BROCHURE w w w. v i r o l o g y e d u c a t i o n. c o m

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1 BROCHURE w w w. v i r o l o g y e d u c a t i o n. c o m Jointly sponsored by UC San Diego School of Medicine

MD, PhD (chair 2012) Stellenbosch University, S. Africa Edmund Capparelli, PharmD (Primary Course Director) University of California San Diego, USA Patricia Flynn, MD St.

2 w w w.v i r o l o g y e d u c a t i o n. c o m Dear colleague, Organizing Committee Jintanat Ananworanich, MD, PhD The Thai Red Cross, AIDS Research Center, Thailand Charles Boucher, MD, PhD Erasmus University, the Netherlands Mark Cotton, MD, PhD (chair 2012) Stellenbosch University, S. Africa Edmund Capparelli, PharmD (Primary Course Director) University of California San Diego, USA Patricia Flynn, MD St. Jude Children's Research Hospital, USA Carlo Giaquinto, MD University of Padova, Italy Dorothy Mbori-Ngacha, MBChB MMed, MPH United Nation Children s Fund, SA It is our great pleasure to announce the 4 th International workshop on HIV Pediatrics, which will be held in Washington DC, USA on 20 & 21 July 2012, preceding the AIDS 2012 Conference. HIV treatment in infants and children differs from HIV treatment in adults, and caregivers face numerous problems when treating these patients, particularly in developing countries. These difficulties include the need for early infant diagnosis to allow early initiation of treatment, lack of data on safety and drug dosing for children using newer drugs, continued problems with availability of pediatric drug formulations, special adherence issues for children, etc. Additionally, prevention of mother to child HIV transmission remains problematic in developing countries, both in terms of implementation of known effective interventions as well as transmission through breastfeeding. These areas of research need more attention, and therefore we have set up a highly focused international workshop on HIV Pediatrics together with a group of experts in this field. The 4 th International Workshop on HIV Pediatrics will continue to present a unique and much needed platform for international interchange on this important topic. The workshop will be abstractdriven and, by bringing together experts from different disciplines who are involved in daily clinical care for infants and children, this meeting will offer an interactive setting where the latest developments in the field can be presented and, more importantly, discussed, reviewed and evaluated. The ultimate goal of this interchange is to cultivate better treatment methods and strategies for infants and children in developed and developing countries. This international workshop aims to bring together virologists, pharmacologists, pediatricians, obstetricians/gynecologists and other interested researchers to present and discuss the latest developments in the field of HIV Pediatrics, Drug Development, and Prevention of Mother to Child Transmission. Lynne Mofenson, MD (chair 2012) National Institutes of Health, USA We would like to encourage you to attend the 4 th International Workshop on HIV Pediatrics and welcome the submission of abstracts on your research and clinical cases in this field. Kind regards, Gareth Tudor-Williams, MD Imperial College, United Kingdom The Organizing Committee

3 Scientific Committee Elaine Abrams, MD Harlem Hospital, Columbia University, USA Ruth Bland, BSc, MBChB, DCH, MRPCH, MD University of KwaZulu-Natal, South Africa David Burger, PharmD, PhD University of Nijmegen, The Netherlands Ellen Chadwick, MD Childrens Memorial Hospital, USA Tsungai Chipato, MBChB Univ. of Zimbabwe Coll. of Health Sciences, Zimbabwe Kulkanya Chokephaibulkit, MD Siriraj hospital/mahidol University, Bangkok Ashraf Hassen Coovadia, MBChB Coronation Women and Children Hospital, South Africa Anita De Ross,i PhD AIDS Reference Center, Italy Marinella Della Negra, MD Hopital Emilio Ribas, Brazil Brian Eley, MD Red Cross Children's Hospital, South Africa Susan Fiscus, PhD University of North Carolina School of Medicine, USA Mary Fowler, MD Makerere University, Uganda Diana Gibb, MD, MRCP, MSc Medical Research Council, UK Tessa Goetghebuer, MD Hôpital St Pierre, Belgium Laura Guay, MD Elizabeth Glaser Pediatric AIDS Foundation, USA Edward Handelsman, MD Division of AIDS, NIAID/NIH, USA Shirin Heidari, PhD International AIDS Society, Switzerland Nick Hellmann, MD Elizabeth Glaser Pediatric AIDS Foundation, USA Chewe Luo, MD, PhD UNICEF, USA Maria Mellado, MD, PhD Hospital Carlos III, Spain Dhayendre Moodley, MSc, PhD Nelson R Mandela School of Medicine, Durban Philippa, Musoke MD Makerere University, Uganda Sharon Nachman, MD SUNY Health Science Center Stony Brook, USA Michal Odermarsky, MD, PhD European Aids Treatment Group, Belgium Paul Palumbo, MD Dartmouth-Hitchcock Medical Center, USA Jorge Pinto, MD, DSc School of Medicine, Federal Univ. of Minas Gerais, Brasil Thanyawee Puthanakit, MD Chulalongkorn University, Bangkok, Thailand Jose Tomas Ramos Amador, MD Hospital Carlos III, Spain Gabriella Scarlatti, MD, PhD Ospedale San Raffaele, Italy Annette Sohn, MD TREAT Asia/amfAR, Bangkok, Thailand Lynda Stranix-Chibanda, MBChB, MMED University of Zimbabwe, Zimbabwe Graham Taylor, MD Imperial College, UK Claire Thorne, BA, MSc, PhD University College London, UK Ung Vibol, MD National Pediatric Hospital, Phnom Penh, Cambodia Evgeny Voronin, MD, PhD Russian Clinical Aids Center, Russia Andrew Wiznia, MD Jacobi Medical Center/Family Based Services, USA

