professional responsibility. Certificates awarding AMA PRA Category 1 CreditTM or certificates documenting attendance will be distributed to participants when an individual departs the conference. To obtain a CME certificate, physicians must submit a completed evaluation questionnaire and a CME Verification Form. Upon request, a record of attendance (certificate) will be provided on-site to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations. CONFERENCE CHAIRMAN Merrick I. Ross, MD, MD Anderson MD ANDERSON ORGANIZING COMMITTEE Rae Brana Reynolds, RN, MSN Manager, Mid-Level Provider, Cynthia A. Scott Office Manager, Constance Tierney, CMP Manager, CME/Conference Management

3 Program The conference will begin with registration from 3:00-5:00 p.m. on Friday, January 16, 2015 followed by a session from 5:00-8:30 p.m. and a Welcome Reception from 8:30-10:00 p.m. All other sessions will run from 7:00 a.m.-1:00 p.m. and 4:30-8:00 p.m. on January 17 & 18, 2015, and from 7:00 a.m.-1:00 p.m. on January 19, Friday, January 16, :00 5:00 p.m. Registration Session I Breast Cancer Moderator: Kelly K. Hunt, MD 5:00 p.m. The Art and Science of Genetic Counseling in Breast Cancer Jennifer Litton, MD New Paradigms in the Surgical Management of the Regional Lymph Nodes in Breast Cancer Kelly K. Hunt, MD Selective Use of Adjuvant Therapy: Have the New Markers Helped? Funda Meric-Bernstam, MD Update on Triple Negative and Inflammatory Breast Cancer Jennifer Litton, MD Recurrent HER-2 Breast Cancer: Beyond Trastuzumab Vicente Valero, MD Update on Post-Mastectomy Radiation: Are the Indications Evolving? Thomas A. Buchholz, MD Reconstruction Options in Patients Who Have Received Post-Mastectomy Radiation Melissa A. Crosby, MD Keynote Presentation Cancer Vaccines: Breast Cancer and Beyond Elizabeth A. Mittendorf, MD 8:30-10:00 p.m. Welcome Reception Saturday, January 17, :30 a.m. Registration/Continental Breakfast Session II Melanoma Moderator: Merrick I. Ross, MD 7:00 The Cancer Genome Project for Melanoma: What Have We Learned? Jeffrey E. Gershenwald, MD Noon Prognostic Factors Linked to Adjuvant Therapy: Any New Paradigms? Merrick I. Ross, MD Treatment of Stage IV Disease: The Art and Science of Decision-Making Patrick Hwu, MD Oncolytic Immunotherapy: Real Systemic Impact Or Just Another Intra-Lesional Therapy? Robert H. Andtbacka, MD Reconstruction After Definitive Surgical Treatment David M. Adelman, MD ; Victor G. Prieto, MD, PhD; Aysegul Sahin, MD Meet the Melanoma Surgical and Medical Oncologists 1:00 p.m. Session Adjourns Session III GI Cancer Moderator: Robert A. Wolff, MD 4:30 p.m. Systemic Therapy for Pancreas Cancer: Neo-Adjuvant or Adjuvant? Robert A. Wolff, MD Xenograft Models in Pancreas Cancer: Impact on Future Therapies Jason B. Fleming, MD Controversies in the Multimodality Management of Gastric Cancer Keith F. Fournier, MD Advances in Colorectal Surgery: Perspectives on Open vs Laparoscopic vs Robotic Surgery Y. Nancy You, MD Radiation Therapy for Rectal Cancer: Routine or Selective Use? Christopher Crane, MD Resection of Colorectal Liver Metastases: Still the Standard of Care? Steven A. Curley, MD 8:00 p.m. Session Adjourns

