Protein Class/Name. Pathways. bat00250, bat00280, bat bat00640, bat00650 bat00270, bat00330, bat00410, bat00480 bat00270, bat00330,
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1 Electronic Supplementary Material (ESI) for Analyst. This journal is The Royal Society of Chemistry 2017 Supplemental Table 2. Proteins Increased in Either Blood or Horizon media Table 2A. Proteins Increased in Spores Produced on Horizon Soil Over Spores Produced on Blood Medium quasi.fdr Protein ID Protein Class/Name Amino Acid Metabolism 4.50E-07 BAS aminobutyrate aminotransferase 3.84E-10 BAS5060 spermidine synthase 2.30E-09 BAS5219 spermidine synthase 6.94E-07 BAS0561 alanine dehydrogenase 5.23E-07 BAS4521 alanine dehydrogenase 8.69E-07 BAS4068 dihydrolipoamide dehydrogenase Membrane, Wall or Surface Proteins KEGG Pathways bat00410, bat00640, bat00650 bat00330, bat00410, bat00480 bat00330, bat00410, bat00480 bat00430 bat00430 Pathway Names or Function (if found in KEGG) Valine, leucine and isoleucine degradation, beta-alanine metabolism to acetyl CoA, Propanoate metabolism, Butanoate metabolism Cysteine and methionine metabolism, Arginine and proline metabolism, beta-alanine metabolism, Glutathione metabolism Cysteine and methionine metabolism, Arginine and proline metabolism, beta-alanine metabolism, Glutathione metabolism Taurine and hypotaurine metabolism Taurine and hypotaurine metabolism BAS5218 agmatinase, putative bat00330 Arginine and proline metabolism 1.40E-10 BAS3891 2,3,4,5-tetrahydropyridine-2- carboxylate N-succinyltransferase, putative bat00300 Lysine biosynthesis bat00630 (TCA cycle), Glycine, serine and threonine metabolism, Valine, leucine and isoleucine degradation, Pyruvate metabolism, Glyoxylate and dicarboxylate metabolism 3.88E-14 BAS3022 ABC transporter, ATP-binding bat02010 ABC-type lipo export system, ATPase 4.80E-22 BAS3023 ABC transporter, permease, putative bat02010 ABC-type antimicrobial peptide transport system, FtsX-like permease family, Defense mechanisms 3.78E-11 BAS0681 phosphate ABC transporter, phosphate-binding, putative bat02010 ABC-2 type transport system 1.10E-06 BAS3475 phosphonate ABC transporter, phosphonate-binding, putative bat02010 ABC-2 type transport system 7.47E-06 BAS0685 AcrB/AcrD/AcrF family transporter 2.84E-10 BAS2122 azoreductase 4.71E-09 BAS1076 catalase Other Enzymes and Proteins BAS2914 catalase, Mn-containing 1.79E-09 BAS3893 CBS domain-containing endonuclease/exonuclease/phosphatas BAS1003 e family 1.69E-09 BAS3851 formamidase 1.92E-07 BAS4914 general stress 20U 1.89E-07 BAS0978 HIT family homogentisate 1,2-dioxygenase, 9.52E-09 BAS0228 putative 1.68E-06 BAS1052 isocitrate lyase 1.80E-11 BAS0850 M20/M25/M40 family peptidase
