2014 Descriptive Vet Path Course. Gross Exam #2 KEY

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1 2014 Descriptive Vet Path Course Gross Exam #2 KEY

2 2014 DESCRIPTIVE VETERINARY PATHOLOGY COURSE GROSS EXAM #2 1. Tissue from a chicken. Morphologic Diagnosis: Multifocal proliferative and ulcerative facial dermatitis Cause: Avian poxvirus 2. Tissue from an ox. Morphologic Diagnosis: Focally extensive granulomatous mandibular osteomyelitis Cause: Actinomyces bovis 3. Tissue from a white-tailed deer. Morphologic Diagnosis: Multifocal to coalescing pulmonary edema Cause: Cervid orbivirus (Epizootic hemorrhagic disease virus; cervid adenovirus OK) 4. Tissue from a rabbit. Morphologic Diagnosis: Endometrial venous aneurysms 5. Tissue from a pig. Morphologic Diagnosis: Multifocal to coalescing dermal vasculitis with epidermal necrosis Cause: Eryseipelothrix rhusiopathae 6. Tissue from a dog. Morphologic Diagnosis: Focally extensive mural and valvular fibrinosuppurative endocarditis Name three possible causes: S. aureus, S. canis, any coliform, Bartonella vinsoni, Bartonella Quintana, E. rhusiopathae 7. Tissue from a horse. Morphologic Diagnosis: Multifocal to coalescing granulomatous colitis Cause: Cyathostomes (small strongyles) 8. Tissue from a ferret. Pathogenesis: Early neutering =>elevated levels of LH=>hyperestrogenism=>squamous metaplasia of prostatic glandular epithelium=>suppurative prostatitis 9. Tissue from a squirrel. Morphologic Diagnosis: Multifocal to coalescing ulcerative and proliferative dermatitis Cause: Leporipoxvirus

3 10. Tissue from a dog. Pathogenesis: Renal insufficiency=>elevated levels of circulating BUN=>breakdown by oral bacteria produces ammonia=>caustic burns=>ulcerative glossitis 11. Tissue from a pig. Morphologic Diagnosis: Diffuse fibrinous peritonitis Name three possible causes: Streptococcus suis, Hemophilus parasuis, Mycoplasma hyorhinis 12. Tissue from a canary. Morphologic Diagnosis: Diffuse proliferative and hyperkeratosis pododermatitis Cause: Cnemidocoptes pilae 13. Tissue from a cat. Morphologic Diagnosis: Multiple cranial osteochondromas Cause: Feline retrovirus 14. Tissue from an ox. Morphologic Diagnosis: Esophageal squamous cell carcinoma 15. Tissue from a horse. Morphologic Diagnosis: Cervical vertebral subluxation with hypertrophy of the ligamentum flavum Name the condition: Cervical static stenosis ( Wobbler half credit) 16. Tissue from a chicken. Name the condition: Fatty liver hemorrhagic syndrome 17. Tissue from a guinea pig. Cause Trixacarus caviae 18. Tissue from an ox: Morphologic Diagnosis: Diffuse necrosuppurative placentitis Give two possible causes: Brucella abortus, Aspergillus fumigatus (or other fungus) 19. Tissue from a nude mouse. Morphologic Diagnosis: Multifocal to coalescing hyperkeratotic dermatitis Cause: Corynebacterium bovis 20. Tissue from a cynomolgus monkey. Morphologic Diagnosis: Multifocal to coalescing necrotizing enteritis Cause: Yersinia enterocolitica (pseudotuberculosis OK) Name another affected organ. Spleen, liver

