DEVELOPMENTAL ANATOMY OF THE FACE, JAW AND NECK. O.M. Oluwatosin Department of Surgery

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1 DEVELOPMENTAL ANATOMY OF THE FACE, JAW AND NECK O.M. Oluwatosin Department of Surgery 1

2 2 By the end of this lecture, you should be able to: Discuss the embryology of the face Relate congenital anomalies of the face to aberrations of development Describe the surgical anatomy of facial structures

3 3 Six mm embryo

4 Eyes Optic vesicles grow out as diverticula from forebrain Connect with lens pit and lens vesicle from ectoderm Optic cup develops into retina Ectoderm: Lacrimal gland develops from ectoderm Also epithelium of corneo-conjuctivae Naso-lacrimal duct thickening of ectoderm in nasomaxillary groove. Eyelids small fold of skin. Fuse at 3rd month until 6th 4

5 5 External ears External meatus derived from dorsal end of first bronchial groove Auricle develops 6 hillocks around margins of first branchial groove at (4mm embryo) mesenchyme of second branchial arch

6 6 Lateral derivatives of pharyngeal pouches Pharyngeal grooves and pouches (opening into pharynx) separate the pharyngeal arches Pouch Dorsal diverticulum Ventral diverticulum 1st Eustachian tube, middle ear Mastoid, antrum 2nd Middle ear. Tonsillar crypts, Supratonsilar fossa 3rd Inferior parathyroid Superior parathyroid Thymus 4th 5th Ultimobranchial body

7 7 Ventral derivatives of pharyngeal pouches Development of the Tongue Tongue tuberculum impar, lateral rudiments. Foramen caecum. Copula of His. Last 3-4 occipital myotomes. Thyroid gland thyroglossal duct. Larynx, tracheal airway

8 8 20 mm embryo

9 9 Thyroglossal cyst

10 10

11 Arch Skeleton 1st Maxilla, palate Mandible (Meckel s cartilage disappears) Incus, Maleus Mandibular 2nd Hyoid 3rd Thyro-hoid 4th 5th 11 Derivatives of the arches Muscle (mesoderm) Muscles of mastication (masseter, temporalis, pterygoids), mylohoid, tensor palati tympani, digastric (anterior belly) Stapes, stytoid Stapedius, stylohyoid, process, digastric (posterior Lesser cornu, upper belly). Muscles of part of hyoid body facial expression, (Reichert s buccinator, platysma Cartilage) Greater cornu lower Stylopharyngeus part of hyoid body Thyroid cartilage, arytenoid, corniculate and cuneiform cartilages?cricoid (may be a modified tracheal ring). Cricothyroid Remaining laryngeal muscles Artery Nerve Internal (Mandibular st Maxillary (1 branch of aortic arch) Trigeninal) 2nd aortic arch (mainly rudimentary as stapedial art.?facial artery Part of internal carotid Endoderm Mucosa of anterior of tongue Facial nerve Glossopharyn Mucosa geal of posterior 1/3 of tongue, anterior surface of epiglotis, valleculae Superior laryngeal Recurrent Laryngeal

12 12 Cystic hygroma

13 13 Classification of craniofacial anomalies Clefts Synostosis Hypoplasias Head and neck surgery; Plastic Surgery, University of Ibadan

14 Clefts Failure of mesodermal merging. Failure of fusion of facial processes Incidence: 1: : (Nigeria) Head and neck surgery; Plastic Surgery, University of Ibadan 14

15 Theories in the formation of clefts Classical theory (Dursy, His) Once epithelial contact is established, mesodermal penetration completes the fusion process Mesodermal penetration theory (Pohlmann, Veau) No free ends of facial process, there is bilaminar membrane with seams demarcating the major processes, mesoderm penetrates and smoothes out the seams, 15

16 Etiological factors 16 Radiation: microcephaly Infection: toxoplasmosis, rubella, CMV Maternal idiosyncracies phenylketonuria disorder, diabetes (oculoauriculovertebral OAV spectrum) Chemicals: vitamin deficiency states, excess Vit A, isotretinoin (clefts, microsomia), thalidomide, diazepam (cleft palate), phenytoin

17 17 CLASSIFICATION OF CLEFTS American cleft palate association Tessier

18 Clefts: 18 types and nomenclature Complete unilateral cleft of primary palate: nose,lip, gingiva, premaxilla Point of division: Foramen incissura Cleft of secondary palate: hard and soft palate,uvula

19 19

20 20 Unoperated cleft lip

21 21 Tessier s classification of clefts Head and neck surgery; Plastic Surgery, University of Ibadan

22 Clefts: treatment Type of cleft Timing 22 Method Cleft of primary palate Rule of 10s: Age=10 weeks Wt =10 Ib, Hb =10 G/dl Rotation advancement flap repair (Millard) Cleft of secondary palate Age=6 months Langenbeck s Head and neck surgery; Plastic Surgery, University of Ibadan Advancement Furlow flap

23 23 Hypoplasia Van der Muelen classification

24 24 Head and neck surgery; Plastic Surgery, University of Ibadan

25 25 Frontosphenoidal dysplasia

26 Frontal dysplasia 26

27 27 Craniosynostosis: pathogenesis Abnormal tensile forces transmitted to the dura from an anomalous cranial base through key ligamentous attachments Fetal head constraints Sutural abnormality Shunt decompression of hydrocephalus

28 28

29 29 Craniosynostoses Skull shape Trigonocephaly Triangular Abnormally closed suture Metopic Scaphocephaly Boat shaped Sagittal Turricephaly Skull height Basal Oxycephaly Pointed head Coronal

30 30 Scaphocephaly Turricephaly

31 31

32 32

33 33 Metopic synostosis

34 34 Craniosynostosis: functional problems Intracranial hypertension Visual impairment Neuropsychiatric disorders Head and neck surgery; Plastic Surgery, University of Ibadan

35 Medialization of the two orbits using original Tessier procedure 35

36 36 Head and neck surgery; Plastic Surgery, University of Ibadan

37 The face: sensory nerve supply Remember!! Trigeminal nerve also supplies the muscles of mastication

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