2 1.95E-12 BAS4591 M42 family peptidase BAS4507 metal-dependent hydrolase 1.89E-07 BAS3884 peptide deformylase 4.56E-09 BAS4071 phosphate butyryltransferase 1.41E-08 BAS3833 prophage LambdaBa02, repressor 7.63E-05 BAS0777 purple acid phosphatase/fibronectin domain-containing 1.07E-08 BAS5239 putative heme peroxidase putative manganese-dependent 6.44E-06 BAS2635 inorganic pyrophosphatase 7.70E-09 BAS0013 pyridoxal biosynthesis lyase PdxS quinone family NAD(P)H 1.29E-05 BAS0798 dehydrogenase 1.75E-14 BAS0047 regulatory SpoVG 3.44E-08 BAS4377 ribonuclease PH 4.80E-22 BAS4293 rrf2 family 2.82E-16 BAS4177 superoxide dismutase, Mn 6.10E-10 BAS0387 tellurium resistance 2.21E-09 BAS4589 thioredoxin family BAS4636 vrrb 9.81E-10 BAS1763 xaa-pro aminopeptidase, putative Fatty Acid Metabolism 1.60E-09 BAS0832 acyl-coa synthetase bat00061, bat BAS4420 enoyl-coa hydratase bat00071 Fatty acid degradation Glycolysis-Pyruvate metabolism- TCA cycle-oxidative phosphorylation 8.56E-06 BAS4661 phosphoenolpyruvate carboxykinase Nucleotide Metabolism 7.70E-09 BAS0006 DNA gyrase subunit A BAS0046 endoribonuclease L-PSP, putative Transcription and Protein translation 1.42E-09 BAS3746 isoleucyl-trna synthetase 2.22E-05 BAS2027 isoleucyl-trna synthetase transcriptional activator TenA, 3.15E-07 BAS0691 putative Sporulation-Germination Proteins Vitamin metabolism bat00620 Fatty acid biosynthesis, Fatty acid degradation (TCA cycle), Pyruvate metabolism 5.04E-09 BAS0696 glycine oxidase bat00730 Thiamine metabolism 5.23E-10 BAS0698 thiazole synthase bat00730 Thiamine metabolism bat00627, 1.47E-08 BAS4244 alkaline phosphatase bat E-10 BAS4021 Aminobenzoate degradation, Folate biosynthesis 6,7-dimethyl-8-ribityllumazine synthase bat00740 Riboflavin metabolism Hypothetical Proteins 1.19E-18 BAS2507 hypothetical 2.84E-10 BAS2513 hypothetical
3 2.58E-09 BAS0474 hypothetical 4.48E-06 BAS4700 hypothetical 1.89E-06 BAS3861 hypothetical 8.87E-06 BAS4191 hypothetical 9.44E-06 BAS3526 hypothetical 7.92E-06 BAS1349 hypothetical 1.61E-05 BAS1620 hypothetical Table 2B. Proteins Increased in Spores from Blood Medium Over Spores Produced in Horizon Soil quasi.fdr Protein ID Protein Class/Name KEGG Pathways Pathway Names or Function (if found in KEGG) Amino Acid Metabolism 3.12E-07 BAS1310 ketol-acid reductoisomerase BAS isopropylmalate synthase asparagine synthetase, glutaminehydrolyzing 1.54E-13 BAS E-08 BAS1825 homoserine dehydrogenase asparagine synthetase, glutaminehydrolyzing 5.75E-10 BAS methyl-2-oxobutanoate 7.41E-14 BAS4067 dehydrogenase, alpha subunit 3-methyl-2-oxobutanoate 3.38E-17 BAS4066 dehydrogenase, beta subunit bat00290, bat01210, bat00770, bat00290, bat01210, bat00770, bat00300, Valine, leucine and isoleucine biosynthesis, 2- Oxocarboxylic acid metabolism, Pantothenate and CoA biosynthesis, Valine, leucine and isoleucine biosynthesis, Pyruvate metabolism, 2-Oxocarboxylic acid metabolism Biosynthesis of secondary metabolites Glycine, serine and threonine metabolism, Cysteine and methionine metabolism, Lysine biosynthesis, Biosynthesis of secondary metabolites Biosynthesis of secondary metabolites Valine, leucine and isoleucine degradation Valine, leucine and isoleucine degradation 6.31E-08 BAS4269 O-acetylserine lyase bat00270 Cysteine and methionine metabolism 2.33E-08 BAS4271 putative AdoMet-dependent methyltransferase - hypothetical bat00270 Cysteine and methionine metabolism 2.26E-16 BAS4879 proline dehydrogenase family bat00330 Arginine and proline metabolism 1.73E-07 BAS3078 D-3-phosphoglycerate dehydrogenase, putative bat00680 Glycine, serine and threonine metabolism, Methane metabolism Membrane, Wall or Surface Proteins BAS4723 ABC transporter, ATP-binding. ABC-type lipo export system bat02010 ABC transporters 2.17E-06 BAS0248 ABC transporter, ATP-binding - binding cassette domain of elongation factor 3 bat02011 ABC transporters 1.39E-12 BAS5281 ABC transporter, ATP-binding - binding cassette domain of elongation factor 3 bat02012 ABC transporters BAS2964 adhesion lipo Structural 1.60E-05 BAS0354 amino acid ABC transporter, ATPbinding bat02012 ABC transporters 1.73E-08 BAS4334 bacitracin ABC transporter ATPbinding, ABC-2 type bat02010 ABC-2 type transport system BAS3140 bacteriocin ABC transporter permease subunit, ABC-2 type transport system ATP-binding bat_m00254 ABC-2 type transport system BAS2597 glycine betaine/l-proline ABC transporter, ATP-binding bat02012 ABC transporters
4 BAS E-06 BAS1102 oligopeptide ABC transporter, oligopeptide-binding, putative bat02010 ABC-2 type transport system oligopeptide ABC transporter, permease bat02010 ABC-2 type transport system 3.44E-10 BAS0237 putative lipo Structural 2.30E-11 BAS5128 rod shape-determining Mbl Structural BAS1048 S-layer, putative Structural 7.81E-09 BAS3642 sugar ABC transporter, ATP-binding bat02010 ABC sugar transport system 9.43E-08 BAS5137 UDP-N-acetylglucosamine 1- carboxyvinyltransferase bat00520, bat00550 Amino sugar and nucleotide sugar metabolism, Peptidoglycan biosynthesis BAS4723 ABC transporter, ATP-binding. ABC-type lipo export system bat02010 ABC transporters Other Enzymes and Proteins 2.73E-05 BAS1263 acetyltransferase 1.60E-05 BAS2680 acetyltransferase aldo/keto reductase family 1.65E-09 BAS0197 oxidoreductase 1.40E-10 BAS3758 cell division FtsA 3.84E-10 BAS2977 chaperone hscc DEAD-box ATP dependent DNA 4.48E-06 BAS1961 helicase 4.65E-12 BAS2195 enoyl-coa hydratase 1.83E-08 BAS5154 F0F1 ATP synthase subunit epsilon fumarylacetoacetate hydrolase family BAS BAS0405 general stress E-14 BAS1936 glycosyl transferase family 1.17E-06 BAS3326 glyoxalase family BAS4338 GTPase ObgE BAS1414 GTP-binding EngA GTP-dependent nucleic acid-binding 2.15E-11 BAS5328 EngD 9.39E-06 BAS3885 HAD superfamily hydrolase BAS2017 HEAT repeat-containing PBS lyase 2.08E-06 BAS4005 lols BAS4593 metallo-beta-lactamase family 6.45E-09 BAS2361 metallo-beta-lactamase/rhodanese-like domain-containing BAS0557 molybdopterin oxidoreductase family 2.39E-19 BAS0147 mrp 1.86E-08 BAS2002 N-acetyltransferase family BAS0591 NorQ, putative phage integrase family site specific 4.20E-05 BAS3556 recombinase 3.81E-12 BAS3863 PhoH family 2.05E-07 BAS3707 phosphatase, putative 2.12E-13 BAS3958 phosphoenolpyruvate- phosphotransferase BAS0838 pre translocase subunit SecA - A diverse family of s involved in ATP-dependent RNA or DNA
