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1 s fr persnal care made fr me s

2 A challenge fr every frmulatr is selecting the right system that delivers an effective level f prtectin against. The family f s frm Ashland pecialty ngredients ffers a variety f s fr skin, sun and hair care prducts. Available in five categries prgressive, nature-identical, armatic, classic and bsters these versatile prducts are fast-acting and lng-lasting t help prduct manufacturers cmply with regulatry requirements arund the wrld. Featuring widely trusted brands such as ptiphen, Germall, Germaben, Rknsal and thers, ur s are supprted by Ashland s glbal technical expertise and service s yu can frmulate with cnfidence knwing we have a system that meets yur preservatin requirements. T learn mre abut hw Ashland can help prtect yur persnal care prducts, cntact ne f ur experts tday. prgressive s As persnal care prduct manufacturers sell t an increasingly glbal client base, they need apprved ingredients t easily navigate regulatry hurdles. Ashland s family f prgressive s featuring the ptiphen and Rknsal prduct lines is apprved fr use in all majr markets, cmpatible with a variety f frmulatins and nt based n paraben, frmaldehyde r halgens. Effective against gram-psitive and gram-negative bacteria, yeast and mld, they ffer excellent heat stability, wrk acrss a wide p windw and are easily slubilized in water. prgressive range Antimicrbial Activity Prfile Applicatins ptiphen ptiphen aprylyl Glycl lear t pale straw liquid n-paraben n-fa-dnr n-algen Mld Brad-spectrum Effective ver p f 4 t 8 kin are Trade ame air are EMEA A Descriptin/ ame Frm tructure Use Levels Prductin p t t be used fr % a tes ptiphen 200 ptiphen 200 aprylyl Glycl lear t pale straw liquid Brad-spectrum Effective ver p f 4 t % a ptiphen 300 ptiphen 300 aprylyl Glycl lear t pale straw liquid Brad-spectrum additinal fungicidal prtectin may be needed in difficult frmulatins Effective ver p f 4 t % a ptiphen Plus ptiphen Plus aprylyl Glycl (and) rbic Acid lear t pale straw liquid Brad-spectrum deal fr slightly acidic persnal care prducts Effective p range up t % 80 up t 6.0 b Rknsal BP ptiphen BP Prpylene Glycl (and) Benzic Acid (and) rbic Acid Micrbistatic spectrum f bacteria, mld and yeast Effective up t p % 80 up t Rknsal D ptiphen D Benzic Acid (and) Dehydracetic Acid yellwish Micrbistatic spectrum f bacteria, mld and yeast Effective up t p % 80 up t 6.4 3, 4 a ptiphen P ptiphen P Phenxyethanl Micrbistatic activity Wide p 3 t 10, usually in cmbinatin with ther actives up t 1% a +++ highly recmmended, ++ recmmended, + suitable, - nt recmmended 2

3 ptiphen P platfrm ptimizing the delivery f nn-alchl s is essential t the viability f next-generatin systems. Ashland s ptiphen P platfrm is the first technlgy platfrm withut alchlic antimicrbials, based n an ptimized delivery system. The delivery system serves t stensibly maximize efficacy withut interfering r destabilizing csmetic frmulatins, such as emulsins. All f the prducts ffered within the ptiphen P platfrm address tday s demands fr cst-efficient s that fllw natural ingredient trends. ptiphen DP ffers brad spectrum prtectin and cmplies with ne r all f the fllwing labels: Bra Miljöval (Gd Envirnmental hice), rdic Eclabel (wan) and EU Eclabel (Flwer) 2014/893/EU. ptiphen DLP prvides antifungal bsting at lwer use levels. When used at higher dsages full prtectin can be achieved. ptiphen P platfrm Antimicrbial Activity Prfile Applicatins n-paraben ptiphen DP ptiphen DP Prpylene arbnate (and) Benzic Acid (and) Dehydracetic Acid (and) Prpanedil n-fa-dnr n-algen Micrbistatic spectrum f activity, in sme frmulatins additinal bster is needed Effective up t p 6.0 st efficient ptimized delivery system withut alchlic antimicrbials Mld kin are Trade ame air are EMEA A Descriptin/ ame Frm tructure Use Levels Prductin % 80 up t 6.0 p t t be used fr 4, 9 tes ptiphen DLP ptiphen DLP Prpylene arbnate (and) Dehydracetic Acid Antifungal bsting activity at lw levels; full antimicrbial spectra at high levels Effective up t p 6.4. st efficient based n nature identical active ingredient ptimized delivery system withut alchlic antimicrbials % 80 up t 6.4 4, highly recmmended, ++ recmmended, + suitable, - nt recmmended 4

