Supporting Information. Synthesis of Zwitterionic Polymer Particles via Combined Distillation
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1 Supporting Information Synthesis of Zwitterionic Polymer Particles via Combined Distillation Precipitation Polymerization and Click Chemistry for Highly Efficient Enrichment of Glycopeptide Jianxi Liu, [a, b] Kaiguang Yang, [a] Wenya Shao, [a] Senwu Li, [a] Qi Wu, [a] Shen Zhang, [a] Yanyan Qu, [a] Lihua Zhang *[a] and Yukui Zhang [a] [a] National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian , China [b] College of Environment Science and Engineering, Fujian Normal University, Fuzhou, Fujian , China These two authors contributed equally *Address: 457 Zhongshan Road, Dalian , China Tel/Fax: S-1
2 Figure S-1. X-ray photoelectron survey spectra of elemental a) carbon, b) nitrogen and c) oxygen from Figure S-2. a) X-ray photoelectron survey spectra of Poly(MBAAm-co-MAA) and XPS of elemental b) sulfur, c) carbon, d) nitrogen and e) oxygen from Poly(MBAAm-co-MAA). S-2
3 Figure S-3. MALDI-TOF spectra of 3.34 pmol human IgG digest after enrichment with and then deglycosylation by PNGase F. S-3
4 Figure S-4. MALDI-TOF spectra of 3.34 pmol human IgG digest after (a) the 1 st cycled enrichment with Poly(MBAAm-co-MAA)@L-Cys, (b) (e) after the 2 nd -5 th cycled enrichment with the materials. S-4
5 Figure S-5. Biological process (a), cellular component (b) and molecular function (c) of glycoproteins identified from human plasma. The results were obtained from GoMiner. S-5
6 Table S-1. Molecular masses and proposed oligosaccharide composition of glycopeptides enriched from IgG digests. N# denotes the N-linked glycosylation site. Number m/z Glycan composite Amino acid sequence Hex3 HexNAc3 Fuc1 EEQFN#STFR Hex4 HexNAc3 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 EEQFN#STYR Hex4 HexNAc4 Fuc1 EEQFN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQFN#STFR Hex3 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQFN#STFR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex5 HexNAc5 EEQYN#STYR Hex5 HexNAc5 Fuc1 EEQFN#STFR Hex5 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fuc1 NeuAc1 EEQFN#STFR S-6
7 Table S-2. Molecular masses and proposed oligosaccharide composition of glycopeptides enriched from the mixture of IgG and BSA digests. N# denotes the N-linked glycosylation site. Number m/z Glycan composite Amino acid sequence Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 EEQFN#STYR Hex4 HexNAc4 Fuc1 EEQFN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQFN#STFR Hex3 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQFN#STFR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex5 HexNAc5 EEQYN#STYR Hex5 HexNAc5 Fuc1 EEQFN#STFR Hex5 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fuc1 NeuAc1 EEQFN#STFR Hex5 HexNAc4 Fuc1 NeuAc1 EEQYN#STYR S-7