5 5.10E E E E E-22 BAS5038 BAS4935 BAS4447 BAS0241 BAS0525 unwinding pre translocase subunit SecA - A diverse family of s involved in ATP-dependent RNA or DNA unwinding pyridine nucleotide-disulphide oxidoreductase recombination and DNA strand exchange inhibitor S1 RNA-binding domain-containing SPFH domain-containing /band 7 family 2.24E-13 BAS5300 superoxide dismutase, Mn 2.24E-06 BAS0390 tellurite resistance, putative TPR/glycosyl transferase domaincontaining BAS E-12 BAS4523 universal stress Fatty Acid Metabolism 3.78E-14 BAS1019 long-chain-fatty-acid--coa ligase 1.23E-14 BAS4876 acetyl-coa acetyltransferase 2.84E-10 BAS E-08 BAS1840 acyl-coa synthetase bat00061, bat00071 bat00071, bat00290, bat00281, bat00362, bat00592, bat00642, Fatty acid biosynthesis, Fatty acid degredation Fatty acid degradation, Valine, leucine and isoleucine degradation, Geraniol degradation, Benzoate degradation, alpha-linolenic acid metabolism, Ethylbenzene degradation, Biosynthesis of secondary metabolites acyl-carrier- S- malonyltransferase bat00061 Fatty acid biosynthesis BAS1017 lipoate- ligase A, putative bat00785 Lipoic acid metabolism 1.68E-14 BAS4840 lipoyl synthase bat00785 Lipoic acid metabolism Glycolysis-Pyruvate metabolism- TCA cycle-oxidative phosphorylation 8.12E-18 BAS0481 formate acetyltransferase bat00640, bat00650 alcohol dehydrogenase, zinccontaining BAS0641 bat00650 Butanoate metabolism 2.83E-14 BAS2111 alcohol dehydrogenase 4.23E-09 BAS1176 dihydrolipoamide succinyltransferase BAS2585 dihydrolipoamide dehydrogenase 1.13E-15 BAS2376 acetoacetyl-coa synthase BAS E-07 BAS2587 TPP-dependent acetoin dehydrogenase E1 alpha-subunit TPP-dependent acetoin dehydrogenase E1 beta-subunit bat00071, bat00350, bat00625, bat00626 bat00310 bat00630 bat00640, bat00680, bat00620 Pyruvate metabolism, Propanoate metabolism, Butanoate metabolism Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Chloroalkane and chloroalkene degradation, Naphthalene degradation Citrate cycle (TCA cycle), Lysine degradation (TCA cycle), Glycine, serine and threonine metabolism, Valine, leucine and isoleucine degradation, Pyruvate metabolism, Glyoxylate and dicarboxylate metabolism Glycolysis / Gluconeogenesis, Pyruvate metabolism, Propanoate metabolism, Methane metabolism (TCA cycle), Pyruvate metabolism (TCA cycle), Pyruvate metabolism
6 bat E-10 BAS2762 malate:quinone oxidoreductase bat00620 acetyl-coa hydrolase/transferase 8.17E-07 BAS1726 family bat oxoglutarate ferredoxin 2.74E-06 BAS3622 oxidoreductase subunit beta bat00020 Citrate cycle (TCA cycle) branched-chain alpha-keto acid 5.43E-05 BAS2586 dehydrogenase subunit E2 Citrate cycle (TCA cycle), Pyruvate metabolism Citrate cycle (TCA cycle), Pyruvate metabolism, Butanoate metabolism (TCA cycle), Pyruvate metabolism, 7.90E-06 BAS4773 gluconate 2-dehydrogenase bat00030 Pentose phosphate pathway 2.75E-09 BAS3997 phosphopentomutase bat00030 Pentose phosphate pathway 2.16E-05 BAS0668 quinol oxidase, subunit I bat00190 Oxidative phosphorylation 2.19E-15 BAS0669 quinol oxidase, subunit II