4 Sunday, January 18, :30 a.m. Registration/Continental Breakfast Session IV Moderator: Christopher G. Wood, MD 7:00 a.m. Debate 1: What is the Best Way to Perform a Radical Cystectomy for Muscle Invasive Bladder Cancer: Open Surgery - Jay B. Shah, MD Robotic Surgery - Neema Navai, MD Noon Robotic RPLND for Stage 1 High Risk Testis Cancer: Fad, Folly, or Standard of Care? Brian F. Chapin, MD Debate 2: What is the Most Appropriate Treatment for Stage T1b/T2 Renal Cell Carcinoma? Radical Nephrectomy - Christopher G. Wood, MD Partial Nephrectomy - Jose A. Karam, MD What is the Role of Control of the Primary Tumor in Metastatic Prostate Cancer? Brian F. Chapin, MD Proton Therapy for Prostate Cancer: Expensive Gimmick or Real Benefit? Andrew K. Lee, MD Meet the Session Adjourns Session V Thoracic Oncology Moderator: Stephen G. Swisher, MD 4:30 p.m. Current Recommendations for Lung Cancer Screening: Are We Making Any Progress? Stephen G. Swisher, MD Treatment of Primary Lung Cancer: Surgery or Stereotactic Radiation David C. Rice, MD; Quynh N. Nguyen, MD The Evolving Landscape of Systemic Therapy for Advanced Non-Small Cell Lung Cancer: The Impact of Molecular Analysis and the Emergence of Anti-PD-1 Therapy John V. Heymach, MD Multimodality Therapy for Advanced Esophageal Cancer Wayne L. Hofstetter, MD Update on the Role for Endobronchial Ultrasound in the Management of Lung Cancer David C. Rice, MD Monday, January 19, :30 a.m. Registration/Continental Breakfast Session VI Ethics Moderator: Merrick I. Ross, MD 7:00 a.m. Outcome Parameters in Cancer Care Karl Y. Bilimoria, MD Surgical Management of Lymphedema Edward I. Chang, MD Palliative Surgery: How Do We Measure Success? Brian D. Badgwell, MD Session VII HPV Symposium Moderator: Michael E. Kupferman, MD 10:30 The HPV Moon Shot: Grouping Cancers by Etiology Rather Than Anatomy Erich M. Sturgis, MD Robotic Surgery for HPV Head and Neck Cancer Michael E. Kupferman, MD Cervical Cancer Prevention Kathleen M. Schmeler, MD Keynote Presentation Surgery or Gamma Knife for Brain Metastases Jeffrey S. Weinberg, MD Session VIII Peritoneal Malignancies Moderator: Michael Frumovitz, MD Noon Multimodality Treatment for Ovarian Cancer Michael Frumovitz, MD Is There a Benefit for HIPEC in the Management of Peritoneal Carcinomas? Keith F. Fournier, MD 1:00 p.m. Session Adjourns 7:30 p.m. Session Adjourns

5 MD Anderson Faculty David M. Adelman, MD Assistant Plastic Surgery Brian D. Badgwell, MD Assistant Thomas A. Buchholz, MD EVP & Physician-in-Chief EVP Physician-in-Chief Edward I. Chang, MD Assistant Plastic Surgery Brian F. Chapin, MD Assistant Christopher Crane, MD Radiation Oncology Melissa A. Crosby, MD Associate Plastic Surgery Jason B. Fleming, MD Keith F. Fournier, MD Assistant Michael Frumovitz, MD Associate Gynecologic Oncology & Reproductive Medicine Jeffrey E. Gershenwald, MD John V. Heymach, MD Chair & Associate Thoracic/Head & Neck Medical Oncology Wayne L. Hofstetter, MD Associate Thoracic & Cardiovascular Surgery Kelly K. Hunt, MD Patrick Hwu, MD Melanoma Medical Oncology Jose A. Karam, MD Assistant Michael E. Kupferman, MD Associate Head & Neck Surgery Andrew K. Lee, MD Radiation Oncology Jennifer Litton, MD Assistant Breast Medical Oncology Funda Meric-Bernstam, MD Elizabeth A. Mittendorf, MD Associate Neema Navai, MD Assistant Quynh N. Nguyen, MD Assistant Radiation Oncology Victor G. Prieto, MD, PhD Chair, Ad interim & Pathology Administration David C. Rice, MD Thoracic & Cardiovascular Surgery Merrick I. Ross, MD Aysegul A. Sahin, MD Pathology Administration Kathleen M. Schmeler, MD Associate Gynecologic Oncology & Reproductive Medicine Jay B. Shah, MD Assistant Erich M. Sturgis, MD Head & Neck Surgery Stephen G. Swisher, MD Chair & Thoracic & Cardiovascular Surgery Vicente Valero, MD Breast Medical Oncology Jeffrey S. Weinberg, MD Associate Neurosurgery Robert A. Wolff, MD Chair Ad Interim & Investigational Cancer Therapeutics Christopher G. Wood, MD Y. Nancy You, MD Assistant Guest Faculty Robert H. Andtbacka, MD Assistant Division of University of Utah School of Medicine Huntsman Cancer Institute Salt Lake City, Utah Karl Y. Bilimoria, MD Assistant, Surgery Northwestern University Feinberg School of Medicine Chicago, Illinois Steven A. Curley, MD Michael E. DeBakey Department of Surgery Baylor College of Medicine Houston, Texas REGISTRATION INFORMATION On-site registration for the Advances and Controversies, will open at 3:00 pm on Friday, January 16, 2015, and the conference will begin at 5:00 pm on Friday, January 16, 2015, followed by a Welcome Reception. The conference will adjourn at 1:00 pm on Monday, January 19, Advance registration is encouraged as space and materials are limited. Please see registration form for applicable fees. The deadline for advance registration is January 5, There are three ways to register: Mail to CME/Conference Management Unit 1781, The University of Texas MD Anderson Cancer Center, P. O. Box , Houston, TX Fax to Register on-line at We accept the following forms of payment: Check (payable through U.S. banks only) Money order Credit cards (MasterCard, VISA, and American Express) Cash (on-site registration only) When registering on-line a receipt/confirmation letter will automatically be ed to the address you list on the registration form. If you register by fax or mail a receipt/ confirmation letter will be sent to you within ten working days of receipt of your fee. The conference registration fee includes the tuition, final program, continental breakfasts, coffee breaks, and welcome reception. REFUND/CANCELLATION POLICY The registration fee, minus a $50 administrative handling fee, is refundable if a written request is received on or before January 5, No refunds will be granted after that date. The request for a registration refund must include the tax identification number of the company or institution if registration was paid by a company or institution check. For additional information, contact CME/Conference Management at or toll free at The Department of CME/Conference Management reserves the right to cancel activities prior to the scheduled date, if low enrollment or other circumstances make it necessary. Each registrant will be notified by mail, , or the phone or fax numbers given on the registration form. In case of activity cancellation, the liability of the Department of CME/Conference Management is limited to the registration fee. The Department of CME/Conference Management reserves the right to limit the number of participants in a program and is not responsible for any expenses incurred by an individual whose registration is not confirmed and for whom space is not available. For additional information, contact CME/Conference Management at or

