Table S9A: List of taurine regulated genes in Bp K96243 Chr 1 (up regulated >=2 fold) Cluster no GENE ID Start Stop Strand Function

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1 Table S9A: List of taurine regulated genes in Bp K96243 Chr 1 (up regulated >=2 fold) Cluster no GENE ID Start Stop Strand Function 1 BPSL LrgA family BPSL hypothetical BPSL flagellar basal body BPSL flagellar motor switch BPSL probable flagellar motor switch BPSL flagellar BPSL flagellar biosynthetic BPSL flagellar biosynthesis BPSL flagellar biosynthetic 2 BPSL putative GMC oxidoreductase BPSL putative flagellar hook length control BPSL flagellar flij BPSL flagellum specific ATP synthase BPSL flagellar assembly BPSL flagellar motor BPSL flagellar M ring BPSL flagellar hook basal body complex BPSL flagellar BPSL hypothetical BPSL hypothetical BPSL putative export system BPSL hypothetical 3 BPSL hypothetical BPSL putative flagella synthesis BPSL putative negative regulator of flagellin synthesis BPSL flagellar basal body P ring biosynthesis BPSL putative flagellar basal body rod BPSL flagellar basal body rod BPSL putative basal body rod modification BPSL flagellar hook BPSL flagellar basal body rod BPSL flagellar basal body rod BPSL flagellar L ring precursor BPSL flagellar P ring precursor BPSL putative peptidoglycan hydrolase BPSL hypothetical

2 BPSL flagellar hook associated BPSL putative flagellar hook associated BPSL putative permease 4 BPSL metallo beta lactamase superfamily 5 BPSL DNA polymerase III subunit alpha BPSL hypothetical BPSL putative transporter BPSL putative fatty acid desaturase BPSL putative diaminobutyrate 2 oxoglutarate aminotransferase BPSL hypothetical BPSL hypothetical BPSL ABC transport system ATP binding BPSL hypothetical BPSL hypothetical BPSL hypothetical BPSL hypothetical BPSL hypothetical BPSL putative AMP binding enzyme BPSL putative pyridoxal dependent decarboxylase BPSL hypothetical BPSL hypothetical BPSL hypothetical BPSL hypothetical BPSL putative acyl carrier BPSL hypothetical BPSL putative AMP binding enzyme 6 BPSL hypothetical BPSL putative polysaccharide biosynthesis BPSL putative glycosyl transferase BPSL putative mannose 1 phosphate guanylyltransferase BPSL hypothetical BPSL putative glycosyl transferase BPSL PAP2 superfamily BPSL fis family regulatory BPSL hypothetical BPSL glycosyl hydrolase family

3 BPSL hypothetical BPSL hypothetical BPSL putative acyl CoA dehydrogenase BPSL acyl carrier BPSL hypothetical BPSL hypothetical BPSL putative sugar transferase BPSL putative polysaccharide biosynthesis/export BPSL glycosyl transferase group 1 BPSL hypothetical 7 BPSL putative RND family acriflavine resistance A precursor BPSL putative RND family acriflavine resistance BPSL outer membrane efflux 8 BPSL cobalamin biosynthesis CbiG BPSL cob(i)yrinic acid a,c diamide adenosyltransferase BPSL cobyrinic acid A,C diamide synthase BPSL putative siderophore biosynthesis related BPSL putative iron uptake receptor precursor BPSL putative L ornithine 5 monooxygenase BPSL putative siderophore related non ribosomal peptide synthase BPSL BPSL putative siderophore related no ribosomal peptide synthase putative siderophore biosynthesis related ABC transport BPSL hypothetical BPSL putative iron transport related exported BPSL putative iron transport related membrane BPSL BPSL putative iron transport related membrane putative iron transport related ATP bidning BPSL hypothetical BPSL hypothetical BPSL RNA polymerase sigma 70 factor

4 9 BPSL putative lipo BPSL putative fimbriae related BPSL putative fimbriae assembly chaperone BPSL hypothetical BPSL hypothetical BPSL hypothetical 10 BPSL putative multidrug resistance 11 BPSL putative acyltransferase BPSL hypothetical BPSL family M1 unassigned peptidase BPSL hypothetical BPSL hypothetical BPSL putative bacteriocin secretion BPSL colicin V processing peptidase BPSL putative outer membrane bacteriocin efflux 12 BPSL ,10 methylenetetrahydrofolate reductase BPSL hypothetical BPSL S adenosyl L homocysteine hydrolase BPSL flagellar biosynthesis sigma factor FliA BPSL flagellar biosynthesis FlhG BPSL flagellar biosynthesis BPSL flagellar biosynthesis BPSL flagellar biosynthetic FlhB BPSL hypothetical BPSL Gly/Ala/Ser rich lipo BPSL hypothetical BPSL chemotaxis CheZ BPSL chemotaxis CheY BPSL chemotaxis specific methylesterase BPSL putative chemotaxis BPSL chemotaxis methyltransferase BPSL methyl accepting chemotaxis I BPSL chemotaxis CheW BPSL chemotaxis two component sensor kinase CheA BPSL chemotaxis two component response regulator CheY1 BPSL flagellar motor