4 nature-identical s The natural mvement cntinues t drive cnsumer buying habits, s it s n surprise that marketers als harbr a preference fr all things green. That s why Ashland s nature-identical s are ideal s fr prducts aimed at the ec-aware cnsumer. EERT-, ATRUE-, M- and BD-cmpliant Rknsal and ptiphen B and BB-type s are synthetic versins f naturally ccurring substances with excellent efficacy and glbal apprval fr rinse-ff and leave-n applicatins. These effective s supprt a variety f natural persnal care prducts. nature-identical range Antimicrbial Activity Prfile Applicatins ptiphen BD ptiphen BB-W t ptiphen BB-W Benzyl Alchl (and) Benzic Acid (and) Dehydracetic Acid Benzyl Alchl (and) Aqua (Water) (and) dium Benzate (and) Ptassium rbate yellwish Yellwishbrwnish liquid n-paraben n-fa-dnr n-algen Mld Micrbistatic spectrum f bacteria, mld and yeast Effective up t p 6.4 ature-identical cmbinatin Effective against gram-psitive and gram-negative bacteria, yeast and mld Effective up t p 5.4 ature-identical cmbinatin kin are Trade ame air are EMEA A Descriptin/ ame Frm tructure Use Levels Prductin % 80 up t % 80 up t 5.4 p t t be used fr tes 3, 4 c 2 c Rknsal B ptiphen B dium Benzate (and) Ptassium rbate Yellw t light brwn a 3 K Micrbistatic spectrum f activity Effective up t p 5.4 ature-identical cmbinatin % 80 up t c Rknsal BB- ptiphen BB- Benzyl Alchl (and) Glycerin (and) Benzic Acid (and) rbic Acid lrless liquid Effective against grampsitive and gram-negative bacteria, yeast and mld Effective up t p 5.4 Glbal use ature-identical cmbinatin Validated by M and ATRUE % 80 up t c +++ highly recmmended, ++ recmmended, + suitable, - nt recmmended 6

5 armatics with antimicrbial prperties Grwing cnsumer demand fr multifunctinal and nature-identical ingredients is giving rise t new prduct brands and new persnal care frmulatins. Addressing these trends, Ashland ffers frmulatrs with a range f s thrugh its narm armatic prduct line, a frtifying system cntaining naturally derived and nature-identical ingredients that add mild flwery fragrance t persnal care frmulatins and deliver brad antimicrbial prtectin as an additinal effect. n additin, narm P-2 displays gd frmulatin cmpatibility and des nt impart clr change n final frmulatins. The naturally derived emulsifier systems and the cntained bster can enhance misturizing prperties in the final frmulatin. narm P-2 cnfrms t eclabels such as Bra Miljval (Gd envirnmental chice), rdic Eclabelling (wan) and EU Eclabel (Flwer) 2014/893/E. narm P and narm P-2 armatic are ffering a gentle rse-like arma that heightens the characteristic f the end prducts. armatic range Antimicrbial Activity Prfile Applicatins n-paraben n-fa-dnr n-algen Trade ame air are kin are Prductin EMEA A Leavefff Rinse- Leave- Rinse- Use ame Descriptin/Frm Levels p % narm B armatic narm B armatic Phenylprpanl, umulus Lupulus (ps) Extract ature-derived and nature-identical fragrance additive Mld Mild flwery spicy fragrance, cntaining naturally derived and nature identical ingredients that prvides brad-spectrum prtectin mplements arma f final prduct Effective p range 4 8 t t be used fr tes narm P armatic narm P armatic Phenethyl Alchl (and) aprylyl Glycl (and) Trideceth-8 ature-identical fragrance additive in glyclic Mild rse-like arma Armatic ingredient that prvides brad-spectrum prtectin mplements arma f final prduct Effective p range % narm P-2 armatic narm P-2 armatic Phenethyl Alchl (and) aprylyl Glycl (and) Prpanedil (and) Plyglyceryl-4 Laurate/ ebacate (and) Plyglyceryl-6 aprylate/ aprate (and) Aqua (Water) ature-identical fragrance additive with naturally derived emulsifier system Mild rse-like arma, cntaining naturally derived and nature identical ingredients Armatic ingredient that prvides brad-spectrum prtectin mplements arma f final prduct Effective p range % highly recmmended, ++ recmmended, + suitable, - nt recmmended 8

