RESEARCH ARTICLE. Supplemental Figure 5
|
|
|
- Gladys Ross
- 5 years ago
- Views:
Transcription
1 RESEARCH ARTICLE RBC ( 1 12 /L) PLT ( 1 9 /L) HGB (g/l) Cellulr & Moleulr Immunology dvne online pulition, PCV (%) 44 MCV (fl) ; doi:1.13/mi Supplementry Informtion 42 ompnies the pper on Supplementl Figure 4 42 Cellulr & Moleulr4Immunology s wesite ( 3 4 Supplementl Figure 5 Supplementl Figure 1 Supplementl Figure Figure 1 Effets 2 of BDE-29 exposure on the hemtologil prmeters in dult mie. BDE-29 exposed mie were intrgstrilly dministered Supplementl BDE-29 Figure with3 different doses of, or mg/kg w t 2-dy intervls. Peripherl lood ws olleted from ontrol nd BDE-29 exposed mie t month 1, nd the hemtologil prmeters inluding red lood ells (RBC), pltelets (PLT), hemogloin (HGB), pked ell volume (PCV) nd men orpusulr volume (MCV) were deteted y HEMAVET 9 multispeies hemtology instrument (DREW Sientifi In.). The dt were nlyzed y one-wy ANOVA (men6s.d.). BDE, rominted diphenyl ether; w, ody weight. Cellulr & Moleulr Immunology: doi:1.13/mi
2 11.5%.5% 77.9% 79.% 1.% 13.5% 1.3% 1.1% CD4 2.9% 3.2% 2.% 2.4% CD % CD4 SP % CD SP % CD4CD DP # of CD4 SP/thymus ( 1 6 ) # of CD SP/thymus ( 1 6 ) # of CD4CD DP/thymus ( 1 6 ) 1 # thymoytes/thymus ( 1 6 ) 2 1 Supplementl Figure 2 BDE-29 exposure did not signifintly ffet the perentges nd numers of T-ell supopultions in the thymus. Thymoytes were olleted from ontrol nd BDE-29 exposed mie with dose of, or mg/kg w t month 3, nd the perentges nd numers of CD4 1 single-positive (CD4 SP), CD 1 single-positive (CD SP) nd CD4 1 CD 1 doule-positive (CD4CD DP) T ells in thymus were lulted y flow ytometry through stining with nti-cd3e, nti-cd4 nd nti-cd. () As shown in the flow digrm (gted on thymoytes), the perentges indite the popultion of CD4 SP, CD SP nd CD4CD DP T ells in thymoytes. The dt were nlyzed y one-wy ANOVA (men6s.d.). BDE, rominted diphenyl ether; w, ody weight. Cellulr & Moleulr Immunology: doi:1.13/mi
3 .2%.2%.1%.1% CD11 Ly6G CD11.1%.1%.1%.1% % Neu in thymoytes # of Neu/thymus ( 1 6 ) CD11 % DCs in thymoytes # of DCs/thymus ( 1 6 ) Supplementl Figure 3 BDE-29 exposure did not ffet the perentges nd numers of CD11 1 Ly6G 1 neutrophils nd CD11 1 CD11 1 dendriti ells in the thymus. Thymoytes were isolted from ontrol nd BDE-29 exposed mie with dose of, or mg/kg w t month 3, nd the perentges nd numers of CD11 1 Ly6G 1 Neu nd CD11 1 CD11 1 DCs were lulted y flow ytometry through stining with nti- CD11, nti-ly6g nd nti-cd11. () As shown in the flow digrm (gted on thymoytes), the perentges (%) indite the popultion of CD11 1 Ly6G 1 neutrophils nd CD11 1 CD11 1 dendriti ells in thymoytes. The dt were nlyzed y one-wy ANOVA (men6s.d.). BDE, rominted diphenyl ether; w, ody weight; DC, dendriti ell; Neu, neutrophils. Cellulr & Moleulr Immunology: doi:1.13/mi
4 IL-2 IFN-g BDE CD % IFN-g of CD + T % IL-2 of CD + T ** * SSC BDE-29 Supplementl Figure 4 Long-term exposure to BDE-29 y dose of mg/kg w hd dverse effets on the funtionlity of spleni CD T ells. Splenoytes were olleted from ontrol nd BDE-29 exposed mie t month 27, nd IFN- nd IL-2 produtions of CD T ells were mesured y intrellulr ytokine stining following PMA ( ng/ml) nd ionomyin ( ng/ml) stimultion for 5 h in vitro. As shown in the flow digrm (gted on CD 1 T ells), the perentges (%) indite IFN-- or IL-2-positive popultion of CD 1 T ells (left pnels). Br grphs disply the orresponding sttistil results of IFN- 1 CD 1 T ells or IL-2 1 CD 1 T ells etween ontrol nd BDE-29 exposed mie. The dt were nlyzed y using unpired Student s t-test (men6s.d., *P,.5, **P,.1). BDE, rominted diphenyl ether; w, ody weight. Cellulr & Moleulr Immunology: doi:1.13/mi
5 T CM 16.3 BDE T EM CD27 CD27 CCR CCR BDE CD44 5. CD122 CD127 Supplementl Figure 5 Effet of BDE-29 exposure on the phenotype of CD T ells. BDE-29 exposed mie were intrgstrilly dministered with BDE-29 y dose of mg/kg w t 2-dy intervls, nd the peripherl lood were olleted from ontrol nd BDE-29 exposed mie t month 5. () The expressions of CD27 nd CCR7 were nlyzed on the entrl memory (T CM,CD44 hi CD62L hi ) or effetor memory (T EM, CD44 hi CD62L lo ) phenotype CD T ells. () The perentges (%) indite the popultions of CD44 hi CD27 hi, CD44 hi CD27 lo, CD44 hi CCR7 hi nd CD4 hi CCR7 lo of CD 1 T ells. () The numers indite the MFI of CD122 nd CD127 on CD 1 T ells. BDE, rominted diphenyl ether; w, ody weight; MFI, medin fluoresent intensity. Cellulr & Moleulr Immunology: doi:1.13/mi
Supplementary Figure S1
Supplementry Figure S1 - UTR m - 3HA - 2-1 hgh - 1 Uiquitin *! *! lk distl promoter m K3R/ K121R-3HA UTR hgh founder lines - HA - - founder lines TG- E1 L A2 B1 F9 G6 H4 H6 B C D2 G1 H3 J2 L - 7 IP: lk
SUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION CD169 + MACROPHAGES PRESENT LIPID ANTIGENS TO MEDIATE EARLY ACTIVATION OF INVARIANT NKT CELLS IN LYMPH NODES Ptrii Brrl, Polo Polzell, Andres Brukuer, Nio vn Rooijen, Gurdyl S.
