Emerging Opportunities Enhancing Awareness of Clinical Trials

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1 You Are Invited to Attend the Inaugural CME/CNE Accredited Scientific Conference! Emerging Opportunities Enhancing Awareness of Clinical Trials *This includes the Ted and Marty Couch Auditorium, and the Atrium. Saturday October 7, :00 am 3:00 pm Moffitt Cancer Center Stabile Research Building (SRB)* USF Magnolia Drive, Tampa, FL 33612

2 Emerging Opportunities Enhancing Awareness of Clinical Trials Information about the 2017 Breast Immune-Oncology Conference Under the direction of Program Chair, Brian Czerniecki, MD, PhD, and in partnership with Moffitt Cancer Center, The Florida Society of Clinical Oncology (FLASCO), and the accreditor, Rush University Medical Center of Chicago, the 2017 Breast Immune-Oncology Conference will be a first in class scientific event dedicated to the advancement of immune-oncology in breast cancer. The goal of this conference is to examine the role of the immune system in breast cancer, along with the rationale for immunotherapy as a treatment for breast cancer, results from ongoing clinical trials of immunotherapies in breast cancer and learn of current opportunities for trials actively accruing in breast immune-oncology. Attendees will learn about the appropriate clinical trials of immunotherapies for patients with breast cancer, as well as gain insights into the use of standard therapies such as chemotherapy and radiation and how these modalities impact both favorably and unfavorably on the tumor immune response.

3 Educational Objectives After completing this activity, participants should be able to: å review fundamentals of immunology to develop a baseline of scientific understanding that can be applied to clinical translation ç Describe cancer immunotherapy principles in the context of current therapy decisions for the treatment of breast cancer é Discuss promising immunotherapy approaches for breast cancer, including vaccines and the role of checkpoint blockade è Determine how knowledge of response criteria and biomarkers in other tumor types may be used or applied to provide insight in assessing response to immunotherapy ê summarize data from recent and ongoing clinical trials of vaccines and immunotherapies as well as combination therapies currently being studied in breast cancer Target Audience This activity is designed to meet the educational needs of healthcare professionals involved in the treatment of patients with breast cancer. Providers This activity is co-provided by Moffitt Cancer Center, the Florida Society of Clinical Oncology (FLASCO), Rush University, PleXus Communications, and Pennies in Action. Accreditation Information Rush University Medical Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Rush University Medical Center designates this Live Activity for a maximum of two (2) AMA PRA Category 1 Credits. Physicians should claim only credit commensurate with the extent of their participation in the activity. Rush University is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center s Commission on Accreditation. Rush University designates this live activity for two (2) Continuing Education credits. Registration Fee Advance On-site Physicians $ $ Fellows $ $ Nurses, NP, PAs, Pharm, Other $ $ Industry $ $ Accommodations A room block for conference attendees has been set up at the Tampa Marriott Waterside Hotel & Marina. The reduced rate for Friday, October 6 and Saturday, October 7 is $239/night. To make your reservations, go to or call Reservations Toll-Free: Reservations must be made on or before September 6, 2017 to ensure discounted group rate. A free shuttle service will be provided between the Marriott and the Moffitt Cancer Center for all conference particpants.

4 Agenda 8:00 am 10:00 am Session I: Impact of Immune Response on Breast Cancer ß Principles of Breast Tumor Immunology (Jose Conejo-Garcia/Co-chair) ß how understanding the Breast Immune Response will lead to Improved Therapeutic Opportunities (Guido Kroemer) ß utilizing the Immune Response as a Predictor of Outcomes in Breast Cancer (Brian Czerniecki) Break 10:30 am 12:00 pm Session II: Clinical Applications of Immunotherapies in Breast Cancer ß Checkpoint Blockade in Breast Cancer: Lessons Learned and Opportunities going forward (Rita Nanda) ß the potential Role of Vaccines in Breast Cancer: What are the Opportunities (Beth Mittendorf) ß Restoring Th1 Immunity in in HER-2+ Breast Cancer (Heather Han) 12:00 pm 1:00 pm Lunch 1:00 pm 3:00 pm Session III: Combinations of Immune Therapies with Other Standard Therapies ß Combining Chemotherapy with Immune Based Therapies (Leisha Emens) ß Radiation as an Immunologic Weapon in Breast Cancer (Sylvia Formenti) ß Potential of Anti-estrogen Therapies in Combination with Immunotherapy (Hung Khong) ß Utilizing Oncolytic Virus in Combination with Chemotherapy (Hatem Soliman) summary and Concluding Remarks Panel and Audience Discussion on Challenges, Types of Trials, insights, and Future in Breast Cancer Immunology and Immunotherapy.

5 Join Your Colleagues at this Inaugural Conference! Four Ways to Register 1 Register Online Breast_Immune 2 Please photo copy, complete, and Fax the registration form (credit card only) to PleXus Communications, Breast Immune-Oncology Conference: Emerging Opportunities Enhancing Awareness of Clinical Trials First Name Your Degree Institution Mailing Address (check one): q Home q Hopsital q Office Last Name Department City State Zip Phone 3 Scan and the registration form (credit card only) to Registration Fee: (check one) Advance On-site q Physicians $ $ q Fellows $ $ q Nurses, NP, PAs, Pharm, Other $ $ q Industry $ $ There is a cancellation fee of $25 on refunds for any cancellations after September 29, Mail the registraion form with check and credit card info to PleXus Communications 327 Mayland Avenue Moorestown NJ If you have any questions regarding this activity, please contact PleXus Communications: Payment info: (check one) q Check q VISA q MasterCard q Discover q American Express Card Number Expiration Date Security Code Name as it Appears on Credit Card Charge Amount Billing Address on Card (if different from above, zip code required) Signature Yes! Please contact me regarding upcoming medical education opportunities!

6 2150 Highway 35, Suite 250 Sea Girt, NJ Presorted First-Class Mail US Postage PAID TRENTON NJ Permit 185 You Are Invited to Attend the Inaugural CME/CNE Accredited Scientific Conference!

Program Summary Breast Immune-Oncology Conference: Emerging Opportunities-Enhancing Awareness of Clinical Trials

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