6 classic s Tried and true, Ashland s classic s deliver efficient antimicrbial pwer t a wide variety f persnal care prducts. Balanced, synergistic and basting brad-spectrum prtectin, Germaben, Germall, uttcide, Liquagard, LiquaPar and Rknsal are cmpatible with many ther csmetic ingredients. Apprved fr use in mst cuntries, the family f classic s are effective at lw dses and can be used t blster ther s. classic range Antimicrbial Activity Prfile Applicatins Germaben Germaben -E Germall 115 Germall Germall Plus Germall 115 Germall Germall Plus Prpylene Glycl (and) Diazlidinyl Urea (and) Prpylparaben midazlidinyl Urea Diazlidinyl Urea Diazlidinyl Urea (and) dprpynyl Butylcarbamate White, free-flwing hygrscpic pwder White, free-flwing hygrscpic pwder White, free-flwing hygrscpic pwder 2 n-paraben n-fa-dnr n-algen Mld Effective ver brad p range Very effective against gram-psitive and gram-negative bacteria Acts synergistically with ther s Effective ver brad p range Brad-spectrum gram-psitive and gram-negative bacteria ynergistic with ther s Effective ver brad p range Brad-spectrum antimicrbial activity Effective ver brad p range kin are Trade ame air are EMEA A Descriptin/ ame Frm tructure Germaben Brad-spectrum R Germaben -E R= 3 gram-psitive and gram-negative Use Levels Prductin % % % % 50 p t t be used fr tes , 6 d Germall Plus Germall Plus Prpylene Glycl (and) Diazlidinyl Urea (and) dprpynyl Butylcarbamate Brad-spectrum antimicrbial activity Effective ver brad p range % , 6 d t Liquagard Butylene Glycl (and) dprpynyl Butylcarbamate Effective fungicide Wrks ver wide p range Temperature stable mpatible with brad range f raw materials including surfactants and prteins % , 6 d ptiphen MT ptiphen MT Aqua (Water) (and) Methylisthiazlinne lrless t yellwish Effective against gram-psitive and gram-negative bacteria Effective between p 2 and % , 12, 13 ptiphen MT Plus ptiphen MT Plus Aqua (Water) (and) Methylisthiazlinne (and) Phenethyl Alchl (and) PPG-2 Methyl Ether lrless t yellwish Brad-spectrum Effective between p 2 and % , 12, 13 ptiphen MT Ultra ptiphen MT Ultra Aqua (Water) (and) Methylisthiazlinne (and) Phenylprpanl (and) Prpylene Glycl lrless t yellwish 3 2 Brad-spectrum Effective between p 2 and % , 12, highly recmmended, ++ recmmended, + suitable, - nt recmmended 10

7 classic range LiquaPar ME n-paraben n-fa-dnr n-algen Antimicrbial Activity Prfile Ethylparaben (and) aprylyl Glycl yellwish 3 Gram+/ Gram- Mld Applicatins kin are Trade ame air are EMEA A Descriptin/ ame Frm tructure t Prvides similar efficiency t Use Levels traditinal paraben cmbinatins Effective ver brad p range % Prductin p t t be used fr tes e LiquaPar il LiquaPar il sprpylparaben (and) sbutylparaben (and) Butylparaben R R=(3)2 (2)33 2(3)2 lvent-free Effective against gram-psitive Effective ver brad p range % e LiquaPar ptima LiquaPar ptima sprpylparaben (and) sbutylparaben (and) Butylparaben R= 3 ( R 3 ) 2 2( 3) 2 ( 2) 3 3 Brad-spectrum Effective ver brad p range % e LiquaPar PE LiquaPar PE sprpylparaben (and) sbutylparaben (and) Butylparaben R= ( 3 ) 2 ( 2 ) ( 3 ) 2 R Brad-spectrum Effective ver brad p range % e Rknsal J t Phenxyethanl (and) dprpynyl Butylcarbamate Effective fungicide Wrks ver wide p range Temperature stable mpatible with brad range f raw materials including surfactants and prteins % , 6 d Rknsal K-4 Rknsal LJ-1 t t Prpylene Glycl (and) Benzyl Alchl (and) Methylchlristhiazlinne (and) Methylisthiazlinne Benzyl Alchl (and) 2-Brm-2-itrprpane- 1,3-Dil (and) dprpynyl Butylcarbamate (and) Deceth-8 (and) PPG-2 Methyl Ether yellwish Light yellw t light brwn l - + Br Brad-spectrum Me Fast-acting Effective up t p 8 max. Brad-spectrum against fungi and yeast bacteria, with enhanced perfrmance Fast-acting Effective up t p 7 max % % max. 1, 7, 12 7 max. 5, 6 d, f Rknsal MEP LiquaPar MEP Ethylparaben (and) Prpylparaben yellwish R R= Brad-spectrum Effective ver brad p range % e Rknsal PB-4 LiquaPar P Ethylparaben (and) Prpylparaben (and) Butylparaben R R= ( 2) 3 3 Brad-spectrum Effective ver brad p range % e Rknsal -1 LiquaGard -1 Methylchlristhiazlinne (and) Methylisthiazlinne lrless t yellw 3 Brad-spectrum f activity Fast-acting at lw use-levels 40 8 max. 1, 7, 12 Rknsal E-2 t 2-Brm-2-itrprpane- 1,3-Dil (and) Ethylparaben (and) etrimnium Brmide (and) PPG-2 Methyl Ether yellw t brwn - + Br + Br - Brad-spectrum bacteria, fungi and yeast Fast-acting Effective up t p 7 max % 40 7 max. f uttcide A uttcide A dium ydrxymethylglycinate lear t pale yellw - a + Brad-spectrum preservatin Lng histry f use fr efficacy Fast-acting Effective p % g +++ highly recmmended, ++ recmmended, + suitable, - nt recmmended 12

