OIE Reference Laboratory Reports Activities

Transcription

1 OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : :19:13 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot and mouth disease Address of laboratory: Yur'evets Vladimir RUSSIA Tel.: Fax: address: mail@arriah.ru Website: Name (including Title) of Head of Laboratory (Responsible Official): S.N. Fomina Head of Reference Laboratory for FMD diagnosis. Candidate of Science (Veterinary Medicine) A.V. Scherbakov Head of Reference Laboratory for Highly Dangerous Diseases. Candidate of Science (Biology) Name (including Title and Position) of OIE Reference Expert: V.M.Zakharov doctor of Science (Veterinary Medicine), professor Which of the following defines your laboratory? Check all that apply: Governmental OIE Reference Laboratory Reports Activities,

2 ToR 1: To use, promote and disseminate diagnostic methods validated according to OIE Standards 1. Did your laboratory perform diagnostic tests for the specified disease/topic for purposes such as disease diagnosis, screening of animals for export, surveillance, etc.? (Not for quality control, proficiency testing or staff training) Diagnostic Test Indicated in OIE Manual (/No) Total number of test performed last year Indirect diagnostic tests Nationally Internationally Liquid phase blocking indirect ELISA (LPB ELISA) yes 135, Virus neutralization test yes Indirect ELISA (ELISA-NSP) yes 25,721 no Vaccine matching in VNT yes Direct diagnostic tests Nationally Internationally Virus isolation in cell culture yes Indirect double sandwich ELISA yes CFT yes Real-time RT-PCR, 3D gene yes Real-time RT-PCR, 5 HTO gene yes RT-PCR, VP1 gene yes 20 (16-Asia1, 4-O) 14 (5-O, 9-A) VP1 gene sequencing yes 8 14 ToR 2: To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards. To store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens 2 OIE Reference Laboratory Reports Activities, 2016

3 or disease. 2. Did your laboratory produce or supply imported standard reference reagents officially recognised by the OIE? No 3. Did your laboratory supply standard reference reagents (non OIE-approved) and/or other diagnostic reagents to OIE Member Countries? OIE Reference Laboratory Reports Activities,

4 Type of reagent available Related diagnostic test Produced/ provide Amount supplied nationally (ml, mg) Amount supplied internationally (ml, mg) No. of recipient OIE Member Countries Region of recipients Kit for of FMD antibodies in animal sera by ELISA LPB ELISA ,797 kits 4 America s Asia and Pacific Middle East Kit for of FMD antibodies in animal sera by ELISA LPB ELISA kits 1 America s Asia and Pacific Middle East Kit for of FMD antibodies in animal sera by ELISA LPB ELISA kits 9 kits 3 America s Asia and Pacific Middle East Kit for FMDV antigen by ELISA Ag ELISA... 8 kits 3 America s Asia and Pacific Middle East Kit for FMDV antigen by ELISA Ag ELISA kits 3 kits 3 America s Asia and Pacific Middle East 4. Did your laboratory produce vaccines? 4 OIE Reference Laboratory Reports Activities, 2016

5 5. Did your laboratory supply vaccines to OIE Member Countries? Vaccine name Amount supplied nationally (ml, mg) (including for own use) Amount supplied to other countries (ml, mg) Name of recipient OIE Member Countries Sorbat, mono-and polivalent FMD vaccine (based on the virus grown in BHK-21 cells)... 18,954.2 thousand doses KAZAKHSTAN Emulsion, mono- and polivalent FMD vaccine (based on the virus grown in BHK-21 cells)arriah-vac 2,475 thousand doses 7,585 thousand doses IRAQ Sorbat, mono-and polivalent FMD vaccine (based on the virus grown in BHK-21 cells) 3, thousand doses 2,759 thousand doses KYRGYZSTAN Emulsion, mono- and polivalent FMD vaccine (based on the virus grown in BHK-21 cells)arriah-vac 300 thousand doses 8,160 thousand doses KOREA (REP. OF) Emulsion, mono- and polivalent FMD vaccine (based on the virus grown in BHK-21 cells) 245 thousand doses 4,910.6 thousand doses CHINESE TAIPEI ToR 3: To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases 6. Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease? No 7. Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease? Name of the new test or diagnostic method or vaccine developed Description and References (Publication, website, etc.) Vaccine against type A genetic line A G VII FMDV Development of new vaccine against type A genetic line А GVII FMD virus and its supply to the Republic of Armenia // Veterinariya segodnya, V.No. 2.-p.6 OIE Reference Laboratory Reports Activities,

6 ToR 4: To provide diagnostic testing facilities, and, where appropriate, scientific and technical advice on disease control measures to OIE Member Countries 8. Did your laboratory carry out diagnostic testing for other OIE Member Countries? Name of OIE Member Country seeking assistance Date (month) No. samples received for provision of diagnostic support No. samples received for provision of confirmatory diagnoses ARMENIA January 0 4 KAZAKHSTAN May 16 MONGOLIA August 5 RUSSIA January-November Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country? No ToR 5: To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations 10. Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries other than the own? 6 OIE Reference Laboratory Reports Activities, 2016