SUPPLEMENTARY INFORMATION
doi: 1.138/nture862 humn hr. 21q MRPL39 murine Chr.16 Mrpl39 Dyrk1A Runx1 murine Chr. 17 ZNF295 Ets2 Znf295 murine Chr. 1 COL18A1 -/- lot: nti-dscr1 IgG hevy hin DSCR1 DSCR1 expression reltive to hevy
SUPPLEMENTARY INFORMATION
DOI: 1.138/n358 TLR2 nd MyD88 expression in murine mmmry epithelil supopultions. CD24 min plus MRU Myo-epithelil Luminl progenitor (CD61 pos ) Mture luminl (CD61 neg ) CD49f CD61 Reltive expression Krt5
Spleen VAT FMO. Nature Immunology: doi: /ni Ki67 DX5 CD27. CD11b 2B4 KLRG1 CD69 NKG2D CXCR3 CD44 NKG2A/C/E CD62L CD103 CD94 CD48.
IFN (% of ells) CD7 Marophages Medium NCR LPS PMA/Ionomyin CD IFN (% of ells) T ells Marophages B ells DX CD9 KLRG NKGD B CDL CD CD CXCR CD9 CD NKGA/C/E NCR Ly9h Ly9G Ly9d Ly9i Ly9/i/h FMO CD7 CD9a CD7
SUPPLEMENTARY INFORMATION
{ OI: 1.138/n31 Srifie n nlyze APs on week 1 s of iet 1 4 6 High-ft iet BrU High-ft iet BrU 4 High-ft iet BrU 6 High-ft iet BrU Lin - Lin - : C34 + : C9 + 1 1 3 1 4 1 5 C45 1 C34 1 1 1 1 3 1 4 1 5 S-1
SUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION doi:1.18/nture129 ontrol-dna -DNA CD49 Blood Lung e.98 +/-.9.71 +/-.2.29+/-.1 2.9 +/-.6 Bsophils (x1 )/ml 4 Bsophils ( x1 ) d f 45. 22.5 15 75 ontrol-dna ontrol-dna -DNA -DNA
SUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION doi: 1.138/nnno.211.41 Sili nd titnium dioxide nnoprtiles use pregnny omplitions in mie Kohei Ymshit, Ysuo Yoshiok, Kzum Higshisk, Kzuy Mimur, Yuki Morishit, Mstoshi Nozki, Tokuyuki
(% of adherent cells) *** PBL firm adhesion. Frequency (% ) 4 1 L 2 CXCR3 DP-2
Chemotxis (% of dded ells) PBL totl dhesion (N ells/mm 2 /1.1 6 PBL) Frequeny (% ) PBL firm dhesion Supplementry Figure 1 4 4 3 3 2 2 1.1-4 1-3 1.1.2. 1 1 8 6 4 2 Adiponetin ( g/ml) - + Adiponetin ( g/ml)
Supplementary figure 1
Supplementry figure 1 Dy 8 post LCMV infection Vsculr Assoc. Prenchym Dy 3 post LCMV infection 1 5 6.7.29 1 4 1 3 1 2 88.9 4.16 1 2 1 3 1 4 1 5 1 5 1.59 5.97 1 4 1 3 1 2 21.4 71 1 2 1 3 1 4 1 5 1 5.59.22
SUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION doi:.8/nture89 4 4 Ilr -/- Ilr -/- Ilr -/- Cspse- -/- As -/- Nlrp -/- Il8 -/- Ilr -/- Supplementl figure. Inresed severity of NASH in inflmmsome-defiient mie, ut not in Ilr-defiient
Supplemental Information. Lymphocytes Negatively Regulate NK Cell Activity. via Qa-1b following Viral Infection
Cell Reports, Volume 21 Supplementl Informtion Lymphocytes Negtively Regulte NK Cell Activity vi Q-1b following Virl Infection Hifeng C. Xu, Jun Hung, Aleksndr A. Pndyr, Elisbeth Lng, Yun Zhung, Christine
LHb VTA. VTA-projecting RMTg-projecting overlay. Supplemental Figure 2. Retrograde labeling of LHb neurons. a. VTA-projecting LHb
SUPPLEMENTARY INFORMATION Supplementl Figure 1 doi:10.1038/nture09742 Lterl 1.0 mm from midline mpfc BNST mpfc BNST Lterl 2.1 mm from midline LHA LHA Lterl 2.7 mm from midline SUPPLEMENTAL INFORMATION
SUPPLEMENTARY INFORMATION
DOI: 1.138/n2977 Numer of ells per field 6 4 2 P =.1 Orthotopi eum Normlized ventrl photon flux 1E7 1E6 1E5 1E4 1E3 1E2 n=8 n=9 1 2 3 4 5 6 Dys Dy54 1.5E5 2.4E7 d Mie with lymph node metstsis (%) 1 8 6
SUPPLEMENTARY INFORMATION
2 weeks high holesterol diet 2 weeks high holesterol diet 2 weeks high holesterol diet 2 μm Mrophges Crystls Hoehst μm Mrophges Crystls Hoehst Hoehst Crystls Mrophges 2 μm 2 μm Supplementry Fig. 1: Erly
Supplementary Figure 1. Scheme of unilateral pyramidotomy used for detecting compensatory sprouting of intact CST axons.
