OIE Reference Laboratory Reports Activities
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1 OIE Reference Laboratory Reports Activities Activities in 2013 This report has been submitted : :42:16 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot and mouth disease Address of laboratory: Yur'evets Vladimir RUSSIA Tel.: Fax: address: mail@arriah.ru website: Name (including Title) of Head of Laboratory (Responsible Official): Mischenko A.V., Head of Reference Laboratory for FMD diagnosis, Candidate of Science (Veterinary Medicine) Scherbakov A.V., Head of Reference Laboratory for Highly Dangerous Diseases, Candidate of Science (Biology) Name (including Title and Position) of OIE Reference Expert: Valery Zakharov Which of the following defines your laboratory? Check all that apply: Governmental OIE Reference Laboratory Reports Activities,
2 ToR: To use, promote and disseminate diagnostic methods validated according to OIE Standards 1. Did your laboratory perform diagnostic tests for the specified disease/topic for purposes such as disease diagnosis, screening of animals for export, surveillance, etc.? (t for quality control, proficiency testing or staff training) Diagnostic Test Indicated in OIE Manual (/) Total number of test performed last year Indirect diagnostic tests Nationally Internationally Liquid phase blocking indirect ELISA (LPB ELISA) 56,918 2,109 Virus neutralization test Indirect ELISA (ELISA-NSP) 28, Vaccine matching in VNT 67 8 Direct diagnostic tests Nationally Internationally Virus isolation in cell culture Indirect double sandwich ELISA CFT RT-PCR, VP1 gene VP1 gene sequencing ToR: To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards. To store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens or disease. 2. Did your laboratory produce or supply imported standard reference reagents officially recognised by the OIE? 3. Did your laboratory supply standard reference reagents (non OIE-approved) and/or other diagnostic reagents 2 OIE Reference Laboratory Reports Activities, 2013
3 to OIE Member Countries? 4. Did your laboratory produce vaccines? 5. Did your laboratory supply vaccines to OIE Member Countries? Vaccine name Amount supplied nationally (ml, mg) (including for own use) Amount supplied to other countries (ml, mg) Name of recipient OIE Member Countries Sorbat, mono- and polyvalent FMD vaccine (based on the virus grown in BHK-21 cells) 20, thousand doses 2, thousand doses SAUDI ARABIA Sorbat, mono- and polyvalent FMD vaccine (based on the virus grown in BHK-21 cells) 2, thousand doses GEORGIA Sorbat, mono- and polyvalent FMD vaccine (based on the virus grown in BHK-21 cells) 9, thousand doses KAZAKHSTAN Sorbat, mono- and polyvalent FMD vaccine (based on the virus grown in BHK-21 cells) 5,885 thousand doses AZERBAIJAN Emulsion, mono- and polyvalent FMD vaccine (based on the virus grown in BHK-21 cells) thousand doses CHINESE TAIPEI ToR: To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases 6. Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease? 7. Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease? OIE Reference Laboratory Reports Activities,
4 Name of the new test or diagnostic method or vaccine developed Description and References (Publication, website, etc.) Recommended practice for FMD virus typing by PCR Scherbakov A.V., Timina A.M., Perevozchikova N.A. Diagnosis of FMD of all serotypes by real-time PCR // Veterinarnaya Praktika (58).-P Cultural inactivated emulsion FMD vaccine ARRIAH-VAC D.V. Mikhalishin Dependence of immunity duration in cattle vaccinated with FMD emulsion vaccine on its activity // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P ToR: To provide diagnostic testing facilities, and, where appropriate, scientific and technical advice on disease control measures to OIE Member Countries 8. Did your laboratory carry out diagnostic testing for other OIE Member Countries? Name of OIE Member Country seeking assistance Date (month). samples received for provision of diagnostic support. samples received for provision of confirmatory diagnoses KAZAKHSTAN KAZAKHSTAN MONGOLIA KAZAKHSTAN Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country? ToR: To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations 10. Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries other than the own? 4 OIE Reference Laboratory Reports Activities, 2013
5 Title of the study Duration Purpose of the study Partners (Institutions) Characterization of FMDV strains under the Agreement with the US Department of Agriculture ( F) 1.5 years ( ) Revival of FMDV strains in cell culture and cattle, identification of nucleotide sequences of genes of FMDV NSP VP1-VP US Department of Agriculture Development of Real time PCR for differential diagnosis of FMD and swine vesicular disease under the EurAsEC International Target Program Innovative Biotechnologies 3 years ( ) Improvement of methods of differential diagnosis of FMD and SVD RUE S.N. Vyshelessky Institute of Experimental Veterinary Medicine Agreement between FAO and FGBI ARRIAH 2013 Services related to the development and validation of non-invasive sampling techniques in wild boar for the detection of FMDV genome FAO EUFMD ToR: To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases 11. Did your Laboratory collect epizootiological data relevant to international disease control? 