8 Table S-3-(a). Molecular masses and proposed oligosaccharide composition of glycopeptides after (a) the 1 st cycled enrichment with Poly(MBAAm-co-MAA)@L-Cys, (b) (c) after the 2 nd -5 th cycled enrichment with the materials. N# denotes the N-linked glycosylation site. m/z Glycan composite Amino acid sequence Hex3 HexNAc3 Fuc1 EEQFN#STFR Hex3 HexNAc3 Fuc1 EEQYN#STYR Hex4 HexNAc3 Fuc1 EEQFN#STYR Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex4 HexNAc4 EEQYN#STYR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQFN#STFR Hex4 HexNAc5 EEQYN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQFN#STFR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex4 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR Hex5 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR S-8
9 Table S-3-(b). m/z Glycan composite Amino acid sequence Hex3 HexNAc3 Fuc1 EEQFN#STFR Hex3 HexNAc3 Fuc1 EEQYN#STYR Hex4 HexNAc3 Fuc1 EEQFN#STFR Hex4 HexNAc3 Fuc1 EEQFN#STYR Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex4 HexNAc4 Fuc1 EEQYN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex5 HexNAc4 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQFN#STFR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex4 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR Hex5 HexNAc5 Fuc1 EEQFN#STFR Hex5 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR S-9
10 Table S-3-(c). m/z Glycan composite Amino acid sequence Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex4 HexNAc4 Fuc1 EEQYN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQFN#STFR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex4 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR Hex5 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR S-10
11 Table S-3-(d). m/z Glycan composite Amino acid sequence Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex4 HexNAc4 Fuc1 EEQYN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQYN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex5 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR S-11
12 Table S-3-(e). Number m/z Glycan composite Amino acid sequence Hex3 HexNAc4 Fuc1 EEQFN#STFR Hex3 HexNAc4 Fuc1 EEQYN#STYR Hex4 HexNAc4 Fuc1 EEQYN#STFR Hex4 HexNAc4 Fuc1 EEQYN#STYR Hex3 HexNAc5 Fuc1 EEQFN#STYR Hex5 HexNAc4 Fun1 EEQFN#STFR Hex5 HexNAc4 Fun1 EEQYN#STYR Hex4 HexNAc5 Fun1 EEQYN#STYR Hex4 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR Hex5 HexNAc4 NeuAc1 Fuc1 EEQYN#STYR S-12
13 Table S-4. List of identified glycoproteins enriched by from the digests of 5 μg human plasma. No. Protein Description/Glycopeptides sequences 1 IPI Isoform 1 of CD109 antigen TQDEILFSN#STR 2 IPI Complement component C6 precursor VLN#FTTK 3 IPI Isoform LAMP-2A of Lysosome-associated membrane glycoprotein 2 VASVININPN#TTHSTGSCR 4 IPI Isoform 1 of Alpha-1-antichymotrypsin LINDYVKN#GTR KLINDYVKN#GTR TLN#QSSDELQLSMGNAMFVK 5 IPI Isoform 2 of Ig mu chain C region GLTFQQN#ASSMCVPDQDTAIR THTN#ISESHPN#ATFSAVGEASICEDDWNSG ER 6 IPI Prostaglandin-H2 D-isomerase WFSAGLASN#SSWLR 7 IPI Intercellular adhesion molecule 1 LNPTVTYGN#DSFSAK 8 IPI Isoform 2 of UDP-GlcNAc:betaGal beta-1,3-n-acetylglucosaminyltransferase 2 LSN#ISHLNYCEPDLR 9 IPI Uncharacterized protein TELFSSSCPGGIMLN#ETGQGYQR 10 IPI Complement factor I LSDLSIN#STECLHVHCR FLNN#GTCTAEGK 11 IPI Apolipoprotein D CIQAN#YSLMENGK ADGTVNQIEGEATPVN#LTEPAKLEVK ADGTVNQIEGEATPVN#LTEPAK 12 IPI FLJ00385 protein (Fragment) TKPREEQFN#STFR EEQFN#STFR 13 IPI Isoform 1 of Peptidase inhibitor 16 SLPNFPN#TSATAN#ATGGR 14 IPI Haptoglobin VVLHPN#YSQVDIGLIK NLFLN#HSEN#ATAK S-13