() BDA 2 weeks fter Py () AAVs Cre or GFP t P1 BDA 2 weeks fter Py CSMN CST () Py t P7 or 2 months () Py t 2 months Supplementry Figure 1. Sheme of unilterl pyrmidotomy used for deteting ompenstory sprouting
The microrna mir-31 inhibits CD8 + T cell function in chronic viral infection
A rt i l e s The mirorna mir-3 inhiits CD8 + T ell funtion in hroni virl infetion Howell F Moffett, Adm N R Crtwright, Hye-Jung Kim, Jernej Gode, Json Pyrdol, Trmo Äijö 3, Gustvo J Mrtinez,6, Anjn Ro,
TNF-α (pg/ml) IL-6 (ng/ml)
Xio, et l., Supplementry Figure 1 IL-6 (ng/ml) TNF-α (pg/ml) 16 12 8 4 1,4 1,2 1, 8 6 4 2 med Cl / Pm3CSK4 zymosn curdln Poly (I:C) LPS flgelin MALP-2 imiquimod R848 CpG TNF-α (pg/ml) IL-6 (ng/ml) 2 1.6
Overcoming Immune Tolerance Against Multiple Myeloma With Lentiviral Calnexin-engineered Dendritic Cells
The Amerin Soiety of Gene Therpy originl rtile Overoming Immune Tolerne Aginst Multiple Myelom With Lentivirl Clnexin-engineered Dendriti Cells Shuhong Hn 1, Bei Wng 1, Mtthew J Cotter 1, Li-Jun Yng 2,
Autocrine IL-2 is required for secondary population expansion of CD8 + memory T cells
Autorine IL-2 is required for seondry popultion expnsion of CD8 + memory T ells Soni Feu, Rmon Arens,2, Susn Togher & Stephen P Shoenerger 2 Nture Ameri, In. All rights reserved. Two ompeting theories
SUPPLEMENTARY INFORMATION
oi:1.138/nture1138 Supplementl Figure 1 Inflmmtory Monoytes Host ells CCR2 CCL2 Disseminting Tumor Cells Metstsis Assoite Mrophges VEGF Extrvstion & Metstti Seeing Supplementl Figure 1 The t from this
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
2 Nture Pulishing Group http://www.nture.om/nturemediine Inhiiting Stt3 signling in the hemtopoieti system eliits multiomponent ntitumor immunity Mrin Kortylewski 1,4, Miej Kujwski 1,4, Tinhong Wng 2,
Supplementary Figure 1
Supplementry Figure 1 Ncor1 Expression 2. 1.5 1..5. Muscle Liver Lmi Ppropi Kindey Pncres Lung Testis Bone Mrrow Thymus Spleen Peripherl Lymph nods Smll Intestine Ncor1 Expression 1.5 1..5. DN DP SP CD8
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
Regultory T ells prevent tstrophi utoimmunity throughout the lifespn of mie Jeong M Kim 1, Jeffrey P Rsmussen 1 & Alexnder Y Rudensky 1,2 Mie lking the trnsription ftor ( ) lk regultory T (T reg ) ells
SUPPLEMENTARY INFORMATION
DOI: 1.13/n7 Reltive Pprg mrna 3 1 1 Time (weeks) Interspulr Inguinl Epididyml Reltive undne..1.5. - 5 5-51 51-1 1-7 7 - - 1 1-1 Lipid droplet size ( m ) 1-3 3 - - - 1 1-1 1-1 1-175 175-3 3-31 31-5 >5
SUPPLEMENTARY INFORMATION
Prentl doi:.8/nture57 Figure S HPMECs LM Cells Cell lines VEGF (ng/ml) Prentl 7. +/-. LM 7. +/-.99 LM 7. +/-.99 Fold COX induction 5 VEGF: - + + + Bevcizum: - - 5 (µg/ml) Reltive MMP LM mock COX MMP LM+
A1/Bfl-1 expression is restricted to TCR engagement in T lymphocytes
(3) 1, 19 17 & 3 Nture Pulishing Group All rights reserved 13-97/3 $. www.nture.om/dd /Bfl-1 expression is restrited to TCR enggement in T lymphoytes C Vershelde 1, T Wlzer, P Gli 1, M-C Biémont 1, L Quemeneur
Alimonti_Supplementary Figure 1. Pten +/- Pten + Pten. Pten hy. β-actin. Pten - wt hy/+ +/- wt hy/+ +/- Pten. Pten. Relative Protein level (% )
Alimonti_Supplementry Figure 1 hy 3 4 5 3 Neo 4 5 5 Proe 5 Proe hy/ hy/ /- - 3 6 Neo β-tin d Reltive Protein level (% ) 15 1 5 hy/ /- Reltive Gene Expr. (% ) 15 1 5 hy/ /- Supplementry Figure 1 Chrteriztion
Chow KD CR HFD. Fed Fast Refed
Supplementry Figure 1 Control d/d Chow KD CR Fed Fst Refed Supplementry Figure 1: Liver expression in diet nd disese models. () expression in the livers of ontrol nd d/d mie. () expression in the livers
Origin of Triple hi and Triple lo T reg cells Triple hi and Triple lo T reg cells present in the thymus (Fig. 2a) could represent CD4 + GITR CD4 PD-1
Affinity for self ntigen selets with distint funtionl properties Len Wyss 1,2, Brin D Stdinski 3, Crolyn G King 1, Sonj Shllenerg 4, Nihols I MCrthy, Jun Young Lee 6,7, Krsten Kretshmer 4,8, Luigi M Terrino
