2014 Descriptive Vet Path Course. Gross Exam #1

Transcription

1 2014 Descriptive Vet Path Course Gross Exam #1

2 2014 DESCRIPTIVE VETERINARY PATHOLOGY COURSE GROSS EXAM #1 1. Tissue from a mouse. Name the condition: Ringtail Cause: Low humidity 2. Tissue from an ox. Morphologic Diagnosis: Femoral osteopetrosis Pathogenesis: Nonfunctional ruffled border on macrophages => no resorption of mineralized primary spongiosa=> no remodeling of bone Name another possible lesion in this animal: Brachygnathia, oligo- or anodontia 3. Tissue from a dog. Morphologic Diagnosis: Orbital meningioma 4. Tissue from a calf. Morphologic Diagnosis: Segmental necrohemorrhagic enteritis Cause: Clostridium perfringens type C 5. Tissue from a water moccasin (a.k.a cottonmouth, a North American viper) Morphologic Diagnosis: Diffuse proliferative and catarrhal gastritis Cause: Cryptosporidium serpentis 6. Tissue from a foal. Morphologic Diagnosis: Segmental catarrhal enteritis Cause: Parascaris equorum Name a possible sequela: Impaction or ulceration due to linear foreign body 7. Tissue from a cat. Morphologic Diagnosis: Cranial meningioma with pressure atrophy of underlying cerebrum 8. Tissue from a turkey. Morphologic Diagnosis: Diffuse unilateral fibrinonecrotic pneumonia Name the Condition: Ornithobacterium rhinotracheale (P.multocida OK) 9. Tissue from a dog. Pathogenesis: Hepatic macronodular regeneration and fibrosis (cirrhosis) =>portal hypertension=> development of vestigial (acquired) shunts

3 10. Tissue from a sheep. Give two morphologic diagnoses: Focal unilateral cerebral coenurus; bilateral hydrocephalus Cause: Coenurus cerebralis Name the condition: Gid 11. Tissue from a sea lion. Morphologic Diagnosis: Diffuse chronic lymphoplasmacytic nephritis Cause: Leptospira icterohemorrhagica (other Lepto species OK) 12. Tissue from a rabbit. Morphologic Diagnosis: Diffuse fibrinosuppurative pleuropneumonia Cause: Pasteurella multocida Name two additional lesions in this animal: Suppurative otitis media, atrophic rhinitis, suppurative metritis 13. Tissue from a dog. Pathogenesis: Renal failure=>mineralization of alveolar basement membranes and vessel walls=>severe pulmonary edema=> uremic pneumonitis 14. Tissue from a calf. Morphologic Diagnosis: Multifocal to coalescing proliferative and ulcerative dermatitis Cause: Ovine poxvirus (sheeppox), bovine herpesvirus-2 Name the disease: Lumpy skin disease (pseudolumpy skin if chose bovine herpesvirus-2) 15. Tissue from a chicken. Morphologic Diagnosis: Persistent right oviduct 16. Tissue from a dog Morphologic Diagnosis: Multifocal to coalescing granulomatous pneumonia Cause: Blastomyces dematitidis (other dimorphic fungi OK) 17. Tissue from a skunk: Etiologic diagnosis: Sinonasal skrjabinguliasis (Skrjabingylus chitwoodorum) 18. Tissue from an ox. Pathogenesis: Ingestion of L-shaped wire=>penetration of reticulum into pericardial sac=>transfer of bacteria=>chronic fibrinosuppurative pericarditis and epicarditis ( hardware disease )

4 19. Tissue from a sheep. Morphologic Diagnosis: Diffuse hepatic necrosis Cause: Copper toxicosis Name another lesion in this animal: Hemolytic anemia; acute tubular necrosis of the kidney 20. Tissue from a pig. Morphologic Diagnosis: Diffuse lymphocytic interstitial pneumonia Cause: Porcine circovirus Tissue from a dog. Morphologic Diagnosis: Bilateral everted laryngeal saccules Name an additional lesion in this animal: Tracheal ring hypoplasia 22. Tissue from a rabbit. Morphologic Diagnosis: Multifocal chronic lymphocytic nephritis Cause: Encephalitozoon cuniculi Name an additional lesion in this animal: Lymphocytic encephalitis; cataract 23. Tissue from a horse. Morphologic diagnosis: Multifocal to coalescing granulomatous nephritis Cause: Halicephalobus gingivalis 24. Tissue from an angelfish. Morphologic Diagnosis: Focally extensive thyroid hyperplasia (goiter) 25. Tissue from a horse. Morphologic Diagnosis: Ovarian granulosa cell tumor 26. Tissue from a goat. Morphologic Diagnosis: Multifocal to coalescing proliferative enteritis (mucosal hypertrophy and hyperplasia OK) Cause: Eimeria ninakohlayakimovae (arloingi, christianseni, ovinoidalis) 27. Tissue from a cow. Morphologic diagnosis: Focally extensive fibrinosuppurative valvuitis and mural endocarditis (vegetative valvular endocarditis OK) Name three possible causes: Truperella pyogenes; Bartonella bovis; Staph aureus; Streptococcus bovis,truperella pyogenes; Bartonella bovis; Staph aureus; Streptococcus bovis, E.coli