14 MVSHHN#LTTGATLINEQWLLTTAK 15 IPI Heparin cofactor 2 GGETAQSADPQWEQLNNKN#LSMPLLPADF HK 16 IPI Lumican LHINHNN#LTESVGPLPK AFEN#VTDLQWLILDHNLLENSK KLHINHNN#LTESVGPLPK 17 IPI Insulin-like growth factor-binding protein 3 GLCVN#ASAVSR YKVDYESQSTDTQN#FSSESKR AYLLPAPPAPGN#ASESEEDR 18 IPI Isoform 1 of Multimerin-1 VN#ESVVSIAAQQK TQAALSN#LTCCIDR HPFTGDN#CTIK 19 IPI Pigment epithelium-derived factor VTQN#LTLIEESLTSEFIHDIDRELK VTQN#LTLIEESLTSEFIHDIDR 20 IPI Antithrombin-III LGACN#DTLQQLMEVFK SLTFN#ETYQDISELVYGAK 21 IPI Thrombospondin-1 KVSCPIMPCSN#ATVPDGECCPR VSCPIMPCSN#ATVPDGECCPR VVN#STTGPGEHLR 22 IPI kda protein VVLHPN#YSQVDIGLIK NLFLN#HSEN#ATAK MVSHHN#LTTGATLINEQWLLTTAK 23 IPI Receptor-type tyrosine-protein phosphatase eta precursor IHVAGETDSSNLN#VSEPR 24 IPI Vitronectin NN#ATVHEQVGGPSLTSDLQAQSK 25 IPI Putative uncharacterized protein DKFZp686N02209 TKPREEQYN#STYR 26 IPI Cartilage oligomeric matrix protein CN#DTIPEDYETHQLR 27 IPI Coagulation factor XIII B chain HGVIISSTVDTYEN#GSSVEYR EHETCLAPELYNGN#YSTTQK KEHETCLAPELYNGN#YSTTQK 28 IPI Serotransferrin QQQHLFGSN#VTDCSGNFCLFR S-14
15 29 IPI Putative uncharacterized protein DKFZp686M24218 TKPREEQFN#STYR EEQFN#STYR 30 IPI Complement component C9 AVN#ITSENLIDDVVSLIR 31 IPI Biotinidase DVQIIVFPEDGIHGFN#FTR FN#DTEVLQR NPVGLIGAEN#ATGETDPSHSK 32 IPI Butyrylcholinesterase, isoform CRA_b DN#YTKAEEILSR WSDIWN#ATK 33 IPI Lymphatic vessel endothelial hyaluronic acid receptor 1 KANQQLN#FTEAK ANQQLN#FTEAK 34 IPI Thyroxine-binding globulin TLYETEVFSTDFSN#ISAAK VTACHSSQPN#ATLYK 35 IPI Complement C4-A GLN#VTLSSTGRNGFK FSDGLESN#SSTQFEVK N#TTCQDLQIEVTVK FSDGLESN#SSTQFEVKK GLN#VTLSSTGR 36 IPI Isoform 1 of Clusterin MLN#TSSLLEQLNEQFNWVSR LAN#LTQGEDQYYLR LKELPGVCN#ETMMALWEECKPCLK ELPGVCN#ETMMALWEECKPCLK 37 IPI Angiopoietin-related protein 6 ATPEAAN#ASELAALR 38 IPI Apolipoprotein M TELFSSSCPGGIMLN#ETGQGYQR 39 IPI Uncharacterized protein IGYSNN#GSDWK 40 IPI Isoform 1 of Mitogen-activated protein kinase kinase kinase 8 HLN#VSDVIDIMENLYASEEPAVYEPSLMTM CQDSNQNDER 41 IPI Ceruloplasmin ELHHLQEQN#VSNAFLDKGEFYIGSK EHEGAIYPDN#TTDFQR ELHHLQEQN#VSNAFLDK EN#LTAPGSDSAVFFEQGTTR 42 IPI Isoform B of Fibulin-1 S-15