SUPPLEMENTARY INFORMATION
doi:.8/nture98 : hr NEMO :5 hr IKK IKK NF-κB p65 p5 p65/-rel NF-κB p65 p5 p65/-rel Cytoplsm Cytoplsm p65/p5 Nuleus Nuleus NEMO IKK IKK d : hr > : hr p65/-rel NF- p65 p5 Cytoplsm Cytoplsm p65/p5 p65/-rel
Supplementary Figure 1
Supplementry Figure 1 c d Wistr SHR Wistr AF-353 SHR AF-353 n = 6 n = 6 n = 28 n = 3 n = 12 n = 12 Supplementry Figure 1 Neurophysiologicl properties of petrosl chemoreceptive neurones in Wistr nd SH rts.
SUPPLEMENTARY INFORMATION
doi:1.138/nture1228 Totl Cell Numer (cells/μl of lood) 12 1 8 6 4 2 d Peripherl Blood 2 4 7 Time (d) fter nti-cd3 i.p. + TCRβ + IL17A + cells (%) 7 6 5 4 3 2 1 Totl Cell Numer (x1 3 ) 8 7 6 5 4 3 2 1 %
SUPPLEMENTARY INFORMATION
doi:.38/nture277 d 25 25 2 Time from sound onset (ms) 25 25 2 Time from sound onset (ms) Firing rte (spikes/s) Firing rte (spikes/s).8.6..2 e f g h.8.6..2 Frtion of neurons Frtion of neurons N = 53 2 2
Tbp. Per Relative mrna levels Circadian Time. Liver weight/ body weight (%) n.s. Pernull
Liver weight/ ody weight (%) Dy Body weight (g) Reltive mrna levels Reltive mrna levels Reltive mrna levels Reltive mrna levels Dy Per1 Per2 Per3 Tp 8 2 8 2. 6 2 8 12162 Cirdin Time 3 2 1 2 1 1 8 12162
Targeting TSLP With shrna Alleviates Airway Inflammation and Decreases Epithelial CCL17 in a Murine Model of Asthma
Cittion: Moleulr Therpy Nulei Aids (216), e316; doi:1.138/mtn.216.29 Offiil journl of the Amerin Soiety of Gene & Cell Therpy www.nture.om/mtn Trgeting TSLP With shrna Allevites Airwy Inflmmtion nd Dereses
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
Essentil role of NKT ells produing IL-4 nd IL-13 in the development of llergen-indued irwy hyperretivity OMID AKBARI 1, PHILIPPE STOCK 1, EVERETT MEYER 1, MITCHELL KRONENBERG 2, STEPHANE SIDOBRE 2, TOSHINORI
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T- lymphocytes
Supporting Online Mteril for Heprnse promotes tumor infiltrtion nd ntitumor ctivity of -redirected T- lymphocytes IgnzioCrun, Brr Svoldo, VlentinHoyos, Gerrit Weer, Ho Liu, Eugene S. Kim, Michel M. Ittmnn,
PNEUMOVAX 23 is recommended by the CDC for all your appropriate adult patients at increased risk for pneumococcal disease 1,2 :
PNEUMOVAX 23 is recommended y the CDC for ll your pproprite dult ptients t incresed risk for pneumococcl disese 1,2 : Adults ged
Cos7 (3TP) (K): TGFβ1(h): (K)
IP#2: IP#1: Totl Lystes luiferse tivity (K): 6-4 - (K): luiferse tivity luiferse tivity (K): 2 1 RL-: - + + + + + Sm4-3F: + - + + + + MYC-Sm3: - - - - + + TβRI-HA(T204D): - - - + - + α-ha Luiferse Ativity
Supplementary Information
Supplementry Informtion Cutneous immuno-surveillnce nd regultion of inflmmtion y group 2 innte lymphoid cells Ben Roediger, Ryn Kyle, Kwok Ho Yip, Nitl Sumri, Thoms V. Guy, Brin S. Kim, Andrew J. Mitchell,
Effect of addition of Saccharomyces cerevisiae to the diet of laying hens in physiological traits and qualities attributes of the product eggs
IOSR Journl of Agriulture nd Veterinry Siene (IOSR-JAVS) e-issn: 2319-2380, p-issn: 2319-2372. Volume 7, Issue 12 Ver. III (De. 2014), PP 20-26 www.iosrjournls.org Effet of ddition of Shromyes erevisie
SEED Haematology. Looking deeper into inflammatory conditions from a laboratory and clinical perspective
SYSMEX EDUCATIONAL ENHANCEMENT AND DEVELOPMENT JULY 2018 SEED Hemtology Looking deeper into inflmmtory onditions from lortory nd linil perspetive Inflmmtion nd infetion re two different things, lthough
EFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS
EFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS Finl report sumitted to Dniso Animl Nutrition E. vn Heugten nd B. Frederik North Crolin Stte University, Deprtment of Animl Siene Summry The urrent
Department of Animal Resource and Science, Dankook University, Cheonan, Choongnam, , Republic of Korea
