THE MEDICAL MANAGEMENT OF AIDS

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1 Department of Medicine University of California, San Francisco School of Medicine THE MEDICAL MANAGEMENT OF AIDS A Comprehensive Review of HIV Management December 9-11, 2004 Four Seasons Hotel University of California San Francisco

2 THE MEDICAL MANAGEMENT OF AIDS A Comprehensive Review of HIV Management December 9-11, 2004 Four Seasons Hotel, T he medical care of HIV/AIDS patients continues to become more complex. Optimum clinical care depends on understanding more sophisticated concepts of pathogenesis and laboratory monitoring. To keep pace, we invite you to join a distinguished faculty for a Comprehensive Update in HIV Management from December 9-11, 2004 in. This course provides the active clinician with a comprehensive review of the science and application of HIV therapy. Lectures are presented by a group of leading clinicians and researchers who are also dedicated to teaching in their area of expertise. Topics addressed include current dilemmas in antiretroviral therapy, the nature of the immune response to HIV therapy, post exposure pro-phylaxis, common metabolic and drug toxicities as well as HIV /HCV co-infection. In addition, atten-tion is devoted to the unique management challenges that accompany caring for women and adolescents. This course is designed to familiarize attendees with the latest concepts in HIV science and medicine. Ample time for discussion is included. In recognizing the many challenges arising from the improvements of HIV therapy, the lunch hour on Thursday and Friday will be dedicated to focused small group sessions on relevant topics. Now in it s 16th year, this symposium is well designed for practicing clinicians including internists, family practitioners, infectious disease specialists, nurse practitioners and physician's assistants. We are finalizing the list of topics and faculty for our 2004 course, but want you to have an early chance to add this to your December calendar. The course outline will be forwarded to you with your registration confirmation. This symposium is presented by the Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, School of Medicine and the Positive Health Program, San Francisco General Hospital. This symposium is sponsored by the University of California, San Francisco School of Medicine. EDUCATIONAL OBJECTIVES After attending this course, participants should be able to describe: Recent changes in the epidemiology of AIDS internationally and nationally; Current strategies in the prevention of HIV transmission and medication adherence; New developments in the understanding of HIV pathogenesis; Current drug interactions and metabolic toxicities from anti-retroviral therapy and rational approaches to treatment; Antiretroviral resistance and current strategies for viral load monitoring and salvage therapy; Current recommendation for the management of acute HIV, post exposure prophylaxis (PEP), vertical transmission, pediatric AIDS, women and AIDS and HCV/HIV co-infection; ACCREDITATION The University of California, San Francisco School of Medicine (UCSF) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. UCSF designates this educational activity for a maximum of category 1 credits toward the American Medical Association (AMA) Physician s Recognition Award. Each physician should claim only those hours of credit actually spent in the activity. AAFP: Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending. Nurses: For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA category 1 credit issued by organizations accredited by the ACCME. New developments in AIDS malignancies and HIV related dermatologic, pulmonary, CNS, and psychiatric manifestations.