16 CATPHGDN#ASLEATFVK 43 IPI Isoform 2 of Carboxypeptidase B2 QVHFFVN#ASDVDNVK KQVHFFVN#ASDVDNVK 44 IPI Complement C1r subcomponent EHEAQSN#ASLDVFLGHTNVEELMK 45 IPI Complement C3 (Fragment) TVLTPATNHMGN#VTFTIPANR 46 IPI C4b-binding protein alpha chain FSLLGHASISCTVEN#ETIGVWRPSPPTCEK LSVDKDQYVEPEN#VTIQCDSGYGVVGPQSI TCSGNR 47 IPI cdna FLJ55673, highly similar to Complement factor B LTDTICGVGN#MSAN#ASDQER QSVPAHFVALN#GSK TMFPN#LTDVR 48 IPI Complement C2 (Fragment) LTDTICGVGN#MSAN#ASDQER QSVPAHFVALN#GSK TMFPN#LTDVR 49 IPI Isoform 1 of Tudor domain-containing protein 10 LFVN#TSK 50 IPI Cadherin-5 ELDREVYPWYN#LTVEAK 51 IPI Complement component C8 beta chain EYESYSDFERN#VTEK 52 IPI cdna FLJ55606, highly similar to Alpha-2-HS-glycoprotein AALAAFNAQNN#GSNFQLEEISR KVCQDCPLLAPLN#DTR VCQDCPLLAPLN#DTR 53 IPI Apolipoprotein B-100 VNQNLVYESGSLN#FSK FN#SSYLQGTNQITGR FVEGSHN#STVSLTTK FEVDSPVYN#ATWSASLK 54 IPI Isoform 1 of N-acetylmuramoyl-L-alanine amidase GFGVAIVGN#YTAALPTEAALR LEPVHLQLQCMSQEQLAQVAAN#ATK 55 IPI Hemopexin ALPQPQN#VTSLLGCTH GHGHRN#GTGHGN#STHHGPEYMR ERSWPAVGN#CSSALR SWPAVGN#CSSALR S-16
17 56 IPI Vitamin K-dependent protein C EVFVHPN#YSK 57 IPI Putative uncharacterized protein DKFZp686I04196 (Fragment) TKPREEQFN#STFR EEQFN#STFR 58 IPI IgGFc-binding protein YLPVN#SSLLTSDCSER 59 IPI Isoform 1 of Cell adhesion molecule 1 VSLTN#VSISDEGR 60 IPI Corticosteroid-binding globulin AQLLQGLGFN#LTER 61 IPI Isoform 1 of Cholesteryl ester transfer protein GVVVN#SSVMVK 62 IPI Isoform 1 of Extracellular matrix protein 1 HIPGLIHN#MTAR 63 IPI Beta-Ala-His dipeptidase LVPHMN#VSAVEK 64 IPI Isoform 1 of Complement factor H SPDVIN#GSPISQK MDGASN#VTCINSR WDPEVN#CSMAQIQLCPPPPQIPNSHN#MTT TLNYR IPCSQPPQIEHGTIN#SSR SPYEMFGDEEVMCLNGN#WTEPPQCK 65 IPI Putative uncharacterized protein DKFZp686C02218 (Fragment) LSLHRPALEDLLLGSEAN#LTCTLTGLR TPLTAN#ITK LAGKPTHVN#VSVVMAEVDGTCY 66 IPI Carboxypeptidase N subunit 2 LYLGSNN#LTALHPALFQN#LSK AFGSNPN#LTK 67 IPI Isoform 1 of Mast/stem cell growth factor receptor SLYGKEDN#DTLVR 68 IPI Isoform 1 of Phosphatidylinositol-glycan-specific phospholipase D LGTSLSSGHVLMN#GTLK 69 IPI Immunoglobulin J chain IIVPLNNREN#ISDPTSPLR EN#ISDPTSPLR 70 IPI Putative uncharacterized protein DKFZp686C02220 (Fragment) LSLHRPALEDLLLGSEAN#LTCTLTGLR HYTN#SSQDVTVPCR HYTN#SSQDVTVPCRVPPPPPCCHPR TPLTAN#ITK MAGKPTHIN#VSVVMAEADGTCY S-17
18 71 IPI kda protein NSVLN#SSTAEHSSPYSEDPIEDPLQPDVTGI R 72 IPI Putative apolipoprotein(a)-like protein 2 WEYCN#LTR 73 IPI Polymeric immunoglobulin receptor VPGN#VTAVLGETLK LSLLEEPGN#GTFTVILNQLTSR WN#NTGCQALPSQDEGPSK 74 IPI Full-length cdna clone CS0DD006YL02 of Neuroblastoma of Homo sapiens STGKPTLYN#VSLVMSDTAGTCY THTN#ISESHPN#ATFSAVGEASICEDDWNSG ER 75 IPI Isoform 1 of Attractin IDSTGN#VTNELR MPSQAPTGNFYPQPLLN#SSMCLEDSR AATCINPLN#GSVCERPAN#HSAK N#HSCSEGQISIFR DLDMFIN#ASK 76 IPI Isoform 2 of Ig delta chain C region TLLN#ASR 77 IPI Prothrombin (Fragment) YPHKPEIN#STTHPGADLQENFCR SRYPHKPEIN#STTHPGADLQENFCR 78 IPI Zinc-alpha-2-glycoprotein DIVEYYN#DSN#GSHVLQGR 79 IPI haptoglobin isoform 2 preproprotein VVLHPN#YSQVDIGLIK NLFLN#HSEN#ATAK MVSHHN#LTTGATLINEQWLLTTAK 80 IPI Isoform 2 of Phospholipid transfer protein EGHFYYN#ISEVK 81 IPI Isoform 2 of Inter-alpha-trypsin inhibitor heavy chain H4 LPTQN#ITFQTESSVAEQEAEFQSPK 82 IPI Protein XESMLN#ATTRRMLSHSSGAVR 83 IPI Arachidonate 5-lipoxygenase EQLICECGLFDKAN#ATGGGGHVQMVQR 84 IPI Alpha-1-acid glycoprotein 1 QDQCIYN#TTYLNVQR 85 IPI Isoform 1 of ADAMTS-like protein 4 LVSGN#LTDR 86 IPI Pantetheinase S-18