British Journl of Nutrition (1), 115, 57575 The Authors 1 doi:1.117/s711515857 Ltoillus idophilus modultes inflmmtory tivity y regulting the TLR nd NF-κB expression in porine peripherl lood mononuler ells
Lesions of prefrontal cortex reduce attentional modulation of neuronal responses. and synchrony in V4
Lesions of prefrontl ortex reue ttentionl moultion of neuronl responses n synhrony in V4 Georgi G. Gregoriou,, Anrew F. Rossi, 3 Leslie G Ungerleier, 4 Roert Desimone 5 Deprtment of Bsi Sienes, Fulty of
Effects of flurbiprofen on renal function in patients with moderate renal insufficiency
Br. J. lin. Phrm. (1992), 33, 385-393 ffets of fluriprofen on renl funtion in ptients with moderte renl insuffiieny M. D. MURRAY12, P. K. GRN', D. C. BRATR', A. K. MANATUNGA' & S. D. HALL' 'Division of
ARTICLES. Host-reactive CD8 + memory stem cells in graft-versushost. Yi Zhang, Gerard Joe, Elizabeth Hexner, Jiang Zhu & Stephen G Emerson
Host-retive CD8 + memory stem ells in grft-versushost disese Yi Zhng, Gerrd Joe, Elizeth Hexner, Jing Zhu & Stephen G Emerson Grft-versus-host disese (GVHD) is used y lloretive donor T ells tht trigger
Identification of TROP2 (TACSTD2), an EpCAM-Like Molecule, as a Specific Marker for TGF-b1-Dependent Human Epidermal Langerhans Cells
ORIGINAL ARTICLE Identifition of (TACSTD2), n -Like Moleule, s Speifi Mrker for TGF-1-Dependent Humn Epiderml Lngerhns Cells Gregor Eisenwort 1, Jennifer Jurkin 1, Night Ysmin 1, Thoms Buer 1, Bernhrd
NOTE: This table will be discontinued after this lot.
AS037-011 Rev. 11/14 ASSAY VALUES AND EXPECTED RANGES QCP DATA MONTHS: DEC, JAN, FEB Beckman Coulter STKS / MAXM / HMX LEVEL 1 + Lot No.: Exp. Date: LOT 871086 Parameter Mean Range WBC 10 3 /µl 4.0 ± 0.6
The Toxicity Evaluation of Phragmanthera incana (Klotzsch) Growing on Two Plant Hosts and Its Effect on Wistar Rats Haematology and Serum Biochemistry
Ademi Journl of Plnt Sienes 6 (2): 92-98, 201 ISSN 1995-8986 IDOSI Pulitions, 201 DOI: 10.5829/idosi.jps.201.6.2.5 The Toxiity Evlution of Phrgmnther inn (Klotzsh) Growing on Two Plnt Hosts nd Its Effet
SUPPLEMENTARY INFORMATION
doi:1.138/nture17 Men tumour dimeter (mm) 2 Rg2-/- 2 1 2 2 1 Control IgG!-CD8!-CD4 1 2 3 1 2 3 c Men tumour dimeter (mm) 2 2 1 d Ifnr1-/- Rg2-/- 2 2 1 Ifngr1-/- d42m1!ic 1 2 3 Dys post trnsplnt 1 2 3 Supplementry
Type I Interferons Interfere with the Capacity of mrna Lipoplex Vaccines to Elicit Cytolytic T Cell Responses
originl rtile Type I Interferons Interfere with the Cpity of Lipoplex Vines to Eliit Cytolyti T Cell Responses Ans De Beukeler 1, Chrlotte Pollrd 1,2, Sndr Vn Lint 3,4, Kenny Roose 4,5, Lien Vn Hoeke 4,5,
SUPPLEMENTARY INFORMATION
SUPPEMENTARY INFORMATION DOI: 1.138/ncb956 Norml CIS Invsive crcinom 4 months months b Bldder #1 Bldder # Bldder #3 6 months (Invsive crcinom) Supplementry Figure 1 Mouse model of bldder cncer. () Schemtic
Supplemental Materials for. Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to. FTY720 during neuroinflammation
Supplemental Materials for Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY7 during neuroinflammation This file includes: Supplemental Table 1. EAE clinical parameters of
Anti-Inflammatory Activity of Methanol Extract and Fractions from Alchemilla kiwuensis Engl. on LPS Activated Macrophages
Aville online on www.ijppr.om Interntionl Journl of Phrmognosy nd Phytohemil Reserh 217; 9(4); 473-481 DOI numer: 1.25258/phyto.v9i2.8117 Reserh Artile ISSN: 975-4873 Anti-Inflmmtory Ativity of Methnol
Supplementary Figure 1
Roles of endoplsmic reticulum stress-medited poptosis in -polrized mcrophges during mycocteril infections Supplementry informtion Yun-Ji Lim, Min-Hee Yi, Ji-Ae Choi, Jung-hwn Lee, Ji-Ye Hn, Sung-Hee Jo,
SUPPLEMENTARY INFORMATION
doi: 10.1038/nture07679 Emryonic Stem (ES) cell Hemngiolst Flk1 + Blst Colony 3 to 3.5 Dys 3-4 Dys ES differentition Sort of Flk1 + cells Supplementry Figure 1. Chrcteristion of lst colony development.