3 Course Schedule THE MEDICAL MANAGEMENT OF AIDS December 9-11, 2004 WEDNES DAY - December 8 FRID AY - December 10 5:00pm Registration Open Moderator: Paul Volberding, M.D. THU R S DAY - December 9 7:00am Registration and Continental Breakfast 8:00 Introduction Paul Volberding, M.D. 8:05 Scaling Up On a Country Level HIV/AIDS: A Review of the Issues Diane Havlir, M.D. 8:35 An International Perspective Robert Scott, M.D. 9:05 Delivering Care in Uganda from A to Z Merle Sande, M.D. 9:35 The Challenge of HIV Prevention Harold Jaffe, M.D. 10:10 Break 10:25 Deciphering HIV Pathogenesis Warner Greene, M.D. 11:00 New Approaches to Immune Reconstitution: A Potential Role for Enhancement of T Cell Production Laura Napolitano, M.D. 11:30 Clinical Implications of Immune Reconstitution Mark Jacobson, M.D. 12:00 Panel Discussion Paul Volberding, M.D. 12:30 Lunch/Breakout Sessions 1. Oral Manifestations of AIDS Deborah Greenspan, D.Sc., B.D.S. 2. Managing Pharmacology Issues in HIV Medicine Ian McNichol, PharmD 3. Interesting Cases in STD Medicine Jeffrey Klausner, M.D. 4. Osteopenia and Osteoporosis: Are They a Problem in HIV Medicine? 1:30 Clinical Issues in HIV Pharmacokinetics Ed Acosta, M.D. 2:15 Clinical Use of Resistance Testing Robert Grant, M.D. 2:45 Break 3:15 Initiating HAART When to Start and What to Use Paul Volberding, M.D. 4:00 Panel Discussion 4:30 Reception 7:00am Continental Breakfast 8:00 Salvage Therapy: When to Switch, When to Stop Steven Deeks, M.D. 8:40 Managing Adherence in HIV Medicine Valerie Stone, M.D. 9:10 Metabolic Complications of HIV and its Therapy Morris Schambelan, M.D. 9:40 Break 10:10 Clinical Management of Metabolic Disease Judith Currier, M.D. 10:50 Cardiovascular Disease and HIV Priscilla Hsue, M.D. 11:20 Panel Discussion Diane Havlir, M.D. 12:10 Pick Up Lunch 12:30 Small Group Workshops 1. Managing Diabetes in HIV Infected Patients Daniel Wlodarczyk, M.D. 2. Interesting Clinical Cases in HIV Resistance Harry Lampiris, M.D. 3. Managing Peripheral Neuropathy Cherly Jay, M.D. 1:30 Acute HIV Frederick Hecht, M.D. 2:00 Post Exposure Prophylaxis Following Sexual Exposure Michelle Roland, M.D. 2:30 Interesting Cases in STD Medicine Gail Bolan, M.D. 3:00 Break 3:30 Interesting Clinical Cases in HIV Medicine Harry Hollander, M.D. 4:00 HIV Management Strategies for Illicit Drug Users Jacqueline Tulsky, M.D. 4:30 Panel Discussion of PM speakers Diane Havlir, M.D. 5:00 Adjourn COURSE CHAIRS Paul A. Volberding, M.D. Professor and Vice Chair of Medicine; Chief of the Medical Service, Veterans Affairs Medical Center, San Francisco; Co-Director, UCSF-GIVI Center for AIDS Research Diane V. Havlir, M.D. Professor of Medicine, Chief, HIV/AIDS Division Director, Positive Health Program University of California, San Francisco Meg D. Newman, M.D. Associate Professor of Clinical at San Francisco General Hospital; Director, AIDS in-patient consult service, PHP- HIV Clinical Scholars Fellowship