19 LTGVAGN#YTVCQK 87 IPI Isoform 1 of Alpha-1-antitrypsin YLGN#ATAIFFLPDEGK YLGN#ATAIFFLPDEGKLQHLENELTHDIIT K ADTHDEILEGLNFN#LTEIPEAQIHEGFQEL LR 88 IPI Alpha-1-acid glycoprotein 2 QNQCFYN#SSYLNVQR 89 IPI Vasorin LHEITN#ETFR 90 IPI L-selectin precursor DN#YTDLVAIQNK FCRDN#YTDLVAIQNK 91 IPI Complement C1q subcomponent subunit A RNPPMGGNVVIFDTVITNQEEPYQN#HSGR NPPMGGNVVIFDTVITNQEEPYQN#HSGR 92 IPI Galectin-3-binding protein ALGFEN#ATQALGR AAIPSALDTN#SSK 93 IPI Selenoprotein P CGN#CSLTTLKDEDFCKR KCGN#CSLTTLKDEDFCK 94 IPI Isoform HMW of Kininogen-1 ITYSIVQTN#CSK 95 IPI Putative uncharacterized protein DKFZp686I15212 TKPREEQYN#STFR EEQYN#STFR 96 IPI Inter-alpha (Globulin) inhibitor H2, isoform CRA_a GAFISN#FSMTVDGK 97 IPI Complement factor H-related protein 1 LQNNENN#ISCVER SPYEMFGDEEVMCLNGN#WTEPPQCK 98 IPI Alpha-2-macroglobulin GCVLLSYLN#ETVTVSASLESVR SLGNVN#FTVSAEALESQELCGTEVPSVPEH GR SLGNVN#FTVSAEALESQELCGTEVPSVPEH GRK 99 IPI kda protein MLQITN#ASLGLR 100 IPI Complement C1s subcomponent NCGVN#CSGDVFTALIGEIASPNYPKPYPEN SR S-19
20 101 IPI Isoform 1 of Fibronectin DQCIVDDITYNVN#DTFHK LDAPTNLQFVN#ETDSTVLVR 102 IPI Afamin ICAMEGLPQKHN#FSHCCSK 103 IPI Coagulation factor XII RN#HSCEPCQTLAVR 104 IPI Serum paraoxonase/arylesterase 1 VTQVYAEN#GTVLQGSTVASVYK HAN#WTLTPLK 105 IPI Isoform 1 of Coagulation factor XI LETTVN#YTDSQRPICLPSK LETTVN#YTDSQRPICLPSKGDR VYSGILN#QSEIK 106 IPI CDNA FLJ25298 fis, clone STM07683, highly similar to Protein Tro alpha1 H,myeloma LSLHRPALEDLLLGSEAN#LTCTLTGLR LAGKPTHVN#VSVVMAEVDGTCY 107 IPI Complement C1r subcomponent-like protein QNESHN#FSGDIALLELQHSIPLGPNVLPVC LPDN#ETLYR KN#QSVNVFLGHTAIDEMLK DRQDGEEVLQCMPVCGRPVTPIAQN#QTTL GSSR 108 IPI Isoform 1 of Neutrophil gelatinase-associated lipocalin SYN#VTSVLFR 109 IPI Histidine-rich glycoprotein VIDFN#CTTSSVSSALANTK 110 IPI Isoform 1 of Scavenger receptor cysteine-rich type 1 protein M130 HSN#CTHQQDAGVTCSDGSNLEMR 111 IPI Ig mu heavy chain disease protein STGKPTLYN#VSLVMSDTAGTCY THTN#ISESHPN#ATFSAVGEASICEDDWDSG ER 112 IPI Beta-2-glycopr otein 1 DTAVFECLPQHAMFGN#DTITCTTHGN#WT KLPECR VYKPSAGN#NSLYR LGN#WSAMPSCK DTAVFECLPQHAMFGN#DTITCTTHGN#WT K 113 IPI Angiotensinog en S-20
21 LQAILGVPWKDKN#CTSR 114 IPI Plasma kallikrein IYSGILN#LSDITK LQAPLN#YTEFQKPICLPSK IYPGVDFGGEELN#VTFVK GVNFN#VSK IVGGTN#SSWGEWPWQVSLQVK 115 IPI Isoform 1 of Uncharacterized protein C2orf67 NILYN#GSNIQLSK 116 IPI Isoform 1 of Tandem C2 domains nuclear protein ATEFIKSCCGGCFYGETEKHN#FSVER 117 IPI Serum amyloid A-4 protein VYLQGLIDCYLFGN#SSTVLEDSK 118 IPI Isoform 12 of CD44 antigen AFN#STLPTMAQMEK 119 IPI Kallistatin SQILEGLGFN#LTELSESDVHR DFYVDEN#TTVR FLN#DTMAVYEAK 120 IPI Dopamine beta-hydroxylase SLEAIN#GSGLQMGLQR 121 IPI Isoform 1 of C4b-binding protein beta chain KTLFCNASKEWDN#TTTECR LGHCPDPVLVNGEFSSSGPVN#VSDK TLFCN#ASKEWDN#TTTECR S-21
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