5 28. Tissue from a pig. Morphologic Diagnosis: Multifocal psoraisiform and pustular eosinophilic dermatitis (proliferative and necrotizing dermatitis OK) Name the condition: Porcine juvenile pustular and psoriasiform dermatitis or pityriasis rosea (swine pox OK if proliferative and necrotizing dermatitis was chosen) 29. Tissue from a sheep. Morphologic Diagnosis: Multifocal to coalescing grey matter laminar necrosis (polioencephalomalacia OK, but not quite as descriptive) Cause: Thiamine deficiency, lead toxicosis, sulfur toxicosis Name the significance of the special test in the lower left: Breakdown of fat in necrotic cerebral tissue releases lipochrome pigments which fluoresce under ultraviolet light 30. Tissue from a pigeon. Morphologic Diagnosis: Multiple proventricular mucosal granulomas Cause: Tetrameres Americana 31. Tissue from a chicken. Morphologic Diagnosis: Hepatic lymphoma (multiple hepatic granulomas OK) Cause: Avian retrovirus (M. avium OK if granulomas chosen) 32. Tissue from a lamb. Morphologic Diagnosis: Focally extensive proliferative and ulcerative gingivitis Cause: Ovine parapoxvirus (contagious ecthyma virus) 33. Tissue from a great blue heron. Cause: Eustrongylides ignotus 34. Tissue from a sheep. Morphologic Diagnosis: Nasal adenocarcinoma Cause: Ovine endogenous beta-retrovirus 35. Tissue from a cat. Pathogenesis: Prolonged anorexia=>diminished blood glucose=>diminished insulin releasel=>lipolysis as well as concurrent lack of dietary protein=> diminished production of apolipoproteins => inability to excrete accumulated triglycerides from the liver => hepatic lipidosis 36. Tissue from a horse. Morphologic Diagnosis: focally extensive cervical subcutaneous and muscular necrosis Cause: Clostridium septicum, chauvoei, sordelli, etc. (almost any will do) Name the condition: Malignant edema

6 37. Tissue from an ox. Morphologic Diagnosis: diffuse fibrinonecrotic tracheitis Cause: Bovine herpesvirus-1 (IBR virus 1 point only) 38. Tissue from a chicken. Morphologic Diagnosis: Multifocal to coalescing granulomatous and necrotizing osteomyelitis Cause: Streptococcus hirae, Staphyloccocus aureus 39. Tissue from a goldfish. Morphologic Diagnosis: Bilateral polycystic kidneys 40. Tissue from a calf. Morphologic Diagnosis: Diffuse cutaneous hypotrichosis (note this is NOT alopecia) Name a second lesion in this individual: Oligodontia 41. Tissue from a cat. Morphologic Diagnosis: Diffuse dental porphria Cause: Congenital lack of uroporphyrinogen-3 cosynthetase Name an associated clinicopathologic abnormality: Hemolytic anemia 42. Tissue from an ox. Morphologic Diagnosis: Multifocal proliferative abomasitis (or abomasal mucosal epithelial hyperplasia and hypertrophy) Cause: Ostertagia ostertagi (or Trichostrongylus circumcincta) Name an associated clinicopathologic abnormality: Hyperpepsinogenemia, hypergastrinemia, or hypoproteinemia 43. Tissue from a dog Morphologic Diagnosis: Diffuse pancreatic hypoplasia Name a diagnostic biochemical test: Serum trypsin-like immunoreactivity 44. Tissue from a calf. Morphologic Diagnosis: Leukotrichia Cause: Copper deficiency 45. Tissue from a raccoon. Name the agent: Dracunculus insignis 46. Tissue from a carp. Cause: Flavobacterium columnaris 47. Tissue from a rhesus macaque Morphologic Diagnosis: Focally extensive pyloric congestion and hemorrhage

7 Cause: Simian filovirus (Ebola, Marburg, Simian Hemorrhagic fever viruses) 48. Tissue from a pig. Morphologic Diagnosis: Diffuse massive hepatic necrosis Cause: Vitamin E/Se imbalance Name the condition: Hepatosis dietetica 49. Tissue from a fairy bluebird. Morphologic Diagnosis: Articular (phalangeal) gout 50. Tissue from a dog. Morphologic Diagnosis: Diffuse intestinal lymphangiectasia Name a likely breed: Yorkshire terrier, Norwegian Lundehund, soft coated wheaten terrier