5 BPSL flagellar motor BPSL flagellar regulon master regulator subunit FlhC BPSL transcriptional activator FlhD BPSL S ribosomal S21 BPSL flagellin BPSL flagellar hook associated BPSL hypothetical BPSL putative TPR domain BPSL putative transferase BPSL putative keto/oxo acyl ACP synthase BPSL putative acyl carrier BPSL putative keto/oxo acyl ACP synthase BPSL putative short chain dehydrogenase BPSL putative acetyltransferase BPSL Rieske [2Fe 2S] domain BPSL hypothetical Table S9B: List of taurine regulated genes in Bp K96243 Chr 2 (up regulated >=2 fold) Cluster no GENE ID Start Stop Strand Function 1 BPSS alpha ketoglutarate permease BPSS C4 dicarboxylate transport sensor kinase BPSS C4 dicarboxylate transport transcriptional response regulator 2 BPSS hypothetical BPSS hemin ABC transport system, ATP binding BPSS hemin ABC transport system, membrane BPSS hemin transport system, substrate binding BPSS hemin ABC transport system related BPSS exported heme receptor 3 BPSS fatty acid CoA ligase BPSS malonyl CoA acyl carrier BPSS hypothetical BPSS fatty acid biosynthesis related CoA ligase BPSS diaminopimelate decarboxylase BPSS hypothetical BPSS ketol acid reductoisomerase BPSS multifunctional polyketide peptide syntase

6 BPSS aldehyde dehydrogenase BPSS hypothetical BPSS peptide synthase regulatory BPSS hypothetical BPSS multifunctional polyketide peptide syntase BPSS LuxR family transcriptional regulator BPSS lipo BPSS monooxygenase BPSS ABC transport system, ATP binding BPSS ACB transport system, membrane BPSS monooxygenase BPSS hypothetical 4 BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS biopolymer transport BPSS bipolymer transport BPSS TonB like transport BPSS bacterioferritin ferredoxin BPSS glutamate racemase BPSS bacterioferritin 5 BPSS acetyl CoA hydrolase/transferase BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS ATPase BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical

7 BPSS lipo BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hypothetical BPSS hydroxydecanoyl ACP:CoA transacylase BPSS UDP glucoronosyl and UDP glucosyl transferase BPSS transport BPSS hypothetical BPSS outer membrane efflux BPSS HlyD family secretion BPSS glycosyl hydrolase 6 BPSS salicylate biosynthesis isochorismate synthase BPSS chorismate mutase BPSS pyochelin biosynthetic BPSS salicyl AMP ligase BPSS AraC family regulatory BPSS pyochelin synthetase BPSS pyochelin synthetase BPSS pyochelin biosynthetic 7 BPSS catalase precursor 8 BPSS HlyD family efflux pump BPSS outer membrane efflux BPSS dtdp rhamnosyl transferase BPSS efflux/sugar transport/multidrug resistance BPSS rhamnosyltransferase BPSS fatty acid biosynthetic 9 BPSS permease component of taurine ABC transporter BPSS ATP binding component of taurine ABC transporter BPSS periplasmic component of taurine ABC transporter alpha ketoglutarate dependent taurine BPSS dioxygenase

8 10 BPSS type IV pilus biosynthesis BPSS hypothetical BPSS major pilin subunit BPSS type IV pilus biosynthesis BPSS type IV pilus biosynthesis BPSS hypothetical BPSS type IV pilus biosynthesis BPSS type IV pilus biosynthesis BPSS type IV pilus biosynthesis BPSS twitching motility BPSS secretion BPSS probable two component system response regulator BPSS probable two component system sensor kinase 11 BPSS hypothetical BPSS probable non ribosomal peptide synthetase BPSS probable non ribosomal peptide synthetase BPSS probable non ribosomal peptide synthetase BPSS hypothetical 12 BPSS hypothetical BPSS hydroxy 2 ketovalerate aldolase BPSS acetaldehyde dehydrogenase BPSS thioesterase BPSS branched chain amino acid aminotransferase BPSS transferase BPSS non ribosomal peptide synthesis thioesterase BPSS non ribosomal peptide synthase related BPSS hypothetical BPSS non ribosomal peptide synthase 13 BPSS catalase HPII 14 BPSS permease BPSS ABC transporter ATP binding BPSS flavin binding monooxygenase like BPSS cytochrome P450 family BPSS multi domain beta keto acyl synthase BPSS acyl transferase

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