4 21. Tissue from a dog. Morphologic Diagnosis: Pulmonary thrombus Name three possible causes: Elevated corticosteroids (endogenous or exogenous), pancreatitis, glomerulonephritis, amyloidosis, neoplasia 22. Tissue from a cat. Morphologic Diagnosis: Diffuse fibrinous and exudative peritonitis Cause: Mutated feline coronavirus 23. Tissue from a dog. Morphologic diagnosis: Multiple silica uroliths with proliferative and hemorrhagic cystitis Cause: Elevated levels of plants (phytates) in diet 24. Tissue from a dog. Morphologic Diagnosis: Cranial multilobular tumor of bone (chondroma rodens) 25. Tissue from a horse. Morphologic Diagnosis: Ventricular cholesteatoma 26. Tissue from a pig. Morphologic Diagnosis: Bilateral tonsillar necrosis Give two possible causes: Porcine herpesvirus-1 (pseudorabies virus), porcine pestivirus, Fusibacterium necrophorum 27. Tissue from a snake. Name the agent: Armillifer armillatus, Porocephalus crotali 28. Tissue from a calf. Morphologic Diagnosis: Focal ulcerative keratitis Cause: Moraxella bovis 29. Tissue from an ox. Morphologic Diagnosis: Myocardial lymphangiectasia 30. Tissue from a Tasmanian devil. Name the condition: Devil facial tumor disease Name the cell of origin: Schwann cell 31. Tissue from a snake. Morphologic Diagnosis: Multifocal suppurative vertebral osteomyelitis Cause: Salmonella arizonae 32. Tissue from a tiger. Pathogenesis: Chronic administration of NSAIDS =>decreased production of

5 PgE2 and PgI2=>closure of medullary vasa recta=>local hypoxia=>renal papillary necrosis 33. Tissue from a chicken. Name the condition: Visceral gout 34. Tissue from a dog. Give four differential diagnoses: Thyroid carcinoma, chemodectoma (aortic and carotid body), lymphoma, hemangiosarcoma, parathyroid carcinoma 35. Tissue from a pig. Morphologic Diagnosis: Diffuse fibrinonecrotic colitis Cause: Brachyspira hyodysenteriae 36. Tissue from a cat. Morphologic Diagnosis: Diffuse parathyroid hyperplasia Cause: Elevated phosphorus levels due to chronic renal disease 37. Tissue from a donkey. Morphologic Diagnosis: Diffuse pulmonary fibrosis Cause: Asinine herpesvirus Tissue from a guinea pig. Morphologic Diagnosis: Diffuse necrotizing typhlitis Cause: Clostridium difficile (spiroforme) Name an predisposing event: Administration of penicillin 39. Tissue from a pig. Morphologic Diagnosis: Multifocal to coalescing eosinophilic hepatitis with fibrosis (milk spots) Cause: Ascaris suus migration 40. Tissue from a dog. Morphologic Diagnosis: Preputial transmissible venereal tumor 41. Tissue from a piglet. Morphologic Diagnosis: Multifocal to coalescing renal tubular sulfate crystals Cause: Dehydration and concurrent administration of sulfonamides 42. Tissue from a dog. Name the condition: Necrotizing encephalopathy of sled dogs

6 43. Tissue from a turkey. Give two morphologic diagnoses: Multifocal to coalescing hepatic necrosis and diffuse fibrinonecrotic typhlitis Cause: Histomonas meleagridis 44. Tissue from an ox. Morphologic Diagnosis: Ectopia cordis 45. Tissue from a goat. Morphologic Diagnosis: Diffuse lymphocytic and proliferative interstitial pneumonia Cause: Caprine lentivirus Name two other lesions in this animal: Chronic lymphocytic mastitis, lymphocytic meningoencephalitis with multifocal necrosis 46. Tissue from a snake. Morphologic Diagnosis: Multifocal to coalescing fibrinonecrotis stomatitis Cause: Aeromonas hydrophila or Pseudomonas aeruginosa Name the condition: Necrotic stomatitis 47. Tissue from a pig. Morphologic Diagnosis: Multifocal to coalescing renal vasculitis with necrotis Cause: Porcine circovirus Tissue from a pig. Morphologic Diagnosis: Diffuse proliferative ileitis Cause: Lawsonia intracellularis 49. Tissue from a guinea pig. Morphologic Diagnosis: Diffuse severe fibrinous pleuropneumonia Cause: Steptococcus pneumoniae 50. Tissue from a shark. Morphologic Diagnosis: Multifocal to coalescing dermal vasculitis with epidermal necrosis Cause: Fusarium solani

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