Disclosure statement It is the policy of the University of California, San Diego School of Medicine to ensure balance, independence, objectivity and scientific rigor.

4 Disclosure statement It is the policy of the University of California, San Diego School of Medicine to ensure balance, independence, objectivity and scientific rigor. All persons involved in the selection, development and presentation of content are required to disclose any real or apparent conflicts of interest. All conflicts of interest will be resolved prior to an educational activity being delivered to learners through one of the following mechanisms 1) altering the financial relationship with the commercial interest, 2) altering the individual s control over CME content about the products or services of the commercial interest, and/or 3) validating the activity content through independent peer review. All persons are also required to disclose any discussions of off label/unapproved uses of drugs or devices. Persons who refuse or fail to disclose will be disqualified from participating in the CME activity. Commercial support Principal Supporter:

5 Program Friday 20 July :00h Opening of the Workshop Workshop Chairs Adolescents & HIV 08:15h Overview: Treatment as prevention Myron Cohen, MD, University of North Carolina, USA 08:45h HIV prevention in adolescents in high resource countries Caroline Foster, MBBS, MRCPCH, Imperial College, UK HIV prevention in adolescents in low resource countries Glenda Gray, MD, Perinatal HIV Research Unit, South Africa 09:45h Abstract presentations 10:15h Coffee break 10:45h Abstract presentations 11:45h Lunch incl. Young & early career investigators network lunch with faculty/scientific committee 13:00h Poster viewing session 1 Pediatric Treatment and Cure 14:00h Debate pro and con: Treatment interruption in children can be used as an alternative to continuous therapy Pro: Con: 14:45h Roundtable discussion: Cure of pediatric HIV infection Virology / reservoirs: Immunology: Karina Butler, MB, BCh, FRCPI, Our Lady's Children's Hospital, Ireland Grace John-Stewart, MD, PhD, University of Washington, USA Deborah Persaud, MD, Johns Hopkins Univ. School of Medicine, USA Brigitte Autran, MD, PhD, INSERM U543, France Discussants: Katherine Luzuriaga, MD, University of Massachusetts, USA Paolo Rossi, PD, PhD, Children's Hospital Bambino Gesù, Italy 15:45h Coffee break 16:15h Abstract Presentations 19:00h Dinner

6 Program Saturday 21 July :00h Young investigator poster awards, late breakers Emerging issues in PMTCT 08:45h Roundtable discussion: Elimination of perinatal HIV transmission Speaker: Discussants: James McIntyre, MBChB, FRCOG, Anova Health Institute, S. Africa Benjamin Chi, MD, Centre for Infectious Disease Research, Zambia James Kiarie, MBBCh, MMed, University of Nairobi, Kenya Praphan Phanupak, MD, PhD, The Thai Red Cross AIDS Research Centre, Thailand 09:45h Acute HIV infection in pregnancy/breastfeeding Dhayendre Moodley MSc, PhD, Nelson Mandela School of Medicine, South Africa 10:15h Abstract presentations 10:45h Coffee break 11:15h Abstract presentations 12:00h Lunch 12:45H Poster viewing session 1 Comorbidities / coinfections 13:30h Case presentations Long-term complications of ART: Hepatitis coinfection: Grace Aldrovandi MD, Children's Hospital Los Angeles, USA Etienne Nel MD, Stellenbosch University, South Africa 14:30h Malignancies in pediatrics HIV infection Elena Chiappini MD, PhD, University of Florence, Italy 15:00h Abstract Presentations 15:30h Coffee break 16:00h Debate pro and con: INH preventive therapy should be provided to all HIV-infected children in TB endemic settings Pro: Con: Mark Cotton MD, PhD, Stellenbosch University, South Africa Charles Mitchell MD, MS, University of Miami School of Medicine, USA 16:45h Abstract Presentations 17:15h Closing