Replacement Value of Low Tannin Sorghum (Sorghum bicolor) for Maize in Broiler Chickens Diets in the Semi-Arid Zone of Nigeria
Interntionl Journl of Poultry Siene 11 (5): 333-337, 2012 ISSN 1682-8356 Asin Network for Sientifi Informtion, 2012 Replement Vlue of Low Tnnin Sorghum (Sorghum iolor) for Mize in Broiler Chikens Diets
AJ PUTT. Hematology. Chemistry. Species: Canine Gender: Female Year of Birth: 2013 Client: PUTT
Speies: Cnine Gender: Femle Yer of Birth: 2013 Client: PUTT Requisition #: 9034-12 Aession #: W2152816 Aount Code: 72364 Veterinrin: CARTER Pnel/Profile: Tik Pnel Add-on Senior Profile with L 4Dx Plus
Type II monocytes modulate T cell-mediated central nervous system autoimmunity
Type II monocytes modulte T cell-medited centrl nervous system utoimmunity Mrtin S. Weer, Thoms Prod homme, Swsn Youssef, Shnnon E. Dunn, Cynthi D. Rundle, Lind Lee, Jun C. Ptrroyo, Olf Stüve, Rymond A.
Impaired gp100-specific CD8 + T-Cell Responses in the Presence of Myeloid-Derived Suppressor Cells in a Spontaneous Mouse Melanoma Model
ORIGINAL ARTICLE Impired gp1-speifi CD8 + T-Cell Responses in the Presene of Myeloid-Derived Suppressor Cells in Spontneous Mouse Melnom Model Dvid G. Mirhofer 1, Dniel Ortner 1, Christoph H. Tripp 1,2,
... Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. immunology letters to nature
Supplementry informtion is ville in Nture s World-Wide We site (http:// www.nture.om) or s pper opy from the London editoril offie of Nture. Aknowledgements Supported in prt y grnts from the NIH (A.A.,
Olfactory behavior and physiology are disrupted in prion protein knockout mice
Olftory ehvior nd physiology re disrupted in prion protein knokout mie Clire E Le Pihon 1, Mtthew T Vlley 1, Mgdlini Polymenidou 2,3, Alexnder T Chesler 1, Botir T Sgdullev 1,3, Adrino Aguzzi 2 & Sturt
Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm
Adipocyte in vsculr wll cn induce the rupture of dominl ortic neurysm Hiron Kugo 1 *, Nouhiro Zim 1 *, Hiroki Tnk 2 *, Youhei Mouri 1, Kenichi Yngimoto 3, Kohsuke Hymizu 3,4, Keisuke Hshimoto 1, Tkeshi
Effect of Adding Cinnamomum cassia Powder to the Ration in Some Blood Traits of Broiler Ross 308
Journl of Nturl Sienes Reserh ISSN 2224-186 (Pper) ISSN 222-0921 (Online) Effet of Adding Cinnmomum ssi Powder to the Rtion in Some Blood Trits of Broiler Ross 08 Ali Slim AL- mmury University of AL-Qsim
Supplementary Information
Supplementry Informtion Non-nonil prevents skeletl ging n inflmmtion y inhiiting NF-κB Bo Yu, Ji Chng, Yunsong Liu, Jiong Li, Kreen Kevork, Khli Al Hezimi, Dn T. Grves, No-Hee Prk, Cun-Yu Wng Supplementry
Exogenous mesenchymal stem cells localize to the kidney by means of CD44 following acute tubular injury
originl rtile http://www.kidney-interntionl.org & 27 Interntionl Soiety of Nephrology see ommentry on pge 389 Exogenous mesenhyml stem ells lolize to the kidney y mens of CD44 following ute tuulr injury
ANGPTL binding ANGPTL binding ANGPTL4 GST ANGPTL5 ANGPTL6 ANGPTL7. A5+LILRB2 Fc. A5+Tie-2 Fc 10,000 7,500. Tie-2 Fc LILRB2 Fc. 5,000 K d = 5.