7 Title of the study Duration Purpose of the study Partners (Institutions) OIE Member Countries involved other than your country Cross Border Trade and TADs Risk Reduction between China, Mongolia and Russia 2 years Improvement of Mongolian cattle from highly dangerous animal diseases, including foot and mouth disease State Central Veterinary Laboratory,Ulaanbaatar MONGOLIA the Complex of CIS Joint Measures for FMD Prevention and Control until 2020 Adopted at 40th Meeting of Intergovernmental Council for Cooperation in Veterinary Medicine on April 5, 2013 in Vladimir, Russia APPROVED By the Council of the CIS Government Executives On May 30, 2014 in Minsk until 2020 AZERBAIJAN ToR 6: To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases 11. Did your Laboratory collect epizootiological data relevant to international disease control? 12. Did your laboratory disseminate epizootiological data that had been processed and analysed? 13. What method of dissemination of information is most often used by your laboratory? (Indicate in the appropriate box the number by category) a) Articles published in peer-reviewed journals: 10 1 D. А. Lozovoy, D.V. Mikhalishin, T.N. Lyozova [et al.] Sorbate vaccine effectiveness against heterologous strains of type A foot-and-mouth disease virus // Veterinariya, V. No.2.-pp D.A. Lozovoy, А.М. Rakhmanov FMD epidemic situation in the world in and control measures // Veterinariya segodnya, V.No. 1.-pp A. V. Mischenko, V. А. Mischenko, V. N. Shevkoplyas [et al.] Problem of biosafety of herds of cattle of beef breeds // Veterinariya Kubani, V.No. 1.-pp.4-7;URL: 4. Development of new vaccine against type A genetic line А GVII FMD virus and its supply to the Republic of Armenia // Veterinariya segodnya, V.No. 2.-p.6 5. D.А. Lozovoy Implementation of joint complex measures by the CIS-countries aimed at FMD prevention and control in animals // International Agricultural Journal, V.No. 4.-pp OIE recognition of official FMD status of the Russian Federation // Veterinariya segodnya, V.No. 3.-p.6 7. N.N. Lugovskaya, S. R. Kremenchugskaya Analysis of the results of proficiency tests carried out by the OIE Reference Laboratory Reports Activities,

8 Reference Laboratory for FMD Diagnosis of the FGBI ARRIAH in // Veterinariya segodnya, V.No. 3.-pp D.А. Lozovoy, V.А. Starikov, D.V. Mikhalishin, А.V. Borisov Dependence of emulsion FMD vaccine immunogenicity on immune status of pigs // Veterinariya segodnya, V.No.3.-pp D.А. Lozovoy Foot-and-mouth disease in animals, its diagnosis and prevention // Agrarnik, V.No. 7.- pp M.N.Guseva, D.V. Mikhalishin, A.A. Shishkova [et al] Optimization of nutrient medium composition for BHK-21/2-17 suspension culture // Veterinariya segodnya, V.No. 4.-pp b) International conferences: 3 1. А.V. Mischenko FMD epidemic situation in the West Eurasian countries in 2015 / 7th Regional FMD West Eurasia Roadmap Meeting, Bishkek, Kyrgyzstan, S.K. Abdrakhmanov, S.B. Tyulegenov, I.I. Sytnik, F.I. Korennoy, K.K. Beisembayev Spatio-temporal analysis of foot-and-mouth disease epidemic situation among farm animals in the Republic of Kazakhstan for the period of // Europ Commiss. Control FMD. Open Sess. Standing Techn. and Research Comm. Europ. Commiss. Control FMD. OS`16. The Practice of Innovation. -Rome, С V.P.Semakina, V.A. Mischenko FMD threat to Russian Livestock // Achievements of young scientists - in veterinary practice: Proceedings of the 4th Int. scientific. conf., is dedicated. 55th anniversary of postgraduate FGBU "ARRIAH". - Vladimir, P c) National conferences: 0 d) Other: (Provide website address or link to appropriate information) 2 1.А. К. Karaulov, А. V. Scherbakov, V. M. Gulyonkin [et al.] Forecast for foot-and-mouth disease in livestock in the Russian Federation for 2016 // Forecasts for several animal diseases in the Russian Federation for 2016/ FGBI ARRIAH. -Vladimir, pp ToR 7: To provide scientific and technical training for personnel from OIE Member Countries To recommend the prescribed and alternative tests or vaccines as OIE Standards 14. Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries? a) Technical visits: 7 b) Seminars: 2 c) Hands-on training courses: 0 d) Internships (>1 month): 0 8 OIE Reference Laboratory Reports Activities, 2016