bat00190 Oxidative phosphorylation UTP-glucose-1-phosphate 1.09E-11 BAS4789 uridylyltransferase bat00040, bat BAS4869 L-lactate dehydrogenase Nucleotide Metabolism bat00640 Glycolysis / Gluconeogenesis, Cysteine and methionine metabolism, Pyruvate metabolism, Propanoate metabolism BAS3995 pyrimidine-nucleoside phosphorylase bat00240 Pyrimidine metabolism BAS0029 thymidylate kinase bat00240 Pyrimidine metabolism anaerobic ribonucleoside triphosphate bat00230, BAS3398 reductase bat00240 Purine metabolism, Pyrimidine metabolism 3.26E-12 BAS3676 uridylate kinase bat00240 Pyrimidine metabolism BAS5164 uracil phosphoribosyltransferase bat00240 Pyrimidine metabolism Transcription and Protein translation 1.36E-09 BAS S ribosomal S1 3.76E-07 BAS S ribosomal S E-07 BAS4472 threonyl-trna synthetase trna (uracil-5-)-methyltransferase 2.30E-11 BAS3683 Gid 2.70E-05 BAS4291 trna-specific 2-thiouridylase MnmA 4.15E-10 BAS4936 tyrosyl-trna synthetase 8.09E-11 BAS0306 aspartyl/glutamyl-trna amidotransferase subunit A 2.18E-12 BAS0307 aspartyl/glutamyl-trna amidotransferase subunit B 3.02E-05 BAS4784 glycyl-trna synthetase BAS3670 prolyl-trna synthetase 1.34E-05 BAS1014 LacI family sugar-binding transcriptional regulator BAS4013 LacI family sugar-binding transcriptional regulator Sporulation-Germination Proteins 3.44E-08 BAS5185 stage 0 sporulation F 2.17E-05 BAS5332 stage 0 sporulation J BAS0731 stage V sporulation R 1.20E-08 BAS3654 dipicolinate synthase subunit A Vitamin Biosynthesis 5.07E-08 BAS4023 biotin synthase bat00780 biotin synthesis
7 6.40E-06 BAS4027 dithiobiotin synthetase bat00780 biotin synthesis 1.82E-05 BAS4328 cysteine desulfurase bat00730 Thiamine metabolism 7.99E-06 BAS5266 pyridoxal kinase bat00750 Vitamin B6 metabolism Hypothetical Proteins BAS0289 hypothetical BAS4934 hypothetical BAS2158 hypothetical BAS3372 hypothetical BAS1250 hypothetical BAS2691 hypothetical BAS0997 hypothetical 6.40E-07 BAS3810 hypothetical BAS1377 hypothetical 2.67E-05 BAS2950 hypothetical BAS4448 hypothetical 2.33E-07 BAS1468 hypothetical 4.23E-09 BAS2803 hypothetical 2.16E-05 BAS3307 hypothetical 5.98E-05 BAS1927 hypothetical 4.87E-06 BAS0915 hypothetical 1.24E-05 BAS0394 hypothetical 4.67E-06 BAS3621 hypothetical 5.69E-07 BAS0084 hypothetical 1.36E-09 BAS3590 hypothetical 3.75E-14 BAS2273 hypothetical 1.75E-14 BAS2829 hypothetical 4.67E-17 BAS0518 hypothetical 1.45E-20 BAS2554 hypothetical
Protein Class/Name. Pathways. bat00250, bat00280, bat00410, bat00640, bat bat00270, bat00330, bat00410, bat00480
Electronic Supplementary Material (ESI) for Analyst. This journal is The Royal Society of Chemistry 2017 Supplemental Table 1. Proteins Increased in Either Soil or Laboratory media Table 1A. Proteins Increased
Protein Class/Name KEGG Pathways
Electronic Supplementary Material (ESI) for Analyst. This journal is The Royal Society of Chemistry 2017 Supplemental Table 4. Proteins Increased in Either Soil medium at 37 o C and 25 o C Table 4A. Proteins
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