4 Course Faculty y SATURDAY - December 11 Moderator: Paul Volberding, M.D. 7:00am Continental Breakfast 8:00 Perinatal HIV Deborah Cohan, M.D., MPH 8:30 Update in Women and HIV 9:00 Adolescents and HIV: The Unmet Challenge Andrew Pavia, M.D. 9:30 Break 10:00 HIV Dermatology Toby Maurer, M.D. 10:30 HCV/HIV & Hepatitis C Co-infection: Dual Dilemmas Teresa Wright, M.D. 11:00 Anal Dysplasia in HIV Positive Men and Women: An Update Joel Palefsky, M.D. 11:30 Panel Discussion of AM Speakers Paul Volberding, M.D 12:00 Lunch on Own 1:00 TB and HIV Charles L. Daley, M.D. 1:30 HIV Malignancies Donald Abrams, M.D. 2:00 HIV-Associated Pulmonary Disease: Classic and Challenging Cases for the Clinician Laurence Huang, M.D. 2:40 Break 3:00 Update in HIV Neurology Cheryl Jay, M.D. 3:30 Panel Discussion of PM Speakers 4:10 Adjourn COURSE FACULT Y (University of California, San Francisco, School of Medicine unless otherwise noted) Donald I. Abrams, M.D. Professor of Clinical Medicine, Chief Hemotology/Oncology, San Francisco General Hospital, UCSF Edward P. Acosta, Pharm.D Assistant Professor, University of Alabama at Birmingham, Division of Clinical Pharmacology Gail A. Bolan, M.D. Assistant Clinical Professor of Medicine; Chief, Sexually Transmitted Disease Control Branch, California Department of Health Services, Berkeley Deborah Cohan, M.D., MPH Assistant Clinical Professor, Department of Obstetrics, Gynecology and Reproductive Sciences; Medical Director, Bay Area Perinatal AIDS Center (BAPAC) Judith Currier, M.D., MSc, Professor of Medicine; Associate Director; Center for Clinical AIDS Research and Education; David Geffen School of Medicine; University of California, Los Angeles Charles L. Daley, M.D. Associate Professor of Medicine; Director of Chest Clinic, San Francisco General Hospital; Medical Director, Francis J. Curry National Tuberculosis Training Center Steven Deeks, M.D. Associate Clinical Professor of Medicine, Positive Health Program, San Francisco General Hospital Robert M. Grant, M.D., MPH Assistant Professor of Medicine, UCSF; Assistant Investigator, Gladstone Institute of Virology and Immunology; Director, Gladstone/UCSF Laboratory of Clinical Virology Warner C. Greene, M.D., Ph.D. Director, Gladstone Institute of Virology and Immunology; Professor of Medicine, Microbiology and Immunology, University of California, San Francisco; Co- Director, UCSF-GIVI Center for AIDS Research Deborah Greenspan, D.Sc., B.D.S., FDSRCS Edin Professor of Frederick Hecht, M.D. Associate Professor of Medicine, University of California San Francisco Harry Hollander, M.D. Professor of Clinical Medicine; Director, Categorical Medicine Residency Program Priscilla Hsue, M.D. Assistant Professor of Medicine, Division of Cardiology, San Francisco General Hospital Laurence Huang, M.D. Associate Professor of Clinical Medicine; Chief, AIDS Chest Clinic, San Francisco General Hospital Mark A. Jacobson, M.D. Professor of Medicine in Residence; Director, UCSF Center for AIDS Research Clinical Care, Positive Health Program, SFGH Harold W. Jaffe, M.D. Acting Director, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA Cheryl A. Jay, M.D. Associate Professor of Neurology, University of California San Francisco Jeffrey D. Klausner, M.D., M.P.H. Assistant Clinical Professor of Medicine, Divisions of Infectious Diseases, AIDS and Oncology; Director, STD Prevention and Control Services, San Francisco Department of Public Health Harry W. Lampiris, M.D. Associate Professor of Clinical Medicine; Infectious Disease Section, Department of Medicine, San Francisco VA Medical Center Toby A. Maurer, M.D. Assistant Professor of Dermatology; Chief of Dermatology, San Francisco General Hospital Ian McNicholl, PharmD, BCPS (ID) Clinical Assistant Professor, School of Pharmacy; Clinical Pharmacy Specialist Laura A. Napolitano, M.D. Assistant Adj. Professor of Medicine, Division of Infectious Diseases; Assistant Investigator, Gladstone Institute of Virology and Immunology Joel M. Palefsky, M.D. Associate Professor of Medicine and Laboratory Medicine, University of California San Francisco Andrew Pavia, M.D. Professor of Pediatrics, Adjunct Professor of Medicine; Chief, Division of Pediatric Infectious Diseases, University of Utah, School of Medicine, Salt Lake City, UT Michelle Roland, M.D. Assistant Professor of Medicine, University of California San Francisco AIDS Program, San Francisco General Hospital Merle A. Sande, M.D., MACP Professor of Internal Medicine and Program Director; Co-Chair Academic Alliance of AIDS Care and Prevention in Africa Morris Schambelan, M.D. Professor of Medicine, UCSF; Director, General Clinical Research Center; Chief Division of Endocrinology and Metabolism, San Francisco General Hospital Robert Scott, M.D. Alta Bates Hospital, Summit Medical Center Valerie E. Stone, M.D., MPH Associate Chief, General Medicine Unit, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School Jacqueline Tulsky, M.D. Associate Clinical Professor of Medicine, San Francisco General Hospital; HIV Medical Care Coordinator, San Francisco General Hospital Methadone Clinic Daniel Wlodarczyk, M.D. Clinical Professor of Medicine, San Francisco General Hospital Teresa L. Wright, M.D. Professor of Medicine, UCSF; Chief, Division of Gastroenterology, San Francisco VA Medical Center