6 ACCOMMODATIONS A block of rooms has been reserved for conference attendees at the Sheraton Steamboat Hotel, 2220 Village Inn Court, Steamboat Springs, Colorado. Early hotel reservation is suggested. The hotel phone number is Website: When you make reservations, be sure to mention the MD Anderson 13th Oncology Update: Advances and Controversies Conference to be assured of receiving the special meeting rate of $ Condos and suites are available. Call hotel for rates. Please add 11.65% state and local taxes. Reservations and deposits received after December 18, 2014, will be confirmed if space is available and at currently published hotel guest room rates. Rooms are guaranteed 30 days prior to arrival by taking a full deposit of the entrie stay. Upon the taking of the deposit all reservations are unchangeable. If cancelled the deposit is non-refundable. THIS IS NOT A SELF-MAILER ADDRESS TO: Advances and Controversies Department of CME/Conference Management Unit 1781 The University of Texas MD Anderson Cancer Center PO Box , Houston, TX or fax to Make check or money order payable to: The University of Texas MD Anderson Cancer Center REGISTRATION FEES Advances and Controversies, January 16 19, 2015 Physicians 1 Postmarked before 1/5/15...$ Postmarked after 1/5/15...$ MD Anderson Faculty 1 Postmarked before 1/5/15...$ Postmarked after 1/5/15...$ Fellows, Physician Assistants, Nurses, Social Workers 1 Postmarked before 1/5/15...$ Postmarked after 1/5/15...$ SKI EQUIPMENT RENTAL Ski rentals are available through and enter the group code: SHMD. You will receive a 35% discount when booked in advance and a 30% discount on site. Lift ticket discount is 5%. Coupons will be available at registration. GROUND TRANSPORTATION The Sheraton Steamboat Hotel is 22 miles from the Yampa Valley Regional Airport in Hayden (locator code: HDN) and is served by United, Delta, Northwest, and American Airlines. Transportation from the Yampa Valley Regional Airport is available by GO Alpine Airport Shuttle at $35.20/person one way or $55.00/person round trip. Advance reservations are strongly suggested, since walk-up passengers are boarded on a space available basis only. Reservations can be made on-line up to 48 hours beforehand at or by phone at SPECIAL ASSISTANCE Contact the Department of CME/Conference Management at or if you have any special dietary or ADA accommodation needs. Please let us know what specific topics, issues or questions you wish to see addressed or emphasized in this activity. Fax or CME/Conference Management. All responses will be forwarded to the Program Chairs for consideration. The University of Texas MD Anderson Cancer Center has implemented a process whereby everyone who is in a position to control the content of an educational activity must disclose all relevant financial relationships with any commercial interest that could potentially affect the information presented. MD Anderson also requires that all faculty disclose any unlabeled use or investigational use (not yet approved for any purpose) of pharmaceutical and medical device products. Specific disclosure will be made to the participants prior to the educational activity. Agendas are subject to change because we are always striving to improve the quality of your educational experience. MD Anderson may substitute faculty with comparable expertise on rare occasions necessitated by illness, scheduling conflicts, and so forth. CONFERENCE REGISTRATION / Advances and Controversies January 16 19, 2015 Last Name First MI Highest Degree Department (include box no.) Specialty Institution Physician oyes ono Street City State/Foreign Country/Zip or Mail Code Daytime Phone (with area code) Cell Phone (with area code) Fax (with area code) Address (please print) Emergency Contact Phone (with area code) Charge the following: ovisa omastercard oamerican Express Credit Card Holder Name (First/Last) Credit Card Holder Billing Address & ZIP Code Credit Card Number Expiration Date MD Anderson Interdepartmental Transfer (IDT) No.: *Fund Group 90 will not be accepted Business Unit Department Fund Group* Fund Fund Type Authorized Signature REQUIRED for credit card or IDT MD Anderson Employee ID No. (REQUIRED) IDT Approver Name (First/Last) please print IDT Approver Photographing, audio taping and videotaping are prohibited.

7 Department of CME/Conference Management - Unit 1781 The University of Texas MD Anderson Cancer Center #176700/30/111607/41 PS PO Box Houston, TX Non-Profit Org. U.S. Postage P A I D Houston, TX Permit No. 7052

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