9 Type of technical training provided (a, b, c or d) Country of origin of the expert(s) provided with training No. participants from the corresponding country а Iran 5 a Iraq 6 a Iraq 8 a Vietnam 5 a Republic of Korea 6 a Republic of Korea 5 a Tailand 3 b Khabarovsk, Russia, June 8-9, b FGBI ARRIAH, Vladimir, November 1, ToR 8: To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned 15. Does your laboratory have a Quality Management System certified according to an International Standard? Quality management system adopted Certificate scan (PDF, JPG, PNG format) ISO , RA.RU.21АО46 number of accreditation certificate аттестат_лдц.pdf 16. Is your laboratory accredited by an international accreditation body? No 17. Does your laboratory maintain a biorisk management system for the pathogen and the disease concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, Chapter 1.1.4) OIE Reference Laboratory Reports Activities,

10 ToR 9: To organise and participate in scientific meetings on behalf of the OIE 18. Did your laboratory organise scientific meetings on behalf of the OIE? National/ International Title of event Co-organiser Date (mm/yy) Location No. Participants International The 6th meeting on the project Cross Border Trade and TADs Risk Reduction between China, Mongolia and Russia was held under the FAO umbrella in the Rosselkhoznadzor subordinate FGBI ARRIAH FAO October, 2016 ARRIAH, Vladimir, Russia 40 International IV International Scientific Conference "Achievements of young scientists in the veterinary practice" dedicated to the 55th anniversary of the establishment of postgraduate training to researchers in FGBI "ARRIAH". 6 December, 2016 ARRIAH, Vladimir, Russia Did your laboratory participate in scientific meetings on behalf of the OIE? 10 OIE Reference Laboratory Reports Activities, 2016

11 Title of event Date (mm/yy) Location Role (speaker, presenting poster, short communications) Title of the work presented The 7th West Eurasia meeting form 6th-8th, 2016 for evaluating FMD control programs 6 th - 8 th of April, 2016 Bishkek, Kyrgyzstan speaker FMD epidemic situation in West Eurasia countries in 2015 VI International Veterinary Congress April 2016 Sochi, Russia speaker Foot and mouth disease - actual questions disease control International Workshop on Veterinary epidemiology (HPAI and FMD) August, 2016 Gimcheon, South Korea speaker Prevention and control of FMD in the Far East of Russia International meeting on the eradication of foot and mouth disease and peste des petits ruminants in Pakistan September 2016 Islamabad, Pakistan speakers 1.Production and control of vaccine in FGBI "ARRIAH" 2.Selection the current vaccine strains for the control of FMD in Pakistan Open Session of the EuFMD Standing Technical Committee October 2016 Cascais, Portugal 11th OIE/FAO FMD Reference Laboratory Network Annual Meeting 30 November 2 December, 2016 Paris, France speaker Report of OIE Regional Reference Laboratory for FMD for Eastern, Central Asia and Transcaucasia (ARRIAH) 2016 ToR 10: To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results 20. Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease? 21. Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests? OIE Reference Laboratory Reports Activities,

12 Purpose of the proficiency tests: 1 Role of your Reference Laboratory (organiser/ participant) No. participants Participating OIE Ref. Labs/ organising OIE Ref. Lab. validation of a diagnostic protocol in FMD and SVDV participant 78 an Community of reference Laboratory for FMD and SVD and FAO/OIE World Reference Laboratory for FMD (Pirbright, United Kingdom) (Organizers) 1 validation of a diagnostic protocol: specify the test; quality control of vaccines: specify the vaccine type, etc. 22. Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest? Title of the project or contract Scope Name(s) of relevant OIE Reference Laboratories Molecular epidemiology of FMDV outbreaks Exchange genomic sequences of FMDV,according to Memorandum of understanding for OIE/FAO Network for FMD Reference Laboratories FMD WRL (Pirbright, UK) ToR 11: To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results 23. Did your laboratory organise or participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease? Note: See Interlaboratory test comparisons in: Laboratory Proficiency Testing at: see point OIE Reference Laboratory Reports Activities, 2016

13 Purpose for inter-laboratory test comparisons 1 No. participating laboratories Region(s) of participating OIE Member Countries Harmonization of methods of FMD diagnosis - ELISA for FMD virus antigen (Ag ELISA) - ELISA for FMD antibody (LPB ELISA) 3 Americas Asia and Pacific Middle East Harmonization of methods of FMD diagnosis - ELISA for FMD virus antigen (Ag ELISA) - ELISA for FMD antibody (LPB ELISA) 3 Americas Asia and Pacific Middle East ToR 12: To place expert consultants at the disposal of the OIE 24. Did your laboratory place expert consultants at the disposal of the OIE? No 25. Additional comments regarding your report: OIE Reference Laboratory Reports Activities,