5 Course Location o n & Registration g s a tion ACCOMMODATIONS A chic retreat on Market Street, Four Seasons Hotel San Francisco is set in the heart of the vibrant Yerba Buena Arts District - two blocks from Union Square, the Moscone Center and the Museum of Modern Art. It is also delightfully close to San Francisco's favorite visitor attractions and some of the most exciting shopping venues on the continent. AIR TRANSPORTATION Special arrangements have been made with Montgomery Travel. Simply call 800/ or fax your travel request to 415/ and specify this meeting. A travel specialist will assist you with air reservations and local area travel plans. In addition to offering lower rates than the published airfares, ticketed passengers may take advantage of the 24- hour emergency service. There is a $20 service fee. RENTAL CAR Hertz is offering special rates for participants of this conference; simply call 800/ and refer to identification number CV #030D0034, or call your travel agent. Advance reservations are recommended. A block of guest rooms have been reserved at the Four Seasons Hotel with group rates of $229 single or double occupancy. Reservations must be received by November 9, 2004 to guarantee availability of accommodations. After this date, rooms will be provided on a space and rate-available basis only. The hotel reservation form is attached for your convenience. However, if you phone in your reservation, you must identify yourself as a member of this course to receive the special rate. Location: Four Seasons Hotel 757 Market Street San Francisco, CA Phone: 415/ REGISTRATION INFORMATION Register online at medicine.ucsf.edu/cme or cme.ucsf.edu To register with Visa/MasterCard please call 415/ To register by check, please call 415/ to obtain a registration form. For detailed course information please call 415/ Refer to course DMK05465 when calling. Date: Thursday, December 9 - Saturday, December 11, 2004 Refund policy: Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date. PARKING Valet parking is available at the hotel. Entrance is off of Third Street. Hearst Parking Center 45 3rd Street Fifth & Mission Yerba Buena Garage 833 Mission Street at Fifth (3 block walk) Ellis-O Farrell Garage 123 O Farrell at Powell NEW! Register by September 1, 2004 and receive the Early Bird Discount: Registration Fee: Early Bird After September 1, 2004 $495 $550 Physicians; $300 $385 Allied Health Professionals, interns and residents with an accompanying letter of status verification. Registration fee includes: Detailed course syllabus Daily continental breakfast and luncheon on Thursday. * * Additional meals and accommodations are not included.

6 038 University of California, San Francisco Department of Medicine, CME UCSF Box 0656 San Francisco, CA University of California San Francisco Upcoming CME Infectious Diseases in Clinical Practice February 20-25, 2005 Kauai, Hawaii Psychiatry for Primary Care: An Integrated Approach to Common Problems in Mental Health March, 2005 Heart Disease in Women March 5, 2005 Orlando, Florida Management of the Hospitalized Patient September 29 - October 2, 2004 Advances in Infectious Disease May 14-16, 2005 For information on our courses, visit us online at medicine.ucsf.edu/cme or call 415/ This course is self-supporting and receives no state funding. Nonprofit Org. U.S. Postage PAID University of California DMK05465

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