Accreditation The 4th International Workshop on HIV Pediatrics has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical

The University of California, San Diego School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

7 Accreditation The 4th International Workshop on HIV Pediatrics has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the University of California, San Diego School of Medicine and Virology Education. The University of California, San Diego School of Medicine is accredited by the ACCME to provide continuing medical education for physicians. The University of California, San Diego School of Medicine designates this live activity for a maximum of 12 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity. Cultural and linguistic competency statement This activity is in compliance with California Assembly Bill 1195 which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. Cultural competency is defined as a set of integrated attitudes, knowledge, and skills that enables health care professionals or organizations to care effectively for patients from diverse cultures, groups, and communities. Linguistic competency is defined as the ability of a physician or surgeon to provide patients who do not speak English or who have limited ability to speak English, direct communication in the patient s primary language. Cultural and linguistic competency was incorporated into the planning of this activity. Additional resources on cultural and linguistic competency and information about AB1195 can be found on the UCSD CME website at

Meeting objectives To gather experts involved HIV Pediatrics in an interactive workshop setting To provide a platform for presentation and discussion of the latest developments in the field.

Hotel L Enfant Plaza. This hotel is located nearby the National Mall, the Smithsonian Museums and other monuments. Address: 480 L'Enfant Plaza, SW, Washington, D.C. 20024 Who should attend?

8 Meeting objectives To gather experts involved HIV Pediatrics in an interactive workshop setting To provide a platform for presentation and discussion of the latest developments in the field. To map all current studies and results To translate new data to treatment guidelines To educate clinicians on how to best implement current and new drugs Meeting venue The meeting will be held at Hotel L Enfant Plaza. This hotel is located nearby the National Mall, the Smithsonian Museums and other monuments. Address: 480 L'Enfant Plaza, SW, Washington, D.C Who should attend? The target audience of the 4 th International Workshop on HIV Pediatrics consists of virologists, pharmacologists, pediatricians, obstetricians, gynaecologists and PhD students active in the field of HIV Pediatrics. Co-submission of abstracts The workshop has been accepted as an Affiliated Independent Event to: AIDS 2012 XIX International AIDS Conference Co-submission of abstracts to both the AIDS 2012 and this workshop is possible.

Abstract submission w w w. v i r o l o g y e d u c a t i o n. c o m We invite you to submit abstracts for a poster or oral presentation.

Accepted abstracts will be published in the journal Reviews in Antiviral Therapy & Infectious Diseases.

young investigators The conference organizers are committed to stimulate active participation of young investigators at the International Workshop on HIV Pediatrics.

9 Abstract submission w w w. v i r o l o g y e d u c a t i o n. c o m We invite you to submit abstracts for a poster or oral presentation. Please visit the Virology Education website for abstract topics and instructions: Accepted abstracts will be published in the journal Reviews in Antiviral Therapy & Infectious Diseases. Deadlines abstract submission: Regular: 20 April 2012 Late-breaker: 18 May 2012 Co-submission of abstracts to both this workshop and the XIX International AIDS Conference is possible Incentive for young investigators The conference organizers are committed to stimulate active participation of young investigators at the International Workshop on HIV Pediatrics. It is therefore that we offer a FREE registration to all young investigators with an accepted abstract. We would like to encourage young investigators to submit an abstract and present their research data at the workshop. Registration We would like to encourage you to register for this important event. Please visit our website to register online. By registering early you will be able to benefit from lower registration fees. Registration deadlines: Early registration: 1 April 2012 Regular registration: 1 June 2012 Late registration: 8 July 2012 Important contacts The Virology Education team of highly skilled and dedicated professionals is always at your service! Fraukje (Kia) Heida, Event Manager, is responsible for the logistical organization of the meeting. fraukje.heida@vironet.com Tel.: Virology Education Biltstraat BJ Utrecht The Netherlands P: +31 (0) F: +31 (0) E: info@virology-education.com Wilco Keulen, Senior scientist, is responsible for the scientific program. wilco.keulen@vironet.com Tel.: Alice Posthumus - Plantinga, Managing Director, is responsible for industry support. alice.posthumus-plantinga@vironet.com Tel.:

MEETING PROSPECTUS. HIV CLINICAL FORUM INTEGRASE INHIBITORS DURBAN, SOUTH AFRICA 16 July 2016

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