doi:1.138/nture1195 ; Inhiitory reeptors ind ANGPTLs nd support < lood stem ells nd leukemi development Junke Zheng 1,2, Msto Umikw 1,3, Chngho Cui 1, Jiyun Li 1, Xioli Chen 1, Chozheng Zhng 1, HongDinh
Clinical Study Report Synopsis Drug Substance Naloxegol Study Code D3820C00018 Edition Number 1 Date 01 February 2013 EudraCT Number
EudrCT Number 2012-001531-31 A Phse I, Rndomised, Open-lbel, 3-wy Cross-over Study in Helthy Volunteers to Demonstrte the Bioequivlence of the Nloxegol 25 mg Commercil nd Phse III Formultions nd to Assess
Interplay of LRRK2 with chaperone-mediated autophagy
Interply of with hperone-medited utophgy Smnth J Orenstein,, Sheng-Hn Kuo,, Inmuld Tsset,,, Espernz Aris,, Hiroshi Kog,, Irene Fernndez-Crs, Etty Cortes,5, Lwrene S Honig,5, Willim Duer 6, Antonell Consiglio,7,
Effects of Plant Sphingolipids on Inflammatory Stress in Differentiated Caco-2 Cells
Journl of Oleo Siene Copyright 2017 y Jpn Oil Chemists Soiety doi : 10.5650/jos.ess17171 J. Oleo Si. 66, (12) 1337-1342 (2017) NOTE Effets of Plnt Sphingolipids on Inflmmtory Stress in Differentited Co-2
Nwokoro, Smart O. and Joseph O.I. Obasuyi Department of Animal Science, Faculty of Agriculture, University of Benin, Benin City, Nigeria
Interntionl Journl of Poultry Siene 5 (3): 96-300, 006 ISSN 168-8356 Asin Network for Sientifi Informtion, 006 Prtil Sustitution of Soyen Mel wi Bredfruit (Artorpus ltilis) Seed Mel in Broiler Strter Diets:
Resident c-kit þ cells in the heart are not cardiac stem cells
Reeived 3 Jul 05 Aepted Sep 05 Pulished 30 Ot 05 DOI: 0.038/nomms970 OPEN Resident -kit þ ells in the hert re not rdi stem ells Nisht Sultn, *, Lu Zhng, *, Jinyun Yn, *, Jiqiu Chen, Weiin Ci, Sheguft Rzzque,
Capsid-specific T-cell Responses to Natural Infections With Adeno-associated Viruses in Humans Differ From Those of Nonhuman Primates
originl rtile See pge 1923 Cpsi-speifi T-ell Responses to Nturl Infetions With Aeno-ssoite Viruses in Humns Differ From Those of Nonhumn Primtes Hu Li 1, Mrio O Lsro 1, Bei Ji 1,2, Shih Wen Lin 1,3, Lriss
Targeted delivery of antigen to intestinal dendritic cells induces oral tolerance and prevents autoimmune diabetes in NOD mice
Dietologi (218) 61:1384 1396 https://doi.org/1.17/s125-18-4593-3 ARTICLE Trgeted delivery of ntigen to intestinl dendriti ells indues orl tolerne nd prevents utoimmune dietes in D mie Yulin Chen 1 & Jie
Activation of Akt as a Mechanism for Tumor Immune Evasion
The Amerin Soiety of Gene Therpy originl rtile Ativtion of Akt s Mehnism for Tumor Immune Evsion Kyung Hee Noh 1, Te Heung Kng 1, Jin Hee Kim 1, Sr I Pi 2, Ken Y Lin 3, Chien-Fu Hung 4, T-C Wu 4 7 nd Te
Laminar sources of synaptic input to cortical inhibitory interneurons and pyramidal neurons
rtiles Lminr soures of synpti input to ortil inhiitory interneurons nd pyrmidl neurons J. L. Dntzker nd E. M. Cllwy Systems Neuroiology Lortories, The Slk Institute for Biologil Studies, N. Torrey Pines
supplemental Figure 1
supplemental Figure 1 A T cell T1 anti-ny-eso-117-16/hla-a*:1 CDζ CH/CH scfv B T cell T1 anti-ny-eso-117-16/hla-a*:1 CDζ CH/CH scfv C T cell BW1/6 anti-cea CDζ CH/CH scfv supplemental Figure 1.79.9.87
e-figure 1. The design of the study.
e-figure 1. The design of the study. NDM, no diabetes; DM, diabetes; TB, tuberculosis; SN, sputum smear negative; SP, sputum smear positive; AFB, acid fast bacilli. e-figure 2. Representative H&E (A) and
Transient Removal of CD46 Is Safe and Increases B-cell Depletion by Rituximab in CD46 Transgenic Mice and Macaques
The Amerin Soiety of Gene & Cell Therpy originl rtile Trnsient Removl of CD46 Is Sfe nd Inreses B-ell Depletion by Rituximb in CD46 Trnsgeni Mie nd Mques Ines Beyer 1,6, Hu Co 1, Jons Persson 1, Hongjie
Hydrogen sulfide-induced inhibition of L-type Ca 2+ channels and insulin secretion in mouse pancreatic beta cells
Dietologi (213) 56:533 541 DOI 1.17/s125-12-286-8 ARTICLE Hydrogen sulfide-indued inhiition of L-type C 2 hnnels nd insulin seretion in mouse pnreti et ells G. Tng & L. Zhng & G. Yng & L. Wu & R. Wng Reeived:
Fawzia Y. Shata, Sayed G. Hassan, Walid S. El-Nattat, Hassan M. Desouky, Amira H. Mohamed and Alaa R. Ahmed
Glol Journl of Phrmology 8 (4): 665-672, 2014 ISSN 1992-0075 IDOSI Pulitions, 2014 DOI: 10.5829/idosi.gjp.2014.8.4.8614 Protetive Effets of Vitmin E, Selenium nd Zin Supplementtion on Hemtologil nd Some
The same genomic region conditions clonal deletion and clonal deviation to the CD8 and regulatory T cell lineages in NOD versus C57BL/6 mice