8 bsters Dils can influence the verall micrbial stability due t their water binding prperties. They are widely used in skin care, hair care, wet wipes, tiletries and clr csmetics. With their misturizing and slubilizing prperties they are cnsidered t be multifunctinal. Their neutral smell and wide p tlerance makes them suitable fr many applicatins. n emulsins the Dils shuld be added at the pst-emulsificatin stage, t enhance their availability at the water/il interface. Preservative Bster Range Applicatins Trade ame air are kin are Prductin EMEA A Descriptin/ Leavefff Levels matrix) p Rinse- Leave- Rinse- Use by ame Frm tructure ptiphen D ptiphen aprylyl Glycl t waxy Misturizing agent % D lvent fr active ingredients bster umectant bster Preservative bster t t be used fr tes ptiphen D bster ptiphen D bster 1,2-exanedil Misturizing agent lvent fr active ingredients umectant Preservative bster % highly recmmended, ++ recmmended, + suitable, - nt recmmended As f December 2017, the infrmatin presented here is accurate and factual t the best f ur knwledge, based n data. Fr cuntry-specific details, please cntact yur technical service representative. 1 Japan: t permitted in prducts that cme int cntact with mucus membranes. 2 n prducts with p higher than n prducts with p higher than E.U.: t fr use in aersls. 5 E.U.: t fr ral hygiene and lip care prducts; t t be used in prducts fr children < 3 years except in bath prducts/shwer gels and shamps; t t be used in bdy ltin and bdy cream. 6 U.. and Japan: t fr use in aersls. 7 Japan: t permitted in leave-n prducts. 8 Japan: t permitted in prducts that cme int cntact with mucus membranes. Required warning: huld nt be used by infants r by peple wh are hypersensitive t frmaldehyde. 9 n prducts with p higher than E.U.: t t be used in leave-n prducts designed fr applicatin t the nappy area f children yunger than 3 years. Fr leave-n prducts nt intended t be applied t the nappy area f children yunger than 3 years, required warning D nt use n the nappy area. 11 E.U.: t permitted due t isprpylparaben and isbutylparaben cntent. 12 E.U.: Apprved nly fr rinse-ff prducts. 13 E.U.: Recmmended use levels exceed maximum allwed cncentratin f Methylisthiazlinne (frm 27 January 2018 fr prducts being placed n the market; frm 27 April 2018 fr prducts n the market). a ninic surfactants might decrease efficacy. b Enhanced efficacy cmpared t ptiphen in slightly acidic prducts. c The ingredients cntained fulfill recmmendatins fr use in atural smetic Prducts like BD, M, ATRUE and EERT. d E.U.: Apprved cncentratins fr specific applicatins shuld be verified. e Prteins, nninic and highly ethxylated surfactants might decrease efficiency. f D nt frmulate with DEA-salts (secndary amines and amides) r triethanlamine, nitrsamine frmatin might ccur. g Avid catinics and citrus perfumes. itrus perfumes may lead t disclratin. FA = Frmaldehyde 14

9 REGAL ETER RT AMERA Bridgewater, J UA Tel: LAT AMERA ã Paul, Brazil Tel: EURPE Barcelna, pain Tel: Fax: AA PAF ingapre Tel: Fax: hanghai, P.R. hina Tel: Fax: MDDLE EAT, AFRA, DA Turkey Tel: Fax: The infrmatin cntained in this brchure and the varius prducts described are intended fr use nly by persns having technical skill and at their wn discretin and risk after they have perfrmed necessary technical investigatins, tests and evaluatins f the prducts and their uses. ertain end uses f these prducts may be regulated pursuant t rules r regulatins gverning medical devices, drug uses, r pesticidal r antimicrbial uses. t is the end user s respnsibility t determine the applicability f such regulatins t its prducts. All statements, infrmatin, and data presented herein are believed t be accurate and reliable, but are nt t be taken as a guarantee f fitness fr a particular purpse, r representatin, express r implied, fr which seller assumes legal respnsibility. freedm t use any patent wned by Ashland, its subsidiaries, r its suppliers is t be inferred. ashland.cm/persnalcare Registered trademark, Ashland r its subsidiaries, registered in varius cuntries Trademark, Ashland r its subsidiaries, registered in varius cuntries 2017, Ashland / P

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