12. Did your laboratory disseminate epizootiological data that had been processed and analysed? 13. What method of dissemination of information is most often used by your laboratory? (Indicate in the appropriate box the number by category) a) Articles published in peer-reviewed journals: Multiple introductions of serotype O foot-and-mouth disease viruses into East Asia in Valdazo- González B., Timina A., Scherbakov A., Abdul-Hamid N.F., Knowles N.J., King D.P. // Vet Res. 2013, V. 44(1), P А.М. Rakhmanov, V.L. Uzyumov History of establishment and activities of the All-Union Scientific and Research FMD Institute // Veterinary medicine today, (4).-P A.V. Mishenko, V.O. Chernykh, Comparative assessment of methods of blood collection in pigs // Veterinary medicine in the Kuban, P A.V. Mishenko Reasons for FMD spread in Russia and restrictions on grain supplies to Ukraine due to the disease outbreak in the South of the country // Agrobezopasnost, P V.М. Gulenkin, F.I. Korennoy Mathematic modeling of risks of highly dangerous disease spread from focuses of infection // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P V.I. Diyev, S.А. Ashurov, А.V. Konstantinov, D.K. Basova Dependence of FMD A22 clinical signs in sheep on the level of virus adaptation and different techniques of infection // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P S.R. Kremenchugskaya FMDV strain differentiation // Veterinary medicine and feeding, :[materials of OIE Reference Laboratory Reports Activities,
6 the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-С D.V. Mikhalishin Cultural FMDV inactivation for FMD vaccine production // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P D.V. Mikhalishin Dependence of immunity duration in cattle vaccinated with FMD emulsion vaccine on its activity // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P D.V. Mikhalishin, T.N. Lezova, A.V. Borisov, A.V. Konstantinov Improvement of FMD vaccine control method // [Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P D.V. Mikhalishin, M.N. Guseva, V.V. Mikhalishin, V.D. Yurchishin Studies of influence of osmotic pressure on FMDV reproduction // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P A.V. Mishenko Retrospective analysis of FMD epizootic situation in Transbaikal // Veterinary medicine and feeding, :[materials of the International Research and Training Conference «Achievements and development trends of veterinary science», devoted to the 55th Anniversary of FGBI ARRIAH ].-P A.V. Mishenko, V.A. Mishenko, G.A. Dzhailidi [et al] FMD vaccine field efficacy // Veterinary Medicine in the Kuban, P A.V. Mishenko, Tsolmon Bandi, D.V. Mikhalishin, V.A Mishenko, V.M. Zakharov Efficacy of the system of FMD epizootic measures in Mongolia // Veterinary medicine P D.V. Mikhalishin, A.V. Mishenko, V.M. Zakharov FMD buffer zone efficacy in Transcaucasia // Veterinary medicine P b) International conferences: 5 1. А.М. Rakhmanov Preventive vaccination of animals against FMD in Privolzhsky Federal District // Biotechnology: reality and prospects in agriculture: materials of the International Research and Training Conference: Devoted to the 100th Anniversary of Saratov State Agrarian University named after N.I. Vavilov - Saratov, P V.A. Mishenko, A.M. Rakhmanov Provision of livestock freedom from infectious diseases under the current conditions // Major fields of veterinary service improvement in the epoch of potency and happiness: materials of the International Scientific Conference. -Asgabad, P D.V. Mikhalishin Efficacy of FMD vaccines under the current conditions // Major fields of veterinary service improvement in the epoch of potency and happiness: materials of the International Scientific Conference. - Asgabad, P А.М. Rakhmanov, S.R. Kremenchugskaya, А.V. Mishenko Preventive vaccination of animals against FMD in Siberian Federal District P. 2// Topical issues of veterinary medicine in Siberia: materials of the International Research and Training Conference. - Ulan Ude, P А.М. Rakhmanov FMD epizootic situation in the world and control measures under current conditions // VIEF works. V. 77. Current state and development trends of the veterinary science in Russia: materials of the International Research and Training Conference. -М., P c) National conferences: 0 d) Other: (Provide website address or link to appropriate information) 8 1. А.М. Rakhmanov Current FMD epizootic situation in the world and FMD control measures // Veterinary Medicine: мiжвiд. тем. наук. зб.. - Kharkiv, P S.R. Kremenchugskaya, T.K. Mayorova, N.N. Lugovskaya Participation of FGBI ARRIAH as OIE FMD Regional Reference Laboratory in FAO/OIE proficiency testing for FMD and swine vesicular disease diagnostics // Works of the Federal Centre for Animal Health. Izhevsk, v. 11.-P А.М. Rakhmanov, S.R. Kremenchugskaya, N.E. Kamalova, A.V. Sherbakov Immune status assessment of cattle of different age after vaccination in FMD buffer zone // Works of the Federal Centre for Animal Health. Izhevsk, v. 11.-P FMD prognosis for livestock in the Russian Federation in 2013/V.M. Gulyenkin, А.V. Sherbakov, А.V.Mishenko, S.А. Dudnikov // Prognoses for several animal diseases in the Russia Federation in 2013 / FGBI ARRIAH. - Vladimir, Prognoses for several animal diseases in the Russian Federation in 2013 (African swine fever, FMD, highly pathogenic avian influenza, classical swine fever, bluetongue, rabies, Newcastle disease, sheep/goat pox, peste 6 OIE Reference Laboratory Reports Activities, 2013