The sme genomi region onditions lonl deletion nd lonl devition to the nd regultory T ell lineges in NOD versus C57BL/6 mie Phillip D. Holler, Tetsuy Ymgt, Wenyu Jing, Mrkus Feuerer, Christophe Benoist*,
DOI: 10.1038/nc2331 PCre;Ros26R 12 h induction 48 h induction Vegfr3 i EC c d ib4 24 h induction VEGFR3 e Fold chnge 1.0 0.5 P < 0.05 Vegfr3 i EC Vegfr3 Figure S1 Cre ctivtion leds to genetic deletion
Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
Supplementry Informtion Microtuule-driven sptil rrngement of mitochondri promotes ctivtion of the NLRP3 inflmmsome Tkum Misw 1,2, Michihiro Tkhm 1,2, Ttsuy Kozki 1,2, Hnn Lee 1,2, Jin Zou 1,2, Ttsuy Sitoh
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
BTLA is lymphoyte inhiitory reeptor with similrities to CTLA-4 nd PD-1 Norihiko Wtne 1,5, My Gvrieli 1, John R Sedy 1, Jinfei Yng 1,5, Frnes Fllrino 2, Susn K Loftin 1, Mihelle A Hurhl 1, Ntlie Zimmermn
LETTER. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
doi:.8/nture98 Impired hydroxyltion of -methylytosine in myeloid ners with mutnt TET Myunggon Ko {, Yun Hung {, Ann M. Jnkowsk, Utz J. Ppe,, Mmt Thilini, Hozef S. Bndukwl, Jungeun An {, Edwrd D. Lmperti,
Hippocampal CA1 pyramidal cells form functionally distinct sublayers
r t i l e s Hippompl CA pyrmidl ells form funtionlly distint sulyers Kenji Mizuseki, Kmrn Di,2, Ev Pstlkov,2 & György Buzsáki 2 Nture Ameri, In. All rights reserved. Hippompl CA pyrmidl neurons hve frequently
Chronic high-sodium diet intake after weaning lead to neurogenic hypertension in adult Wistar rats
Chronic high-sodium diet intke fter wening led to neurogenic hypertension in dult Wistr rts 1 Pul Mglhães Gomes; 2 Rento Willin Mrtins Sá; 1 Giovn Lopes Aguir; 1 Milede Hnner Sriv Pes; 1 Andréi Crvlho
Inhibitory effect of p38 mitogen-activated protein kinase inhibitors on cytokine release from human macrophages
British Journl of Phrmology (26) 149, 393 44 & 26 Nture Pulishing Group All rights reserved 7 1188/6 $3. www.rjphrmol.org RESEARCH PAPER Inhiitory effet of p38 mitogen-tivted protein kinse inhiitors on
% Inhibition of MERS pseudovirus infection. 0 h 0.5 h 1 h 2 h 4 h 6 h Time after virus addition
% Inhiition of MERS pseudovirus infection 1 8 h.5 h 1 h 2 h 4 h 6 h Time fter virus ddition Supplementry Figure S1. Inhiition of on MERS pseudovirus infection t the different intervls postinfection. A
BATF regulates collagen-induced arthritis by regulating T helper cell differentiation
Prk et l. Arthritis Reserh & Therpy (218) 2:161 https://doi.org/1.1186/s1375-18-1658- RESEARCH ARTICLE Open Aess BATF regultes ollgen-indued rthritis y regulting T helper ell differentition Sng-Heon Prk
Ulk λ PPase. 32 P-Ulk1 32 P-GST-TSC2. Ulk1 GST (TSC2) : Ha-Ulk1 : AMPK. WB: Ha (Ulk1) : Glu. h CON - Glu - A.A WB: LC3 AMPK-WT AMPK-DKO
DOI: 10.1038/ncb2152 C.C + - + - : Glu b Ulk1 - - + λ PPse c AMPK + - + + : ATP P-GST-TSC2 WB: Flg (Ulk1) WB Ulk1 WB: H (Ulk1) GST (TSC2) C.C d e WT K46R - + - + : H-Ulk1 : AMPK - + - + + + AMPK H-Ulk1
SUPPLEMENTARY INFORMATION
DOI:.38/nc393 Nnog DAPI Nnog/DAPI c-jun DAPI c-jun/dapi c e Reltive expression to Gpdh mescs ( Feeder free) mescs ( Feeder) MEFs.5 MEFs ipscs ESCs..5 p=.24 p=.483 p=.22. JunB JunD Fos Fr Fr2 ATF2 ATF3
Supplementary Figure S1
Supplementry Figure S1 d MAP2 GFAP e MAP2 GFAP GFAP c f Clindin GFAP Supplementry Figure S1. Neuronl deth nd ltered strocytes in the rin of n ffected child. Neuron specific MAP2 ntiody stining in the hippocmpus
Aquaporin-9-expressing neutrophils are required for the establishment of contact hypersensitivity
Supplemental Material quaporin-9-expressing neutrophils are required for the establishment of contact hypersensitivity atharina Sagita Moniaga 1, Sachiko Watanabe 1, Tetsuya Honda 1, 2, Søren Nielsen 3,
Erucin Exerts Anti-Inflammatory Properties in Murine Macrophages and Mouse Skin: Possible Mediation through the Inhibition of NFκB Signaling
Int. J. Mol. Si. 213, 14, 2564-2577; doi:1.339/ijms1412564 Artile OPEN ACCESS Interntionl Journl of Moleulr Sienes ISSN 1422-67 www.mdpi.om/journl/ijms Eruin Exerts Anti-Inflmmtory Properties in Murine
Effect of Moringa (Moringa oleifera) Inclusion in Cassava Based Diets Fed to Broiler Chickens
Interntionl Journl of Poultry Siene 9 (4): 363-367, 2010 ISSN 1682-8356 Asin Network for Sientifi Informtion, 2010 Effet of Moring (Moring oleifer) Inlusion in Cssv Bsed Diets Fed to Broiler Chikens 1
Supplementary information for: Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage
Supplementry informtion for: Low one mss nd chnges in the osteocyte network in mice lcking utophgy in the osteolst linege Mrilin Piemontese, Meld Onl, Jinhu Xiong, Li Hn, Jeff D. Thostenson, Mri Almeid,