7 des petit ruminants, bovine spongiform encephalopathy )/FGBI ARRIAH Emergent diseases // Veterinary life, Veterinary medicine news: Poultry. African swine fever. FMD // Veterinary life, (April).-P.1 8. Special meeting of the Intergovernmental Council between the CIS countries on cooperation in the veterinary field regarding FMD prevention // Veterinary life, P.6 ToR: To provide scientific and technical training for personnel from OIE Member Countries To recommend the prescribed and alternative tests or vaccines as OIE Standards 14. Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries? a) Technical visits: 4 b) Seminars: 10 c) Hands-on training courses: 10 d) Internships (>1 month): 0 Type of technical training provided (a, b, c or d) Country of origin of the expert(s) provided with training. participants from the corresponding country a Russian Federation 2 a Republic of Kazakhstan 2 c Russian Federation 8 c Poland 2 ToR: To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned 15. Does your laboratory have a Quality Management System certified according to an International Standard? Quality management system adopted GOST R ISO (ISO 9001:2011) 16. Is your laboratory accredited by an international accreditation body? 17. Does your laboratory maintain a biorisk management system for the pathogen and the disease concerned? OIE Reference Laboratory Reports Activities,
8 (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals 2012, Chapter or Manual of Diagnostic Tests for Aquatic Animals 2012, Chapter 1.1.1) ToR: To organise and participate in scientific meetings on behalf of the OIE 18. Did your laboratory organise scientific meetings on behalf of the OIE? National/ International Title of event Co-organiser Date (mm/yy) Location. Participants International Third Meeting of the Project on Cross Border Trade and TADs Risk Reduction (with a special focus on FMD) between China and Mongolia (TCP/RAS/3306 B04) FAO January 22-25, 2013 FGBI "ARRIAH" Vladimir, Russia 40 International 36th Meeting of the Intergovernmental Council for Cooperation in the Veterinary Field in CIS countries Department of veterinary medicine of the RF Ministry of Agriculture April 5, 2013 FGBI "ARRIAH" Vladimir, Russia 25 International Workshop on the prevention and eradication of foot and mouth disease in the Central Asian region EU FMD June 25-26, 2013 FGBI "ARRIAH" Vladimir, Russia Did your laboratory participate in scientific meetings on behalf of the OIE? 8 OIE Reference Laboratory Reports Activities, 2013
9 Title of event Date (mm/yy) Location Role (speaker, presenting poster, short communications) Title of the work presented West EurAsia FMD Control - Roadmap th Regional Progress Review Meeting 2-4 April 2013 Baku, Azerbaijan Short presentation FMD control in Russia International Conference «Major fields of veterinary service improvement» September 6-7, 2013 Avaz city (Turkmenistan) Short presentation Provision of livestock freedom from infectious diseases under the current conditions the 2nd Meeting of the Coordination Committee and scientific meeting for the Central Asia» (according to the OIE/JIF project for FMD control in Asia) October 5 8, 2013 Republic of Mongolia Short presentation FMD Epidemic Situation in Russian Federation in Network Annual meeting vember 2013 Bangkok (Thailand) Short report Report on the activities of the OIE Reference Laboratory for FMD (FGBI ARRIAH ) for the period from January to vember 2013 ToR: To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results 20. Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease? 21. Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests? Purpose of the proficiency tests: 1 Role of your Reference Laboratory (organiser/ participant). participants Participating OIE Ref. Labs/ organising OIE Ref. Lab. Proficiency test in FMD and SVD diagnosis Participant European Community of reference Laboratory for FMD and SVD and FAO/OIE World Reference Laboratory for FMD (Pirbright, United Kingdom) (Organizers) OIE Reference Laboratory Reports Activities,
10 1 validation of a diagnostic protocol: specify the test; quality control of vaccines: specify the vaccine type, etc. 22. Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest? ToR: To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results 23. Did your laboratory organise or participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease? te: See Interlaboratory test comparisons in: Laboratory Proficiency Testing at: see point 1.3 Purpose for inter-laboratory test comparisons 1. participating laboratories Region(s) of participating OIE Member Countries Harmonization of methods of FMD diagnosis 7 Africa Americas Asia and Pacific Europe Middle East ToR: To place expert consultants at the disposal of the OIE 24. Did your laboratory place expert consultants at the disposal of the OIE? 25. Additional comments regarding your report: 10 OIE Reference Laboratory Reports Activities, 2013
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